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Aliases for ZNF804B Gene

Aliases for ZNF804B Gene

  • Zinc Finger Protein 804B 2 3 5
  • Zinc Finger 804B 2

External Ids for ZNF804B Gene

Previous GeneCards Identifiers for ZNF804B Gene

  • GC07P088227
  • GC07P088388
  • GC07P082997

Summaries for ZNF804B Gene

GeneCards Summary for ZNF804B Gene

ZNF804B (Zinc Finger Protein 804B) is a Protein Coding gene. Among its related pathways are Gene Expression. An important paralog of this gene is ZNF804A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF804B Gene

Genomics for ZNF804B Gene

Regulatory Elements for ZNF804B Gene

Genomic Location for ZNF804B Gene

Chromosome:
7
Start:
88,759,368 bp from pter
End:
89,337,057 bp from pter
Size:
577,690 bases
Orientation:
Plus strand

Genomic View for ZNF804B Gene

Genes around ZNF804B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF804B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF804B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF804B Gene

Proteins for ZNF804B Gene

  • Protein details for ZNF804B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A4D1E1-Z804B_HUMAN
    Recommended name:
    Zinc finger protein 804B
    Protein Accession:
    A4D1E1
    Secondary Accessions:
    • B2RTV2
    • Q7Z714
    • Q96MN7

    Protein attributes for ZNF804B Gene

    Size:
    1349 amino acids
    Molecular mass:
    152573 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF804B Gene

Proteomics data for ZNF804B Gene at MOPED

Post-translational modifications for ZNF804B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF804B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF804B Gene

Domains & Families for ZNF804B Gene

Protein Domains for ZNF804B Gene

Suggested Antigen Peptide Sequences for ZNF804B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A4D1E1

UniProtKB/Swiss-Prot:

Z804B_HUMAN :
  • Contains 1 C2H2-type zinc finger.
Similarity:
  • Contains 1 C2H2-type zinc finger.
genes like me logo Genes that share domains with ZNF804B: view

No data available for Gene Families for ZNF804B Gene

Function for ZNF804B Gene

Phenotypes for ZNF804B Gene

GenomeRNAi human phenotypes for ZNF804B:
genes like me logo Genes that share phenotypes with ZNF804B: view

Animal Model Products

CRISPR Products

miRNA for ZNF804B Gene

miRTarBase miRNAs that target ZNF804B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF804B Gene

Localization for ZNF804B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF804B Gene COMPARTMENTS Subcellular localization image for ZNF804B gene
Compartment Confidence
nucleus 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZNF804B Gene

Pathways & Interactions for ZNF804B Gene

SuperPathways for ZNF804B Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF804B: view

Pathways by source for ZNF804B Gene

2 Reactome pathways for ZNF804B Gene

Interacting Proteins for ZNF804B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000329638%0d%0a9606.ENSP00000262127%0d%0a
Selected Interacting proteins: ENSP00000329638 for ZNF804B Gene via STRING

Symbol External ID(s) Details
CEP76

Gene Ontology (GO) - Biological Process for ZNF804B Gene

None

No data available for SIGNOR curated interactions for ZNF804B Gene

Drugs & Compounds for ZNF804B Gene

No Compound Related Data Available

Transcripts for ZNF804B Gene

mRNA/cDNA for ZNF804B Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF804B Gene

Zinc finger protein 804B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF804B Gene

No ASD Table

Relevant External Links for ZNF804B Gene

GeneLoc Exon Structure for
ZNF804B
ECgene alternative splicing isoforms for
ZNF804B

Expression for ZNF804B Gene

mRNA expression in normal human tissues for ZNF804B Gene

mRNA differential expression in normal tissues according to GTEx for ZNF804B Gene

This gene is overexpressed in Thyroid (x33.1) and Pancreas (x4.6).

Protein differential expression in normal tissues from HIPED for ZNF804B Gene

This gene is overexpressed in Adipocyte (66.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF804B Gene



SOURCE GeneReport for Unigene cluster for ZNF804B Gene Hs.684410

genes like me logo Genes that share expression patterns with ZNF804B: view

Protein tissue co-expression partners for ZNF804B Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF804B Gene

Orthologs for ZNF804B Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF804B Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF804B 35
  • 84.78 (n)
  • 75.58 (a)
ZNF804B 36
  • 75 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF804B 35
  • 84.24 (n)
  • 76.02 (a)
ZNF804B 36
  • 74 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp804b 35
  • 77.84 (n)
  • 68.11 (a)
Zfp804b 16
Zfp804b 36
  • 66 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF804B 35
  • 98.74 (n)
  • 97.63 (a)
ZNF804B 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp804b 35
  • 76.35 (n)
  • 66.17 (a)
oppossum
(Monodelphis domestica)
Mammalia ZNF804B 36
  • 49 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF804B 35
  • 60.35 (n)
  • 47.1 (a)
ZNF804B 36
  • 38 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF804B 36
  • 37 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii znf804b 36
  • 22 (a)
OneToOne
Species with no ortholog for ZNF804B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF804B Gene

