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Aliases for ZNF783 Gene

Aliases for ZNF783 Gene

  • Zinc Finger Family Member 783 2 3 5

External Ids for ZNF783 Gene

Previous GeneCards Identifiers for ZNF783 Gene

  • GC07P148590
  • GC07P148959

Summaries for ZNF783 Gene

GeneCards Summary for ZNF783 Gene

ZNF783 (Zinc Finger Family Member 783) is a Protein Coding gene. Diseases associated with ZNF783 include Acrodysostosis. GO annotations related to this gene include nucleic acid binding and transcription cofactor activity. An important paralog of this gene is ZNF777.

UniProtKB/Swiss-Prot for ZNF783 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF783 Gene

Genomics for ZNF783 Gene

Regulatory Elements for ZNF783 Gene

Enhancers for ZNF783 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F148939 1.2 Ensembl ENCODE 44.7 -321.1 -321089 3.4 PKNOX1 ARNT CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 FOS ZNF398 ZNF783 ZNF777 ZNF282 ZNF212 ZNF786 ENSG00000271664 LOC155060 ZNF767P EZH2
GH07F149241 0.2 ENCODE 39.4 -20.2 -20178 1.0 ZNF202 FOXK2 ADNP GTF2E2 IRF1 ZBTB33 PRDM10 LOC155060 ZNF783 ENSG00000271664 ZNF212 ZNF398 ZNF282 ZNF777 ZNF767P LOC101928733 GC07P149257
GH07F149261 1 ENCODE 33.3 0.0 -27 2.0 HDGF ATF1 CREB3L1 MLX ARID4B SIN3A FEZF1 DMAP1 BRCA1 GLIS2 ZNF783 LOC155060 ZNF212 ENSG00000271664 ZNF398 ZNF282 ZNF777 ZNF767P PIR51256
GH07F149238 0.2 ENCODE 33.2 -22.2 -22162 2.1 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF143 ZNF783 ZNF398 LOC155060 ENSG00000271664 ZNF212 ZNF786 ZNF282 ZNF777 LOC101928733 GC07P149257
GH07F149143 0.2 ENCODE 30.4 -115.9 -115879 6.5 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A ZNF2 YY1 ZNF143 ZNF207 ZNF282 ZNF786 LOC155060 ZNF212 ZNF783 ZNF425 ZNF398 ENSG00000271664 ZNF777 LOC643438
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ZNF783 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF783 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001564911 129 1801 HDGF ATF1 CREB3L1 MLX ARID4B SIN3A FEZF1 DMAP1 GLIS2 ZNF143

Genomic Location for ZNF783 Gene

Chromosome:
7
Start:
149,262,171 bp from pter
End:
149,297,302 bp from pter
Size:
35,132 bases
Orientation:
Plus strand

Genomic View for ZNF783 Gene

Genes around ZNF783 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF783 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF783 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF783 Gene

Proteins for ZNF783 Gene

  • Protein details for ZNF783 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZMS7-ZN783_HUMAN
    Recommended name:
    Protein ZNF783
    Protein Accession:
    Q6ZMS7
    Secondary Accessions:
    • C9J9J2

    Protein attributes for ZNF783 Gene

    Size:
    281 amino acids
    Molecular mass:
    31422 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF783 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF783 Gene

Post-translational modifications for ZNF783 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF783 Gene

No data available for DME Specific Peptides for ZNF783 Gene

Domains & Families for ZNF783 Gene

Gene Families for ZNF783 Gene

Protein Domains for ZNF783 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF783 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZMS7

UniProtKB/Swiss-Prot:

ZN783_HUMAN :
  • Contains 1 KRAB domain.
Domain:
  • Contains 1 KRAB domain.
genes like me logo Genes that share domains with ZNF783: view

Function for ZNF783 Gene

Molecular function for ZNF783 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF783 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003712 transcription cofactor activity IBA --
GO:0005515 protein binding IPI 25416956
GO:0042802 identical protein binding IPI 25416956
genes like me logo Genes that share ontologies with ZNF783: view

