ZNF785 Gene
protein-coding GIFtS: 40
GCID: GC16M030590
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|
zinc finger protein 785
| |
Aliases
for ZNF785 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 7851 2 | | FLJ321301 |
Export aliases for ZNF785 gene to outside databasesPrevious GC identifers: GC16M030498 GC16M030008 GC16M028154 |
Summaries
for ZNF785 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN785_HUMAN, A8K8V0Function: May be involved in transcriptional regulation (By similarity)
|
Genomic Views
for ZNF785 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF785 gene promoter:
STAT1 STAT1beta NF-kappaB STAT1alpha CREB deltaCREB STAT3 ZIC2/Zic2 NF-kappaB1 ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF785
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF785 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p11.2 Ensembl cytogenetic band: 16p11.2 HGNC cytogenetic band: 16p11.2ZNF785 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M030590: view genomic region
(about GC identifiers)
Start:
|
30,585,061 bp from pter |
End:
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30,597,092 bp from pter |
Size:
|
12,032 bases |
Orientation:
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minus strand |
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Proteins
for ZNF785 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN785_HUMAN, A8K8V0 (See
protein sequence)Recommended Name: Zinc finger protein 785 Size: 405 amino acids; 46168 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: O75701 Q8IW91 Q8WV14 Q96MN0Alternative splicing: 2 isoforms: A8K8V0-1 A8K8V0-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZNF785: NX_A8K8V0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A8K8V0
ZNF785 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_689671.2
ENSEMBL proteins: ENSP00000456097 ENSP00000420340 ENSP00000378642 ENSP00000458511
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF785 for ontologies About GeneDecksing
ZNF785 Antibody Products:
Assay Products for ZNF785: |
Protein
Domains /
Families
for ZNF785 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF785 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry A8K8V0ProtoNet protein and cluster: A8K8V0 UniProtKB/Swiss-Prot: ZN785_HUMAN, A8K8V0Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 7 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF785 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN785_HUMAN, A8K8V0Function: May be involved in transcriptional regulation (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF785
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF785
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for ZNF785 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF785 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF785 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF785 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for ZNF785:
|
Pathways & Interactions
for ZNF785 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF785
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF785 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF785 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF785
Search CenterWatch for drugs/clinical trials and news about ZNF785 / ZN785
|
Transcripts
for ZNF785 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF785 gene: NM_152458.6 Unigene Cluster for ZNF785: Zinc finger protein 785 Hs.513509 [show with all ESTs]Unigene Representative Sequence: NM_1524584 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000562128 ENST00000470110(uc002dyv.2) ENST00000395216(uc002dyw.2 uc010vez.2)
ENST00000567773
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF785
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF785
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF785 (NM_152458) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF785 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF785 |
Additional cDNA sequence: AK309511.1 BC040642.2 6 DOTS entries: DT.456418 DT.111480 DT.95353439 DT.95365947 DT.86839031 DT.97775105 24/36 AceView cDNA sequences (see all 36): AI283029 W01951 AI918488 CB989423 AA427747 AI004601 AF086220 AK056692 AI680525 BE265745 AW273256 AI160875 AW043743 AW969032 BQ212320 AI375066 AI144506 BE145750 AI114543 BC040642 BG699137 AI268498 W32566 CB054315
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF785 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c |
|---|
|
| SP1: | | | | | | | | | - | | | | - | | - | | | | | | | | |
| SP2: | | | | | - | | - | | - | | | | - | | - | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | | | | | | |
ECgene alternative splicing isoforms for ZNF785
|
Expression
for ZNF785 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF785 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
Genevestigator expression for ZNF785
SOURCE GeneReport for Unigene cluster: Hs.513509
SABiosciences Custom PCR Arrays for ZNF785
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF785
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF785 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF785 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF785 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF785 |
Orthologs
for ZNF785 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF785 (if available)
TreeFam Gene Tree for ZNF785 (if available) |
Paralogs
for ZNF785 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF785 gene
- ZNF7642 ZNF7472 ZNF6882 ENSG000002614592 ENSG000002608692 ZNF6892
18/289 SIMAP similar genes for ZNF785 using alignment to 3 protein entries: ZN785_HUMAN (see all proteins)
(see all similar genes):ZNF688 ZNF695 ZNF707 ZFS-6 ZNF213 ZNF790
ZNF ZNF271 ZNF519 kr-znf3 ZNF324 ZNF814
DKFZp434G1930 ZNF214 ZNF551 ZNF420 ZNF658 ZNF793
ZNF785 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF785 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF785 (30585061 - 30597092 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF785: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF785 |
|
Disorders
/ Diseases
for ZNF785 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZNF785 for disorders About MalaCards
ZNF785 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: ZNF785 (1 document)
Export disorders for ZNF785 gene to outside databases
|
Publications
for ZNF785 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF785 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF785) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PubMed id 10493829)1, 3 Loftus B.J.... Adams M.D. (1999)
- Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF785 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF785 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF785 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF785 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF785 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF785 gene:
Search GeneIP for patents involving ZNF785
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF785 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | Browse OriGene 29mer shRNA kits in GFP-retroviral vector | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF785 | | | OriGene Protein Over-expression Lysate for ZNF785 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF785 | | OriGene 3'-UTR Clone for ZNF785 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF785 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF785 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF785 | | OriGene Custom Protein Services for ZNF785 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF785 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF785 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF785 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF785 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF785 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF785 |
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 | | | ZNF785 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF785 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF785 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF785 |
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