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Aliases for ZNF789 Gene

Aliases for ZNF789 Gene

  • Zinc Finger Protein 789 2 3

External Ids for ZNF789 Gene

Previous GeneCards Identifiers for ZNF789 Gene

  • GC07P098908
  • GC07P099072
  • GC07P093707
  • GC07P099074
  • GC07P099078

Summaries for ZNF789 Gene

GeneCards Summary for ZNF789 Gene

ZNF789 (Zinc Finger Protein 789) is a Protein Coding gene.

UniProtKB/Swiss-Prot for ZNF789 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF789 Gene

Genomics for ZNF789 Gene

Regulatory Elements for ZNF789 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF789 Gene

Start:
99,472,841 bp from pter
End:
99,503,650 bp from pter
Size:
30,810 bases
Orientation:
Plus strand

Genomic View for ZNF789 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF789 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF789 Gene

Proteins for ZNF789 Gene

  • Protein details for ZNF789 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5FWF6-ZN789_HUMAN
    Recommended name:
    Zinc finger protein 789
    Protein Accession:
    Q5FWF6
    Secondary Accessions:
    • A4D282
    • A6NH61
    • Q6ZMZ9

    Protein attributes for ZNF789 Gene

    Size:
    425 amino acids
    Molecular mass:
    49984 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=EAL23876.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF789 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF789 Gene

Proteomics data for ZNF789 Gene at MOPED

Post-translational modifications for ZNF789 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF789 Gene

No data available for DME Specific Peptides for ZNF789 Gene

Domains for ZNF789 Gene

Gene Families for ZNF789 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF789 Gene

Suggested Antigen Peptide Sequences for ZNF789 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5FWF6

UniProtKB/Swiss-Prot:

ZN789_HUMAN :
  • Q5FWF6
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 8 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF789: view

Function for ZNF789 Gene

Molecular function for ZNF789 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF789 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF789: view

Phenotypes for ZNF789 Gene

GenomeRNAi human phenotypes for ZNF789:
genes like me logo Genes that share phenotypes with ZNF789: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF789 Gene

Localization for ZNF789 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF789 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF789 Gene COMPARTMENTS Subcellular localization image for ZNF789 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF789 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus --
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with ZNF789: view

Pathways for ZNF789 Gene

SuperPathways for ZNF789 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF789 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF789: view

No data available for Pathways by source for ZNF789 Gene

Transcripts for ZNF789 Gene

Unigene Clusters for ZNF789 Gene

Zinc finger protein 789:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF789

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF789
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF789 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b
SP1: - - - -
SP2: -
SP3: - - - - -
SP4:
SP5:

Relevant External Links for ZNF789 Gene

GeneLoc Exon Structure for
ZNF789
ECgene alternative splicing isoforms for
ZNF789

Expression for ZNF789 Gene

mRNA expression in normal human tissues for ZNF789 Gene

SOURCE GeneReport for Unigene cluster for ZNF789 Gene Hs.440384

genes like me logo Genes that share expressions with ZNF789: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF789 Gene

Orthologs for ZNF789 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF789 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF789 35
  • 99.53 (n)
  • 99.53 (a)
ZNF789 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF789 35
  • 80 (n)
  • 70.12 (a)
ZNF789 36
  • 70 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF789 35
  • 81.75 (n)
  • 75.83 (a)
ZNF789 36
  • 68 (a)
OneToOne
Species with no ortholog for ZNF789:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF789 Gene

ENSEMBL:
Gene Tree for ZNF789 (if available)
TreeFam:
Gene Tree for ZNF789 (if available)

Paralogs for ZNF789 Gene

Selected SIMAP similar genes for ZNF789 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF789: view

No data available for Paralogs for ZNF789 Gene

Variants for ZNF789 Gene

Sequence variations from dbSNP and Humsavar for ZNF789 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs2272167 -- 99,473,101(-) TACCC(A/C)CCGCA intron-variant
rs6962772 - 99,484,107(+) CGAGA(A/G)CTGGG reference, missense, intron-variant, utr-variant-5-prime
rs10808111 -- 99,473,261(+) ACGCC(A/T)GGACT intron-variant
rs10808112 -- 99,473,365(+) AGTCC(C/T)CTCCA intron-variant
rs13437771 -- 99,473,855(+) acctc(A/G)tgatc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF789 Gene

Variant ID Type Subtype PubMed ID
nsv831069 CNV Loss 17160897

Relevant External Links for ZNF789 Gene

HapMap Linkage Disequilibrium report
ZNF789

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF789 Gene

Disorders for ZNF789 Gene

No disorders were found for ZNF789 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF789 Gene

Publications for ZNF789 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 3
  5. TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells. (PMID: 19850743) Vanderwerf S.M. … Bagby G.C. (Blood 2009) 3

Products for ZNF789 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF789
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF789
    • Block miRNA regulation of ZNF789 using miScript Target Protectors

    Sources for ZNF789 Gene

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