ZNF804B Gene
protein-coding GIFtS: 43
GCID: GC07P088388
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zinc finger protein 804B(Previous name: zinc finger 804B )
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Aliases
for ZNF804B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 804B1 2 | | Zinc Finger 804B1 2 | | FLJ321101 |
Export aliases for ZNF804B gene to outside databasesPrevious GC identifers: GC07P088227 GC07P082997 |
Summaries
for ZNF804B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ZNF804B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079595.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF804B gene promoter:
STAT1 Egr-1 STAT1beta MyoD Nkx2-5 STAT1alpha Egr-4 FOXJ2 (long isoform) FOXJ2 ATF
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF804B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF804B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q21.13 Ensembl cytogenetic band: 7q21.13 HGNC cytogenetic band: 7q21.13ZNF804B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P088388: view genomic region
(about GC identifiers)
Start:
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88,388,682 bp from pter |
End:
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88,966,346 bp from pter |
Size:
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577,665 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 87,719,860-88,297,487 |
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Proteins
for ZNF804B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: Z804B_HUMAN, A4D1E1 (See
protein sequence)Recommended Name: Zinc finger protein 804B Size: 1349 amino acids; 152573 Da
Secondary accessions: B2RTV2 Q7Z714 Q96MN7Explore the universe of human proteins at neXtProt for ZNF804B: NX_A4D1E1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A4D1E1
ZNF804B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_857597.1
ENSEMBL proteins: ENSP00000329638 Reactome Protein details: A4D1E1
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ZNF804B for ontologies About GeneDecksing
ZNF804B Antibody Products:
Assay Products for ZNF804B: |
Protein
Domains /
Families
for ZNF804B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF804B for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry A4D1E1ProtoNet protein and cluster: A4D1E1 UniProtKB/Swiss-Prot: Z804B_HUMAN, A4D1E1Similarity: Contains 1 C2H2-type zinc finger |
Function
for ZNF804B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF804B (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF804B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF804B (NM_181646) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF804B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF804B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF804B |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008270 | zinc ion binding |
IEA | -- |
ZNF804B for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF804B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF804B
ZNF804B for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF804B
|
Drugs & Compounds
for ZNF804B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF804B
Search CenterWatch for drugs/clinical trials and news about ZNF804B / Z804B
|
Transcripts
for ZNF804B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF804B gene: NM_181646.2 Unigene Cluster for ZNF804B: Zinc finger protein 804B Hs.684410 [show with all ESTs]Unigene Representative Sequence: BC1408261 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000333190(uc011khi.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF804B (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF804B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF804B (NM_181646) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF804B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF804B |
Additional cDNA sequence: AK056672.1 AY295769.1 BC140826.1 BC140829.1 1 DOTS entry: DT.95331634 3 AceView cDNA sequences: NM_181646 AY295769 AK056672
GeneLoc Exon Structure
|
Expression
for ZNF804B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF804B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAGAGGGAAA
About this image
See ZNF804B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF804B
SOURCE GeneReport for Unigene cluster: Hs.684410
SABiosciences Custom PCR Arrays for ZNF804B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF804B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF804B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF804B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF804B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF804B |
Orthologs
for ZNF804B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ZNF804B gene from 5/15 species (see all 15) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ZNF804B1 |
zinc finger protein 804B |
61.74(n)
49.82(a) |
|
420539 XM_418641.2 XP_418641.2 |
lizard
(Anolis carolinensis) |
Reptilia |
ZNF804B6 |
-- |
39(a) |
1 ↔ 1 |
6(20033053-20063295) |
zebrafish
(Danio rerio) |
Actinopterygii |
znf804b6 |
zinc finger protein 804B |
23(a) |
1 ↔ 1 |
16(30046870-30232440) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G266106 |
D111/G-patch domain-containing protein |
12(a) |
1 → many |
5(9375183-9377125) |
rice
(Oryza sativa) |
Liliopsida |
-- |
G-patch domain containing protein, expressed |
9(a) |
1 → many |
4(904391-908965) |
ENSEMBL Gene Tree for ZNF804B (if available)
TreeFam Gene Tree for ZNF804B (if available) |
Paralogs
for ZNF804B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF804B gene
- GPATCH82 ZNF804A2
ZNF804B for paralogs About GeneDecksing
|
Genomic Variants
for ZNF804B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF804B (88388682 - 88638682 bp, first 250kb of ZNF804B)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 12 variations for ZNF804B
10 CNVs: 100020 8573 10201 69994 8572 52305 2703 7653 64881 64882
1 Indel: 52307
1 Inversion: 59842 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF804B |
|
Disorders
/ Diseases
for ZNF804B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF804B for disorders About GeneDecksing
1  disease for ZNF804B: About MalaCardsanorexia nervosa
Human Genome Epidemiology (HuGE) Navigator: ZNF804B (3 documents)
Export disorders for ZNF804B gene to outside databases
|
Publications
for ZNF804B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF804B gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with ZNF804B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Novel associations for hypothyroidism include known au toimmune risk loci. (PubMed id 22493691)1 Eriksson N....Do C.B. (2012)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- A genome-wide association study on common SNPs and ra re CNVs in anorexia nervosa. (PubMed id 21079607)1 Wang K....Hakonarson H. (2010)
- Genome-Wide Association Study of Anthropometric Trait s and Evidence of Interactions With Age and Study Year in Filipino Women. (PubMed id 20966902)1 Croteau-Chonka D.C....Mohlke K.L. (2010)
- A Japanese-specific allele in the GALNT11 gene. (PubMed id 20547088)1 Yuasa I....Henke J. (2010)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)2 Scherer S.W.... Tsui L.-C. (2003)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)2 Hillier L.W.... Wilson R.K. (2003)
|
External Searches for ZNF804B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF804B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF804B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF804B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF804B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF804B gene:
Search GeneIP for patents involving ZNF804B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF804B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF804B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF804B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF804B | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF804B | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF804B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF804B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF804B | | OriGene Custom Protein Services for ZNF804B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF804B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF804B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF804B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF804B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF804B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF804B |
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| | | | Search Tocris compounds for ZNF804B |
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 | | | ZNF804B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF804B |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF804B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF804B |
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