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Aliases for ZNF787 Gene

Aliases for ZNF787 Gene

  • Zinc Finger Protein 787 2 3 5
  • TTF-I-Interacting Peptide 20 3 4
  • Transcription Termination Factor I Interacting Peptide 20 3
  • TIP20 3

External Ids for ZNF787 Gene

Previous GeneCards Identifiers for ZNF787 Gene

  • GC19M061291
  • GC19M056598
  • GC19M052909

Summaries for ZNF787 Gene

GeneCards Summary for ZNF787 Gene

ZNF787 (Zinc Finger Protein 787) is a Protein Coding gene. An important paralog of this gene is ZNF853.

UniProtKB/Swiss-Prot for ZNF787 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF787 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF787 Gene

Genomics for ZNF787 Gene

GeneHancer (GH) Regulatory Elements for ZNF787 Gene

Promoters and enhancers for ZNF787 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I056117 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 550.8 +1.4 1418 4.8 HDGF PKNOX1 MLX ARID4B SIN3A DMAP1 ZBTB7B YY1 ZNF766 E2F8 ZNF787 U2AF2 ZNF628 ENSG00000267523 ZNF581 ENSG00000267096 ENSG00000223060 GC19M056096 GC19P056014
GH19I056122 Enhancer 0.2 dbSUPER 550.8 -1.9 -1943 1 ZNF787 ENSG00000279959 GC19M056096 GC19P056014
GH19I056124 Enhancer 1.1 ENCODE dbSUPER 0.8 -4.6 -4552 3.3 HDAC1 PKNOX1 ATF1 TAF9B ARNT ZBTB40 TCF12 GATA2 SIRT6 FOS ENSG00000279959 U2AF2 ZNF787 GC19M056096 GC19P056014
GH19I056104 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +11.4 11382 10.7 HDGF FOXA2 PKNOX1 MLX ARID4B SIN3A DMAP1 ZNF2 ZNF48 GLIS2 ZNF865 EPN1 ENSG00000223060 ZNF787 GC19M056096 GC19P056014
GH19I056089 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +29.8 29782 3.4 PKNOX1 NFIB KLF17 SIN3A FEZF1 IRF4 BRCA1 RFX5 RCOR1 FOS NLRP5 NLRP11 ZSCAN5A NLRP8 ENSG00000223060 LINC01864 ZNF787 GC19P056014
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF787 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF787 gene promoter:

Genomic Locations for ZNF787 Gene

Genomic Locations for ZNF787 Gene
chr19:56,087,363-56,121,373
(GRCh38/hg38)
Size:
34,011 bases
Orientation:
Minus strand
chr19:56,598,732-56,632,649
(GRCh37/hg19)

Genomic View for ZNF787 Gene

Genes around ZNF787 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF787 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF787 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF787 Gene

Proteins for ZNF787 Gene

  • Protein details for ZNF787 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6DD87-ZN787_HUMAN
    Recommended name:
    Zinc finger protein 787
    Protein Accession:
    Q6DD87
    Secondary Accessions:
    • O00455

    Protein attributes for ZNF787 Gene

    Size:
    383 amino acids
    Molecular mass:
    40543 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAB58413.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for ZNF787 Gene

Post-translational modifications for ZNF787 Gene

No Post-translational modifications

Other Protein References for ZNF787 Gene

No data available for DME Specific Peptides for ZNF787 Gene

Domains & Families for ZNF787 Gene

Gene Families for ZNF787 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF787 Gene

Suggested Antigen Peptide Sequences for ZNF787 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6DD87

UniProtKB/Swiss-Prot:

ZN787_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF787: view

Function for ZNF787 Gene

Molecular function for ZNF787 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF787 Gene

Gene Ontology (GO) - Molecular Function for ZNF787 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF787: view
genes like me logo Genes that share phenotypes with ZNF787: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF787 Gene

Localization for ZNF787 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF787 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF787 gene
Compartment Confidence
nucleus 5
mitochondrion 2
endoplasmic reticulum 2
cytosol 2
golgi apparatus 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Mitochondria (2)
  • Nucleoli (2)
  • Nucleus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF787 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF787: view

Pathways & Interactions for ZNF787 Gene

SuperPathways for ZNF787 Gene

No Data Available

Interacting Proteins for ZNF787 Gene

Selected Interacting proteins: Q6DD87-ZN787_HUMAN for ZNF787 Gene via IID

Gene Ontology (GO) - Biological Process for ZNF787 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF787: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF787 Gene

Drugs & Compounds for ZNF787 Gene

No Compound Related Data Available

Transcripts for ZNF787 Gene

Unigene Clusters for ZNF787 Gene

Zinc finger protein 787:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF787 Gene

No ASD Table

Relevant External Links for ZNF787 Gene

GeneLoc Exon Structure for
ZNF787
ECgene alternative splicing isoforms for
ZNF787

Expression for ZNF787 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF787 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF787 Gene

This gene is overexpressed in Whole Blood (x4.7).

