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Aliases for ZNF827 Gene

Aliases for ZNF827 Gene

  • Zinc Finger Protein 827 2 3

External Ids for ZNF827 Gene

Summaries for ZNF827 Gene

GeneCards Summary for ZNF827 Gene

ZNF827 (Zinc Finger Protein 827) is a Protein Coding gene. An important paralog of this gene is PRDM1.

UniProtKB/Swiss-Prot for ZNF827 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF827 Gene

Genomics for ZNF827 Gene

Genomic Location for ZNF827 Gene

Start:
145,757,627 bp from pter
End:
145,938,635 bp from pter
Size:
181,009 bases
Orientation:
Minus strand

Genomic View for ZNF827 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF827 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF827 Gene

Regulatory Elements for ZNF827 Gene

Proteins for ZNF827 Gene

  • Protein details for ZNF827 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q17R98-ZN827_HUMAN
    Recommended name:
    Zinc finger protein 827
    Protein Accession:
    Q17R98
    Secondary Accessions:
    • B7ZL52
    • Q7Z4S7
    • Q8N279

    Protein attributes for ZNF827 Gene

    Size:
    1081 amino acids
    Molecular mass:
    119165 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF827 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF827 Gene

Proteomics data for ZNF827 Gene at MOPED

Post-translational modifications for ZNF827 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF827 Gene

No data available for DME Specific Peptides for ZNF827 Gene

Domains for ZNF827 Gene

Gene Families for ZNF827 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF827 Gene

UniProtKB/Swiss-Prot:

ZN827_HUMAN
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q17R98
Similarity:
  • Contains 9 C2H2-type zinc fingers.:
    • Q17R98
genes like me logo Genes that share domains with ZNF827: view

Function for ZNF827 Gene

Molecular function for ZNF827 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF827 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF827: view

miRNA for ZNF827 Gene

miRTarBase miRNAs that target ZNF827

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF827 Gene

Localization for ZNF827 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF827 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF827 Gene COMPARTMENTS Subcellular localization image for ZNF827 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF827 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF827: view

Pathways for ZNF827 Gene

SuperPathways for ZNF827 Gene

No Data Available

Interacting Proteins for ZNF827 Gene

Gene Ontology (GO) - Biological Process for ZNF827 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF827: view

No data available for Pathways by source for ZNF827 Gene

Transcripts for ZNF827 Gene

Unigene Clusters for ZNF827 Gene

Zinc finger protein 827:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF827 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b · 15c ^ 16 ^ 17a · 17b
SP1: - - - - -
SP2: - - -
SP3: - - -
SP4: - -
SP5:
SP6: - -
SP7:
SP8:

Relevant External Links for ZNF827 Gene

GeneLoc Exon Structure for
ZNF827
ECgene alternative splicing isoforms for
ZNF827

Expression for ZNF827 Gene

mRNA expression in normal human tissues for ZNF827 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF827 Gene

SOURCE GeneReport for Unigene cluster for ZNF827 Gene Hs.633543

genes like me logo Genes that share expressions with ZNF827: view

Orthologs for ZNF827 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF827 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF827 36
  • 99.78 (n)
  • 99.81 (a)
ZNF827 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF827 36
  • 91.57 (n)
  • 95.07 (a)
ZNF827 37
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF827 36
  • 93.85 (n)
  • 96.83 (a)
ZNF827 37
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp827 36
  • 89.4 (n)
  • 93.94 (a)
Zfp827 16
Zfp827 37
  • 93 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF827 37
  • 89 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF827 37
  • 78 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp827 36
  • 89.02 (n)
  • 93.28 (a)
chicken
(Gallus gallus)
Aves ZNF827 36
  • 79.89 (n)
  • 82.03 (a)
ZNF827 37
  • 80 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF827 37
  • 72 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia znf827 36
  • 71.04 (n)
  • 72.15 (a)
zebrafish
(Danio rerio)
Actinopterygii znf827 36
  • 61.99 (n)
  • 60.81 (a)
znf827 37
  • 50 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG11966 37
  • 8 (a)
OneToMany
ken 37
  • 13 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea blmp-1 37
  • 12 (a)
OneToOne
Species with no ortholog for ZNF827:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ZNF827 Gene

ENSEMBL:
Gene Tree for ZNF827 (if available)
TreeFam:
Gene Tree for ZNF827 (if available)

Paralogs for ZNF827 Gene

Paralogs for ZNF827 Gene

genes like me logo Genes that share paralogs with ZNF827: view

Variants for ZNF827 Gene

Sequence variations from dbSNP and Humsavar for ZNF827 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs878451 -- 145,816,831(+) AGGAG(A/T)AGATA intron-variant
rs925136 -- 145,867,673(+) ACTAA(A/G)TATCC intron-variant
rs949765 -- 145,813,368(-) aaata(A/C/G/T)aacaa intron-variant
rs988163 -- 145,843,731(-) ATCAG(A/G)CAACA intron-variant
rs1001198 -- 145,813,516(-) AGGGG(A/G)TACAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF827 Gene

Variant ID Type Subtype PubMed ID
esv1009413 CNV Insertion 20482838
esv1522611 CNV Insertion 17803354
esv2544769 CNV Deletion 19546169
nsv830106 CNV Gain 17160897

Relevant External Links for ZNF827 Gene

HapMap Linkage Disequilibrium report
ZNF827

Disorders for ZNF827 Gene

Relevant External Links for ZNF827

Genetic Association Database (GAD)
ZNF827
Human Genome Epidemiology (HuGE) Navigator
ZNF827
genes like me logo Genes that share disorders with ZNF827: view

No data available for UniProtKB/Swiss-Prot for ZNF827 Gene

Publications for ZNF827 Gene

  1. Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PMID: 19240061) Trynka G. … Wijmenga C. (Gut 2009) 3 49
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  3. Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits. (PMID: 21909109) Kim Y.J. … Cho Y.S. (Nat. Genet. 2011) 3 49
  4. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. (PMID: 22001757) Chambers J.C. … Kooner J.S. (Nat. Genet. 2011) 3 49
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4

Products for ZNF827 Gene

Sources for ZNF827 Gene

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