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Aliases for ZNF814 Gene

Aliases for ZNF814 Gene

  • Zinc Finger Protein 814 2 3 5
  • Putative Zinc Finger Protein LOC730051 4

External Ids for ZNF814 Gene

Previous GeneCards Identifiers for ZNF814 Gene

  • GC19U900727
  • GC19M063072
  • GC19M058380
  • GC19M054692
  • GC19M058361

Summaries for ZNF814 Gene

GeneCards Summary for ZNF814 Gene

ZNF814 (Zinc Finger Protein 814) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF418.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF814 Gene

Genomics for ZNF814 Gene

Regulatory Elements for ZNF814 Gene

Enhancers for ZNF814 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F057801 1.5 FANTOM5 Ensembl ENCODE 18.9 +85.1 85141 5.3 HDAC1 CTCF KLF1 SAP130 SIN3A ZNF644 ZBTB40 ZSCAN9 ZNF766 POLR2A ENSG00000269867 ZNF587 TRIM28 ZNF324B ZNF814 ZNF264 ZNF417 ZNF550 ZNF543 ZNF548
GH19F057769 1 ENCODE 19.1 +118.9 118851 2.4 ATF1 PKNOX1 CREB3L1 WRNIP1 SIN3A ETS1 YY1 ELK1 ZNF143 FOS ZNF814 ZNF776 ZNF586 ZNF805 ZNF671 ZNF417 ZNF154 ZNF256 RPL19P19 ZSCAN4
GH19F057798 0.9 Ensembl ENCODE 18.8 +89.7 89674 2.4 CTCF ZNF202 JUND POLR2A SCRT2 ZBTB33 PRDM1 RAD21 CHAMP1 ZNF587 TRIM28 ENSG00000269867 ZNF324B ZNF814 ZNF264 ZNF417 ZNF550 ZNF543 ZNF548
GH19F057746 1 ENCODE 15.1 +142.1 142070 1.7 PKNOX1 ATF1 CREB3L1 WRNIP1 ZNF133 SIN3A GLI4 ZNF2 ETS1 YY1 ZNF805 ZNF814 ZNF264 TRIM28 ZNF548 ZNF543 ZNF134 RPS5 ZNF586 ZNF776
GH19F057738 0.6 Ensembl 14.9 +150.5 150480 0.4 CTCF IKZF1 SMC3 ZBTB33 REST RAD21 THAP11 ZNF814 RPL19P19 ZNF256 ZNF586 ZNF776 ZNF671
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF814 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF814 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for ZNF814 Gene

57,848,731 bp from pter
57,889,074 bp from pter
40,344 bases
Minus strand

Genomic View for ZNF814 Gene

Genes around ZNF814 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF814 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF814 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF814 Gene

Proteins for ZNF814 Gene

  • Protein details for ZNF814 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative uncharacterized zinc finger protein 814
    Protein Accession:
    Secondary Accessions:
    • A6NF35

    Protein attributes for ZNF814 Gene

    855 amino acids
    Molecular mass:
    97337 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF814 Gene

Post-translational modifications for ZNF814 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF814 Gene

Domains & Families for ZNF814 Gene

Gene Families for ZNF814 Gene

Protein Domains for ZNF814 Gene

Suggested Antigen Peptide Sequences for ZNF814 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Contains 23 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Contains 23 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF814: view

Function for ZNF814 Gene

Gene Ontology (GO) - Molecular Function for ZNF814 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF814: view

Animal Model Products

miRNA for ZNF814 Gene

miRTarBase miRNAs that target ZNF814

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF814 Gene

Localization for ZNF814 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF814 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF814 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with ZNF814: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ZNF814 Gene

Pathways & Interactions for ZNF814 Gene

SuperPathways for ZNF814 Gene

No Data Available

Interacting Proteins for ZNF814 Gene

Gene Ontology (GO) - Biological Process for ZNF814 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
genes like me logo Genes that share ontologies with ZNF814: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF814 Gene

Transcripts for ZNF814 Gene

mRNA/cDNA for ZNF814 Gene

(2) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(15) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF814 Gene

