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Aliases for ZNF837 Gene

Aliases for ZNF837 Gene

  • Zinc Finger Protein 837 2 3 5

External Ids for ZNF837 Gene

Previous GeneCards Identifiers for ZNF837 Gene

  • GC19M063571
  • GC19M058878
  • GC19M055188

Summaries for ZNF837 Gene

GeneCards Summary for ZNF837 Gene

ZNF837 (Zinc Finger Protein 837) is a Protein Coding gene. An important paralog of this gene is ZNF497.

UniProtKB/Swiss-Prot for ZNF837 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF837 Gene

Genomics for ZNF837 Gene

Regulatory Elements for ZNF837 Gene

Enhancers for ZNF837 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G058406 1.4 ENCODE dbSUPER 10.1 -27.4 -27431 3.7 HDGF CREB3L1 AGO1 ARID4B SIN3A DMAP1 ZBTB7B YY1 SLC30A9 ZNF766 ZNF584 LOC105372483 ZNF132 ZNF17 LOC100128398 ENSG00000268912 ZNF549 ZSCAN18 ZNF418 ENSG00000268201
GH19G058379 1.2 ENCODE 11.7 0.0 -26 2.9 CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 SLC30A9 ZNF143 ZNF263 SP3 NFYC ZSCAN18 ZNF584 LOC100128398 TRIM28 ZNF548 ZNF606 ZNF134 RPS5 ZNF132 ZNF549
GH19G058571 1.4 ENCODE dbSUPER 9.9 -193.1 -193053 4.5 MLX CREB3L1 AGO1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 ZSCAN18 LOC100128398 TRIM28 ZNF418 ENSG00000268201 LOC105372482 ZNF606 LOC105372483 MZF1 ENSG00000268049
GH19G058394 1.4 Ensembl ENCODE dbSUPER 8.2 -15.1 -15090 3.4 PKNOX1 PTBP1 AGO1 SIN3A KLF17 GLIS2 SCRT2 RCOR1 KLF7 PAF1 RPS5 ZNF837 ZNF584 ZNF446 ENSG00000268912 ZNF814 ENSG00000268307 GC19M058391
GH19G058181 1.1 ENCODE 9.9 +197.8 197824 2.5 HDGF PKNOX1 CREB3L1 ARNT AGO1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B ZNF134 ZNF549 ZNF606 ZNF773 ZNF17 ZNF418 ZNF550 ZNF417 ZNF256 ZNF543
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF837 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF837 Gene

Chromosome:
19
Start:
58,367,618 bp from pter
End:
58,381,060 bp from pter
Size:
13,443 bases
Orientation:
Minus strand

Genomic View for ZNF837 Gene

Genes around ZNF837 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF837 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF837 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF837 Gene

Proteins for ZNF837 Gene

  • Protein details for ZNF837 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96EG3-ZN837_HUMAN
    Recommended name:
    Zinc finger protein 837
    Protein Accession:
    Q96EG3

    Protein attributes for ZNF837 Gene

    Size:
    531 amino acids
    Molecular mass:
    58078 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF837 Gene

Post-translational modifications for ZNF837 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF837 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF837 Gene

Domains & Families for ZNF837 Gene

Gene Families for ZNF837 Gene

Suggested Antigen Peptide Sequences for ZNF837 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96EG3

UniProtKB/Swiss-Prot:

ZN837_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF837: view

Function for ZNF837 Gene

Molecular function for ZNF837 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF837 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF837: view

Phenotypes for ZNF837 Gene

GenomeRNAi human phenotypes for ZNF837:
genes like me logo Genes that share phenotypes with ZNF837: view

Animal Model Products

CRISPR Products

miRNA for ZNF837 Gene

miRTarBase miRNAs that target ZNF837

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF837 Gene

Localization for ZNF837 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF837 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF837 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF837 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF837: view

Pathways & Interactions for ZNF837 Gene

SuperPathways for ZNF837 Gene

No Data Available

Interacting Proteins for ZNF837 Gene

Gene Ontology (GO) - Biological Process for ZNF837 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF837: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF837 Gene

Drugs & Compounds for ZNF837 Gene

No Compound Related Data Available

Transcripts for ZNF837 Gene

mRNA/cDNA for ZNF837 Gene

Unigene Clusters for ZNF837 Gene

Zinc finger protein 837:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF837 Gene

ExUns: 1a · 1b ^ 2a · 2b
SP1:
SP2: -

Relevant External Links for ZNF837 Gene

GeneLoc Exon Structure for
ZNF837
ECgene alternative splicing isoforms for
ZNF837

Expression for ZNF837 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF837 Gene

Protein differential expression in normal tissues from HIPED for ZNF837 Gene

This gene is overexpressed in Lung (41.0) and Pancreatic juice (28.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF837 Gene



Protein tissue co-expression partners for ZNF837 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF837 Gene:

ZNF837

SOURCE GeneReport for Unigene cluster for ZNF837 Gene:

Hs.222236
genes like me logo Genes that share expression patterns with ZNF837: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF837 Gene

Orthologs for ZNF837 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF837 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF837 34
  • 98.93 (n)
dog
(Canis familiaris)
Mammalia ZNF837 34 35
  • 76.97 (n)
Species where no ortholog for ZNF837 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF837 Gene

ENSEMBL:
Gene Tree for ZNF837 (if available)
TreeFam:
Gene Tree for ZNF837 (if available)

Paralogs for ZNF837 Gene

Paralogs for ZNF837 Gene

(353) SIMAP similar genes for ZNF837 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF837: view

Variants for ZNF837 Gene

Sequence variations from dbSNP and Humsavar for ZNF837 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000096586 -- 58,381,908(+) TGGTC(A/T)GGAAC upstream-variant-2KB
rs1000539931 -- 58,371,164(+) TGAAC(A/C)CGGGA intron-variant, upstream-variant-2KB
rs1000550874 -- 58,381,168(+) GAAAC(A/C)GAGGC upstream-variant-2KB
rs1000596390 -- 58,376,354(+) GAGAC(C/G)ATCCT intron-variant, upstream-variant-2KB
rs1000642632 -- 58,370,328(+) ATCTC(C/T)TTATA intron-variant, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF837 Gene

Variant ID Type Subtype PubMed ID
nsv515731 CNV gain+loss 19592680
nsv817878 CNV loss 17921354
nsv833887 CNV loss 17160897
nsv833888 CNV loss 17160897

Variation tolerance for ZNF837 Gene

Gene Damage Index Score: 4.23; 62.26% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF837 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF837

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF837 Gene

Disorders for ZNF837 Gene

Relevant External Links for ZNF837

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF837

No disorders were found for ZNF837 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF837 Gene

Publications for ZNF837 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for ZNF837 Gene

Sources for ZNF837 Gene

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