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Aliases for ZNF793 Gene

Aliases for ZNF793 Gene

  • Zinc Finger Protein 793 2 3 5

External Ids for ZNF793 Gene

Previous GeneCards Identifiers for ZNF793 Gene

  • GC19P042690
  • GC19P037997
  • GC19P034448

Summaries for ZNF793 Gene

GeneCards Summary for ZNF793 Gene

ZNF793 (Zinc Finger Protein 793) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZIM3.

UniProtKB/Swiss-Prot for ZNF793 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF793 Gene

Genomics for ZNF793 Gene

Regulatory Elements for ZNF793 Gene

Enhancers for ZNF793 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ZNF793 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF793 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Transcription factor binding sites by QIAGEN in the ZNF793 gene promoter:

Genomic Location for ZNF793 Gene

Chromosome:
19
Start:
37,506,447 bp from pter
End:
37,548,762 bp from pter
Size:
42,316 bases
Orientation:
Plus strand

Genomic View for ZNF793 Gene

Genes around ZNF793 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF793 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF793 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF793 Gene

Proteins for ZNF793 Gene

  • Protein details for ZNF793 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZN11-ZN793_HUMAN
    Recommended name:
    Zinc finger protein 793
    Protein Accession:
    Q6ZN11
    Secondary Accessions:
    • E9PGN4
    • Q7Z3Q9

    Protein attributes for ZNF793 Gene

    Size:
    406 amino acids
    Molecular mass:
    46927 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAD97772.1; Type=Frameshift; Positions=291; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF793 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF793 Gene

Post-translational modifications for ZNF793 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF793 Gene

Domains & Families for ZNF793 Gene

Gene Families for ZNF793 Gene

Protein Domains for ZNF793 Gene

Suggested Antigen Peptide Sequences for ZNF793 Gene

Graphical View of Domain Structure for InterPro Entry

Q6ZN11

UniProtKB/Swiss-Prot:

ZN793_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 6 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 6 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF793: view

Function for ZNF793 Gene

Molecular function for ZNF793 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF793 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF793: view
genes like me logo Genes that share phenotypes with ZNF793: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF793 Gene

Localization for ZNF793 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF793 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF793 Gene COMPARTMENTS Subcellular localization image for ZNF793 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF793 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF793: view

Pathways & Interactions for ZNF793 Gene

SuperPathways for ZNF793 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF793: view

Pathways by source for ZNF793 Gene

2 Reactome pathways for ZNF793 Gene

Interacting Proteins for ZNF793 Gene

Gene Ontology (GO) - Biological Process for ZNF793 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF793: view

No data available for SIGNOR curated interactions for ZNF793 Gene

Drugs & Compounds for ZNF793 Gene

No Compound Related Data Available

Transcripts for ZNF793 Gene

Unigene Clusters for ZNF793 Gene

Zinc finger protein 793:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF793 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c
SP1:
SP2: -

Relevant External Links for ZNF793 Gene

GeneLoc Exon Structure for
ZNF793
ECgene alternative splicing isoforms for
ZNF793

Expression for ZNF793 Gene

mRNA expression in normal human tissues for ZNF793 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF793 Gene:

ZNF793

SOURCE GeneReport for Unigene cluster for ZNF793 Gene:

Hs.568010
genes like me logo Genes that share expression patterns with ZNF793: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZNF793 Gene

Orthologs for ZNF793 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF793 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF793 34
  • 87.18 (n)
  • 84.37 (a)
ZNF793 35
  • 83 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF793 34
  • 99.01 (n)
  • 98.52 (a)
ZNF793 35
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF793 35
  • 87 (a)
OneToOne
Species where no ortholog for ZNF793 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF793 Gene

ENSEMBL:
Gene Tree for ZNF793 (if available)
TreeFam:
Gene Tree for ZNF793 (if available)

Paralogs for ZNF793 Gene

Paralogs for ZNF793 Gene

(456) SIMAP similar genes for ZNF793 Gene using alignment to 7 proteins:

Pseudogenes.org Pseudogenes for ZNF793 Gene

genes like me logo Genes that share paralogs with ZNF793: view

Variants for ZNF793 Gene

Sequence variations from dbSNP and Humsavar for ZNF793 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs12977460 - 37,533,369(+) TGGAT(G/T)GGTGA reference, missense, utr-variant-5-prime
rs45593644 - 37,537,055(+) CTTCA(A/G)TCCAG reference, missense
rs3764662 -- 37,517,635(-) AAAGA(A/C/T)GTAGT intron-variant
rs10544049 -- 37,509,621(+) AATAA(-/TAA)GCCAG intron-variant
rs10686444 -- 37,540,283(+) CGTCA(-/A/AA)AAAAA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF793 Gene

Variant ID Type Subtype PubMed ID
esv2758759 CNV loss 17122850
esv3583375 CNV loss 25503493
esv3583376 CNV loss 25503493
esv3644288 CNV loss 21293372
nsv1056753 CNV loss 25217958
nsv2478 CNV deletion 18451855
nsv579468 CNV gain 21841781
nsv833819 CNV gain 17160897

Variation tolerance for ZNF793 Gene

Residual Variation Intolerance Score: 62.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.03; 50.17% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF793 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF793

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF793 Gene

Disorders for ZNF793 Gene

Relevant External Links for ZNF793

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF793

No disorders were found for ZNF793 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF793 Gene

Publications for ZNF793 Gene

  1. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 65
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 65
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 65
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 65
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3 65

Products for ZNF793 Gene

Sources for ZNF793 Gene

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