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Aliases for ZNF781 Gene

Aliases for ZNF781 Gene

  • Zinc Finger Protein 781 2 3 5

External Ids for ZNF781 Gene

Previous GeneCards Identifiers for ZNF781 Gene

  • GC19M042851
  • GC19M038158
  • GC19M034608

Summaries for ZNF781 Gene

GeneCards Summary for ZNF781 Gene

ZNF781 (Zinc Finger Protein 781) is a Protein Coding gene.

UniProtKB/Swiss-Prot for ZNF781 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF781 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF781 Gene

Genomics for ZNF781 Gene

Regulatory Elements for ZNF781 Gene

Enhancers for ZNF781 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H038647 1.8 FANTOM5 ENCODE dbSUPER 83.5 -967.5 -967471 25 ZFP64 FEZF1 DMAP1 YY1 ZNF143 ZNF548 SP3 ZC3H11A NFYC ZFP41 HNRNPL ZFP30 ZNF781 ZNF573 ZNF607 ENSG00000267152 SUPT5H PAK4 PAF1 PLEKHG2
GH19H037593 1.1 ENCODE 97.1 +97.6 97623 2 PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9 ZNF302 ZNF416 ZNF567 ZNF383 ZNF527 ZNF345 ZFP30 ZNF850 HKR1 ZNF571 ZNF607 ZNF585A
GH19H037653 1.2 ENCODE 82.3 +37.0 37041 2 HDGF PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZNF527 ZNF383 ZNF567 ZNF345 ZNF571 ZFP30 ZNF850 HKR1 ZNF790 ZNF607
GH19H037778 1.1 ENCODE 86 -87.1 -87074 2 PKNOX1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 ZNF766 ZNF302 ZNF416 ZNF345 ZNF383 ZFP30 ZNF527 ZNF781 ZNF585B ZNF571 HKR1 ZNF540 ZNF790
GH19H037370 1.1 ENCODE 62.3 +321.3 321339 1 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 ZNF416 ZNF143 ZNF567 ZNF383 ZNF527 ZNF345 ZNF850 ZNF571 HKR1 ZFP30 ZNF790 ZNF793
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF781 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF781 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000109174 221 1399 ATF1 ARID4B DMAP1 YY1 ZNF143 ATF7 ZHX2 MXD4 NFYC MIER2

Genomic Location for ZNF781 Gene

Chromosome:
19
Start:
37,667,749 bp from pter
End:
37,692,322 bp from pter
Size:
24,574 bases
Orientation:
Minus strand

Genomic View for ZNF781 Gene

Genes around ZNF781 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF781 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF781 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF781 Gene

Proteins for ZNF781 Gene

  • Protein details for ZNF781 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8C0-ZN781_HUMAN
    Recommended name:
    Zinc finger protein 781
    Protein Accession:
    Q8N8C0
    Secondary Accessions:
    • Q2VPJ8

    Protein attributes for ZNF781 Gene

    Size:
    355 amino acids
    Molecular mass:
    41526 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF781 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF781 Gene

Post-translational modifications for ZNF781 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF781 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF781 Gene

Domains & Families for ZNF781 Gene

Gene Families for ZNF781 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF781 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF781 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N8C0

UniProtKB/Swiss-Prot:

ZN781_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF781: view

Function for ZNF781 Gene

Molecular function for ZNF781 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF781 Gene

Gene Ontology (GO) - Molecular Function for ZNF781 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF781: view
genes like me logo Genes that share phenotypes with ZNF781: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ZNF781
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF781 Gene

Localization for ZNF781 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF781 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF781 gene
Compartment Confidence
nucleus 5
mitochondrion 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF781 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF781: view

Pathways & Interactions for ZNF781 Gene

SuperPathways for ZNF781 Gene

No Data Available

Interacting Proteins for ZNF781 Gene

Gene Ontology (GO) - Biological Process for ZNF781 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF781: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF781 Gene

Drugs & Compounds for ZNF781 Gene

No Compound Related Data Available

Transcripts for ZNF781 Gene

Unigene Clusters for ZNF781 Gene

Zinc finger protein 781:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ZNF781
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF781 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7
SP1: -
SP2: - -
SP3: - -
SP4: -
SP5: - - - - -

Relevant External Links for ZNF781 Gene

GeneLoc Exon Structure for
ZNF781
ECgene alternative splicing isoforms for
ZNF781

Expression for ZNF781 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF781 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF781 Gene



NURSA nuclear receptor signaling pathways regulating expression of ZNF781 Gene:

ZNF781

SOURCE GeneReport for Unigene cluster for ZNF781 Gene:

Hs.722657

Evidence on tissue expression from TISSUES for ZNF781 Gene

  • Intestine(4.1)
  • Skin(4)
genes like me logo Genes that share expression patterns with ZNF781: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF781 Gene

Orthologs for ZNF781 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF781 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia ZNF781 34
  • 39 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm3055 34
  • 18 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia ZNF781 34
  • 15 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 24 (a)
OneToMany
-- 34
  • 22 (a)
OneToMany
-- 34
  • 13 (a)
OneToMany
Species where no ortholog for ZNF781 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF781 Gene

ENSEMBL:
Gene Tree for ZNF781 (if available)
TreeFam:
Gene Tree for ZNF781 (if available)

Paralogs for ZNF781 Gene

Pseudogenes.org Pseudogenes for ZNF781 Gene

genes like me logo Genes that share paralogs with ZNF781: view

No data available for Paralogs for ZNF781 Gene

Variants for ZNF781 Gene

Sequence variations from dbSNP and Humsavar for ZNF781 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000186256 -- 37,688,106(+) CCTTC(C/T)CTCCA intron-variant
rs1000555544 -- 37,674,575(+) GGCTG(A/T)GGCTG intron-variant
rs1000608016 -- 37,674,273(+) AAGAT(A/G)CTGTT intron-variant
rs1000754577 -- 37,693,043(+) TATTA(A/G)TACTT upstream-variant-2KB
rs1000791746 -- 37,689,696(+) CGGGC(A/G)AATTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF781 Gene

Variant ID Type Subtype PubMed ID
esv3644290 CNV loss 21293372
esv3644291 CNV loss 21293372
nsv579468 CNV gain 21841781

Variation tolerance for ZNF781 Gene

Residual Variation Intolerance Score: 50.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.86; 58.91% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF781 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF781

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF781 Gene

Disorders for ZNF781 Gene

Relevant External Links for ZNF781

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF781

No disorders were found for ZNF781 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF781 Gene

Publications for ZNF781 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 60
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 60
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for ZNF781 Gene

Sources for ZNF781 Gene

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