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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF787 Gene

protein-coding   GIFtS: 43
GCID: GC19M056598

zinc finger protein 787
  Search for ZNF787
in
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ZNF787    

Aliases
for ZNF787 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Zinc Finger Protein 7871 2
TTF-I-Interacting Peptide 202 3
TIP202
Transcription Termination Factor I Interacting Peptide 202
TTF-I Interacting Peptide 202

External Ids:    HGNC: 269981   Entrez Gene: 1262082   Ensembl: ENSG000001424097   UniProtKB: Q6DD873   

Export aliases for ZNF787 gene to outside databases

Previous GC identifers: GC19M061291 GC19M052909


Summaries
for ZNF787 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: ZN787_HUMAN, Q6DD87
Function: May be involved in transcriptional regulation




Genomic Views
for ZNF787 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZNF787 gene promoter:
         E2F-3a   E2F-4   Sox5   E2F-5   E2F-2   PPAR-gamma1   E2F-1   E2F   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ZNF787 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZNF787

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF787


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.43   Ensembl cytogenetic band:  19q13.43   HGNC cytogenetic band: 19q13.42

ZNF787 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF787 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M056598:  view genomic region     (about GC identifiers)

Start:
 56,598,732 bp from pter      End:
 56,632,649 bp from pter
Size:
 33,918 bases      Orientation:
 minus strand

Proteins
for ZNF787 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ZN787_HUMAN, Q6DD87 (See protein sequence)
Recommended Name: Zinc finger protein 787  
Size: 382 amino acids; 40428 Da
Subcellular location: Nucleus (Potential)
Sequence caution: Sequence=AAB58413.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: O00455

Explore the universe of human proteins at neXtProt for ZNF787: NX_Q6DD87

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q6DD87

    • ZNF787 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001002836.2  
    ENSEMBL proteins: 
     ENSP00000270459   ENSP00000465647  

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    Uscn Proteins for ZNF787

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--


    ZNF787 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for ZNF787 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ZNF787 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q6DD87

    ProtoNet protein and cluster: Q6DD87

    1 Blocks protein family: IPB007086 C2H2-type zinc finger signature

    UniProtKB/Swiss-Prot: ZN787_HUMAN, Q6DD87
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 7 C2H2-type zinc fingers


    Function
    for ZNF787 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: ZN787_HUMAN, Q6DD87
    Function: May be involved in transcriptional regulation

    miRNA
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    Inhib. RNA
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    Gene Editing
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    Clone
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    Cell Line
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0008270zinc ion binding IEA--


    ZNF787 for ontologies           About GeneDecksing



    Pathways & Interactions
    for ZNF787 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF787

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ZNF787 (Q6DD873 ENSP000002704594) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PTENP604843, ENSP000003610214I2D: score=1 STRING: ENSP00000361021
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--


    ZNF787 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ZNF787 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZNF787
    Search CenterWatch for drugs/clinical trials and news about ZNF787 / ZN787 

    Transcripts
    for ZNF787 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ZNF787 gene: 
    NM_001002836.2  

    Unigene Cluster for ZNF787:

    Zinc finger protein 787
    Hs.397153  [show with all ESTs]
    Unigene Representative Sequence: BC077728
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000270459(uc010eth.1 uc002qml.1) ENST00000586787 ENST00000587279


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    hsa-miR-3184 hsa-miR-423-5p
    SwitchGear 3'UTR luciferase reporter plasmid: ZNF787 3' UTR sequence
    Inhib. RNA
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    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF787
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    Additional cDNA sequence: 

    AF000560.1 BC058034.1 BC077728.1 

    5 DOTS entries:

    DT.442078  DT.100760993  DT.121352101  DT.99938673  DT.99994741 

    24/116 AceView cDNA sequences (see all 116):

    AI373204 BF941806 AI928550 AI923715 AI352619 BM661910 AA557164 AI022401 
    R70344 BC037737 BU732211 AI377107 BM666920 BU751817 BM696130 AI887074 
    AI569651 AI471934 AI563947 AA911726 T82333 AI961741 BU538478 BF594206 

    GeneLoc Exon Structure


    Expression
    for ZNF787 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZNF787 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCGGGCGCGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    ZNF787 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Skeletal MuscleHyoid Arch MusclesMyoblastsSkeletal Muscle
    Skeletal MuscleMandibular Arch MusclesMyoblastsSkeletal Muscle
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See ZNF787 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZNF787

    SOURCE GeneReport for Unigene cluster: Hs.397153
        SABiosciences Custom PCR Arrays for ZNF787
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    In Situ
    Assay Products:     
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for ZNF787

    Orthologs
    for ZNF787 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for ZNF787 gene from 2/10 species (see all 10)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    lizard
    (Anolis carolinensis)    		 Reptilia ZNF4676
    		 --
    		 18(a)
    		 1 → many
    		 GL343790.1(8739-53919)
    fruit fly
    (Drosophila melanogaster)    		 Insecta jim6
    		 jim
    		 11(a)
    		 1 → many
    		 3L(22782333-22828294)


