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Aliases for ZNF831 Gene

Aliases for ZNF831 Gene

  • Zinc Finger Protein 831 2 3 5
  • C20orf174 3 4
  • Chromosome 20 Open Reading Frame 174 2
  • DJ492J12.1 3

External Ids for ZNF831 Gene

Previous HGNC Symbols for ZNF831 Gene

  • C20orf174

Previous GeneCards Identifiers for ZNF831 Gene

  • GC20P057200
  • GC20P057766
  • GC20P054553

Summaries for ZNF831 Gene

GeneCards Summary for ZNF831 Gene

ZNF831 (Zinc Finger Protein 831) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is HIVEP1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF831 Gene

Genomics for ZNF831 Gene

Regulatory Elements for ZNF831 Gene

Enhancers for ZNF831 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ZNF831 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF831 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF831 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF831 Gene

Chromosome:
20
Start:
59,123,381 bp from pter
End:
59,259,113 bp from pter
Size:
135,733 bases
Orientation:
Plus strand

Genomic View for ZNF831 Gene

Genes around ZNF831 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF831 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF831 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF831 Gene

Proteins for ZNF831 Gene

  • Protein details for ZNF831 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JPB2-ZN831_HUMAN
    Recommended name:
    Zinc finger protein 831
    Protein Accession:
    Q5JPB2
    Secondary Accessions:
    • Q5TDR4
    • Q8TCP0

    Protein attributes for ZNF831 Gene

    Size:
    1677 amino acids
    Molecular mass:
    177949 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI46154.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF831 Gene

Post-translational modifications for ZNF831 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF831 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF831 Gene

Domains & Families for ZNF831 Gene

Protein Domains for ZNF831 Gene

Suggested Antigen Peptide Sequences for ZNF831 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5JPB2

UniProtKB/Swiss-Prot:

ZN831_HUMAN :
  • Contains 2 C2H2-type zinc fingers.
Similarity:
  • Contains 2 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF831: view

No data available for Gene Families for ZNF831 Gene

Function for ZNF831 Gene

Gene Ontology (GO) - Molecular Function for ZNF831 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0043565 sequence-specific DNA binding IBA --
GO:0044212 transcription regulatory region DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF831: view
genes like me logo Genes that share phenotypes with ZNF831: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF831 Gene

Localization for ZNF831 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF831 Gene COMPARTMENTS Subcellular localization image for ZNF831 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF831 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZNF831: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ZNF831 Gene

Pathways & Interactions for ZNF831 Gene

SuperPathways for ZNF831 Gene

No Data Available

Interacting Proteins for ZNF831 Gene

Gene Ontology (GO) - Biological Process for ZNF831 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IBA --
GO:0006366 transcription from RNA polymerase II promoter IBA --
GO:0007165 signal transduction IBA --
GO:0007275 multicellular organism development IBA --
genes like me logo Genes that share ontologies with ZNF831: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF831 Gene

Drugs & Compounds for ZNF831 Gene

No Compound Related Data Available

Transcripts for ZNF831 Gene

mRNA/cDNA for ZNF831 Gene

(12) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF831 Gene

Zinc finger protein 831:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF831 Gene

No ASD Table

Relevant External Links for ZNF831 Gene

GeneLoc Exon Structure for
ZNF831
ECgene alternative splicing isoforms for
ZNF831

Expression for ZNF831 Gene

mRNA expression in normal human tissues for ZNF831 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF831 Gene

This gene is overexpressed in Whole Blood (x7.0) and Spleen (x5.5).

Protein differential expression in normal tissues from HIPED for ZNF831 Gene

This gene is overexpressed in Heart (37.9) and Tlymphocyte (28.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF831 Gene



Protein tissue co-expression partners for ZNF831 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF831 Gene:

ZNF831

SOURCE GeneReport for Unigene cluster for ZNF831 Gene:

Hs.473204
genes like me logo Genes that share expression patterns with ZNF831: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF831 Gene

Orthologs for ZNF831 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF831 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC100140850 34
  • 73.64 (n)
  • 61.7 (a)
ZNF831 35
  • 60 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF831 34
  • 76.01 (n)
  • 67.11 (a)
ZNF831 35
  • 63 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp831 34
  • 69.29 (n)
  • 58.34 (a)
Zfp831 16
Zfp831 35
  • 58 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF831 34
  • 99.3 (n)
  • 98.81 (a)
ZNF831 35
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1565819 34
  • 69.01 (n)
  • 57.84 (a)
oppossum
(Monodelphis domestica)
Mammalia ZNF831 35
  • 34 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 7 (a)
OneToMany
-- 35
  • 20 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia ZNF831 35
  • 46 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii znf831 35
  • 22 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta shn 35
  • 9 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea sma-9 35
  • 8 (a)
OneToMany
Species where no ortholog for ZNF831 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZNF831 Gene

ENSEMBL:
Gene Tree for ZNF831 (if available)
TreeFam:
Gene Tree for ZNF831 (if available)

Paralogs for ZNF831 Gene

Paralogs for ZNF831 Gene

(1) SIMAP similar genes for ZNF831 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZNF831 Gene

genes like me logo Genes that share paralogs with ZNF831: view

Variants for ZNF831 Gene

Sequence variations from dbSNP and Humsavar for ZNF831 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs181984 - 59,193,552(-) CCCAC(C/G)TGGGG reference, missense
rs259956 - 59,254,246(+) CTGAA(A/C/T)CACGA reference, missense
rs201549554 - 59,254,553(+) GAAAC(A/G)TCAGG reference, missense
rs140844 -- 59,152,312(+) GGAGT(-/GGGA)GGGAG intron-variant
rs171042 -- 59,129,324(+) cccaa(C/T)gctaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF831 Gene

Variant ID Type Subtype PubMed ID
dgv2275n106 CNV deletion 24896259
esv2223494 CNV deletion 18987734
esv2722629 CNV deletion 23290073
esv2722630 CNV deletion 23290073
esv3557276 CNV deletion 23714750
esv8268 CNV loss 19470904
nsv1073072 CNV deletion 25765185
nsv178602 CNV deletion 16902084
nsv3431 CNV insertion 18451855
nsv523738 CNV loss 19592680
nsv819120 CNV loss 19587683
nsv834020 CNV loss 17160897
nsv834021 CNV gain 17160897

Variation tolerance for ZNF831 Gene

Residual Variation Intolerance Score: 82.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.34; 63.14% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF831 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF831

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF831 Gene

Disorders for ZNF831 Gene

Relevant External Links for ZNF831

Genetic Association Database (GAD)
ZNF831
Human Genome Epidemiology (HuGE) Navigator
ZNF831
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF831

No disorders were found for ZNF831 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF831 Gene

Publications for ZNF831 Gene

  1. Genomewide association study of movement-related adverse antipsychotic effects. (PMID: 19875103) Aberg K. … van den Oord E.J. (Biol. Psychiatry 2010) 3 46 65
  2. Genome-wide association study of blood pressure and hypertension. (PMID: 19430479) Levy D. … van Duijn C.M. (Nat. Genet. 2009) 3 46 65
  3. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4 65
  4. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. (PMID: 23128233) Jostins L. … Cho J.H. (Nature 2012) 3 65
  5. Diagnostic exome sequencing in persons with severe intellectual disability. (PMID: 23033978) de Ligt J. … Vissers L.E. (N. Engl. J. Med. 2012) 4 65

Products for ZNF831 Gene

Sources for ZNF831 Gene

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