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Aliases for ZNF827 Gene

Aliases for ZNF827 Gene

  • Zinc Finger Protein 827 2 3 5

External Ids for ZNF827 Gene

Previous GeneCards Identifiers for ZNF827 Gene

  • GC04M146902
  • GC04M146681
  • GC04M142410

Summaries for ZNF827 Gene

GeneCards Summary for ZNF827 Gene

ZNF827 (Zinc Finger Protein 827) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.

UniProtKB/Swiss-Prot for ZNF827 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF827 Gene

Genomics for ZNF827 Gene

Regulatory Elements for ZNF827 Gene

Promoters for ZNF827 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF827 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF827 Gene

Chromosome:
4
Start:
145,757,627 bp from pter
End:
145,938,635 bp from pter
Size:
181,009 bases
Orientation:
Minus strand

Genomic View for ZNF827 Gene

Genes around ZNF827 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF827 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF827 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF827 Gene

Proteins for ZNF827 Gene

  • Protein details for ZNF827 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q17R98-ZN827_HUMAN
    Recommended name:
    Zinc finger protein 827
    Protein Accession:
    Q17R98
    Secondary Accessions:
    • B7ZL52
    • Q7Z4S7
    • Q8N279

    Protein attributes for ZNF827 Gene

    Size:
    1081 amino acids
    Molecular mass:
    119165 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF827 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF827 Gene

Proteomics data for ZNF827 Gene at MOPED

Post-translational modifications for ZNF827 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF827 Gene

No data available for DME Specific Peptides for ZNF827 Gene

Domains & Families for ZNF827 Gene

Gene Families for ZNF827 Gene

Protein Domains for ZNF827 Gene

Suggested Antigen Peptide Sequences for ZNF827 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q17R98

UniProtKB/Swiss-Prot:

ZN827_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF827: view

Function for ZNF827 Gene

Molecular function for ZNF827 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF827 Gene

genes like me logo Genes that share phenotypes with ZNF827: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF827 Gene

Localization for ZNF827 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF827 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF827 Gene COMPARTMENTS Subcellular localization image for ZNF827 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF827 Gene

Pathways & Interactions for ZNF827 Gene

SuperPathways for ZNF827 Gene

No Data Available

Interacting Proteins for ZNF827 Gene

Gene Ontology (GO) - Biological Process for ZNF827 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF827: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF827 Gene

Drugs & Compounds for ZNF827 Gene

No Compound Related Data Available

Transcripts for ZNF827 Gene

Unigene Clusters for ZNF827 Gene

Zinc finger protein 827:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF827 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b · 15c ^ 16 ^ 17a · 17b
SP1: - - - - -
SP2: - - -
SP3: - - -
SP4: - -
SP5:
SP6: - -
SP7:
SP8:

Relevant External Links for ZNF827 Gene

GeneLoc Exon Structure for
ZNF827
ECgene alternative splicing isoforms for
ZNF827

Expression for ZNF827 Gene

mRNA expression in normal human tissues for ZNF827 Gene

Protein differential expression in normal tissues from HIPED for ZNF827 Gene

This gene is overexpressed in Liver (41.8), Urine (19.5), and Lung (6.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF827 Gene



SOURCE GeneReport for Unigene cluster for ZNF827 Gene Hs.633543

genes like me logo Genes that share expression patterns with ZNF827: view

Protein tissue co-expression partners for ZNF827 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF827 Gene

Orthologs for ZNF827 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF827 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF827 35
  • 91.57 (n)
  • 95.07 (a)
ZNF827 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF827 35
  • 93.85 (n)
  • 96.83 (a)
ZNF827 36
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp827 35
  • 89.4 (n)
  • 93.94 (a)
Zfp827 16
Zfp827 36
  • 93 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF827 35
  • 99.78 (n)
  • 99.81 (a)
ZNF827 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp827 35
  • 89.02 (n)
  • 93.28 (a)
oppossum
(Monodelphis domestica)
Mammalia ZNF827 36
  • 89 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF827 36
  • 78 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF827 35
  • 79.89 (n)
  • 82.03 (a)
ZNF827 36
  • 80 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF827 36
  • 72 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia znf827 35
  • 71.04 (n)
  • 72.15 (a)
zebrafish
(Danio rerio)
Actinopterygii znf827 35
  • 61.99 (n)
  • 60.81 (a)
znf827 36
  • 50 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG11966 36
  • 8 (a)
OneToMany
ken 36
  • 13 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea blmp-1 36
  • 12 (a)
OneToOne
Species with no ortholog for ZNF827:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ZNF827 Gene

ENSEMBL:
Gene Tree for ZNF827 (if available)
TreeFam:
Gene Tree for ZNF827 (if available)

Paralogs for ZNF827 Gene

genes like me logo Genes that share paralogs with ZNF827: view

No data available for Paralogs for ZNF827 Gene

Variants for ZNF827 Gene

Sequence variations from dbSNP and Humsavar for ZNF827 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs988163 -- 145,843,731(-) ATCAG(A/G)CAACA intron-variant
rs925136 -- 145,867,673(+) ACTAA(A/G)TATCC intron-variant
rs949765 -- 145,813,368(-) aaata(A/C/G/T)aacaa intron-variant
rs1001198 -- 145,813,516(-) AGGGG(A/G)TACAT intron-variant
rs878451 -- 145,816,831(+) AGGAG(A/T)AGATA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF827 Gene

Variant ID Type Subtype PubMed ID
esv1009413 CNV Insertion 20482838
esv1522611 CNV Insertion 17803354
esv2544769 CNV Deletion 19546169
nsv830106 CNV Gain 17160897

Variation tolerance for ZNF827 Gene

Residual Variation Intolerance Score: 5.66% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.54; 29.83% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF827 Gene

HapMap Linkage Disequilibrium report
ZNF827

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF827 Gene

Disorders for ZNF827 Gene

Relevant External Links for ZNF827

Genetic Association Database (GAD)
ZNF827
Human Genome Epidemiology (HuGE) Navigator
ZNF827
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF827

No disorders were found for ZNF827 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF827 Gene

Publications for ZNF827 Gene

  1. NuRD-ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination. (PMID: 25150861) Conomos D. … Pickett H.A. (Nat. Struct. Mol. Biol. 2014) 2 3 67
  2. GWAS of dental caries patterns in the permanent dentition. (PMID: 23064961) Shaffer J.R. … Marazita M.L. (J. Dent. Res. 2013) 3
  3. The functional interactome landscape of the human histone deacetylase family. (PMID: 23752268) Joshi P. … Cristea I.M. (Mol. Syst. Biol. 2013) 3
  4. A genome-wide association study of behavioral disinhibition. (PMID: 23942779) McGue M. … Iacono W.G. (Behav. Genet. 2013) 3
  5. Protein phosphatase 1I+ interacting proteins in the human brain. (PMID: 22321011) Esteves S.L. … da Cruz e Silva E.F. (OMICS 2012) 3

Products for ZNF827 Gene

Sources for ZNF827 Gene

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