ZNF780B Gene
protein-coding GIFtS: 39
GCID: GC19M040534
|
|
zinc finger protein 780B(Previous name: zinc finger protein 779 )
(Previous symbol: ZNF779)
| |
Aliases
for ZNF780B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 780B1 2 | | Zinc Finger Protein 7791 2 3 | | ZNF7791 2 3 |
Export aliases for ZNF780B gene to outside databasesPrevious GC identifers: GC19M045232 GC19M036971 |
Summaries
for ZNF780B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: Z780B_HUMAN, Q9Y6R6Function: May be involved in transcriptional regulation (By similarity)
|
Genomic Views
for ZNF780B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF780B gene promoter:
SRF GR SREBP-1c SRF (504 AA) Pax-6 YY1 Ik-2 IRF-7A GR-alpha ZID
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF780B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF780B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.2 Ensembl cytogenetic band: 19q13.2 HGNC cytogenetic band: 19q13.2ZNF780B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M040534: view genomic region
(about GC identifiers)
Start:
|
40,534,167 bp from pter |
End:
|
40,562,116 bp from pter |
Size:
|
27,950 bases |
Orientation:
|
minus strand |
|
Proteins
for ZNF780B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: Z780B_HUMAN, Q9Y6R6 (See
protein sequence)Recommended Name: Zinc finger protein 780B Size: 833 amino acids; 96807 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: B9EH00Explore the universe of human proteins at neXtProt for ZNF780B: NX_Q9Y6R6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y6R6
ZNF780B Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_001005851.1
ENSEMBL proteins: ENSP00000391641 ENSP00000221355
Human Recombinant Protein Products for ZNF780B:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF780B for ontologies About GeneDecksing
ZNF780B Antibody Products:
Assay Products for ZNF780B: |
Protein
Domains /
Families
for ZNF780B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF780B for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y6R6ProtoNet protein and cluster: Q9Y6R6 2 Blocks protein families: IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: Z780B_HUMAN, Q9Y6R6Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 23 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF780B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: Z780B_HUMAN, Q9Y6R6Function: May be involved in transcriptional regulation (By similarity) Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF780B for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF780B (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF780B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF780B (NM_001005851) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF780B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF780B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF780B |
|
Pathways & Interactions
for ZNF780B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF780B
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF780B for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF780B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF780B
Search CenterWatch for drugs/clinical trials and news about ZNF780B / Z780B
|
Transcripts
for ZNF780B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF780B gene: NM_001005851.2 Unigene Cluster for ZNF780B: Zinc finger protein 780B Hs.101139 [show with all ESTs]Unigene Representative Sequence: NM_0010058512 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000434248(uc002omv.3 uc002omu.3) ENST00000221355
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF780B (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF780B
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF780B (NM_001005851) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF780B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF780B |
Additional cDNA sequence: AK122872.1 AK127063.1 BC136960.1 10 DOTS entries: DT.101982336 DT.92045878 DT.91757773 DT.91757774 DT.404627 DT.432456 DT.97833560 DT.121475698 DT.205513 DT.121475723 24/109 AceView cDNA sequences (see all 109): AW087725 BU675187 AI948743 AA534387 CB528635 AA628082 BX280743 BQ221795 BF195849 AI392839 AF315117 AW129204 CB240725 BQ010603 AL697955 BM782800 AI084622 CK903859 AK122872 BF061767 BQ011153 BX644568 AI891028 BQ424943
GeneLoc Exon Structure
|
Expression
for ZNF780B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF780B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTCTCCTAT
About this image
Genevestigator expression for ZNF780B
SOURCE GeneReport for Unigene cluster: Hs.101139
SABiosciences Custom PCR Arrays for ZNF780B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF780B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZNF780B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF780B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF780B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF780B |
Orthologs
for ZNF780B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF780B (if available)
TreeFam Gene Tree for ZNF780B (if available) |
Paralogs
for ZNF780B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF780B gene
- ZNF6162 ZNF1602 ZNF8502 ZNF992 ZNF5462 ZNF6652 ZNF7212 ZNF8362
- ZNF8412 ZNF912 ZNF432 ZNF1972 ZNF585A2 ZNF8082 ZNF7292 ZNF3472
- ZNF8452 ZNF1842 ZNF6582 ZNF585B2 ZNF6242 ZNF2082
18/493 SIMAP similar genes for ZNF780B using alignment to 4 protein entries: Z780B_HUMAN (see all proteins)
(see all similar genes):ZNF780A ZFS-4 ZNF78L1 kr-znf3 ZNF232 DKFZp313M0722
HZF36 ZFS-2 ZNF323 ZFS-1 ZNF146 DKFZp686M04222
ZNF502 smap-7 ZNF436 ZNF DKFZp686B16128 HZF41
ZNF780B for paralogs About GeneDecksing
|
Genomic Variants
for ZNF780B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF780B (40534167 - 40562116 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF780B: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF780B |
|
Disorders
/ Diseases
for ZNF780B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF780B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF780B gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF780B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF780B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF780B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF780B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF780B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF780B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF780B gene:
Search GeneIP for patents involving ZNF780B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF780B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF780B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF780B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF780B | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF780B | | OriGene 3'-UTR Clone for ZNF780B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF780B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF780B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF780B | | OriGene Custom Protein Services for ZNF780B | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF780B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF780B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF780B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF780B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF780B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF780B |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ZNF780B |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ZNF780B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF780B |
|  |  |  |  | | | | Search ThermoFisher Antibodies for ZNF780B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF780B |
| |  | |
|
|
|
