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Aliases for ZNF835 Gene

Aliases for ZNF835 Gene

  • Zinc Finger Protein 835 2 3 5
  • BC37295_3 3

External Ids for ZNF835 Gene

Previous GeneCards Identifiers for ZNF835 Gene

  • GC19M061868
  • GC19M057174
  • GC19M053484

Summaries for ZNF835 Gene

GeneCards Summary for ZNF835 Gene

ZNF835 (Zinc Finger Protein 835) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF568.

UniProtKB/Swiss-Prot for ZNF835 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF835 Gene

Genomics for ZNF835 Gene

Regulatory Elements for ZNF835 Gene

Enhancers for ZNF835 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F056671 0.6 ENCODE 22.9 +0.0 35 0.6 POLR2A HCFC1 NRF1 ZNF143 ETS1 ZKSCAN1 ZNF835 SMIM17
GH19F056660 0.8 Ensembl 13.1 +10.9 10883 0.2 KLF1 SAP130 ZNF2 ZNF335 ZNF366 POLR2A PRDM10 ZNF600 KLF8 ZBTB20 ZNF835 ZNF667 ZNF667-AS1 SMIM17
GH19F056836 1.4 FANTOM5 ENCODE 4.2 -168.0 -168047 6.4 PKNOX1 ATF1 CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZNF48 YY1 PEG3 ZNF805 ZNF471 SMIM17 ZIM2 ZNF667 ZNF835 ZNF470 ZNF583 ZFP28
GH19F056507 1.2 FANTOM5 ENCODE 3.7 +163.6 163610 2.1 ZNF76 SIN3A YY1 ZNF121 GLIS2 ZNF366 KLF7 ZNF391 EGR2 ZNF280D ENSG00000269696 ZNF667 ZNF471 ZNF583 ZNF835 ZNF470 ZFP28 ZNF71 SMIM17 ZNF582
GH19F056983 0.8 FANTOM5 ENCODE 1.6 -311.9 -311860 0.7 ZNF146 ZNF280D RFX1 RFX3 ZMYM3 AURKC USP29 ZNF471 ZNF835 ZNF772 GC19P057027 ENSG00000269786
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF835 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF835 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001819018 -17 1200 POLR2A HCFC1 NRF1 ZNF143 ETS1 ZKSCAN1

Genomic Location for ZNF835 Gene

Chromosome:
19
Start:
56,661,981 bp from pter
End:
56,671,783 bp from pter
Size:
9,803 bases
Orientation:
Minus strand

Genomic View for ZNF835 Gene

Genes around ZNF835 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF835 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF835 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF835 Gene

Proteins for ZNF835 Gene

  • Protein details for ZNF835 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y2P0-ZN835_HUMAN
    Recommended name:
    Zinc finger protein 835
    Protein Accession:
    Q9Y2P0
    Secondary Accessions:
    • B7Z5Y0
    • G3V1S0

    Protein attributes for ZNF835 Gene

    Size:
    537 amino acids
    Molecular mass:
    59631 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAD23609.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for ZNF835 Gene

Post-translational modifications for ZNF835 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF835 Gene

No data available for DME Specific Peptides for ZNF835 Gene

Domains & Families for ZNF835 Gene

Gene Families for ZNF835 Gene

Protein Domains for ZNF835 Gene

Suggested Antigen Peptide Sequences for ZNF835 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9Y2P0

UniProtKB/Swiss-Prot:

ZN835_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 14 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 14 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF835: view

Function for ZNF835 Gene

Molecular function for ZNF835 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF835 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF835: view
genes like me logo Genes that share phenotypes with ZNF835: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF835 Gene

Localization for ZNF835 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF835 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF835 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF835 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF835: view

Pathways & Interactions for ZNF835 Gene

SuperPathways for ZNF835 Gene

No Data Available

Interacting Proteins for ZNF835 Gene

Gene Ontology (GO) - Biological Process for ZNF835 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
genes like me logo Genes that share ontologies with ZNF835: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF835 Gene

Transcripts for ZNF835 Gene

mRNA/cDNA for ZNF835 Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF835 Gene

Zinc finger protein 835:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF835 Gene

No ASD Table

Relevant External Links for ZNF835 Gene

GeneLoc Exon Structure for
ZNF835
ECgene alternative splicing isoforms for
ZNF835

Expression for ZNF835 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF835 Gene

Protein differential expression in normal tissues from HIPED for ZNF835 Gene

This gene is overexpressed in Rectum (24.7), Urinary Bladder (20.2), and Adrenal (12.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF835 Gene



Protein tissue co-expression partners for ZNF835 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF835 Gene:

ZNF835

SOURCE GeneReport for Unigene cluster for ZNF835 Gene:

Hs.458438
genes like me logo Genes that share expression patterns with ZNF835: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF835 Gene

Orthologs for ZNF835 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF835 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF835 34 35
  • 99.57 (n)
dog
(Canis familiaris)
Mammalia ZNF835 34 35
  • 81.47 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 39 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 35 (a)
ManyToMany
-- 35
  • 34 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 35 (a)
ManyToMany
chicken
(Gallus gallus)
Aves -- 35
  • 36 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 26 (a)
ManyToMany
Species where no ortholog for ZNF835 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF835 Gene

ENSEMBL:
Gene Tree for ZNF835 (if available)
TreeFam:
Gene Tree for ZNF835 (if available)

Paralogs for ZNF835 Gene

(500) SIMAP similar genes for ZNF835 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF835: view

Variants for ZNF835 Gene

Sequence variations from dbSNP and Humsavar for ZNF835 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10084136 -- 56,673,377(+) CCCCC(C/G)CTCTC intron-variant, upstream-variant-2KB
rs10084151 -- 56,670,836(+) CACGG(C/T)GGCAC intron-variant, upstream-variant-2KB
rs10084152 -- 56,670,847(+) ACCCA(C/G)ACATG intron-variant, upstream-variant-2KB
rs10084155 -- 56,671,181(+) CTCAG(G/T)GACGG intron-variant, upstream-variant-2KB
rs10084156 -- 56,671,237(+) AGCAG(C/G)TGCAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF835 Gene

Variant ID Type Subtype PubMed ID
nsv952152 CNV deletion 24416366
nsv580388 CNV loss 21841781
nsv1120365 CNV tandem duplication 24896259
nsv1110730 CNV insertion 24896259
nsv1055357 CNV gain 25217958
esv3644873 CNV gain 21293372
esv2741485 CNV deletion 23290073
esv2719045 CNV deletion 23290073
esv2719043 CNV deletion 23290073
esv2719042 CNV deletion 23290073
esv22638 CNV loss 19812545
dgv546e201 CNV deletion 23290073

Variation tolerance for ZNF835 Gene

Residual Variation Intolerance Score: 49.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.15; 92.33% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF835 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF835

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF835 Gene

Disorders for ZNF835 Gene

Relevant External Links for ZNF835

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF835

No disorders were found for ZNF835 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF835 Gene

Publications for ZNF835 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64

Products for ZNF835 Gene

Sources for ZNF835 Gene

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