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Aliases for ZNF80 Gene

Aliases for ZNF80 Gene

  • Zinc Finger Protein 80 2 3
  • ZNFPT17 3 4
  • Zinc Finger Protein 80 (PT17) 2
  • PT17 3

External Ids for ZNF80 Gene

Summaries for ZNF80 Gene

GeneCards Summary for ZNF80 Gene

ZNF80 (Zinc Finger Protein 80) is a Protein Coding gene. Diseases associated with ZNF80 include endogenous depression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF460.

UniProtKB/Swiss-Prot for ZNF80 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF80 Gene

Genomics for ZNF80 Gene

Genomic Location for ZNF80 Gene

Start:
114,234,523 bp from pter
End:
114,237,578 bp from pter
Size:
3,056 bases
Orientation:
Minus strand

Genomic View for ZNF80 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF80 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF80 Gene

Regulatory Elements for ZNF80 Gene

Proteins for ZNF80 Gene

  • Protein details for ZNF80 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P51504-ZNF80_HUMAN
    Recommended name:
    Zinc finger protein 80
    Protein Accession:
    P51504
    Secondary Accessions:
    • Q6NSW4
    • Q6NT14

    Protein attributes for ZNF80 Gene

    Size:
    273 amino acids
    Molecular mass:
    31224 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF80 Gene

Proteomics data for ZNF80 Gene at MOPED

Post-translational modifications for ZNF80 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF80 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF80 Gene

Domains for ZNF80 Gene

Gene Families for ZNF80 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF80 Gene

UniProtKB/Swiss-Prot:

ZNF80_HUMAN
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • P51504
Similarity:
  • Contains 7 C2H2-type zinc fingers.:
    • P51504
genes like me logo Genes that share domains with ZNF80: view

Function for ZNF80 Gene

Molecular function for ZNF80 Gene

GENATLAS Biochemistry: zinc finger protein 80,driven by solitary LTR of ERV9 family
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF80 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF80: view

Phenotypes for ZNF80 Gene

GenomeRNAi human phenotypes for ZNF80:
genes like me logo Genes that share phenotypes with ZNF80: view

miRNA for ZNF80 Gene

miRTarBase miRNAs that target ZNF80

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF80 Gene

Localization for ZNF80 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF80 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF80 Gene COMPARTMENTS Subcellular localization image for ZNF80 gene
Compartment Confidence
nucleus 5
cytosol 2
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for ZNF80 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF80: view

Pathways for ZNF80 Gene

SuperPathways for ZNF80 Gene

No Data Available

Interacting Proteins for ZNF80 Gene

Gene Ontology (GO) - Biological Process for ZNF80 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF80: view

No data available for Pathways by source for ZNF80 Gene

Transcripts for ZNF80 Gene

mRNA/cDNA for ZNF80 Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF80 Gene

Zinc finger protein 80:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF80 Gene

No ASD Table

Relevant External Links for ZNF80 Gene

GeneLoc Exon Structure for
ZNF80
ECgene alternative splicing isoforms for
ZNF80

Expression for ZNF80 Gene

mRNA expression in normal human tissues for ZNF80 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF80 Gene

This gene is overexpressed in Whole Blood (8.3), Spleen (7.9), and Small Intestine - Terminal Ileum (7.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF80 Gene

SOURCE GeneReport for Unigene cluster for ZNF80 Gene Hs.271079

genes like me logo Genes that share expressions with ZNF80: view

Orthologs for ZNF80 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF80 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF80 36
  • 98.29 (n)
  • 96.34 (a)
ZNF80 37
  • 95 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 25 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii CU138542.3 37
  • 25 (a)
ManyToMany
si:dkey-7j22.3 37
  • 31 (a)
ManyToMany
Species with no ortholog for ZNF80:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF80 Gene

ENSEMBL:
Gene Tree for ZNF80 (if available)
TreeFam:
Gene Tree for ZNF80 (if available)

Paralogs for ZNF80 Gene

Paralogs for ZNF80 Gene

Selected SIMAP similar genes for ZNF80 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF80: view

Variants for ZNF80 Gene

Sequence variations from dbSNP and Humsavar for ZNF80 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1047040 -- 114,236,052(-) GGCCC(A/T)CATCA utr-variant-3-prime, nc-transcript-variant
rs1047041 -- 114,236,043(-) CAGTC(A/G)ACGTC utr-variant-3-prime, nc-transcript-variant
rs1047046 -- 114,235,005(-) CGCTG(C/G)AGTTT utr-variant-3-prime, nc-transcript-variant
rs1047048 -- 114,234,875(-) CAAAA(C/G)ATCTC utr-variant-3-prime, nc-transcript-variant
rs1394015 -- 114,239,384(+) CGGGG(C/G)GACCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF80 Gene

Variant ID Type Subtype PubMed ID
nsv519379 CNV Loss 19592680

Relevant External Links for ZNF80 Gene

HapMap Linkage Disequilibrium report
ZNF80

Disorders for ZNF80 Gene

(1) MalaCards Diseases for ZNF80 Gene

Search for ZNF80 Gene in MalaCards »

(1) University of Copenhagen DISEASES for ZNF80 Gene

genes like me logo Genes that share disorders with ZNF80: view

No data available for UniProtKB/Swiss-Prot for ZNF80 Gene

Publications for ZNF80 Gene

  1. Chromosomal localization of four human zinc finger cDNAs. (PMID: 8478004) Huebner K. … Lania L. (Hum. Genet. 1993) 2 3 4
  2. Characterization and genomic mapping of the ZNF80 locus: expression of this zinc-finger gene is driven by a solitary LTR of ERV9 endogenous retroviral family. (PMID: 7659503) di Cristofano A. … la Mantia G. (Nucleic Acids Res. 1995) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. A cohesin-RAD21 interactome. (PMID: 22145905) Panigrahi A.K. … Pati D. (Biochem. J. 2012) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for ZNF80 Gene

Sources for ZNF80 Gene

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