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Aliases for ZNF785 Gene

Aliases for ZNF785 Gene

  • Zinc Finger Protein 785 2 3 5

External Ids for ZNF785 Gene

Previous GeneCards Identifiers for ZNF785 Gene

  • GC16M030498
  • GC16M030008
  • GC16M028154

Summaries for ZNF785 Gene

GeneCards Summary for ZNF785 Gene

ZNF785 (Zinc Finger Protein 785) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF764.

UniProtKB/Swiss-Prot for ZNF785 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF785 Gene

Genomics for ZNF785 Gene

Regulatory Elements for ZNF785 Gene

Promoters for ZNF785 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF785 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF785 Gene

Chromosome:
16
Start:
30,573,219 bp from pter
End:
30,586,421 bp from pter
Size:
13,203 bases
Orientation:
Minus strand

Genomic View for ZNF785 Gene

Genes around ZNF785 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF785 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF785 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF785 Gene

Proteins for ZNF785 Gene

  • Protein details for ZNF785 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8K8V0-ZN785_HUMAN
    Recommended name:
    Zinc finger protein 785
    Protein Accession:
    A8K8V0
    Secondary Accessions:
    • O75701
    • Q8IW91
    • Q8WV14
    • Q96MN0

    Protein attributes for ZNF785 Gene

    Size:
    405 amino acids
    Molecular mass:
    46168 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF785 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF785 Gene

Proteomics data for ZNF785 Gene at MOPED

Post-translational modifications for ZNF785 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF785 Gene

No data available for DME Specific Peptides for ZNF785 Gene

Domains & Families for ZNF785 Gene

Gene Families for ZNF785 Gene

Protein Domains for ZNF785 Gene

Suggested Antigen Peptide Sequences for ZNF785 Gene

Graphical View of Domain Structure for InterPro Entry

A8K8V0

UniProtKB/Swiss-Prot:

ZN785_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 7 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 7 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF785: view

Function for ZNF785 Gene

Molecular function for ZNF785 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF785: view

Animal Model Products

CRISPR Products

miRNA for ZNF785 Gene

miRTarBase miRNAs that target ZNF785

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF785 Gene

Localization for ZNF785 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF785 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF785 Gene COMPARTMENTS Subcellular localization image for ZNF785 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF785 Gene

Pathways & Interactions for ZNF785 Gene

SuperPathways for ZNF785 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF785: view

Pathways by source for ZNF785 Gene

2 Reactome pathways for ZNF785 Gene

Gene Ontology (GO) - Biological Process for ZNF785 Gene

None

No data available for SIGNOR curated interactions for ZNF785 Gene

Drugs & Compounds for ZNF785 Gene

No Compound Related Data Available

Transcripts for ZNF785 Gene

Unigene Clusters for ZNF785 Gene

Zinc finger protein 785:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF785 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c
SP1: - - -
SP2: - - - - -
SP3: -
SP4: - -
SP5: - -

Relevant External Links for ZNF785 Gene

GeneLoc Exon Structure for
ZNF785
ECgene alternative splicing isoforms for
ZNF785

Expression for ZNF785 Gene

mRNA expression in normal human tissues for ZNF785 Gene

Protein differential expression in normal tissues from HIPED for ZNF785 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF785 Gene



SOURCE GeneReport for Unigene cluster for ZNF785 Gene Hs.513509

genes like me logo Genes that share expression patterns with ZNF785: view

Protein tissue co-expression partners for ZNF785 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF785 Gene

Orthologs for ZNF785 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF785 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF785 35
  • 99.67 (n)
  • 99.51 (a)
ZNF785 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF785 36
  • 46 (a)
OneToOne
ZNF785 35
  • 82.29 (n)
  • 77.19 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 35 (a)
OneToMany
Species with no ortholog for ZNF785:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF785 Gene

ENSEMBL:
Gene Tree for ZNF785 (if available)
TreeFam:
Gene Tree for ZNF785 (if available)

Paralogs for ZNF785 Gene

(278) SIMAP similar genes for ZNF785 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF785: view

Variants for ZNF785 Gene

Sequence variations from dbSNP and Humsavar for ZNF785 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1142115 -- 30,578,781(-) ggcca(A/G)ggtgg intron-variant
rs1142117 -- 30,578,768(-) agatc(A/G)cctga intron-variant
rs1142119 -- 30,578,766(-) atcac(C/T)tgagg intron-variant
rs1142120 -- 30,578,733(-) acgaa(C/T)atgga intron-variant
rs1142134 -- 30,578,625(-) AATCG(C/T)TTGAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF785 Gene

Variant ID Type Subtype PubMed ID
nsv905727 CNV Loss 21882294

Variation tolerance for ZNF785 Gene

Residual Variation Intolerance Score: 75.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.15; 39.03% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF785 Gene

HapMap Linkage Disequilibrium report
ZNF785

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF785 Gene

Disorders for ZNF785 Gene

Relevant External Links for ZNF785

Genetic Association Database (GAD)
ZNF785
Human Genome Epidemiology (HuGE) Navigator
ZNF785
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF785

No disorders were found for ZNF785 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF785 Gene

Publications for ZNF785 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PMID: 10493829) Loftus B.J. … Adams M.D. (Genomics 1999) 2 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3
  5. Identification of host proteins required for HIV infection through a functional genomic screen. (PMID: 18187620) Brass A.L. … Elledge S.J. (Science 2008) 3

Products for ZNF785 Gene

Sources for ZNF785 Gene

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