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Aliases for ZNF784 Gene

Aliases for ZNF784 Gene

  • Zinc Finger Protein 784 2 3 5

External Ids for ZNF784 Gene

Previous GeneCards Identifiers for ZNF784 Gene

  • GC19M060824
  • GC19M056132
  • GC19M052442

Summaries for ZNF784 Gene

GeneCards Summary for ZNF784 Gene

ZNF784 (Zinc Finger Protein 784) is a Protein Coding gene. An important paralog of this gene is ZNF628.

UniProtKB/Swiss-Prot for ZNF784 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF784 Gene

Genomics for ZNF784 Gene

Regulatory Elements for ZNF784 Gene

Enhancers for ZNF784 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G055337 1.8 FANTOM5 ENCODE dbSUPER 2.1 +284.8 284774 4.0 MLX CREB3L1 FEZF1 DMAP1 YY1 ZNF143 ZNF548 ZNF263 SP3 NFYC LENG8-AS1 ENSG00000235681 U2AF2 FAM71E2 KMT5C PPP6R1 ZNF628 TMEM238 IL11 TMEM190
GH19G055626 1.3 Ensembl ENCODE dbSUPER 0.7 -1.8 -1841 0.9 SOX13 FOXA2 SAP130 MAX CEBPG ZSCAN9 EED RELB IKZF2 CREM FIZ1 ZNF524 ZNF628 TMEM86B KIR3DL1 ZNF784 GC19P055633
GH19G055623 1 ENCODE 0.7 +0.1 141 2.0 HDGF ATF1 AGO1 ZNF133 SIN3A YY1 ZNF143 KLF13 SP3 SP5 FIZ1 ZNF524 ZNF628 TMEM86B ZNF580 GC19M055621 ZNF784
GH19G055631 1.2 Ensembl ENCODE 0.4 -7.9 -7877 1.8 FOXA2 ARNT WRNIP1 SIN3A ZNF48 ZNF121 ZNF143 ZNF207 MXD4 REST ZNF580 GC19P055633 ZNF784
GH19G055622 0.4 ENCODE 0.7 +1.6 1602 0.1 BCOR ZMYM3 GC19M055621 ZNF784
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF784 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF784 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000111689 101 1001 HDGF ATF1 AGO1 ZNF133 SIN3A YY1 ZNF143 KLF13 SP3 SP5

Genomic Location for ZNF784 Gene

Chromosome:
19
Start:
55,620,741 bp from pter
End:
55,624,601 bp from pter
Size:
3,861 bases
Orientation:
Minus strand

Genomic View for ZNF784 Gene

Genes around ZNF784 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF784 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF784 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF784 Gene

Proteins for ZNF784 Gene

  • Protein details for ZNF784 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NCA9-ZN784_HUMAN
    Recommended name:
    Zinc finger protein 784
    Protein Accession:
    Q8NCA9

    Protein attributes for ZNF784 Gene

    Size:
    323 amino acids
    Molecular mass:
    34237 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF784 Gene

Post-translational modifications for ZNF784 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF784 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF784 Gene

Domains & Families for ZNF784 Gene

Gene Families for ZNF784 Gene

Protein Domains for ZNF784 Gene

Suggested Antigen Peptide Sequences for ZNF784 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NCA9

UniProtKB/Swiss-Prot:

ZN784_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF784: view

Function for ZNF784 Gene

Molecular function for ZNF784 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF784 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF784: view
genes like me logo Genes that share phenotypes with ZNF784: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF784 Gene

Localization for ZNF784 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF784 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF784 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF784 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF784: view

Pathways & Interactions for ZNF784 Gene

SuperPathways for ZNF784 Gene

No Data Available

Interacting Proteins for ZNF784 Gene

Gene Ontology (GO) - Biological Process for ZNF784 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002244 hematopoietic progenitor cell differentiation IEA --
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF784: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF784 Gene

Transcripts for ZNF784 Gene

mRNA/cDNA for ZNF784 Gene

Unigene Clusters for ZNF784 Gene

Zinc finger protein 784:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF784 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b
SP1: -
SP2:

Relevant External Links for ZNF784 Gene

GeneLoc Exon Structure for
ZNF784
ECgene alternative splicing isoforms for
ZNF784

Expression for ZNF784 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF784 Gene

Protein differential expression in normal tissues from HIPED for ZNF784 Gene

This gene is overexpressed in Fetal ovary (46.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF784 Gene



Protein tissue co-expression partners for ZNF784 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF784 Gene:

ZNF784

SOURCE GeneReport for Unigene cluster for ZNF784 Gene:

Hs.53996

Evidence on tissue expression from TISSUES for ZNF784 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with ZNF784: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF784 Gene

Orthologs for ZNF784 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF784 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF784 34 35
  • 99.48 (n)
dog
(Canis familiaris)
Mammalia ZNF784 34
  • 85.21 (n)
cow
(Bos Taurus)
Mammalia ZNF784 34 35
  • 83.5 (n)
mouse
(Mus musculus)
Mammalia Zfp784 34 16 35
  • 80.89 (n)
rat
(Rattus norvegicus)
Mammalia Zfp865 34
  • 80.39 (n)
zebrafish
(Danio rerio)
Actinopterygii si:dkeyp-2e4.5 35
  • 26 (a)
ManyToMany
si:dkeyp-2e4.2 35
  • 25 (a)
ManyToMany
si:dkeyp-2e4.3 35 35
  • 24 (a)
ManyToMany
si:dkeyp-2e4.6 35
  • 24 (a)
ManyToMany
si:dkeyp-2e4.8 35
  • 24 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.7153 35
  • 17 (a)
OneToMany
Species where no ortholog for ZNF784 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF784 Gene

ENSEMBL:
Gene Tree for ZNF784 (if available)
TreeFam:
Gene Tree for ZNF784 (if available)

Paralogs for ZNF784 Gene

Variants for ZNF784 Gene

Sequence variations from dbSNP and Humsavar for ZNF784 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000123174 -- 55,621,866(+) GGCCT(C/G)CAGAG reference, missense
rs1001025014 -- 55,626,531(+) GTTAT(C/T)GCAAG upstream-variant-2KB
rs1001886274 -- 55,621,198(+) GGTGA(C/T)GGGAT utr-variant-3-prime
rs1002000284 -- 55,620,415(+) GAGTT(C/G)TGTTC downstream-variant-500B
rs1002053975 -- 55,620,608(+) CCCCC(C/G)ATTCT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ZNF784 Gene

Variant ID Type Subtype PubMed ID
nsv828643 CNV loss 20364138
nsv953624 CNV deletion 24416366

Variation tolerance for ZNF784 Gene

Residual Variation Intolerance Score: 78.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.30; 41.11% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF784 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF784

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF784 Gene

Disorders for ZNF784 Gene

Relevant External Links for ZNF784

Genetic Association Database (GAD)
ZNF784
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF784

No disorders were found for ZNF784 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF784 Gene

Publications for ZNF784 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  4. SUMO-2 orchestrates chromatin modifiers in response to DNA damage. (PMID: 25772364) Hendriks I.A. … Vertegaal A.C. (Cell Rep. 2015) 4 64
  5. Uncovering global SUMOylation signaling networks in a site-specific manner. (PMID: 25218447) Hendriks I.A. … Vertegaal A.C. (Nat. Struct. Mol. Biol. 2014) 4 64

Products for ZNF784 Gene

Sources for ZNF784 Gene

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