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Aliases for ZNF786 Gene

Aliases for ZNF786 Gene

  • Zinc Finger Protein 786 2 3 5

External Ids for ZNF786 Gene

Previous GeneCards Identifiers for ZNF786 Gene

  • GC07M148397
  • GC07M148088
  • GC07M148766
  • GC07M142845

Summaries for ZNF786 Gene

GeneCards Summary for ZNF786 Gene

ZNF786 (Zinc Finger Protein 786) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF425.

UniProtKB/Swiss-Prot for ZNF786 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF786 Gene

Genomics for ZNF786 Gene

Regulatory Elements for ZNF786 Gene

Promoters for ZNF786 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF786 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF786 Gene

Chromosome:
7
Start:
149,069,641 bp from pter
End:
149,090,782 bp from pter
Size:
21,142 bases
Orientation:
Minus strand

Genomic View for ZNF786 Gene

Genes around ZNF786 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF786 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF786 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF786 Gene

Proteins for ZNF786 Gene

  • Protein details for ZNF786 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N393-ZN786_HUMAN
    Recommended name:
    Zinc finger protein 786
    Protein Accession:
    Q8N393
    Secondary Accessions:
    • A1A568
    • B4DMI1

    Protein attributes for ZNF786 Gene

    Size:
    782 amino acids
    Molecular mass:
    89815 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF786 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF786 Gene

Proteomics data for ZNF786 Gene at MOPED

Post-translational modifications for ZNF786 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF786 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF786 Gene

Domains & Families for ZNF786 Gene

Gene Families for ZNF786 Gene

Protein Domains for ZNF786 Gene

Suggested Antigen Peptide Sequences for ZNF786 Gene

Graphical View of Domain Structure for InterPro Entry

Q8N393

UniProtKB/Swiss-Prot:

ZN786_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 16 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 16 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF786: view

Function for ZNF786 Gene

Molecular function for ZNF786 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF786: view

Animal Model Products

CRISPR Products

miRNA for ZNF786 Gene

miRTarBase miRNAs that target ZNF786

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF786 Gene

Localization for ZNF786 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF786 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF786 Gene COMPARTMENTS Subcellular localization image for ZNF786 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF786 Gene

Pathways & Interactions for ZNF786 Gene

SuperPathways for ZNF786 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF786: view

Pathways by source for ZNF786 Gene

2 Reactome pathways for ZNF786 Gene

Interacting Proteins for ZNF786 Gene

Gene Ontology (GO) - Biological Process for ZNF786 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF786: view

No data available for SIGNOR curated interactions for ZNF786 Gene

Drugs & Compounds for ZNF786 Gene

No Compound Related Data Available

Transcripts for ZNF786 Gene

mRNA/cDNA for ZNF786 Gene

Unigene Clusters for ZNF786 Gene

Zinc finger protein 786:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF786 Gene

No ASD Table

Relevant External Links for ZNF786 Gene

GeneLoc Exon Structure for
ZNF786
ECgene alternative splicing isoforms for
ZNF786

Expression for ZNF786 Gene

mRNA expression in normal human tissues for ZNF786 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF786 Gene



SOURCE GeneReport for Unigene cluster for ZNF786 Gene Hs.729572

genes like me logo Genes that share expression patterns with ZNF786: view

Protein tissue co-expression partners for ZNF786 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF786 Gene

Orthologs for ZNF786 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF786 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia ZNF425 35
  • 79.68 (n)
  • 71.45 (a)
ZNF786 36
  • 70 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp786 35
  • 74.42 (n)
  • 66.41 (a)
Zfp786 16
Zfp786 36
  • 64 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF786 35
  • 98.98 (n)
  • 98.47 (a)
ZNF786 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp786 35
  • 74.47 (n)
  • 65.62 (a)
cow
(Bos Taurus)
Mammalia ZNF786 36
  • 61 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 40 (a)
ManyToMany
Species with no ortholog for ZNF786:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF786 Gene

ENSEMBL:
Gene Tree for ZNF786 (if available)
TreeFam:
Gene Tree for ZNF786 (if available)

Paralogs for ZNF786 Gene

Paralogs for ZNF786 Gene

(481) SIMAP similar genes for ZNF786 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF786: view

Variants for ZNF786 Gene

Sequence variations from dbSNP and Humsavar for ZNF786 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1405123 -- 149,082,308(+) AGCAA(C/T)TGGTT intron-variant
rs1405124 -- 149,082,526(+) CCATT(A/G)TTATT intron-variant
rs1534197 -- 149,074,878(+) TCCAG(C/T)TGCCA intron-variant
rs1534198 -- 149,075,231(+) TAAAA(C/T)AATGC intron-variant
rs1358062 -- 149,086,651(+) ACACA(C/T)ACACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF786 Gene

Variant ID Type Subtype PubMed ID
nsv889402 CNV Loss 21882294
esv2666491 CNV Deletion 23128226
esv2668984 CNV Deletion 23128226

Variation tolerance for ZNF786 Gene

Residual Variation Intolerance Score: 5.72% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.57; 30.36% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF786 Gene

HapMap Linkage Disequilibrium report
ZNF786

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF786 Gene

Disorders for ZNF786 Gene

Relevant External Links for ZNF786

Genetic Association Database (GAD)
ZNF786
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF786

No disorders were found for ZNF786 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF786 Gene

Publications for ZNF786 Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 67
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A. … Wiemann S. (Nucleic Acids Res. 2006) 3
  4. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF786 Gene

Sources for ZNF786 Gene

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