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Aliases for ZNF80 Gene

Aliases for ZNF80 Gene

  • Zinc Finger Protein 80 2 3
  • ZNFPT17 3 4
  • Zinc Finger Protein 80 (PT17) 2
  • PT17 3

External Ids for ZNF80 Gene

Previous GeneCards Identifiers for ZNF80 Gene

  • GC03M110734
  • GC03M113524
  • GC03M115234
  • GC03M115274
  • GC03M115263
  • GC03M115431
  • GC03M113953
  • GC03M111327

Summaries for ZNF80 Gene

GeneCards Summary for ZNF80 Gene

ZNF80 (Zinc Finger Protein 80) is a Protein Coding gene. An important paralog of this gene is ZNF460.

UniProtKB/Swiss-Prot for ZNF80 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF80 Gene

Genomics for ZNF80 Gene

Regulatory Elements for ZNF80 Gene

Genomic Location for ZNF80 Gene

Chromosome:
3
Start:
114,234,631 bp from pter
End:
114,237,578 bp from pter
Size:
2,948 bases
Orientation:
Minus strand

Genomic View for ZNF80 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF80 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF80 Gene

Proteins for ZNF80 Gene

  • Protein details for ZNF80 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P51504-ZNF80_HUMAN
    Recommended name:
    Zinc finger protein 80
    Protein Accession:
    P51504
    Secondary Accessions:
    • Q6NSW4
    • Q6NT14

    Protein attributes for ZNF80 Gene

    Size:
    273 amino acids
    Molecular mass:
    31224 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF80 Gene

Proteomics data for ZNF80 Gene at MOPED

Post-translational modifications for ZNF80 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF80 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF80 Gene

Domains & Families for ZNF80 Gene

Gene Families for ZNF80 Gene

Protein Domains for ZNF80 Gene

Suggested Antigen Peptide Sequences for ZNF80 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P51504

UniProtKB/Swiss-Prot:

ZNF80_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 7 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 7 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF80: view

Function for ZNF80 Gene

Molecular function for ZNF80 Gene

GENATLAS Biochemistry:
zinc finger protein 80,driven by solitary LTR of ERV9 family
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF80 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF80: view
genes like me logo Genes that share phenotypes with ZNF80: view

Animal Model Products

CRISPR Products

miRNA for ZNF80 Gene

miRTarBase miRNAs that target ZNF80

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF80 Gene

Localization for ZNF80 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF80 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF80 Gene COMPARTMENTS Subcellular localization image for ZNF80 gene
Compartment Confidence
nucleus 3
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for ZNF80 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF80: view

Pathways & Interactions for ZNF80 Gene

SuperPathways for ZNF80 Gene

No Data Available

Interacting Proteins for ZNF80 Gene

Gene Ontology (GO) - Biological Process for ZNF80 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF80: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF80 Gene

Drugs & Compounds for ZNF80 Gene

No Compound Related Data Available

Transcripts for ZNF80 Gene

mRNA/cDNA for ZNF80 Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF80 Gene

Zinc finger protein 80:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF80

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF80 Gene

No ASD Table

Relevant External Links for ZNF80 Gene

GeneLoc Exon Structure for
ZNF80
ECgene alternative splicing isoforms for
ZNF80

Expression for ZNF80 Gene

mRNA expression in normal human tissues for ZNF80 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF80 Gene

This gene is overexpressed in Whole Blood (x8.3), Spleen (x7.9), and Small Intestine - Terminal Ileum (x7.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF80 Gene



SOURCE GeneReport for Unigene cluster for ZNF80 Gene Hs.271079

genes like me logo Genes that share expression patterns with ZNF80: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF80 Gene

Orthologs for ZNF80 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF80 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF80 35
  • 98.29 (n)
  • 96.34 (a)
ZNF80 36
  • 95 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 25 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii CU138542.3 36
  • 25 (a)
ManyToMany
si:dkey-7j22.3 36
  • 31 (a)
ManyToMany
Species with no ortholog for ZNF80:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF80 Gene

ENSEMBL:
Gene Tree for ZNF80 (if available)
TreeFam:
Gene Tree for ZNF80 (if available)

Paralogs for ZNF80 Gene

Paralogs for ZNF80 Gene

(538) SIMAP similar genes for ZNF80 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF80: view

Variants for ZNF80 Gene

Sequence variations from dbSNP and Humsavar for ZNF80 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1047040 -- 114,236,052(-) GGCCC(A/T)CATCA utr-variant-3-prime
rs1047041 -- 114,236,043(-) CAGTC(A/G)ACGTC utr-variant-3-prime
rs1047046 -- 114,235,005(-) CGCTG(C/G)AGTTT utr-variant-3-prime
rs1047048 -- 114,234,875(-) CAAAA(C/G)ATCTC utr-variant-3-prime
rs1394015 -- 114,239,384(+) CGGGG(C/G)GACCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF80 Gene

Variant ID Type Subtype PubMed ID
nsv519379 CNV Loss 19592680

Variation tolerance for ZNF80 Gene

Residual Variation Intolerance Score: 86.64% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.04; 50.37% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF80 Gene

HapMap Linkage Disequilibrium report
ZNF80

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF80 Gene

Disorders for ZNF80 Gene

Relevant External Links for ZNF80

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF80
genes like me logo Genes that share disorders with ZNF80: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF80 Gene

Publications for ZNF80 Gene

  1. Chromosomal localization of four human zinc finger cDNAs. (PMID: 8478004) Huebner K. … Lania L. (Hum. Genet. 1993) 2 67
  2. A cohesin-RAD21 interactome. (PMID: 22145905) Panigrahi A.K. … Pati D. (Biochem. J. 2012) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67
  5. Characterization and genomic mapping of the ZNF80 locus: expression of this zinc-finger gene is driven by a solitary LTR of ERV9 endogenous retroviral family. (PMID: 7659503) di Cristofano A. … la Mantia G. (Nucleic Acids Res. 1995) 67

Products for ZNF80 Gene

Sources for ZNF80 Gene

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