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Aliases for ZNF823 Gene

Aliases for ZNF823 Gene

  • Zinc Finger Protein 823 2 3 5
  • ZFP 36 For A Zinc Finger Protein 2 3
  • Zinc Finger Protein ZFP-36 3 4
  • HSZFP36 3
  • ZFP36 4

External Ids for ZNF823 Gene

Previous GeneCards Identifiers for ZNF823 Gene

  • GC19M011700
  • GC19M011832
  • GC19M011410

Summaries for ZNF823 Gene

GeneCards Summary for ZNF823 Gene

ZNF823 (Zinc Finger Protein 823) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF799.

UniProtKB/Swiss-Prot for ZNF823 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF823 Gene

Genomics for ZNF823 Gene

Regulatory Elements for ZNF823 Gene

Enhancers for ZNF823 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F011693 1 FANTOM5 Ensembl ENCODE 13.4 +44.5 44501 2.2 ATF1 PKNOX1 ARID4B SIN3A FEZF1 GLI4 ZNF48 ZNF2 SLC30A9 GLIS2 ZNF44 ZNF700 ZNF878 WDR83OS ZNF136 ZNF823 ZNF799 ZNF563 SWSAP1 YIPF2
GH19F011691 0.6 ENCODE 12.1 +46.9 46872 0.4 SOX13 GATAD2A HNF1A SAP130 TEAD1 HLF ZBTB33 TEAD3 ZNF823 ZNF441 ACP5 GC19M011701 GC19P011691
GH19F011633 0.6 ENCODE 11.7 +104.6 104646 1.5 SOX13 GATAD2A SOX5 TEAD1 CEBPG CEBPA HNF4G NR2F6 SETDB1 ZNF823 VN2R12P ZNF887P
GH19F011623 0.9 Ensembl ENCODE 11.2 +114.5 114459 1.8 GATAD2A KLF1 PKNOX1 NFIA L3MBTL2 NRF1 ZNF48 YY1 ATF3 WT1 ZNF823 ACP5 VN2R12P ZNF887P
GH19F011639 1 ENCODE 11 +99.0 98969 1.8 PKNOX1 ARID4B SIN3A ZNF48 ZNF2 GLIS2 ZNF416 KLF7 FOS SP3 ZNF700 ZNF627 ZNF44 PRKCSH ZNF564 ZNF763 ZNF136 ZNF799 ZNF878 TIMM29
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ZNF823 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF823 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000343574 409 2400 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZNF2 YY1 FOS ZNF263 SP3

Genomic Location for ZNF823 Gene

Chromosome:
19
Start:
11,721,265 bp from pter
End:
11,739,009 bp from pter
Size:
17,745 bases
Orientation:
Minus strand

Genomic View for ZNF823 Gene

Genes around ZNF823 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF823 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF823 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF823 Gene

Proteins for ZNF823 Gene

  • Protein details for ZNF823 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P16415-ZN823_HUMAN
    Recommended name:
    Zinc finger protein 823
    Protein Accession:
    P16415
    Secondary Accessions:
    • A0PJL4
    • B7Z8D4
    • Q6P4A9

    Protein attributes for ZNF823 Gene

    Size:
    610 amino acids
    Molecular mass:
    70270 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAA36064.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF823 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF823 Gene

Post-translational modifications for ZNF823 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF823 Gene

No data available for DME Specific Peptides for ZNF823 Gene

Domains & Families for ZNF823 Gene

Gene Families for ZNF823 Gene

Protein Domains for ZNF823 Gene

Suggested Antigen Peptide Sequences for ZNF823 Gene

Graphical View of Domain Structure for InterPro Entry

P16415

UniProtKB/Swiss-Prot:

ZN823_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 16 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 16 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF823: view

Function for ZNF823 Gene

Molecular function for ZNF823 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF823 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF823: view
genes like me logo Genes that share phenotypes with ZNF823: view

Animal Model Products

miRNA for ZNF823 Gene

miRTarBase miRNAs that target ZNF823

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF823 Gene

Localization for ZNF823 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF823 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF823 Gene COMPARTMENTS Subcellular localization image for ZNF823 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF823 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF823: view

Pathways & Interactions for ZNF823 Gene

SuperPathways for ZNF823 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF823 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF823: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF823 Gene

Transcripts for ZNF823 Gene

Unigene Clusters for ZNF823 Gene

Zinc finger protein 823:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF823 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d
SP1:
SP2: -
SP3: -
SP4: - -

Relevant External Links for ZNF823 Gene

GeneLoc Exon Structure for
ZNF823
ECgene alternative splicing isoforms for
ZNF823

Expression for ZNF823 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF823 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF823 Gene



NURSA nuclear receptor signaling pathways regulating expression of ZNF823 Gene:

ZNF823

SOURCE GeneReport for Unigene cluster for ZNF823 Gene:

Hs.142167
genes like me logo Genes that share expression patterns with ZNF823: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZNF823 Gene

Orthologs for ZNF823 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF823 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF823 34
  • 99.56 (n)
cow
(Bos Taurus)
Mammalia -- 35
  • 50 (a)
ManyToMany
Species where no ortholog for ZNF823 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF823 Gene

ENSEMBL:
Gene Tree for ZNF823 (if available)
TreeFam:
Gene Tree for ZNF823 (if available)

Paralogs for ZNF823 Gene

(521) SIMAP similar genes for ZNF823 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF823: view

Variants for ZNF823 Gene

Sequence variations from dbSNP and Humsavar for ZNF823 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10404024 -- 11,738,426(+) gaggc(A/G)gatct intron-variant
rs10405666 -- 11,725,962(+) gtggc(C/T)catgc intron-variant
rs10410639 -- 11,734,316(+) AACAA(A/G)CAGCT intron-variant
rs10412024 -- 11,738,429(+) gcgga(G/T)ctggg intron-variant
rs10413313 -- 11,740,267(+) TGGTA(C/G)CCATG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF823 Gene

Variant ID Type Subtype PubMed ID
nsv1072325 CNV deletion 25765185
nsv518441 CNV loss 19592680
nsv522659 CNV loss 19592680
nsv525966 CNV gain 19592680
nsv960789 CNV duplication 23825009

Variation tolerance for ZNF823 Gene

Residual Variation Intolerance Score: 34.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.23; 24.57% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF823 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF823

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF823 Gene

Disorders for ZNF823 Gene

Relevant External Links for ZNF823

Genetic Association Database (GAD)
ZNF823
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF823

No disorders were found for ZNF823 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF823 Gene

Publications for ZNF823 Gene

  1. A human MAP kinase interactome. (PMID: 20936779) Bandyopadhyay S. … Ideker T. (Nat. Methods 2010) 3 64
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for ZNF823 Gene

Sources for ZNF823 Gene

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