ZNF79 Gene
protein-coding GIFtS: 52
GCID: GC09P130186
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zinc finger protein 79(Previous name: zinc finger protein 79 (pT7) )
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Aliases
for ZNF79 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 791 2 | | PT71 | | ZNFpT72 3 | | Zinc Finger Protein 79 (PT7)1 |
Export aliases for ZNF79 gene to outside databasesPrevious GC identifers: GC09P121301 GC09P121833 GC09P123640 GC09P125562 GC09P127266 GC09P129227 GC09P099802 |
Summaries
for ZNF79 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZNF79_HUMAN, Q15937Function: May be involved in transcriptional regulation
Gene Wiki entry for ZNF79
|
Genomic Views
for ZNF79 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008470.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF79 gene promoter:
Elk-1 AP-1 p53 NCX/Ncx HTF GATA-1 GATA-2 PPAR-gamma1 c-Myb PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF79
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF79 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q34 Ensembl cytogenetic band: 9q33.3 HGNC cytogenetic band: 9q34ZNF79 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09P130186: view genomic region
(about GC identifiers)
Start:
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130,186,653 bp from pter |
End:
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130,207,651 bp from pter |
Size:
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20,999 bases |
Orientation:
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plus strand |
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Proteins
for ZNF79 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZNF79_HUMAN, Q15937 (See
protein sequence)Recommended Name: Zinc finger protein 79 Size: 498 amino acids; 55350 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: Q5VVW1 Q96NV1Explore the universe of human proteins at neXtProt for ZNF79: NX_Q15937
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q15937
ZNF79 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_009066.2
ENSEMBL proteins: ENSP00000362446 ENSP00000438418 Reactome Protein details: Q15937
Human Recombinant Protein Products for ZNF79:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF79 for ontologies About GeneDecksing
ZNF79 Antibody Products:
Assay Products for ZNF79: |
Protein
Domains /
Families
for ZNF79 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF79 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q15937ProtoNet protein and cluster: Q15937 2 Blocks protein families: IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZNF79_HUMAN, Q15937Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 11 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF79 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ZNF79_HUMAN, Q15937Function: May be involved in transcriptional regulation Genatlas biochemistry entry for ZNF79:zinc finger protein 79
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
ZNF79 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF79
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF79
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF79 (NM_007135) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF79 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF79 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF79 |
|
Pathways & Interactions
for ZNF79 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF79
ZNF79 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF79
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | | GO:0008150 | biological_process |
ND | -- |
ZNF79 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF79 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF79
Search CenterWatch for drugs/clinical trials and news about ZNF79
|
Transcripts
for ZNF79 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF79 gene: NM_007135.2 Unigene Cluster for ZNF79: Zinc finger protein 79 Hs.522399 [show with all ESTs]Unigene Representative Sequence: NM_0071352 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000342483(uc004bqw.4 uc011maf.2 uc011mag.2) ENST00000543471
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF79
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF79
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF79 (NM_007135) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF79 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF79 |
Additional cDNA sequence: AK054606.1 AK302284.1 AK316233.1 BC062309.1 X65232.1 4 DOTS entries: DT.309987 DT.121170694 DT.121170790 DT.121170788 24/40 AceView cDNA sequences (see all 40): AI439129 BE378801 CB410249 BM556774 AI301044 BP351823 BC062309 AI246642 AA635153 BE799466 AW805424 BX283871 NM_007135 AI700703 BF870852 AA322087 AL041656 AL041655 AA680081 AK054606 AW080350 BE293194 BE219834 AA284829
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF79 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b |
|---|
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| SP1: | | | | | | | - | | - | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | | | | | - | | - | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF79
|
Expression
for ZNF79 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF79 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGTAAAAAA
About this image
See ZNF79 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF79
SOURCE GeneReport for Unigene cluster: Hs.522399
SABiosciences Custom PCR Arrays for ZNF79
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF79
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF79 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF79 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF79 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF79 |
Orthologs
for ZNF79 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZNF79 gene from 4/10 species (see all 10) About this table
Species with no ortholog for ZNF79
ENSEMBL Gene Tree for ZNF79 (if available)
TreeFam Gene Tree for ZNF79 (if available) |
Paralogs
for ZNF79 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF79 gene
- ZNF7132 ZFP69B2 ZNF286A2 ZFP692 ZNF286B2 ZNF3912 ZNF5142
18/545 SIMAP similar genes for ZNF79 using alignment to 2 protein entries: ZNF79_HUMAN (see all proteins)
(see all similar genes):ZNF78L1 ZSCAN31 ZNF818P ZFP41 DKFZp313M0722 ZNF24
ZNF323 ZNF826P kr-znf3 DKFZp686M04222 ZFS-4 ZNF154
ZNF211 ZNF416 ZNF345 DKFZp666C237 HZF30 HZF36
ZNF79 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ZNF79
PGOHUM00000240537
|
Genomic Variants
for ZNF79 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF79 (130186653 - 130207651 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF79: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF79 |
|
Disorders
/ Diseases
for ZNF79 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF79 for disorders About GeneDecksing
OMIM gene information: 194552
OMIM disorders: --
7  diseases for ZNF79: About MalaCardsprostate carcinoma in situ prostate carcinoma vaccinia thyroid cancer
thyroiditis prostatitis carcinoma
1 disease from the University of Copenhagen DISEASES database for ZNF79:Prostate carcinoma in situ Human Genome Epidemiology (HuGE) Navigator: ZNF79 (2 documents)
Export disorders for ZNF79 gene to outside databases
|
Publications
for ZNF79 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF79 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with ZNF79) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Chromosomal localization of four human zinc finger cDNAs. (PubMed id 8478004)1, 2, 3 Huebner K....Lania L. (1993)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)1 Oguri M....Yamada Y. (2010)
- Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)1 Yoshida T....Yamada Y. (2010)
- Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- The zinc finger-associated SCAN box is a conserved oligomerization domain. (PubMed id 10567577)1 Williams A.J....Collins T. (1999)
|
External Searches for ZNF79 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF79 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF79 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF79 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF79 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF79 gene:
Search GeneIP for patents involving ZNF79
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF79 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF79 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF79 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF79 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF79 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF79 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF79 |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF79 |
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