ZNF830 Gene
protein-coding GIFtS: 44
GCID: GC17P033288
|
|
zinc finger protein 830(Previous name: coiled-coil domain containing 16 )
(Previous symbol: CCDC16)
| |
Aliases
for ZNF830 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 8301 2 | | Coiled-Coil Domain-Containing Protein 162 3 | | CCDC161 2 3 | | MGC203981 | | OMCG11 2 | | Hypothetical Protein MGC203982 | | SEL131 2 | | Sel-13 Suppressor Of Lin-12 Homolog2 | | Coiled-Coil Domain Containing 161 2 | | |
Export aliases for ZNF830 gene to outside databasesPrevious GC identifers: GC17P030315 GC17P029474 |
Summaries
for ZNF830 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN830_HUMAN, Q96NB3Function: May act as a regulator of the cell cycle in embryos by participating in control of M phase (By similarity)
|
Genomic Views
for ZNF830 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010799.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF830 gene promoter:
Elk-1 AML1a p53 FOXJ2 (long isoform) STAT3 FOXJ2 XBP-1 CUTL1 LyF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF830
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF830 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q12 Ensembl cytogenetic band: 17q12 HGNC cytogenetic band: 17q12ZNF830 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P033288: view genomic region
(about GC identifiers)
Start:
|
33,288,549 bp from pter |
End:
|
33,290,205 bp from pter |
Size:
|
1,657 bases |
Orientation:
|
plus strand |
|
Proteins
for ZNF830 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN830_HUMAN, Q96NB3 (See
protein sequence)Recommended Name: Zinc finger protein 830 Size: 372 amino acids; 41999 Da
Subcellular location: Nucleus (By similarity). Note=Excluded from nucleolus (By similarity)
Secondary accessions: Q96F60 Q96GZ5 Q9BU38Explore the universe of human proteins at neXtProt for ZNF830: NX_Q96NB3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96NB3
ZNF830 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_443089.3
ENSEMBL proteins: ENSP00000463839 ENSP00000354518
Human Recombinant Protein Products for ZNF830:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ZNF830 for ontologies About GeneDecksing
ZNF830 Antibody Products:
Assay Products for ZNF830: |
Protein
Domains /
Families
for ZNF830 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF830 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96NB3ProtoNet protein and cluster: Q96NB3 UniProtKB/Swiss-Prot: ZN830_HUMAN, Q96NB3Similarity: Contains 1 C2H2-type zinc finger |
Function
for ZNF830 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ZN830_HUMAN, Q96NB3Function: May act as a regulator of the cell cycle in embryos by participating in control of M phase (By similarity) Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0046872 | metal ion binding |
IEA | -- |
ZNF830 for ontologies About GeneDecksing
Phenotypes:
2 GenomeRNAi human phenotypes for ZNF830:
5 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Zfp830):
ZNF830 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-outs for ZNF830: Zfp830tm2.2Cota Zfp830tm1Cota
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF830 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF830
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF830 (NM_052857) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF830 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF830 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF830 |
|
Pathways & Interactions
for ZNF830 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF830
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/11 Interacting proteins for ZNF830 (Q96NB32 ENSP000003545184) via UniProtKB, MINT, STRING, and/or I2D (see all 11)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
ZNF830 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF830 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF830
Search CenterWatch for drugs/clinical trials and news about ZNF830 / ZN830
|
Transcripts
for ZNF830 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF830 gene: NM_052857.3 Unigene Cluster for ZNF830: Zinc finger protein 830 Hs.413678 [show with all ESTs]Unigene Representative Sequence: NM_0528572 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000578339 ENST00000361952(uc002hih.4)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF830 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF830
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF830 (NM_052857) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF830 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF830 |
Additional cDNA sequence: AK055707.1 AK315671.1 BC002913.2 BC009044.1 BC011584.1 4 DOTS entries: DT.95374937 DT.113704 DT.75113916 DT.99953302 24/116 AceView cDNA sequences (see all 116): AI079480 AA310726 AA282045 BU687023 AI566327 BX092810 AA913794 NM_052857 AA909511 AI082230 AI086137 AI914296 BC009044 BE043032 AW803474 AI217360 CR617791 CR620924 CR606415 AA806462 AL697685 AI275024 BX098787 BC002913
GeneLoc Exon Structure
|
Expression
for ZNF830 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF830 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTTTGAGGT
About this image
See ZNF830 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF830
SOURCE GeneReport for Unigene cluster: Hs.413678
SABiosciences Custom PCR Arrays for ZNF830
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF830
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZNF830 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF830 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF830 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF830 |
Orthologs
for ZNF830 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ZNF830 gene from 9/24 species (see all 24) About this table
ENSEMBL Gene Tree for ZNF830 (if available)
TreeFam Gene Tree for ZNF830 (if available) |
Paralogs
for ZNF830 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ZNF830 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF830 (33288549 - 33290205 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF830: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF830 |
|
Disorders
/ Diseases
for ZNF830 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF830 for disorders About GeneDecksing
2  diseases for ZNF830: About MalaCardsxeroderma pigmentosum cockayne syndrome
1 disease from the University of Copenhagen DISEASES database for ZNF830:Cockayne syndrome Human Genome Epidemiology (HuGE) Navigator: ZNF830 (1 document)
Export disorders for ZNF830 gene to outside databases
|
Publications
for ZNF830 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF830 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with ZNF830) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- Association between genetic variants in VEGF, ERCC3 a nd occupational benzene haematotoxicity. (PubMed id 19773279)1 Hosgood H.D....Lan Q. (2009)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
|
External Searches for ZNF830 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF830 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF830 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF830 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF830 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF830 gene:
Search GeneIP for patents involving ZNF830
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF830 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF830 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF830 | | | OriGene Protein Over-expression Lysate for ZNF830 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF830 | | OriGene 3'-UTR Clone for ZNF830 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF830 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF830 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF830 | | OriGene Custom Protein Services for ZNF830 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF830 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF830 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF830 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF830 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF830 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF830 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ZNF830 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ZNF830 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF830 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for ZNF830 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF830 |
| |  | |
|
|
|