    ENSEMBL Gene Tree for ZNF787 (if available)
    TreeFam Gene Tree for ZNF787 (if available) 

    Paralogs
    for ZNF787 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZNF787 gene
    ZNF7682  ZNF5812  ZNF3582  ZNF5752  ZNF5242  ZNF5802  ZNF702  
    18/292 SIMAP similar genes for ZNF787 using alignment to 3 protein entries:     ZN787_HUMAN (see all proteins) (see all similar genes):
    ZNF78L1    ZNF818P    kr-znf3    ZNF286A    ZNF286B    DKFZp666C237
    GLI4    ZNF514    ZKSCAN1    ZNF22    ZNF232    DKFZp686O111
    ZNF434    ZNF667    ZSCAN32    ZFS-5    ZNF664    ZNF735

    ZNF787 for paralogs           About GeneDecksing



    Genomic Variants
    for ZNF787 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/880 NCBI SNPs in ZNF787 are shown (see all 880)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 19 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs785577931,2
    		F,--56598342(+) ACGTGC/GGCCCT 1 -- ds50011Minor allele frequency- G:0.12WA 118
    rs1445939271,2
    		--56598380(+) GGAGGC/GAGGAG 1 -- ds50010--------
    rs1911880441,2
    		--56598386(+) AGGAGC/GAGGGT 1 -- ds50010--------
    rs616880151,2
    		C,F,--56598437(+) AGGAAG/ACCAGC 1 -- ds50016Minor allele frequency- A:0.35NA WA EA 364
    rs11097131,2
    		--56598442(+) GCCAGC/TCGCCC 1 -- ds50016Minor allele frequency- T:0.42NA MN CSA EA 430
    rs11097141,2
    		--56598448(+) CGCCCC/TTGTGA 1 -- ds50015Minor allele frequency- T:0.25NA MN CSA EA 428
    rs129846291,2
    		C,A,--56598517(+) CAGTCC/TGCCCT 1 -- ds50018Minor allele frequency- T:0.40NA WA EA 368
    rs5262751,2
    		C,A,--56598538(-) GGAGCC/TGCTTG 1 -- ds500110Minor allele frequency- T:0.11MN NA WA CSA EA 437
    rs610360241,2
    		--56598553(+) CCCTGT/GGAGTG 1 -- ds50012Minor allele frequency- G:0.12CSA WA 120
    rs6039441,2
    		C,A,--56598557(+) GTGAGT/CGCCCG 1 -- ds50017Minor allele frequency- C:0.25MN NA CSA WA EA 547

    HapMap Linkage Disequilibrium report for ZNF787 (56598732 - 56632649 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for ZNF787
         2 Indels: 45803 42828

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    Disorders / Diseases
    for ZNF787 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    		   --

    Publications
    for ZNF787 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZNF787 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ZNF787)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    2. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    3. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    4. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)2 Rush J.... Comb M.J. (2005)
    5. Analysis of phosphatase and tensin homolog tumor supp ressor interacting proteins by in vitro and in silico proteomics. (PubMed id 15717329)1 Crockett D.K....Lim M.S. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)

    External Searches for ZNF787 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing ZNF787 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 126208 HGNC: 26998 AceView: LOC126208 Ensembl:ENSG00000142409 euGenes: HUgn126208
    ECgene: ZNF787 H-InvDB: ZNF787

    Other Databases showing ZNF787 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing ZNF787 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZNF787 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for ZNF787 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for ZNF787 gene:
    Search GeneIP for patents involving ZNF787

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for ZNF787 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
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     Browse OriGene Antibodies   OriGene shRNA RFP for ZNF787  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF787   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF787  
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     OriGene siRNA for ZNF787   Browse 3'-UTR reporter clones for miRNA target validation  
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     OriGene Custom Antibody Services for ZNF787   OriGene Custom Protein Services for ZNF787  
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     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF787
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF787
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     GenScript Custom Purified and Recombinant Proteins Services for ZNF787 GenScript cDNA clones with any tag delivered in your preferred vector for ZNF787
     GenScript Custom Assay Services for ZNF787 GenScript Custom Superior Antibodies Services for ZNF787
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     Regulatory tfbs in ZNF787 promoter
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     Browse Sino Biological Proteins and Antibodies
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
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     Search for Antibodies for ZNF787 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for ZNF787
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     ZNF787 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for ZNF787
     Gene Synthesis
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     Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for ZNF787
     SwitchGear 3'UTR luciferase reporter plasmids for ZNF787
     SwitchGear Promoter luciferase reporter plasmids for ZNF787
     Search ThermoFisher Antibodies for ZNF787
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF787
           
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