Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF787 Gene

Aliases for ZNF787 Gene

  • Zinc Finger Protein 787 2 3 5
  • TTF-I-Interacting Peptide 20 3 4
  • Transcription Termination Factor I Interacting Peptide 20 3
  • TIP20 3

External Ids for ZNF787 Gene

Previous GeneCards Identifiers for ZNF787 Gene

  • GC19M061291
  • GC19M056598
  • GC19M052909

Summaries for ZNF787 Gene

GeneCards Summary for ZNF787 Gene

ZNF787 (Zinc Finger Protein 787) is a Protein Coding gene. An important paralog of this gene is ZEB2.

UniProtKB/Swiss-Prot for ZNF787 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF787 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF787 Gene

Genomics for ZNF787 Gene

Regulatory Elements for ZNF787 Gene

Enhancers for ZNF787 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H056117 1.4 ENCODE dbSUPER 0.7 +1.4 1418 4.8 HDGF PKNOX1 MLX ARID4B SIN3A DMAP1 ZBTB7B YY1 ZNF766 ZNF207 U2AF2 ZNF628 ENSG00000267523 ZNF581 ENSG00000267096 SSC5D ZNF787 ENSG00000223060
GH19H056124 1.2 ENCODE dbSUPER 0.7 -4.6 -4553 3.3 HDAC1 TBP PKNOX1 ATF1 ARNT ZBTB40 TCF12 GATA2 SIRT6 FOS U2AF2 ZNF787 ENSG00000279959
GH19H056104 1.8 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +11.4 11383 10.7 HDGF FOXA2 PKNOX1 MLX ARID4B SIN3A DMAP1 ZNF2 GLIS2 ZNF143 ZNF865 EPN1 ENSG00000223060 ZNF787
GH19H056116 0.4 dbSUPER 0.7 +4.3 4314 0.9 POLR2A ZNF623 ZNF787 ENSG00000223060
GH19H056122 0.2 dbSUPER 0.7 -1.9 -1943 1 ZNF787 ENSG00000279959
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF787 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF787 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000111719 373 2001 HDGF PKNOX1 MLX ARID4B SIN3A DMAP1 ZBTB7B YY1 ZNF766 ZNF207

Genomic Locations for ZNF787 Gene

Genomic Locations for ZNF787 Gene
chr19:56,087,363-56,121,373
(GRCh38/hg38)
Size:
34,011 bases
Orientation:
Minus strand
chr19:56,598,732-56,632,649
(GRCh37/hg19)

Genomic View for ZNF787 Gene

Genes around ZNF787 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF787 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF787 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF787 Gene

Proteins for ZNF787 Gene

  • Protein details for ZNF787 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6DD87-ZN787_HUMAN
    Recommended name:
    Zinc finger protein 787
    Protein Accession:
    Q6DD87
    Secondary Accessions:
    • O00455

    Protein attributes for ZNF787 Gene

    Size:
    383 amino acids
    Molecular mass:
    40543 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAB58413.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for ZNF787 Gene

Post-translational modifications for ZNF787 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF787 Gene

No data available for DME Specific Peptides for ZNF787 Gene

Domains & Families for ZNF787 Gene

Gene Families for ZNF787 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF787 Gene

Suggested Antigen Peptide Sequences for ZNF787 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6DD87

UniProtKB/Swiss-Prot:

ZN787_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF787: view

Function for ZNF787 Gene

Molecular function for ZNF787 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF787 Gene

Gene Ontology (GO) - Molecular Function for ZNF787 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF787: view
genes like me logo Genes that share phenotypes with ZNF787: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF787 Gene

Localization for ZNF787 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF787 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF787 gene
Compartment Confidence
nucleus 5
mitochondrion 2
endoplasmic reticulum 2
cytosol 2
golgi apparatus 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Mitochondria (2)
  • Nucleoli (2)
  • Nucleus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF787 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF787: view

Pathways & Interactions for ZNF787 Gene

SuperPathways for ZNF787 Gene

No Data Available

Interacting Proteins for ZNF787 Gene

Selected Interacting proteins: Q6DD87-ZN787_HUMAN for ZNF787 Gene via IID

Gene Ontology (GO) - Biological Process for ZNF787 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF787: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF787 Gene

Drugs & Compounds for ZNF787 Gene

No Compound Related Data Available

Transcripts for ZNF787 Gene

mRNA/cDNA for ZNF787 Gene

Unigene Clusters for ZNF787 Gene

Zinc finger protein 787:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF787 Gene

No ASD Table

Relevant External Links for ZNF787 Gene

GeneLoc Exon Structure for
ZNF787
ECgene alternative splicing isoforms for
ZNF787

Expression for ZNF787 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF787 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF787 Gene

This gene is overexpressed in Whole Blood (x4.7).

