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Aliases for ZNF814 Gene

Aliases for ZNF814 Gene

  • Zinc Finger Protein 814 2 3 5
  • Putative Zinc Finger Protein LOC730051 4

External Ids for ZNF814 Gene

Previous GeneCards Identifiers for ZNF814 Gene

  • GC19U900727
  • GC19M063072
  • GC19M058380
  • GC19M054692
  • GC19M058361

Summaries for ZNF814 Gene

GeneCards Summary for ZNF814 Gene

ZNF814 (Zinc Finger Protein 814) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF208.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF814 Gene

Genomics for ZNF814 Gene

Regulatory Elements for ZNF814 Gene

Enhancers for ZNF814 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G057801 1.7 FANTOM5 Ensembl ENCODE dbSUPER 18.9 +85.1 85141 5.3 HDAC1 SIN3A ZSCAN9 ZBTB40 ZNF766 ZNF143 IKZF2 U2AF2 ZNF202 MIER1 ENSG00000269867 ZNF814 ZNF587 ZNF586 LOC100128398 ZNF154 ZNF418 ZNF552 ZNF549 ZNF135
GH19G057798 1.1 Ensembl ENCODE dbSUPER 18.8 +89.7 89695 2.4 ZNF202 CTCF JUND POLR2A SCRT2 SMC3 ZBTB33 PRDM1 RAD21 CHAMP1 ENSG00000269867 ZNF814 ZNF587 PIR55332 ZNF552
GH19G057769 1 ENCODE 19.1 +118.9 118851 2.4 PKNOX1 ATF1 CREB3L1 WRNIP1 SIN3A YY1 ETS1 ZNF766 CBX5 ELK1 ZNF814 ZNF776 ZNF586 ZNF671 ZNF417 ZNF154 ZNF256 RPL19P19 ZSCAN4 ZNF419
GH19G057746 1 ENCODE 15.1 +142.1 142070 1.7 PKNOX1 ATF1 CREB3L1 WRNIP1 ZNF133 SIN3A GLI4 ZNF2 YY1 ETS1 ZNF814 ZNF264 ZNF805 TRIM28 ZSCAN1 ZNF548 ZNF543 ZNF134 ZNF586 ZNF776
GH19G057738 0.6 Ensembl 14.9 +150.4 150374 0.2 CTCF REST RAD21 IKZF1 SMC3 ZNF143 ZBTB33 IKZF2 THAP11 ZNF814 ZNF256 RPL19P19 ZNF586 ZNF776 ZNF671
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF814 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF814 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000111835 574 1801 TBP PKNOX1 TBL1XR1 WRNIP1 SIN3A RAD21 ZBTB40 YY1 ETS1 EGR1

Genomic Location for ZNF814 Gene

Chromosome:
19
Start:
57,848,731 bp from pter
End:
57,889,074 bp from pter
Size:
40,344 bases
Orientation:
Minus strand

Genomic View for ZNF814 Gene

Genes around ZNF814 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF814 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF814 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF814 Gene

Proteins for ZNF814 Gene

  • Protein details for ZNF814 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B7Z6K7-ZN814_HUMAN
    Recommended name:
    Putative uncharacterized zinc finger protein 814
    Protein Accession:
    B7Z6K7
    Secondary Accessions:
    • A6NF35

    Protein attributes for ZNF814 Gene

    Size:
    855 amino acids
    Molecular mass:
    97337 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF814 Gene

Post-translational modifications for ZNF814 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF814 Gene

Domains & Families for ZNF814 Gene

Gene Families for ZNF814 Gene

Protein Domains for ZNF814 Gene

Suggested Antigen Peptide Sequences for ZNF814 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZNF814: view

No data available for UniProtKB/Swiss-Prot for ZNF814 Gene

Function for ZNF814 Gene

Gene Ontology (GO) - Molecular Function for ZNF814 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF814: view

Animal Model Products

CRISPR Products

miRNA for ZNF814 Gene

miRTarBase miRNAs that target ZNF814

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF814 Gene

Localization for ZNF814 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF814 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF814 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with ZNF814: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ZNF814 Gene

Pathways & Interactions for ZNF814 Gene

SuperPathways for ZNF814 Gene

No Data Available

Interacting Proteins for ZNF814 Gene

Gene Ontology (GO) - Biological Process for ZNF814 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0045892 negative regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF814: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF814 Gene

Drugs & Compounds for ZNF814 Gene

No Compound Related Data Available

Transcripts for ZNF814 Gene

mRNA/cDNA for ZNF814 Gene

(2) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(15) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF814 Gene

