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Aliases for ZNF835 Gene

Aliases for ZNF835 Gene

  • Zinc Finger Protein 835 2 3 5
  • BC37295_3 3

External Ids for ZNF835 Gene

Previous GeneCards Identifiers for ZNF835 Gene

  • GC19M061868
  • GC19M057174
  • GC19M053484

Summaries for ZNF835 Gene

GeneCards Summary for ZNF835 Gene

ZNF835 (Zinc Finger Protein 835) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity. An important paralog of this gene is ZNF497.

UniProtKB/Swiss-Prot for ZNF835 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF835 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF835 Gene

Genomics for ZNF835 Gene

GeneHancer (GH) Regulatory Elements for ZNF835 Gene

Promoters and enhancers for ZNF835 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I056671 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE 572.9 0.0 -17 0.8 AFF1 NRF1 MAX ETS1 ZKSCAN1 POLR2A ZNF143 ZFX CHD2 ZNF835 ENSG00000268352 LOC105372473 SMIM17
GH19I056594 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 58.7 +76.3 76343 1.4 HDGF PKNOX1 ZNF133 ARID4B SIN3A FEZF1 YBX1 GLI4 ZNF48 YY1 ZNF71 U2AF2 ZNF17 ZNF543 ZNF549 ZNF264 ZNF773 ENSG00000269696 ZNF550 ZFP28
GH19I056403 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 23.9 +267.6 267634 2 HDGF ARNT ARID4B SIN3A DMAP1 YY1 POLR2B ZNF766 ZNF416 ZNF207 ZNF583 ZNF582-AS1 ZNF582 ZFP28 ZNF470 ZNF471 FIZ1 ZNF460-AS1 ENSG00000269696 ZNF542P
GH19I056392 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 23.9 +278.2 278217 1.7 ARNT SIN3A ZNF2 YY1 POLR2B ZNF766 ZNF416 ZNF207 ZNF143 SP3 ZNF582-AS1 ZNF582 GC19P056396 PIR50744 FIZ1 ZNF471 ZNF542P ZNF304 ZNF470 ZNF835
GH19I057599 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 23.9 -928.3 -928254 1.5 PKNOX1 SMAD1 ARID4B SIN3A DMAP1 YY1 E2F8 ZNF207 ZNF143 KLF13 ZNF530 ZNF606 ZNF549 ZNF135 ZNF417 ZNF132 ZNF418 ZNF446 ZNF17 LOC105372482
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF835 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF835 gene promoter:

Genomic Locations for ZNF835 Gene

Genomic Locations for ZNF835 Gene
chr19:56,661,981-56,671,783
(GRCh38/hg38)
Size:
9,803 bases
Orientation:
Minus strand
chr19:57,174,020-57,183,151
(GRCh37/hg19)

Genomic View for ZNF835 Gene

Genes around ZNF835 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF835 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF835 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF835 Gene

Proteins for ZNF835 Gene

  • Protein details for ZNF835 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y2P0-ZN835_HUMAN
    Recommended name:
    Zinc finger protein 835
    Protein Accession:
    Q9Y2P0
    Secondary Accessions:
    • B7Z5Y0
    • G3V1S0

    Protein attributes for ZNF835 Gene

    Size:
    537 amino acids
    Molecular mass:
    59631 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAD23609.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for ZNF835 Gene

Post-translational modifications for ZNF835 Gene

No Post-translational modifications

Other Protein References for ZNF835 Gene

No data available for DME Specific Peptides for ZNF835 Gene

Domains & Families for ZNF835 Gene

Gene Families for ZNF835 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF835 Gene

Suggested Antigen Peptide Sequences for ZNF835 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9Y2P0

UniProtKB/Swiss-Prot:

ZN835_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF835: view

Function for ZNF835 Gene

Molecular function for ZNF835 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF835 Gene

Gene Ontology (GO) - Molecular Function for ZNF835 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF835: view
genes like me logo Genes that share phenotypes with ZNF835: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF835 Gene

Localization for ZNF835 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF835 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF835 gene
Compartment Confidence
nucleus 5

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF835 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF835: view

Pathways & Interactions for ZNF835 Gene

SuperPathways for ZNF835 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF835 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF835: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF835 Gene

Drugs & Compounds for ZNF835 Gene

No Compound Related Data Available

Transcripts for ZNF835 Gene

mRNA/cDNA for ZNF835 Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF835 Gene

Zinc finger protein 835:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF835 Gene

No ASD Table

Relevant External Links for ZNF835 Gene

GeneLoc Exon Structure for
ZNF835
ECgene alternative splicing isoforms for
ZNF835

Expression for ZNF835 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF835 Gene

Protein differential expression in normal tissues from HIPED for ZNF835 Gene

This gene is overexpressed in Rectum (24.7), Urinary Bladder (20.2), and Adrenal (12.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF835 Gene



Protein tissue co-expression partners for ZNF835 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF835 Gene:

ZNF835

SOURCE GeneReport for Unigene cluster for ZNF835 Gene:

Hs.458438

Evidence on tissue expression from TISSUES for ZNF835 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with ZNF835: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF835 Gene

Orthologs for ZNF835 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF835 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF835 33 34
  • 99.57 (n)
dog
(Canis familiaris)
Mammalia ZNF835 33 34
  • 81.47 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 39 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 34
  • 35 (a)
ManyToMany
-- 34
  • 34 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 35 (a)
ManyToMany
chicken
(Gallus gallus)
Aves -- 34
  • 36 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 26 (a)
ManyToMany
Species where no ortholog for ZNF835 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF835 Gene

ENSEMBL:
Gene Tree for ZNF835 (if available)
TreeFam:
Gene Tree for ZNF835 (if available)

Paralogs for ZNF835 Gene

Paralogs for ZNF835 Gene

(500) SIMAP similar genes for ZNF835 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF835: view

Variants for ZNF835 Gene

Sequence variations from dbSNP and Humsavar for ZNF835 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000052771 -- 56,672,060(-) G/A upstream_transcript_variant
rs1000287737 -- 56,667,135(-) G/C intron_variant
rs1000666060 -- 56,670,948(-) C/T intron_variant
rs1000710102 -- 56,663,193(-) C/T 3_prime_UTR_variant
rs1000889838 -- 56,668,085(-) C/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF835 Gene

Variant ID Type Subtype PubMed ID
dgv546e201 CNV deletion 23290073
esv22638 CNV loss 19812545
esv2719042 CNV deletion 23290073
esv2719043 CNV deletion 23290073
esv2719045 CNV deletion 23290073
esv2741485 CNV deletion 23290073
esv3644873 CNV gain 21293372
nsv1055357 CNV gain 25217958
nsv1110730 CNV insertion 24896259
nsv1120365 CNV tandem duplication 24896259
nsv580388 CNV loss 21841781
nsv952152 CNV deletion 24416366

Variation tolerance for ZNF835 Gene

Residual Variation Intolerance Score: 49.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.15; 92.33% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF835 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF835

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF835 Gene

Disorders for ZNF835 Gene

Additional Disease Information for ZNF835

No disorders were found for ZNF835 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF835 Gene

Publications for ZNF835 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 58

Products for ZNF835 Gene

Sources for ZNF835 Gene

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