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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF782 Gene

protein-coding   GIFtS: 41
GCID: GC09M099578

zinc finger protein 782
  Search for ZNF782
in
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ZNF782    

Aliases
for ZNF782 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Zinc Finger Protein 7821 2
FLJ166361

External Ids:    HGNC: 331101   Entrez Gene: 1584312   Ensembl: ENSG000001965977   UniProtKB: Q6ZMW23   

Export aliases for ZNF782 gene to outside databases

Previous GC identifers: GC09M098619 GC09M069190


Summaries
for ZNF782 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: ZN782_HUMAN, Q6ZMW2
Function: May be involved in transcriptional regulation (By similarity)




Genomic Views
for ZNF782 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_008470.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZNF782 gene promoter:
         HFH-3   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   Evi-1   FOXI1   Nkx6-1   POU2F1a   FOXO1a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ZNF782 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZNF782

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF782


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q22.33   Ensembl cytogenetic band:  9q22.33   HGNC cytogenetic band: 9q22.33

ZNF782 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF782 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M099578:  view genomic region     (about GC identifiers)

Start:
 99,578,754 bp from pter      End:
 99,637,905 bp from pter
Size:
 59,152 bases      Orientation:
 minus strand

Proteins
for ZNF782 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ZN782_HUMAN, Q6ZMW2 (See protein sequence)
Recommended Name: Zinc finger protein 782  
Size: 699 amino acids; 80904 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: B2RNR0

Explore the universe of human proteins at neXtProt for ZNF782: NX_Q6ZMW2

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q6ZMW2

    • ZNF782 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001001662.1  
    ENSEMBL proteins: 
     ENSP00000419397   ENSP00000418686   ENSP00000417577   ENSP00000419978   ENSP00000440624  

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    Uscn Proteins for ZNF782

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--


    ZNF782 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for ZNF782 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ZNF782 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR015880 Znf_C2H2-like
     IPR001909 Krueppel-associated_box
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q6ZMW2

    ProtoNet protein and cluster: Q6ZMW2

    2 Blocks protein families:
    IPB001909 KRAB box
    IPB007086 C2H2-type zinc finger signature


    UniProtKB/Swiss-Prot: ZN782_HUMAN, Q6ZMW2
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 15 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain


    Function
    for ZNF782 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: ZN782_HUMAN, Q6ZMW2
    Function: May be involved in transcriptional regulation (By similarity)

    miRNA
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    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0008270zinc ion binding IEA--


    ZNF782 for ontologies           About GeneDecksing



    Pathways & Interactions
    for ZNF782 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF782

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--


    ZNF782 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ZNF782 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZNF782
    Search CenterWatch for drugs/clinical trials and news about ZNF782 / ZN782 

    Transcripts
    for ZNF782 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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    About This Section
    REFSEQ mRNAs for ZNF782 gene: 
    NM_001001662.1  

    Unigene Cluster for ZNF782:

    Zinc finger protein 782
    Hs.732126  [show with all ESTs]
    Unigene Representative Sequence: AK131468
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000481138(uc004awp.1 uc011lup.1) ENST00000289032 ENST00000466833
    ENST00000478850 ENST00000430274 ENST00000498811 ENST00000485322 ENST00000535338


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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate ZNF782:
    hsa-miR-188-3p hsa-miR-539
    SwitchGear 3'UTR luciferase reporter plasmid: ZNF782 3' UTR sequence
    Inhib. RNA
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AK131468.1 AK302460.1 BC137073.1 

    4 DOTS entries:

    DT.102822336  DT.106579  DT.97778258  DT.97815737 

    24/35 AceView cDNA sequences (see all 35):

    AA019430 NM_001001662 Z21188 AI208312 BQ227337 CB121164 W76661 CR619806 
    BF435209 AA856776 BX089738 BX103276 AA490476 W73073 AK131468 N35244 
    AA490699 AL540705 AV725290 Z44630 CD103090 Z32829 CA390459 BX953109 

    GeneLoc Exon Structure


    Expression
    for ZNF782 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZNF782 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    ZNF782 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Posterior foregut-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See ZNF782 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZNF782

    SOURCE GeneReport for Unigene cluster: Hs.732126
        SABiosciences Custom PCR Arrays for ZNF782
    Primer
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF782

    Orthologs
    for ZNF782 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    		   --

    ENSEMBL Gene Tree for ZNF782 (if available)
    TreeFam Gene Tree for ZNF782 (if available) 

    Paralogs
    for ZNF782 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZNF782 gene
    ZNF3342  ENSG000002673602  ZNF122  ZNF5102  ZNF5672  ZNF33A2  ZNF7172  RBAK2  
    ZNF487P2  ZNF37A2  ZNF2482  ZNF33B2  ZNF3822  
    18/538 SIMAP similar genes for ZNF782 using alignment to 5 protein entries:     ZN782_HUMAN (see all proteins) (see all similar genes):
    HZF16    POM121C    ZNF300P1    ZNF78L1    kr-znf3    HZF36
    ZFS-4    DKFZp686M04222    ZNF436    DKFZp434J0650    ZNF833P    ZNF664
    ZNF    ZNF253    ZNF558    ZNF56    ZNF826P    ZSCAN16

    ZNF782 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ZNF782
    PGOHUM00000236720


    Genomic Variants
    for ZNF782 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/628 NCBI SNPs in ZNF782 are shown (see all 628)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 9 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1462306191,2
    		--99578780(+) TTTTT-/GTTCTT 1 -- ds50010--------
    rs1162272841,2
    		F,--99578987(+) AAATTA/GTCATA 1 -- ds50011Minor allele frequency- G:0.07WA 118
    rs1155527941,2
    		F,--99579011(+) TTTGGG/CTGTGT 1 -- ds50011Minor allele frequency- C:0.03WA 118
    rs1918139141,2
    		--99579033(+) TGTGTC/GTGTGT 1 -- ds50010--------
    rs109791521,2
    		C,F,H,--99579100(+) CTGATG/AAGGAA 1 -- ds500115Minor allele frequency- A:0.09NS EA NA 2124
    rs1496384291,2
    		--99579305(+) CCTCAA/CTGCAA 1 -- ut310--------
    rs1833712751,2
    		--99579344(+) AACTCC/GATGCC 1 -- ut310--------
    rs356326601,2
    		C,--99579369(+) GACCC-/GGGGTT 1 -- ut310--------
    rs674057211,2
    		C--99579370(+) CGGGTG/-TCCTA 1 -- ut311Minor allele frequency- -:0.00NA 2
    rs1866768251,2
    		C,--99579370(+) GACCCA/GGGTTC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for ZNF782 (99578754 - 99637905 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for ZNF782
         2 CNVs: 4646 52897

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    Disorders / Diseases
    for ZNF782 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ZNF782 for disorders           About MalaCards

    ZNF782 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: ZNF782 (1 document)

    Export disorders for ZNF782 gene to outside databases

    Publications
    for ZNF782 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZNF782 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ZNF782)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    3. Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci. (PubMed id 19030899)1 Lei S.F....Deng H.W. (2008)
    4. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    External Searches for ZNF782 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing ZNF782 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 158431 HGNC: 33110 AceView: FLJ16636 Ensembl:ENSG00000196597 euGenes: HUgn158431
    ECgene: ZNF782 H-InvDB: ZNF782

    Other Databases showing ZNF782 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing ZNF782 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZNF782 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for ZNF782 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for ZNF782 gene:
    Search GeneIP for patents involving ZNF782

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for ZNF782 gene

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    About This Section

     
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