Protein differential expression in normal tissues from HIPED for ZNF787 Gene

This gene is overexpressed in Lung (22.5), Peripheral blood mononuclear cells (8.6), Retina (7.9), and Monocytes (6.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ZNF787 Gene



Protein tissue co-expression partners for ZNF787 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF787 Gene:

ZNF787

SOURCE GeneReport for Unigene cluster for ZNF787 Gene:

Hs.397153

Evidence on tissue expression from TISSUES for ZNF787 Gene

  • Liver(4.1)
  • Lung(4.1)
  • Pancreas(4.1)
genes like me logo Genes that share expression patterns with ZNF787: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF787 Gene

Orthologs for ZNF787 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF787 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF787 33 34
  • 92.67 (n)
dog
(Canis familiaris)
Mammalia ZNF787 33 34
  • 91.19 (n)
mouse
(Mus musculus)
Mammalia Zfp787 33 16 34
  • 85.74 (n)
rat
(Rattus norvegicus)
Mammalia Zfp787 33
  • 85.21 (n)
zebrafish
(Danio rerio)
Actinopterygii ZNF787 34
  • 34 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta pho 34
  • 7 (a)
ManyToMany
phol 34
  • 6 (a)
ManyToMany
Species where no ortholog for ZNF787 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF787 Gene

ENSEMBL:
Gene Tree for ZNF787 (if available)
TreeFam:
Gene Tree for ZNF787 (if available)

Paralogs for ZNF787 Gene

Paralogs for ZNF787 Gene

(234) SIMAP similar genes for ZNF787 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF787: view

Variants for ZNF787 Gene

Sequence variations from dbSNP and Humsavar for ZNF787 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs202243737 Uncertain significance 56,088,086(+) TCGTC(C/G)TCCTC reference, missense
rs1000075019 -- 56,087,734(+) GTCGC(C/G)ACTCG utr-variant-3-prime
rs1000214491 -- 56,112,197(+) TCCCT(A/G)GGAGA intron-variant
rs1000228939 -- 56,116,063(+) GGCTG(C/T)GTCGG intron-variant
rs1000293411 -- 56,122,175(+) AAAAA(A/G)CACAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF787 Gene

Variant ID Type Subtype PubMed ID
nsv952151 CNV deletion 24416366
nsv833883 CNV loss 17160897
nsv580354 CNV gain 21841781
nsv1143927 CNV deletion 24896259
nsv1072900 CNV deletion 25765185
nsv1057820 CNV gain 25217958
esv991692 CNV deletion 20482838
esv4826 CNV loss 18987735
esv3644857 CNV loss 21293372
esv3431520 CNV insertion 20981092
esv3348405 CNV insertion 20981092
esv2719019 CNV deletion 23290073
esv2719018 CNV deletion 23290073
esv2719016 CNV deletion 23290073
esv2719015 CNV deletion 23290073
esv2719013 CNV deletion 23290073
esv2719010 CNV deletion 23290073
esv2657534 CNV deletion 23128226
esv2064147 CNV deletion 18987734
esv1322949 CNV deletion 17803354
esv1027952 CNV insertion 17803354
esv1007685 CNV insertion 20482838
esv1002478 CNV insertion 20482838
dgv544e201 CNV deletion 23290073
dgv3681n100 CNV gain 25217958
dgv3680n100 CNV gain 25217958
dgv207n21 CNV loss 19592680
dgv206n21 CNV loss 19592680

Variation tolerance for ZNF787 Gene

Gene Damage Index Score: 1.23; 24.67% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF787 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF787

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF787 Gene

Disorders for ZNF787 Gene

Relevant External Links for ZNF787

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF787

No disorders were found for ZNF787 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF787 Gene

Publications for ZNF787 Gene

  1. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  2. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 60
  3. The central role of EED in the orchestration of polycomb group complexes. (PMID: 24457600) Cao Q … Chinnaiyan AM (Nature communications 2014) 3 60
  4. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y … Zou H (Journal of proteomics 2014) 4 60
  5. Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6. (PMID: 23151878) Evsyukova I … Garcia-Blanco MA (RNA (New York, N.Y.) 2013) 3 60

Products for ZNF787 Gene

Sources for ZNF787 Gene

Content
Loading form....