Phenotypes for ZNF783 Gene

GenomeRNAi human phenotypes for ZNF783:
genes like me logo Genes that share phenotypes with ZNF783: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF783 Gene

Localization for ZNF783 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF783 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF783 Gene COMPARTMENTS Subcellular localization image for ZNF783 gene
Compartment Confidence
nucleus 5
cytosol 2
plasma membrane 2

Gene Ontology (GO) - Cellular Components for ZNF783 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA,IBA --
genes like me logo Genes that share ontologies with ZNF783: view

Pathways & Interactions for ZNF783 Gene

SuperPathways for ZNF783 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF783 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006357 regulation of transcription from RNA polymerase II promoter IBA --
genes like me logo Genes that share ontologies with ZNF783: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF783 Gene

Transcripts for ZNF783 Gene

mRNA/cDNA for ZNF783 Gene

(2) REFSEQ mRNAs :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF783 Gene

No ASD Table

Relevant External Links for ZNF783 Gene

GeneLoc Exon Structure for
ZNF783
ECgene alternative splicing isoforms for
ZNF783

Expression for ZNF783 Gene

mRNA expression in normal human tissues for ZNF783 Gene

Protein differential expression in normal tissues from HIPED for ZNF783 Gene

This gene is overexpressed in Neutrophil (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF783 Gene



Protein tissue co-expression partners for ZNF783 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF783 Gene:

ZNF783
genes like me logo Genes that share expression patterns with ZNF783: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF783 Gene

Orthologs for ZNF783 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF783 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF783 34 35
  • 98.53 (n)
cow
(Bos Taurus)
Mammalia ZNF783 34 35
  • 84.14 (n)
dog
(Canis familiaris)
Mammalia ZNF783 34 35
  • 83.55 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 34 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 33 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp956 35
  • 29 (a)
ManyToMany
chicken
(Gallus gallus)
Aves -- 35
  • 25 (a)
ManyToMany
Species where no ortholog for ZNF783 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF783 Gene

ENSEMBL:
Gene Tree for ZNF783 (if available)
TreeFam:
Gene Tree for ZNF783 (if available)

Paralogs for ZNF783 Gene

Paralogs for ZNF783 Gene

genes like me logo Genes that share paralogs with ZNF783: view

Variants for ZNF783 Gene

Sequence variations from dbSNP and Humsavar for ZNF783 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10228007 -- 149,260,961(+) CTGAT(A/G)AGATC upstream-variant-2KB
rs10231256 -- 149,261,012(+) TGTGT(C/T)TTAGA upstream-variant-2KB
rs10237721 -- 149,272,887(+) cccct(C/T)gcacc intron-variant
rs10240897 -- 149,264,216(+) TTACT(A/G)TGATA intron-variant, upstream-variant-2KB
rs10244037 -- 149,264,240(+) TGTTA(C/T)TGAAT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF783 Gene

Variant ID Type Subtype PubMed ID
nsv1024700 CNV loss 25217958
nsv1126814 CNV deletion 24896259
nsv473100 CNV novel sequence insertion 20440878
nsv6001 CNV deletion 18451855

Variation tolerance for ZNF783 Gene

Residual Variation Intolerance Score: 67.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.74; 66.40% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF783 Gene

Human Gene Mutation Database (HGMD)
ZNF783
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF783

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF783 Gene

Disorders for ZNF783 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZNF783 Gene - From: GeneCards

Disorder Aliases PubMed IDs
acrodysostosis
  • acrodysplasia
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for ZNF783

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF783
genes like me logo Genes that share disorders with ZNF783: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF783 Gene

Publications for ZNF783 Gene

  1. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PMID: 19413330) Gauci S. … Mohammed S. (Anal. Chem. 2009) 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. Large-scale concatenation cDNA sequencing. (PMID: 9110174) Yu W. … Gibbs R.A. (Genome Res. 1997) 2 3 64
  4. A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B. … Gibbs R.A. (Anal. Biochem. 1996) 2 3 64
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64

Products for ZNF783 Gene

Sources for ZNF783 Gene

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