Aliases for ZNF81 Gene
External Ids for ZNF81 Gene
Previous HGNC Symbols for ZNF81 Gene
Previous GeneCards Identifiers for ZNF81 Gene
This gene encodes a protein that likely functions as a transcription factor. The protein contains an N-terminal KRAB domain and several C2H2-type zinc finger motifs. Mutations in this gene cause an X-linked form of intellectual disability (MRX45). Microduplication of a region of chromosome X including this gene has also been associated with other forms of intellectual disability. [provided by RefSeq, Jul 2017]
GeneCards Summary for ZNF81 Gene
ZNF81 (Zinc Finger Protein 81) is a Protein Coding gene. Diseases associated with ZNF81 include X-Linked Non-Specific Intellectual Disability and Aland Island Eye Disease. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF41.
UniProtKB/Swiss-Prot for ZNF81 Gene
May be involved in transcriptional regulation.