Zinc finger protein 814:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF814 Gene

No ASD Table

Relevant External Links for ZNF814 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF814 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF814 Gene

Protein differential expression in normal tissues from HIPED for ZNF814 Gene

This gene is overexpressed in Lung (57.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF814 Gene

Protein tissue co-expression partners for ZNF814 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF814 Gene:


SOURCE GeneReport for Unigene cluster for ZNF814 Gene:

genes like me logo Genes that share expression patterns with ZNF814: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF814 Gene

Orthologs for ZNF814 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF814 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF814 34
  • 96.45 (n)
(Canis familiaris)
Mammalia LOC102152013 34
  • 67.42 (n)
-- 35
  • 45 (a)
-- 35
  • 40 (a)
(Bos Taurus)
Mammalia ZNF154 34
  • 67.3 (n)
-- 35
  • 50 (a)
-- 35
  • 50 (a)
-- 35
  • 41 (a)
-- 35
  • 39 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 38 (a)
(Gallus gallus)
Aves ZNF814 35
  • 41 (a)
(Anolis carolinensis)
Reptilia ZNF814 35
  • 39 (a)
(Danio rerio)
Actinopterygii CU672268.1 35
  • 43 (a)
si:zfos-44a5.2 35
  • 43 (a)
AL954741.1 35
  • 42 (a)
BX640537.2 35
  • 41 (a)
CABZ01006831.1 35
  • 41 (a)
CABZ01075191.1 35
  • 41 (a)
si:ch211-235i11.2 35
  • 40 (a)
zgc:174712 35
  • 40 (a)
CABZ01006835.1 35
  • 38 (a)
CABZ01048402.1 35
  • 37 (a)
BX000701.1 35
  • 36 (a)
si:dkey-20i20.5 35
  • 36 (a)
zgc:113389 35
  • 36 (a)
FP326649.1 35
  • 35 (a)
Species where no ortholog for ZNF814 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF814 Gene

Gene Tree for ZNF814 (if available)
Gene Tree for ZNF814 (if available)

Paralogs for ZNF814 Gene

(532) SIMAP similar genes for ZNF814 Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with ZNF814: view

Variants for ZNF814 Gene

Sequence variations from dbSNP and Humsavar for ZNF814 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10402091 -- 57,886,107(+) ACAAC(A/G)CCACA intron-variant
rs10409034 -- 57,878,435(+) tcgaa(A/C)ggctt intron-variant
rs10410028 -- 57,887,196(+) gaaaa(C/T)aaaac intron-variant
rs10411513 -- 57,887,152(+) cattg(C/T)actcc intron-variant
rs10412589 -- 57,874,946(+) CCTCT(A/G)TAGGG reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for ZNF814 Gene

Variant ID Type Subtype PubMed ID
nsv961253 CNV duplication 23825009
nsv7311 OTHER inversion 18451855
nsv1152353 CNV deletion 26484159
nsv1135860 CNV deletion 24896259
nsv1071953 CNV deletion 25765185
nsv1066059 CNV gain 25217958
esv3893258 CNV gain 25118596
esv3644914 CNV loss 21293372
esv3644913 CNV gain 21293372
esv2763213 CNV gain 21179565
esv2719093 CNV deletion 23290073
esv2719092 CNV deletion 23290073
esv2302097 CNV deletion 18987734
esv1001775 CNV deletion 20482838
dgv3686n100 CNV gain 25217958

Variation tolerance for ZNF814 Gene

Residual Variation Intolerance Score: 65.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.16; 39.22% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF814 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF814 Gene

Disorders for ZNF814 Gene

Relevant External Links for ZNF814

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF814 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF814 Gene

Publications for ZNF814 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4 64
  3. Uncovering global SUMOylation signaling networks in a site-specific manner. (PMID: 25218447) Hendriks I.A. … Vertegaal A.C. (Nat. Struct. Mol. Biol. 2014) 4 64
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ZNF814 Gene

Sources for ZNF814 Gene

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