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Aliases for ZNF793 Gene

Aliases for ZNF793 Gene

  • Zinc Finger Protein 793 2 3 5

External Ids for ZNF793 Gene

Previous GeneCards Identifiers for ZNF793 Gene

  • GC19P042690
  • GC19P037997
  • GC19P034448

Summaries for ZNF793 Gene

GeneCards Summary for ZNF793 Gene

ZNF793 (Zinc Finger Protein 793) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZIM3.

UniProtKB/Swiss-Prot for ZNF793 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF793 Gene

Genomics for ZNF793 Gene

Regulatory Elements for ZNF793 Gene

Enhancers for ZNF793 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G037973 1.9 FANTOM5 Ensembl ENCODE dbSUPER 80.2 +472.1 472120 10.0 HDGF PKNOX1 WRNIP1 DMAP1 YBX1 ZNF2 YY1 CBX5 ZNF143 ZNF207 ZNF585B ZNF793 ZNF585A ZNF607 ZNF420 ZNF781 ENSG00000267152 ZNF573 ZNF383 WDR87
GH19G038191 1.2 dbSUPER 80 +688.4 688386 6.2 DMAP1 FEZF1 YY1 SLC30A9 ZNF263 SP3 GLIS1 RCOR2 NR2C1 KDM1A ZNF585B ZNF793 ZNF383 ZNF571 ZNF607 ZNF781 ENSG00000267152 ZNF573 SIPA1L3 LINC01535
GH19G037370 1.1 ENCODE 86.7 -135.5 -135464 1.8 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 CBX5 ZNF383 ZNF567 ZNF585B ZNF793 ZNF345 ZNF850 ZNF571 ZNF790-AS1 ZNF529 ZNF461
GH19G037930 1.9 FANTOM5 Ensembl ENCODE dbSUPER 49.4 +431.9 431871 16.0 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 YY1 SLC30A9 CBX5 ZNF143 ZNF793 ZNF607 LINC01535 ZNF585B ZNF781 ZNF585A ENSG00000267152 ZNF420 WDR87 LOC100631378
GH19G037778 1.2 ENCODE 72.1 +272.9 272949 2.1 CREB3L1 DMAP1 FEZF1 YY1 ZNF416 ZNF143 ZNF548 SP3 ZNF610 GLIS1 ZNF793 ZNF383 ZNF345 ZNF585B ZNF781 LINC01535 ZNF607 ZNF790-AS1 ZNF571 ZNF585A
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF793 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF793 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000109169 354 2000 PKNOX1 SIN3A ZNF2 YY1 ZNF302 ZNF416 ZNF143 ZNF548 FOS SP3

Transcription factor binding sites by QIAGEN in the ZNF793 gene promoter:

Genomic Location for ZNF793 Gene

Chromosome:
19
Start:
37,506,447 bp from pter
End:
37,548,762 bp from pter
Size:
42,316 bases
Orientation:
Plus strand

Genomic View for ZNF793 Gene

Genes around ZNF793 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF793 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF793 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF793 Gene

Proteins for ZNF793 Gene

  • Protein details for ZNF793 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZN11-ZN793_HUMAN
    Recommended name:
    Zinc finger protein 793
    Protein Accession:
    Q6ZN11
    Secondary Accessions:
    • E9PGN4
    • Q7Z3Q9

    Protein attributes for ZNF793 Gene

    Size:
    406 amino acids
    Molecular mass:
    46927 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAD97772.1; Type=Frameshift; Positions=291; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF793 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF793 Gene

Post-translational modifications for ZNF793 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF793 Gene

Domains & Families for ZNF793 Gene

Gene Families for ZNF793 Gene

Protein Domains for ZNF793 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF793 Gene

Graphical View of Domain Structure for InterPro Entry

Q6ZN11

UniProtKB/Swiss-Prot:

ZN793_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF793: view

Function for ZNF793 Gene

Molecular function for ZNF793 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF793 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF793: view
genes like me logo Genes that share phenotypes with ZNF793: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF793 Gene

Localization for ZNF793 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF793 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF793 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF793 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF793: view

Pathways & Interactions for ZNF793 Gene

SuperPathways for ZNF793 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF793: view

Pathways by source for ZNF793 Gene

2 Reactome pathways for ZNF793 Gene

Interacting Proteins for ZNF793 Gene

Gene Ontology (GO) - Biological Process for ZNF793 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF793: view

No data available for SIGNOR curated interactions for ZNF793 Gene

Transcripts for ZNF793 Gene

Unigene Clusters for ZNF793 Gene

Zinc finger protein 793:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF793 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c
SP1:
SP2: -

Relevant External Links for ZNF793 Gene

GeneLoc Exon Structure for
ZNF793
ECgene alternative splicing isoforms for
ZNF793

Expression for ZNF793 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF793 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF793 Gene:

ZNF793

SOURCE GeneReport for Unigene cluster for ZNF793 Gene:

Hs.568010

Evidence on tissue expression from TISSUES for ZNF793 Gene

  • Nervous system(4.1)
  • Eye(4)
genes like me logo Genes that share expression patterns with ZNF793: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF793 Gene

Orthologs for ZNF793 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF793 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF793 34 35
  • 99.01 (n)
cow
(Bos Taurus)
Mammalia ZNF793 34 35
  • 87.18 (n)
dog
(Canis familiaris)
Mammalia ZNF793 35
  • 87 (a)
OneToOne
Species where no ortholog for ZNF793 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF793 Gene

ENSEMBL:
Gene Tree for ZNF793 (if available)
TreeFam:
Gene Tree for ZNF793 (if available)

Paralogs for ZNF793 Gene

Paralogs for ZNF793 Gene

(456) SIMAP similar genes for ZNF793 Gene using alignment to 7 proteins:

Pseudogenes.org Pseudogenes for ZNF793 Gene

genes like me logo Genes that share paralogs with ZNF793: view

Variants for ZNF793 Gene

Sequence variations from dbSNP and Humsavar for ZNF793 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000017433 -- 37,514,750(+) TCTTA(C/T)GAATG intron-variant
rs1000071103 -- 37,515,185(+) TAGAT(A/G)AAATA intron-variant
rs1000079874 -- 37,511,079(+) TTTTT(A/T)TATTA intron-variant
rs1000138370 -- 37,507,817(+) TTGTA(C/G)TTACT intron-variant, upstream-variant-2KB
rs1000154539 -- 37,524,279(+) ACCAA(C/T)ATGTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF793 Gene

Variant ID Type Subtype PubMed ID
esv2758759 CNV loss 17122850
esv3583375 CNV loss 25503493
esv3583376 CNV loss 25503493
esv3644288 CNV loss 21293372
nsv1056753 CNV loss 25217958
nsv2478 CNV deletion 18451855
nsv579468 CNV gain 21841781
nsv833819 CNV gain 17160897

Variation tolerance for ZNF793 Gene

Residual Variation Intolerance Score: 62.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.03; 50.17% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF793 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF793

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF793 Gene

Disorders for ZNF793 Gene

Relevant External Links for ZNF793

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF793

No disorders were found for ZNF793 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF793 Gene

Publications for ZNF793 Gene

  1. Methylated B3GAT2 and ZNF793 Are Potential Detection Biomarkers for Barrett's Esophagus. (PMID: 26545406) Yu M. … Grady W.M. (Cancer Epidemiol. Biomarkers Prev. 2015) 3 64
  2. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64

Products for ZNF793 Gene

Sources for ZNF793 Gene

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