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Aliases for ZNF83 Gene

Aliases for ZNF83 Gene

  • Zinc Finger Protein 83 2 3
  • Zinc Finger Protein 816B 2 3 4
  • Zinc Finger Protein HPF1 3 4
  • ZNF816B 3 4
  • Zinc Finger Protein 83 (HPF1) 2
  • HPF1 3

External Ids for ZNF83 Gene

Previous HGNC Symbols for ZNF83 Gene

  • ZNF816B

Previous GeneCards Identifiers for ZNF83 Gene

  • GC19M053746
  • GC19M053476
  • GC19M057773
  • GC19M057807
  • GC19M057189
  • GC19M053115
  • GC19M049446

Summaries for ZNF83 Gene

GeneCards Summary for ZNF83 Gene

ZNF83 (Zinc Finger Protein 83) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF860.

UniProtKB/Swiss-Prot for ZNF83 Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZNF83 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF83 Gene

Genomics for ZNF83 Gene

Regulatory Elements for ZNF83 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF83 Gene

Chromosome:
19
Start:
52,594,060 bp from pter
End:
52,690,581 bp from pter
Size:
96,522 bases
Orientation:
Minus strand

Genomic View for ZNF83 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF83 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF83 Gene

Proteins for ZNF83 Gene

  • Protein details for ZNF83 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P51522-ZNF83_HUMAN
    Recommended name:
    Zinc finger protein 83
    Protein Accession:
    P51522
    Secondary Accessions:
    • A8MT75
    • Q3ZCX0
    • Q6PI08

    Protein attributes for ZNF83 Gene

    Size:
    516 amino acids
    Molecular mass:
    59710 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF83 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF83 Gene

Proteomics data for ZNF83 Gene at MOPED

Post-translational modifications for ZNF83 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for ZNF83 Gene

Domains & Families for ZNF83 Gene

Gene Families for ZNF83 Gene

Protein Domains for ZNF83 Gene

Suggested Antigen Peptide Sequences for ZNF83 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P51522

UniProtKB/Swiss-Prot:

ZNF83_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 15 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 15 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF83: view

Function for ZNF83 Gene

Molecular function for ZNF83 Gene

GENATLAS Biochemistry:
zinc finger protein 83 (C2H2 type)
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF83 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0005515 protein binding IPI 16237761
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF83: view
genes like me logo Genes that share phenotypes with ZNF83: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF83 Gene

Localization for ZNF83 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF83 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF83 Gene COMPARTMENTS Subcellular localization image for ZNF83 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF83 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF83: view

Pathways & Interactions for ZNF83 Gene

SuperPathways for ZNF83 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF83 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF83: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF83 Gene

Drugs & Compounds for ZNF83 Gene

No Compound Related Data Available

Transcripts for ZNF83 Gene

Unigene Clusters for ZNF83 Gene

Zinc finger protein 83:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF83 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c · 5d
SP1: - -
SP2:
SP3: - - - -
SP4: - - -

Relevant External Links for ZNF83 Gene

GeneLoc Exon Structure for
ZNF83
ECgene alternative splicing isoforms for
ZNF83

Expression for ZNF83 Gene

mRNA expression in normal human tissues for ZNF83 Gene

SOURCE GeneReport for Unigene cluster for ZNF83 Gene Hs.467210

genes like me logo Genes that share expression patterns with ZNF83: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF83 Gene

Orthologs for ZNF83 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF83 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 41 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 43 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia ZNF83 36
  • 57 (a)
OneToOne
Species with no ortholog for ZNF83:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF83 Gene

ENSEMBL:
Gene Tree for ZNF83 (if available)
TreeFam:
Gene Tree for ZNF83 (if available)

Paralogs for ZNF83 Gene

Pseudogenes.org Pseudogenes for ZNF83 Gene

genes like me logo Genes that share paralogs with ZNF83: view

Variants for ZNF83 Gene

Sequence variations from dbSNP and Humsavar for ZNF83 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs170671 -- 52,645,851(+) AAGAG(A/G)AAACA intron-variant
rs179321 -- 52,641,121(+) TTCCC(A/G)TTGTA intron-variant
rs189082 -- 52,646,274(+) gtgtg(A/G)tggct intron-variant
rs193039 -- 52,648,460(+) aaaaa(A/G)agaga intron-variant
rs193411 -- 52,645,109(+) GGCCT(A/G)AGGGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF83 Gene

Variant ID Type Subtype PubMed ID
esv2718786 CNV Deletion 23290073
nsv833874 CNV Loss 17160897
esv2718787 CNV Deletion 23290073
dgv3980n71 CNV Gain 21882294
dgv3981n71 CNV Gain 21882294
nsv828616 CNV Gain 20364138
nsv912311 CNV Gain 21882294
dgv3982n71 CNV Loss 21882294
nsv519070 CNV Loss 19592680
nsv527815 CNV Loss 19592680
nsv817857 CNV Gain 17921354
nsv522273 CNV Loss 19592680
esv2718792 CNV Deletion 23290073
esv2094808 CNV Deletion 18987734
esv2718793 CNV Deletion 23290073
nsv458744 CNV Gain 19166990
esv2718794 CNV Deletion 23290073
nsv509752 CNV Insertion 20534489
dgv3983n71 CNV Loss 21882294
esv2677925 CNV Deletion 23128226
esv2718796 CNV Deletion 23290073
dgv3984n71 CNV Gain 21882294

Variation tolerance for ZNF83 Gene

Residual Variation Intolerance Score: 64.84% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.51; 91.11% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF83 Gene

HapMap Linkage Disequilibrium report
ZNF83

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF83 Gene

Disorders for ZNF83 Gene

Relevant External Links for ZNF83

Genetic Association Database (GAD)
ZNF83
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF83
genes like me logo Genes that share disorders with ZNF83: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF83 Gene

Publications for ZNF83 Gene

  1. Assignment of the human ZNF83 (HPF1) zinc finger gene to chromosome 19q13.3-q13.4. (PMID: 8088807) Marine J.C. … Szpirer C. (Genomics 1994) 2 67
  2. A human MAP kinase interactome. (PMID: 20936779) Bandyopadhyay S. … Ideker T. (Nat. Methods 2010) 67
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67
  4. Identification of genes related to Parkinson's disease using expressed sequence tags. (PMID: 17213182) Kim J.M. … Kim N.S. (DNA Res. 2006) 67
  5. Screening of hepatocyte proteins binding to F protein of hepatitis C virus by yeast two-hybrid system. (PMID: 16237761) Huang Y.P. … Shao Q. (World J. Gastroenterol. 2005) 67

Products for ZNF83 Gene

Sources for ZNF83 Gene

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