Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF808 Gene

Aliases for ZNF808 Gene

  • Zinc Finger Protein 808 2 3 5

External Ids for ZNF808 Gene

Previous GeneCards Identifiers for ZNF808 Gene

  • GC19P057722
  • GC19P057751
  • GC19P053030
  • GC19P049362

Summaries for ZNF808 Gene

GeneCards Summary for ZNF808 Gene

ZNF808 (Zinc Finger Protein 808) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF845.

UniProtKB/Swiss-Prot for ZNF808 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF808 Gene

Genomics for ZNF808 Gene

Regulatory Elements for ZNF808 Gene

Enhancers for ZNF808 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G051687 1.8 FANTOM5 ENCODE dbSUPER 46.2 -837.2 -837162 6.9 CREB3L1 DMAP1 FEZF1 YY1 ZNF143 ZNF263 SP3 NFYC MEF2D ZNF610 ZNF808 ZNF836 ZNF616 ZNF841 ZNF137P ENSG00000268970 ZNF766 ENSG00000269825 ZNF528 ZNF175
GH19G052137 1.4 FANTOM5 ENCODE 33.7 -388.0 -388021 3.3 PKNOX1 FOXA2 CREB3L1 ARNT WRNIP1 ARID4B SIN3A DMAP1 YY1 ZNF143 ZNF808 ZNF137P ENSG00000268970 ZNF816 ZNF350 ZNF836 ZNF600 ZNF468 ZNF616 ZNF841
GH19G053364 1.1 ENCODE 24 +838.0 838039 1.6 HDGF HNRNPUL1 CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZBTB7B ZNF207 KLF13 ZNF525 ZNF808 ZNF845 ENSG00000268970 ZNF137P ZNF765 ZNF816 ENSG00000269825 ENSG00000269001 ZNF813
GH19G053389 1 Ensembl ENCODE 24 +862.3 862277 1.8 KLF1 CREB3L1 SUZ12 ZSCAN4 ZNF76 DEAF1 FOSL1 ZNF766 DIDO1 ZNF366 ZNF525 ZNF808 ENSG00000268970 ZNF845 ZNF137P ZNF765 ZNF816 ENSG00000269825 ENSG00000269001 ZNF813
GH19G052733 1.4 FANTOM5 ENCODE 10.9 +207.6 207618 2.8 HDGF ARID4B SIN3A ZNF48 ELK1 SP3 SP5 REST ZNF518A ZNF592 ZNF611 ZNF137P ENSG00000268970 ZNF701 TPM3P9 ZNF525 ZNF665 TPM3P6 ZNF28 ZNF845
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF808 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF808 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000111298 48 1801 ATF1 ARID4B SIN3A GLI4 ZNF48 CBX5 ELK1 ZNF143 SP3 SP5

Genomic Location for ZNF808 Gene

Chromosome:
19
Start:
52,527,652 bp from pter
End:
52,570,178 bp from pter
Size:
42,527 bases
Orientation:
Plus strand

Genomic View for ZNF808 Gene

Genes around ZNF808 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF808 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF808 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF808 Gene

Proteins for ZNF808 Gene

  • Protein details for ZNF808 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N4W9-ZN808_HUMAN
    Recommended name:
    Zinc finger protein 808
    Protein Accession:
    Q8N4W9
    Secondary Accessions:
    • Q68CN7

    Protein attributes for ZNF808 Gene

    Size:
    903 amino acids
    Molecular mass:
    104825 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH33230.1; Type=Miscellaneous discrepancy; Note=In 3-UTR.; Evidence={ECO:0000305}; Sequence=AAI30352.1; Type=Miscellaneous discrepancy; Note=In 3-UTR.; Evidence={ECO:0000305}; Sequence=AAI30354.1; Type=Miscellaneous discrepancy; Note=In 3-UTR.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF808 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF808 Gene

Post-translational modifications for ZNF808 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF808 Gene

