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Aliases for ZNF780B Gene

Aliases for ZNF780B Gene

  • Zinc Finger Protein 780B 2 3
  • Zinc Finger Protein 779 2 3 4
  • ZNF779 3 4

External Ids for ZNF780B Gene

Previous HGNC Symbols for ZNF780B Gene

  • ZNF779

Previous GeneCards Identifiers for ZNF780B Gene

  • GC19M045232
  • GC19M040534
  • GC19M036971

Summaries for ZNF780B Gene

GeneCards Summary for ZNF780B Gene

ZNF780B (Zinc Finger Protein 780B) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF268.

UniProtKB/Swiss-Prot for ZNF780B Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF780B Gene

Genomics for ZNF780B Gene

Regulatory Elements for ZNF780B Gene

Genomic Location for ZNF780B Gene

Chromosome:
19
Start:
40,028,260 bp from pter
End:
40,059,027 bp from pter
Size:
30,768 bases
Orientation:
Minus strand

Genomic View for ZNF780B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF780B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF780B Gene

Proteins for ZNF780B Gene

  • Protein details for ZNF780B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y6R6-Z780B_HUMAN
    Recommended name:
    Zinc finger protein 780B
    Protein Accession:
    Q9Y6R6
    Secondary Accessions:
    • B9EH00

    Protein attributes for ZNF780B Gene

    Size:
    833 amino acids
    Molecular mass:
    96807 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF780B Gene

Proteomics data for ZNF780B Gene at MOPED

Post-translational modifications for ZNF780B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF780B Gene

No data available for DME Specific Peptides for ZNF780B Gene

Domains & Families for ZNF780B Gene

Gene Families for ZNF780B Gene

Protein Domains for ZNF780B Gene

Suggested Antigen Peptide Sequences for ZNF780B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9Y6R6

UniProtKB/Swiss-Prot:

Z780B_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 23 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 23 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF780B: view

Function for ZNF780B Gene

Molecular function for ZNF780B Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF780B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF780B: view

Phenotypes for ZNF780B Gene

GenomeRNAi human phenotypes for ZNF780B:
genes like me logo Genes that share phenotypes with ZNF780B: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF780B Gene

Localization for ZNF780B Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF780B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF780B Gene COMPARTMENTS Subcellular localization image for ZNF780B gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF780B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF780B: view

Pathways & Interactions for ZNF780B Gene

SuperPathways for ZNF780B Gene

No Data Available

Interacting Proteins for ZNF780B Gene

Gene Ontology (GO) - Biological Process for ZNF780B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF780B: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF780B Gene

Drugs & Compounds for ZNF780B Gene

No Compound Related Data Available

Transcripts for ZNF780B Gene

Unigene Clusters for ZNF780B Gene

Zinc finger protein 780B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF780B Gene

No ASD Table

Relevant External Links for ZNF780B Gene

GeneLoc Exon Structure for
ZNF780B
ECgene alternative splicing isoforms for
ZNF780B

Expression for ZNF780B Gene

mRNA expression in normal human tissues for ZNF780B Gene

SOURCE GeneReport for Unigene cluster for ZNF780B Gene Hs.101139

genes like me logo Genes that share expression patterns with ZNF780B: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF780B Gene

Orthologs for ZNF780B Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF780B Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia LOC100684414 35
  • 78.22 (n)
  • 69.59 (a)
ZNF780B 36
  • 53 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp780b 35
  • 70.58 (n)
  • 59.52 (a)
Zfp780b 16
1700049G17Rik 36
  • 53 (a)
OneToMany
Zfp780b 36
  • 57 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Zfp780b 35
  • 68.55 (n)
  • 55.9 (a)
cow
(Bos Taurus)
Mammalia -- 36
  • 41 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
-- 36
  • 33 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 43 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 51 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 51 (a)
ManyToMany
Species with no ortholog for ZNF780B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF780B Gene

ENSEMBL:
Gene Tree for ZNF780B (if available)
TreeFam:
Gene Tree for ZNF780B (if available)

Paralogs for ZNF780B Gene

(516) SIMAP similar genes for ZNF780B Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF780B: view

Variants for ZNF780B Gene

Sequence variations from dbSNP and Humsavar for ZNF780B Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs13775 -- 40,037,377(+) cacta(A/G)gtctg intron-variant
rs186800 -- 40,041,625(+) ttagc(G/T)cttct intron-variant
rs416283 -- 40,045,049(-) ATAAA(C/T)GTAGC intron-variant
rs420413 -- 40,044,559(-) tctgg(A/G)aaaga intron-variant
rs420579 -- 40,058,623(-) ctaac(A/G)tatta utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF780B Gene

Variant ID Type Subtype PubMed ID
nsv2486 CNV Insertion 18451855

Variation tolerance for ZNF780B Gene

Residual Variation Intolerance Score: 72.57% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.48; 64.36% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF780B Gene

HapMap Linkage Disequilibrium report
ZNF780B
Human Gene Mutation Database (HGMD)
ZNF780B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF780B Gene

Disorders for ZNF780B Gene

Relevant External Links for ZNF780B

Genetic Association Database (GAD)
ZNF780B
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF780B
genes like me logo Genes that share disorders with ZNF780B: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF780B Gene

Publications for ZNF780B Gene

  1. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PMID: 17903293) Benjamin E.J. … Vasan R.S. (BMC Med. Genet. 2007) 67
  2. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PMID: 17903299) Kathiresan S. … Cupples L.A. (BMC Med. Genet. 2007) 67
  3. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PMID: 17903301) Vasan R.S. … Benjamin E.J. (BMC Med. Genet. 2007) 67
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for ZNF780B Gene

Sources for ZNF780B Gene

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