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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ZNF792 Gene

protein-coding GIFtS: 44
GCID: GC19M035447

zinc finger protein 792

Explore 2 diseases affiliated with
ZNF792 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Zinc Finger Protein 792¹ ²
FLJ38451¹

External Ids:	HGNC: 24751¹	Entrez Gene: 126375²	Ensembl: ENSG00000180884⁷	UniProtKB: Q3KQV3³

Export aliases for ZNF792 gene to outside databases

Previous GC identifers: GC19M040140 GC19M031955

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ZN792_HUMAN, Q3KQV3

Function: May be involved in transcriptional regulation

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000019.9 NC_018930.1 NT_011109.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ZNF792 gene promoter:
HSF2 HTF XBP-1 Evi-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ZNF792 promoter sequence

Search SABiosciences Chromatin IP Primers for ZNF792

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF792

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.11 Ensembl cytogenetic band: 19q13.11 HGNC cytogenetic band: 19q13.11

ZNF792 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF792 gene location

GeneLoc information about chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19M035447: view genomic region (about GC identifiers)

Start:	35,447,258 bp from pter	End:	35,454,953 bp from pter
Size:	7,696 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ZN792_HUMAN, Q3KQV3 (See protein sequence)

Recommended Name: Zinc finger protein 792

Size: 632 amino acids; 71577 Da

Subcellular location: Nucleus (Probable)

Sequence caution: Sequence=AAI01119.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

Sequence=AAI01120.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAI01121.1;

Type=Erroneous initiation; Note=Translation N-terminally extended;

Secondary accessions: B4E333 Q495L1 Q495L3 Q8N932

Explore the universe of human proteins at neXtProt for ZNF792: NX_Q3KQV3

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q3KQV3

ZNF792 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_787068.3

ENSEMBL proteins:

ENSP00000385099

Reactome Protein details: Q3KQV3
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	Uscn Proteins for ZNF792

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

ZNF792 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ZNF792 for domains About GeneDecksing

4 InterPro domains/families:

IPR015880 Znf_C2H2-like

IPR001909 Krueppel-associated_box

IPR013087 Znf_C2H2/integrase_DNA-bd

IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry Q3KQV3

ProtoNet protein and cluster: Q3KQV3

UniProtKB/Swiss-Prot: ZN792_HUMAN, Q3KQV3

Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family

Similarity: Contains 13 C2H2-type zinc fingers

Similarity: Contains 1 KRAB domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: ZN792_HUMAN, Q3KQV3

Function: May be involved in transcriptional regulation

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		hsa-miR-4324 hsa-miR-125a-5p hsa-miR-4251 hsa-miR-551b* hsa-miR-125b hsa-miR-670 hsa-miR-544 hsa-miR-3134

		SwitchGear 3'UTR luciferase reporter plasmid: ZNF792 3' UTR sequence

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Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0008270	zinc ion binding	IEA	--

ZNF792 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Generic Transcription Pathway

Generic Transcription Pathway

1.00

Gene Expression

0.46

Pathway sources
See GeneCards unified pathways
Show all pathways

2 Reactome Pathways for ZNF792

	Generic Transcription Pathway
	Gene Expression

ZNF792 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ZNF792

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--

ZNF792 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ZNF792
Search CenterWatch for drugs/clinical trials and news about ZNF792 / ZN792

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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About This Section

REFSEQ mRNAs for ZNF792 gene:

NM_175872.4

Unigene Cluster for ZNF792:

Zinc finger protein 792

Hs.50405 [show with all ESTs]

Unigene Representative Sequence: NM_175872

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000404801(uc002nxh.1)

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		8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate ZNF792 (see all 11):
		hsa-miR-4324 hsa-miR-125a-5p hsa-miR-4251 hsa-miR-551b* hsa-miR-125b hsa-miR-670 hsa-miR-544 hsa-miR-3134

		SwitchGear 3'UTR luciferase reporter plasmid: ZNF792 3' UTR sequence

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		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF792

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		GenScript: all cDNA clones in your preferred vector: ZNF792 (NM_175872)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF792
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Additional cDNA sequence:

AK095770.1 AK130901.1 AK304550.1 BC101118.1 BC101119.2 BC101120.1

2 DOTS entries:

DT.210976 DT.91994156

24/42 AceView cDNA sequences (see all 42):

AA283757 CR594544 NM_175872 BU754425 N72941 AK095770 Z39872 AI277539

BQ024396 AI472199 W18184 CF146351 BU686719 AW173196 CB108971 AL517806

BX117208 AK130901 AA252229 BI772434 Z43806 BF110071 BG255564 BX451858

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ZNF792 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCCTTTACA

About this image

ZNF792 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See ZNF792 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF792

SOURCE GeneReport for Unigene cluster: Hs.50405

SABiosciences Custom PCR Arrays for ZNF792

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF792

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

--

ENSEMBL Gene Tree for ZNF792 (if available)
TreeFam Gene Tree for ZNF792 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ZNF792 gene

ZNF549² ZNF211² ZNF417² ZNF749² ZNF551² ZNF776² ZNF547² ZNF17²

ZNF416² ZNF548² ZNF304² ZNF587B² ZNF773² ZNF132² ZIK1² ZNF671²

ZNF134² ZNF418² ZNF256² ZNF154² ZNF552² ZNF772² ZNF530² ZNF419²

18/477 SIMAP similar genes for ZNF792 using alignment to 2 protein entries: ZN792_HUMAN (see all proteins) (see all similar genes):

ZNF78L1 ZFS-5 DKFZp686H10254 ZSCAN21 DKFZp686N14223 FLJ00301

HZF36 ZNF24 ZNF3 DKFZp666C237 HZF30 ZFP41

kr-znf3 GLI4 ZFS-4 ZNF232 ZNF436 ZSCAN23

ZNF792 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for ZNF792
PGOHUM00000234288

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs60138746^1,2	F,	--	35446784(+)	`CAACAT/CTGATG`	1	--	ds500¹		1		WA	118
rs188123004^1,2		--	35446930(+)	`GGGGAA/GGGGAA`	1	--	ds500¹		0	--	--	--	--
rs35043444^1,2	C,F,	--	35447093(+)	`GTTAAG/CTATAT`	1	--	ds500¹		8		NA CSA WA EA	366
rs2546023^1,2	C,F,A,H,	--	35447135(+)	`ACCATA/CAAAAA`	1	--	ds500¹		7		NA WA EA	366
rs143509510^1,2		--	35447235(+)	`ATGCTA/GCATGA`	1	--	ds500¹		0	--	--	--	--
rs192875999^1,2		--	35447338(+)	`ATCAAC/TGGTTT`	1	--	ut3¹		0	--	--	--	--
rs184420250^1,2		--	35447361(+)	`AAGGAA/GGGAAT`	1	--	ut3¹		0	--	--	--	--
rs77765640^1,2	C,	--	35447404(+)	`GGATAC/TGTTCA`	1	--	ut3¹		2		CSA WA	120
rs147173519^1,2		--	35447466(+)	`ACTTAC/TCAAAT`	1	--	ut3¹		0	--	--	--	--
rs188794965^1,2		--	35447490(+)	`GCATGA/GCAATC`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ZNF792 (35447258 - 35454953 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF792: --

SABiosciences Cancer Mutation PCR Assays

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ZNF792 for disorders About GeneDecksing

2 diseases for ZNF792: About MalaCards

intrahepatic cholangiocarcinoma cholangiocarcinoma

Human Genome Epidemiology (HuGE) Navigator: ZNF792 (1 document)

Export disorders for ZNF792 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ZNF792 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF792)

Utopia: connect your pdf to the dynamic
world of online information

Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)^{1, 3} Bonaldo M.F.... Soares M.B. (1996)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)¹ Wang A.G....Kim N.S. (2006)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)² Grimwood J.... Lucas S.M. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)² Ota T.... Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 126375	HGNC: 24751	AceView: FLJ38451	Ensembl:ENSG00000180884	euGenes: HUgn126375
ECgene: ZNF792	H-InvDB: ZNF792

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for ZNF792	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ZNF792 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for ZNF792 gene:
Search GeneIP for patents involving ZNF792

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes ZNF792 gene at Home site.

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ZNF792 Gene

zinc finger protein 792

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ZNF792 Gene

zinc finger protein 792

Aliasesfor ZNF792 gene

Summariesfor ZNF792 gene

Genomic Viewsfor ZNF792 gene

Proteinsfor ZNF792 gene

Protein Domains /Familiesfor ZNF792 gene

Functionfor ZNF792 gene

Pathways & Interactionsfor ZNF792 gene

Drugs & Compoundsfor ZNF792 gene

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Expression for ZNF792 gene

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Genome Databases showing ZNF792 gene

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Specialized Databases showing ZNF792 gene

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for ZNF792 gene

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for ZNF792 gene

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for ZNF792 gene

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for ZNF792 gene

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for ZNF792 gene

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for ZNF792 gene

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for ZNF792 gene

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for ZNF792 gene

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for ZNF792 gene

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