ENSEMBL:
Gene Tree for ZNF804B (if available)
TreeFam:
Gene Tree for ZNF804B (if available)

Paralogs for ZNF804B Gene

Paralogs for ZNF804B Gene

genes like me logo Genes that share paralogs with ZNF804B: view

Variants for ZNF804B Gene

Sequence variations from dbSNP and Humsavar for ZNF804B Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1916830 - 89,333,725(+) TGATT(A/G)TAACA reference, missense
rs10487075 - 89,335,707(+) CTTCA(A/G)AAACC reference, missense
rs6963781 - 89,336,295(+) TAAGC(A/G)TGCAT reference, missense
rs801841 - 89,336,565(+) CAACC(A/G)TACAG reference, missense
rs801840 - 89,334,882(+) CTAGG(A/T)TTAAA reference, missense

Structural Variations from Database of Genomic Variants (DGV) for ZNF804B Gene

Variant ID Type Subtype PubMed ID
nsv515995 CNV Gain+Loss 19592680
esv2752187 CNV Gain 17911159
esv2752188 CNV Gain 17911159
nsv831054 CNV Gain 17160897
nsv888697 CNV Loss 21882294
nsv464626 CNV Gain 19166990
dgv7385n71 CNV Loss 21882294
esv2579632 CNV Deletion 19546169
nsv888701 CNV Loss 21882294
dgv7386n71 CNV Loss 21882294
nsv831055 CNV Loss 17160897
esv1612109 CNV Insertion 17803354
esv2734786 CNV Deletion 23290073
esv1580714 CNV Insertion 17803354
nsv888703 CNV Loss 21882294
esv7198 OTHER Inversion 19470904
esv27626 CNV Gain 19812545
nsv888705 CNV Gain 21882294
dgv7387n71 CNV Loss 21882294
dgv2116e1 CNV Complex 17122850
nsv888707 CNV Loss 21882294
esv2667313 CNV Deletion 23128226
esv33064 CNV Loss 17666407
nsv464627 CNV Loss 19166990
esv2674153 CNV Deletion 23128226
nsv888709 CNV Gain 21882294
nsv5829 CNV Insertion 18451855
nsv888710 CNV Loss 21882294
nsv888711 CNV Loss 21882294
nsv888712 CNV Loss 21882294
nsv365593 CNV Loss 16902084
esv1007484 CNV Insertion 20482838
nsv366862 CNV Insertion 16902084
nsv831056 CNV Loss 17160897
dgv7388n71 CNV Loss 21882294
nsv464629 CNV Loss 19166990
esv2678151 CNV Deletion 23128226
esv1248186 CNV Insertion 17803354
nsv818535 CNV Loss 17921354
nsv888716 CNV Loss 21882294
esv28076 CNV Loss 19812545
esv259464 OTHER Complex 20981092
esv24052 CNV Gain+Loss 19812545
nsv888717 CNV Loss 21882294
esv2659894 CNV Deletion 23128226
dgv7389n71 CNV Loss 21882294

Variation tolerance for ZNF804B Gene

Residual Variation Intolerance Score: 98.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.04; 87.51% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF804B Gene

HapMap Linkage Disequilibrium report
ZNF804B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF804B Gene

Disorders for ZNF804B Gene

Relevant External Links for ZNF804B

Genetic Association Database (GAD)
ZNF804B
Human Genome Epidemiology (HuGE) Navigator
ZNF804B
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF804B

No disorders were found for ZNF804B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF804B Gene

Publications for ZNF804B Gene

  1. Novel associations for hypothyroidism include known autoimmune risk loci. (PMID: 22493691) Eriksson N. … Do C.B. (PLoS ONE 2012) 3 48 67
  2. Genome-wide association study of HPV-associated cervical cancer in Japanese women. (PMID: 24700089) Miura K. … Yoshiura K. (J. Med. Virol. 2014) 3
  3. A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus. (PMID: 25130324) Cai D.C. … Hagoort P. (Genes Brain Behav. 2014) 3
  4. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. (PMID: 23382691) Lauc G. … Rudan I. (PLoS Genet. 2013) 3
  5. LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. (PMID: 23443559) Fogeron M.L. … Lange B.M. (Nat Commun 2013) 3

Products for ZNF804B Gene

Sources for ZNF804B Gene

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