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Aliases for ZNF791 Gene

Aliases for ZNF791 Gene

  • Zinc Finger Protein 791 2 3 5

External Ids for ZNF791 Gene

Previous GeneCards Identifiers for ZNF791 Gene

  • GC19P012721
  • GC19P012294

Summaries for ZNF791 Gene

GeneCards Summary for ZNF791 Gene

ZNF791 (Zinc Finger Protein 791) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF14.

UniProtKB/Swiss-Prot for ZNF791 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF791 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF791 Gene

Genomics for ZNF791 Gene

GeneHancer (GH) Regulatory Elements for ZNF791 Gene

Promoters and enhancers for ZNF791 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I012609 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE 564.8 +1.4 1443 4.8 HDGF PKNOX1 SMAD1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 IRF4 ZNF490 ZNF791 PIR37932 ZNF136 ZNF44 ZNF20 ZNF700 ZNF799 ZNF442 ZNF844
GH19I012781 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 82 +178.4 178380 16 CLOCK MLX FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 JUNB CCDC130 ZNF136 ZNF44 ZNF791 ZNF564 WDR83OS TRMT1 ZNF700 TRIR
GH19I013115 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 69.4 +508.0 508018 7.7 DMAP1 YBX1 YY1 ZNF213 E2F8 ZNF143 SP3 NFYC MEF2D ZNF610 TRMT1 NACC1 ZNF791 ZNF136 ZNF442 CCDC130 MRI1 ZNF564 WDR83OS ZNF44
GH19I013148 Promoter/Enhancer 2.9 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 55.5 +542.8 542777 10.2 MLX DMAP1 YBX1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 STX10 ENSG00000267598 IER2 CCDC130 ZNF136 ZNF44 TRMT1 ZNF709 ZNF564 ZNF791
GH19I013011 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 43.3 +409.3 409277 17.2 HDGF FOXA2 MLX ARNT ARID4B FEZF1 DMAP1 ZNF2 YY1 ZNF213 NFIX ZNF136 ZNF709 ZNF791 TRMT1 CCDC130 MRI1 ZNF44 ZNF564 ZNF625
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF791 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZNF791 Gene

Genomic Locations for ZNF791 Gene
chr19:12,610,918-12,633,840
(GRCh38/hg38)
Size:
22,923 bases
Orientation:
Plus strand
chr19:12,721,732-12,742,735
(GRCh37/hg19)

Genomic View for ZNF791 Gene

Genes around ZNF791 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF791 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF791 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF791 Gene

Proteins for ZNF791 Gene

  • Protein details for ZNF791 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q3KP31-ZN791_HUMAN
    Recommended name:
    Zinc finger protein 791
    Protein Accession:
    Q3KP31
    Secondary Accessions:
    • B7Z586
    • Q8NC99

    Protein attributes for ZNF791 Gene

    Size:
    576 amino acids
    Molecular mass:
    66872 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF791 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF791 Gene

Post-translational modifications for ZNF791 Gene

No Post-translational modifications

Other Protein References for ZNF791 Gene

No data available for DME Specific Peptides for ZNF791 Gene

Domains & Families for ZNF791 Gene

Gene Families for ZNF791 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF791 Gene

Suggested Antigen Peptide Sequences for ZNF791 Gene

Graphical View of Domain Structure for InterPro Entry

Q3KP31

UniProtKB/Swiss-Prot:

ZN791_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF791: view

Function for ZNF791 Gene

Molecular function for ZNF791 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF791 Gene

Gene Ontology (GO) - Molecular Function for ZNF791 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF791: view
genes like me logo Genes that share phenotypes with ZNF791: view

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF791 Gene

Localization for ZNF791 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF791 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF791 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF791 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF791: view

Pathways & Interactions for ZNF791 Gene

SuperPathways for ZNF791 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF791: view

Pathways by source for ZNF791 Gene

2 Reactome pathways for ZNF791 Gene

Interacting Proteins for ZNF791 Gene

Gene Ontology (GO) - Biological Process for ZNF791 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF791: view

No data available for SIGNOR curated interactions for ZNF791 Gene

Drugs & Compounds for ZNF791 Gene

No Compound Related Data Available

Transcripts for ZNF791 Gene

Unigene Clusters for ZNF791 Gene

Zinc finger protein 791:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF791 Gene

No ASD Table

Relevant External Links for ZNF791 Gene

GeneLoc Exon Structure for
ZNF791
ECgene alternative splicing isoforms for
ZNF791

Expression for ZNF791 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF791 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF791 Gene



Protein tissue co-expression partners for ZNF791 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF791 Gene:

ZNF791

SOURCE GeneReport for Unigene cluster for ZNF791 Gene:

Hs.720677

Evidence on tissue expression from TISSUES for ZNF791 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with ZNF791: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF791 Gene

Orthologs for ZNF791 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF791 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF791 33 34
  • 99.11 (n)
dog
(Canis familiaris)
Mammalia ZNF791 33 34
  • 80.84 (n)
cow
(Bos Taurus)
Mammalia ZNF791 33 34
  • 80.35 (n)
mouse
(Mus musculus)
Mammalia Zfp791 33 16 34
  • 73.92 (n)
Species where no ortholog for ZNF791 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF791 Gene

ENSEMBL:
Gene Tree for ZNF791 (if available)
TreeFam:
Gene Tree for ZNF791 (if available)

Paralogs for ZNF791 Gene

(551) SIMAP similar genes for ZNF791 Gene using alignment to 7 proteins:

Pseudogenes.org Pseudogenes for ZNF791 Gene

genes like me logo Genes that share paralogs with ZNF791: view

Variants for ZNF791 Gene

Sequence variations from dbSNP and Humsavar for ZNF791 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000134915 -- 12,620,024(+) C/T intron_variant
rs1000362989 -- 12,611,378(+) C/T genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000786455 -- 12,631,551(+) G/A 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1000966271 -- 12,631,849(+) G/A 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1001103957 -- 12,616,043(+) T/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF791 Gene

Variant ID Type Subtype PubMed ID
dgv138n111 CNV deletion 26073780
nsv1160586 CNV duplication 26073780

Variation tolerance for ZNF791 Gene

Residual Variation Intolerance Score: 16.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.40; 8.71% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF791 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF791

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF791 Gene

Disorders for ZNF791 Gene

Additional Disease Information for ZNF791

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for ZNF791 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF791 Gene

Publications for ZNF791 Gene

  1. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  2. Genetic associations of variants in genes encoding HIV-dependency factors required for HIV-1 infection. (PMID: 21083371) Chinn LW … O'Brien SJ (The Journal of infectious diseases 2010) 44 58
  3. Identification of host proteins required for HIV infection through a functional genomic screen. (PMID: 18187620) Brass AL … Elledge SJ (Science (New York, N.Y.) 2008) 3 58
  4. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y … Sugano S (Genome research 2004) 3 58
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 58

Products for ZNF791 Gene

Sources for ZNF791 Gene