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Aliases for ZNF812 Gene

Aliases for ZNF812 Gene

  • Zinc Finger Protein 812 2 3

External Ids for ZNF812 Gene

Previous GeneCards Identifiers for ZNF812 Gene

  • GC00U922274
  • GC19M009663
  • GC19M009800
  • GC19M009381

Summaries for ZNF812 Gene

GeneCards Summary for ZNF812 Gene

ZNF812 (Zinc Finger Protein 812) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF426.

UniProtKB/Swiss-Prot for ZNF812 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF812 Gene

Genomics for ZNF812 Gene

Regulatory Elements for ZNF812 Gene

Genomic Location for ZNF812 Gene

Chromosome:
19
Start:
9,688,855 bp from pter
End:
9,700,817 bp from pter
Size:
11,963 bases
Orientation:
Minus strand

Genomic View for ZNF812 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF812 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF812 Gene

Proteins for ZNF812 Gene

  • Protein details for ZNF812 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C7V5-ZN812_HUMAN
    Recommended name:
    Putative zinc finger protein 812
    Protein Accession:
    P0C7V5

    Protein attributes for ZNF812 Gene

    Size:
    454 amino acids
    Molecular mass:
    51518 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF812 Gene

Proteomics data for ZNF812 Gene at MOPED

Post-translational modifications for ZNF812 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF812 Gene

No data available for DME Specific Peptides for ZNF812 Gene

Domains & Families for ZNF812 Gene

Protein Domains for ZNF812 Gene

Suggested Antigen Peptide Sequences for ZNF812 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0C7V5

UniProtKB/Swiss-Prot:

ZN812_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 10 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 10 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF812: view

No data available for Gene Families for ZNF812 Gene

Function for ZNF812 Gene

Molecular function for ZNF812 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF812 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA --
GO:0003676 nucleic acid binding --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF812: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF812 Gene

Localization for ZNF812 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF812 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF812 Gene COMPARTMENTS Subcellular localization image for ZNF812 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF812 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005654 nucleoplasm IBA --
genes like me logo Genes that share ontologies with ZNF812: view

Pathways & Interactions for ZNF812 Gene

SuperPathways for ZNF812 Gene

No Data Available

Interacting Proteins for ZNF812 Gene

Gene Ontology (GO) - Biological Process for ZNF812 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF812: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF812 Gene

Drugs & Compounds for ZNF812 Gene

No Compound Related Data Available

Transcripts for ZNF812 Gene

mRNA/cDNA for ZNF812 Gene

(12) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF812 Gene

Zinc finger protein 812:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF812 Gene

No ASD Table

Relevant External Links for ZNF812 Gene

GeneLoc Exon Structure for
ZNF812
ECgene alternative splicing isoforms for
ZNF812

Expression for ZNF812 Gene

mRNA expression in normal human tissues for ZNF812 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF812 Gene

This gene is overexpressed in Esophagus - Mucosa (x24.3), Vagina (x5.9), and Cervix - Ectocervix (x4.9).

Protein differential expression in normal tissues from HIPED for ZNF812 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF812 Gene



SOURCE GeneReport for Unigene cluster for ZNF812 Gene Hs.626848

genes like me logo Genes that share expression patterns with ZNF812: view

Protein tissue co-expression partners for ZNF812 Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF812 Gene

Orthologs for ZNF812 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF812 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF562 35
  • 97.65 (n)
  • 95.81 (a)
ZNF812 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 26 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 35 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp266 36
  • 45 (a)
OneToMany
Species with no ortholog for ZNF812:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF812 Gene

ENSEMBL:
Gene Tree for ZNF812 (if available)
TreeFam:
Gene Tree for ZNF812 (if available)

Paralogs for ZNF812 Gene

Paralogs for ZNF812 Gene

(411) SIMAP similar genes for ZNF812 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF812: view

Variants for ZNF812 Gene

Sequence variations from dbSNP and Humsavar for ZNF812 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs527489138 -- 9,693,104(+) TTAAC(-/A)AAAAA intron-variant
rs527369432 -- 9,700,447(+) AGCCA(A/G)CGCGG utr-variant-5-prime
rs527295931 -- 9,696,651(+) CTCAA(A/G)TGATC intron-variant
rs527288395 -- 9,691,277(+) GATGA(A/G)GGGAT intron-variant
rs527250773 -- 9,701,724(+) TATAT(-/ATAC)ACGTA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF812 Gene

Variant ID Type Subtype PubMed ID
esv2718158 CNV Deletion 23290073
nsv518826 CNV Loss 19592680

Variation tolerance for ZNF812 Gene

Residual Variation Intolerance Score: 92.58% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.79; 89.51% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF812 Gene

HapMap Linkage Disequilibrium report
ZNF812

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF812 Gene

Disorders for ZNF812 Gene

Relevant External Links for ZNF812

Genetic Association Database (GAD)
ZNF812
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF812
genes like me logo Genes that share disorders with ZNF812: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF812 Gene

Publications for ZNF812 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 67

Products for ZNF812 Gene

Sources for ZNF812 Gene

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