Zinc finger protein 814:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF814 Gene

No ASD Table

Relevant External Links for ZNF814 Gene

GeneLoc Exon Structure for
ZNF814
ECgene alternative splicing isoforms for
ZNF814

Expression for ZNF814 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF814 Gene

Protein differential expression in normal tissues from HIPED for ZNF814 Gene

This gene is overexpressed in Lung (57.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF814 Gene



Protein tissue co-expression partners for ZNF814 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF814 Gene:

ZNF814

SOURCE GeneReport for Unigene cluster for ZNF814 Gene:

Hs.634143
genes like me logo Genes that share expression patterns with ZNF814: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF814 Gene

Orthologs for ZNF814 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF814 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF814 34
  • 96.45 (n)
dog
(Canis familiaris)
Mammalia LOC102152013 34
  • 67.42 (n)
-- 35
  • 45 (a)
OneToMany
-- 35
  • 40 (a)
OneToMany
cow
(Bos Taurus)
Mammalia ZNF154 34
  • 67.3 (n)
-- 35
  • 50 (a)
OneToMany
-- 35
  • 50 (a)
OneToMany
-- 35
  • 41 (a)
OneToMany
-- 35
  • 39 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 38 (a)
ManyToMany
chicken
(Gallus gallus)
Aves ZNF814 35
  • 41 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF814 35
  • 39 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii CU672268.1 35
  • 43 (a)
ManyToMany
si:zfos-44a5.2 35
  • 43 (a)
ManyToMany
AL954741.1 35
  • 42 (a)
ManyToMany
BX640537.2 35
  • 41 (a)
ManyToMany
CABZ01006831.1 35
  • 41 (a)
ManyToMany
CABZ01075191.1 35
  • 41 (a)
ManyToMany
si:ch211-235i11.2 35
  • 40 (a)
ManyToMany
zgc:174712 35
  • 40 (a)
ManyToMany
CABZ01006835.1 35
  • 38 (a)
ManyToMany
CABZ01048402.1 35
  • 37 (a)
ManyToMany
BX000701.1 35
  • 36 (a)
ManyToMany
si:dkey-20i20.5 35
  • 36 (a)
ManyToMany
zgc:113389 35
  • 36 (a)
ManyToMany
FP326649.1 35
  • 35 (a)
ManyToMany
Species where no ortholog for ZNF814 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF814 Gene

ENSEMBL:
Gene Tree for ZNF814 (if available)
TreeFam:
Gene Tree for ZNF814 (if available)

Paralogs for ZNF814 Gene

(532) SIMAP similar genes for ZNF814 Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with ZNF814: view

Variants for ZNF814 Gene

Sequence variations from dbSNP and Humsavar for ZNF814 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000045484 -- 57,869,547(+) GACTA(C/T)GTTAA utr-variant-3-prime
rs1000131707 -- 57,881,215(+) GGACG(C/T)CTACC intron-variant
rs1000411453 -- 57,870,567(+) TTTAG(A/G)TTATT utr-variant-3-prime
rs1000481179 -- 57,881,684(+) CTGCT(G/T)CCTTG intron-variant
rs1000675664 -- 57,871,589(+) TTCTT(A/G)GGATC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF814 Gene

Variant ID Type Subtype PubMed ID
dgv3686n100 CNV gain 25217958
esv1001775 CNV deletion 20482838
esv2302097 CNV deletion 18987734
esv2719092 CNV deletion 23290073
esv2719093 CNV deletion 23290073
esv2763213 CNV gain 21179565
esv3644913 CNV gain 21293372
esv3644914 CNV loss 21293372
esv3893258 CNV gain 25118596
nsv1066059 CNV gain 25217958
nsv1071953 CNV deletion 25765185
nsv1135860 CNV deletion 24896259
nsv1152353 CNV deletion 26484159
nsv7311 OTHER inversion 18451855
nsv961253 CNV duplication 23825009

Variation tolerance for ZNF814 Gene

Residual Variation Intolerance Score: 65.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.16; 39.22% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF814 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF814

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF814 Gene

Disorders for ZNF814 Gene

Relevant External Links for ZNF814

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF814

No disorders were found for ZNF814 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF814 Gene

Publications for ZNF814 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4 64
  3. Uncovering global SUMOylation signaling networks in a site-specific manner. (PMID: 25218447) Hendriks I.A. … Vertegaal A.C. (Nat. Struct. Mol. Biol. 2014) 4 64
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ZNF814 Gene

Sources for ZNF814 Gene

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