Protein differential expression in normal tissues from HIPED for ZNF787 Gene

This gene is overexpressed in Lung (22.5), Peripheral blood mononuclear cells (8.6), Retina (7.9), and Monocytes (6.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF787 Gene



Protein tissue co-expression partners for ZNF787 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF787 Gene:

ZNF787

SOURCE GeneReport for Unigene cluster for ZNF787 Gene:

Hs.397153

Evidence on tissue expression from TISSUES for ZNF787 Gene

  • Liver(4.1)
  • Lung(4.1)
  • Pancreas(4.1)
genes like me logo Genes that share expression patterns with ZNF787: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF787 Gene

Orthologs for ZNF787 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF787 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF787 33 34
  • 92.67 (n)
dog
(Canis familiaris)
Mammalia ZNF787 33 34
  • 91.19 (n)
mouse
(Mus musculus)
Mammalia Zfp787 33 16 34
  • 85.74 (n)
rat
(Rattus norvegicus)
Mammalia Zfp787 33
  • 85.21 (n)
zebrafish
(Danio rerio)
Actinopterygii ZNF787 34
  • 34 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta pho 34
  • 7 (a)
ManyToMany
phol 34
  • 6 (a)
ManyToMany
Species where no ortholog for ZNF787 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF787 Gene

ENSEMBL:
Gene Tree for ZNF787 (if available)
TreeFam:
Gene Tree for ZNF787 (if available)

Paralogs for ZNF787 Gene

Paralogs for ZNF787 Gene

(234) SIMAP similar genes for ZNF787 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF787: view

Variants for ZNF787 Gene

Sequence variations from dbSNP and Humsavar for ZNF787 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs202243737 uncertain-significance, Oromandibular-limb hypogenesis spectrum 56,088,086(-) C/G coding_sequence_variant, missense_variant
rs1000075019 -- 56,087,734(-) C/G 3_prime_UTR_variant
rs1000214491 -- 56,112,197(-) A/G genic_upstream_transcript_variant, intron_variant
rs1000228939 -- 56,116,063(-) T/C genic_upstream_transcript_variant, intron_variant
rs1000293411 -- 56,122,175(-) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF787 Gene

Variant ID Type Subtype PubMed ID
dgv206n21 CNV loss 19592680
dgv207n21 CNV loss 19592680
dgv3680n100 CNV gain 25217958
dgv3681n100 CNV gain 25217958
dgv544e201 CNV deletion 23290073
esv1002478 CNV insertion 20482838
esv1007685 CNV insertion 20482838
esv1027952 CNV insertion 17803354
esv1322949 CNV deletion 17803354
esv2064147 CNV deletion 18987734
esv2657534 CNV deletion 23128226
esv2719010 CNV deletion 23290073
esv2719013 CNV deletion 23290073
esv2719015 CNV deletion 23290073
esv2719016 CNV deletion 23290073
esv2719018 CNV deletion 23290073
esv2719019 CNV deletion 23290073
esv3348405 CNV insertion 20981092
esv3431520 CNV insertion 20981092
esv3644857 CNV loss 21293372
esv4826 CNV loss 18987735
esv991692 CNV deletion 20482838
nsv1057820 CNV gain 25217958
nsv1072900 CNV deletion 25765185
nsv1143927 CNV deletion 24896259
nsv580354 CNV gain 21841781
nsv833883 CNV loss 17160897
nsv952151 CNV deletion 24416366

Variation tolerance for ZNF787 Gene

Gene Damage Index Score: 1.23; 24.67% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF787 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF787

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF787 Gene

Disorders for ZNF787 Gene

Additional Disease Information for ZNF787

No disorders were found for ZNF787 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF787 Gene

Publications for ZNF787 Gene

  1. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  2. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  3. The central role of EED in the orchestration of polycomb group complexes. (PMID: 24457600) Cao Q … Chinnaiyan AM (Nature communications 2014) 3 58
  4. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y … Zou H (Journal of proteomics 2014) 4 58
  5. Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6. (PMID: 23151878) Evsyukova I … Garcia-Blanco MA (RNA (New York, N.Y.) 2013) 3 58

Products for ZNF787 Gene

Sources for ZNF787 Gene

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