Domains & Families for ZNF808 Gene

Gene Families for ZNF808 Gene

Protein Domains for ZNF808 Gene

Suggested Antigen Peptide Sequences for ZNF808 Gene

Graphical View of Domain Structure for InterPro Entry

Q8N4W9

UniProtKB/Swiss-Prot:

ZN808_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF808: view

Function for ZNF808 Gene

Molecular function for ZNF808 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF808 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF808: view

Phenotypes for ZNF808 Gene

GenomeRNAi human phenotypes for ZNF808:
genes like me logo Genes that share phenotypes with ZNF808: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF808 Gene

Localization for ZNF808 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF808 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF808 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF808 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF808: view

Pathways & Interactions for ZNF808 Gene

SuperPathways for ZNF808 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF808 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA,IEA --
genes like me logo Genes that share ontologies with ZNF808: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF808 Gene

Drugs & Compounds for ZNF808 Gene

No Compound Related Data Available

Transcripts for ZNF808 Gene

Unigene Clusters for ZNF808 Gene

Zinc finger protein 808:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF808 Gene

No ASD Table

Relevant External Links for ZNF808 Gene

GeneLoc Exon Structure for
ZNF808
ECgene alternative splicing isoforms for
ZNF808

Expression for ZNF808 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF808 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF808 Gene



Protein tissue co-expression partners for ZNF808 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF808 Gene:

ZNF808

SOURCE GeneReport for Unigene cluster for ZNF808 Gene:

Hs.729294

Evidence on tissue expression from TISSUES for ZNF808 Gene

  • Eye(4.1)
genes like me logo Genes that share expression patterns with ZNF808: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF808 Gene

Orthologs for ZNF808 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF808 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF808 34
  • 98.53 (n)
mouse
(Mus musculus)
Mammalia Zfp51 35
  • 43 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 40 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 48 (a)
ManyToMany
-- 35
  • 44 (a)
ManyToMany
-- 35
  • 42 (a)
ManyToMany
-- 35
  • 39 (a)
ManyToMany
CSA.1668 35
  • 36 (a)
ManyToMany
-- 35
  • 35 (a)
ManyToMany
Species where no ortholog for ZNF808 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF808 Gene

ENSEMBL:
Gene Tree for ZNF808 (if available)
TreeFam:
Gene Tree for ZNF808 (if available)

Paralogs for ZNF808 Gene

(665) SIMAP similar genes for ZNF808 Gene using alignment to 7 proteins:

Pseudogenes.org Pseudogenes for ZNF808 Gene

genes like me logo Genes that share paralogs with ZNF808: view

Variants for ZNF808 Gene

Sequence variations from dbSNP and Humsavar for ZNF808 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000141530 -- 52,565,652(+) TGAGC(C/T)AGCCT nc-transcript-variant
rs1000220837 -- 52,558,229(+) TACAG(C/G)CGCCC intron-variant
rs1000244577 -- 52,552,967(+) TCTCA(A/C)TCTTT intron-variant
rs1000334833 -- 52,563,487(+) GTAAT(C/G)ATGCT nc-transcript-variant
rs1000342035 -- 52,531,272(+) GGTTC(A/G)AGACC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF808 Gene

Variant ID Type Subtype PubMed ID
dgv3627n100 CNV gain 25217958
esv2718785 CNV deletion 23290073
esv2718786 CNV deletion 23290073
esv3893233 CNV loss 25118596
nsv1063648 CNV gain 25217958
nsv1065584 CNV loss 25217958
nsv1146332 OTHER inversion 26484159
nsv436854 CNV insertion 17901297
nsv510772 CNV deletion 20534489
nsv580026 CNV loss 21841781
nsv833874 CNV loss 17160897
nsv978841 CNV duplication 23825009

Variation tolerance for ZNF808 Gene

Residual Variation Intolerance Score: 71.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.84; 73.96% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF808 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF808

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF808 Gene

Disorders for ZNF808 Gene

Relevant External Links for ZNF808

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF808

No disorders were found for ZNF808 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF808 Gene

Publications for ZNF808 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  2. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3 64
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64

Products for ZNF808 Gene

Sources for ZNF808 Gene

Content
Loading form....