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Aliases for ZNF780A Gene

Aliases for ZNF780A Gene

  • Zinc Finger Protein 780A 2 3 5
  • ZNF780 3

External Ids for ZNF780A Gene

Previous GeneCards Identifiers for ZNF780A Gene

  • GC19M045268
  • GC19M040575
  • GC19M037011

Summaries for ZNF780A Gene

GeneCards Summary for ZNF780A Gene

ZNF780A (Zinc Finger Protein 780A) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF607.

UniProtKB/Swiss-Prot for ZNF780A Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF780A Gene

Genomics for ZNF780A Gene

Regulatory Elements for ZNF780A Gene

Promoters for ZNF780A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF780A on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF780A Gene

Chromosome:
19
Start:
40,069,152 bp from pter
End:
40,091,736 bp from pter
Size:
22,585 bases
Orientation:
Minus strand

Genomic View for ZNF780A Gene

Genes around ZNF780A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF780A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF780A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF780A Gene

Proteins for ZNF780A Gene

  • Protein details for ZNF780A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O75290-Z780A_HUMAN
    Recommended name:
    Zinc finger protein 780A
    Protein Accession:
    O75290
    Secondary Accessions:
    • E9PB48
    • Q6ZN87

    Protein attributes for ZNF780A Gene

    Size:
    641 amino acids
    Molecular mass:
    74531 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC34327.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF780A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF780A Gene

Proteomics data for ZNF780A Gene at MOPED

Post-translational modifications for ZNF780A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF780A Gene

Domains & Families for ZNF780A Gene

Gene Families for ZNF780A Gene

Protein Domains for ZNF780A Gene

Suggested Antigen Peptide Sequences for ZNF780A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O75290

UniProtKB/Swiss-Prot:

Z780A_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 17 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 17 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF780A: view

Function for ZNF780A Gene

Molecular function for ZNF780A Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF780A Gene

GenomeRNAi human phenotypes for ZNF780A:
genes like me logo Genes that share phenotypes with ZNF780A: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF780A Gene

Localization for ZNF780A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF780A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF780A Gene COMPARTMENTS Subcellular localization image for ZNF780A gene
Compartment Confidence
nucleus 5
cytosol 3

No data available for Gene Ontology (GO) - Cellular Components for ZNF780A Gene

Pathways & Interactions for ZNF780A Gene

SuperPathways for ZNF780A Gene

No Data Available

Interacting Proteins for ZNF780A Gene

Gene Ontology (GO) - Biological Process for ZNF780A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZNF780A Gene

Drugs & Compounds for ZNF780A Gene

No Compound Related Data Available

Transcripts for ZNF780A Gene

Unigene Clusters for ZNF780A Gene

Zinc finger protein 780A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF780A Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b
SP1: -
SP2: -
SP3: -
SP4: - - -

Relevant External Links for ZNF780A Gene

GeneLoc Exon Structure for
ZNF780A
ECgene alternative splicing isoforms for
ZNF780A

Expression for ZNF780A Gene

mRNA expression in normal human tissues for ZNF780A Gene

Protein differential expression in normal tissues from HIPED for ZNF780A Gene

This gene is overexpressed in Lung (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF780A Gene



SOURCE GeneReport for Unigene cluster for ZNF780A Gene Hs.115140

genes like me logo Genes that share expression patterns with ZNF780A: view

Protein tissue co-expression partners for ZNF780A Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF780A Gene

Orthologs for ZNF780A Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF780A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF780A 36
  • 70 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF383 36
  • 49 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp607 35
  • 69.43 (n)
  • 57.43 (a)
Zfp607 16
C030039L03Rik 36
  • 55 (a)
OneToMany
Zfp59 36
  • 51 (a)
OneToMany
Zfp60 36
  • 49 (a)
OneToMany
Zfp607 36
  • 53 (a)
OneToMany
Zfp850 36
  • 49 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 47 (a)
OneToMany
Species with no ortholog for ZNF780A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF780A Gene

ENSEMBL:
Gene Tree for ZNF780A (if available)
TreeFam:
Gene Tree for ZNF780A (if available)

Paralogs for ZNF780A Gene

(525) SIMAP similar genes for ZNF780A Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF780A: view

Variants for ZNF780A Gene

Sequence variations from dbSNP and Humsavar for ZNF780A Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs399405 -- 40,074,519(-) GCATC(C/T)TGAAT intron-variant, reference, synonymous-codon
rs337780 -- 40,070,822(+) TCTCT(C/T)TTTTA utr-variant-3-prime
rs337781 -- 40,071,457(+) TTGTA(C/T)TGAAT utr-variant-3-prime
rs337782 -- 40,072,103(+) aactc(A/G)ttctt utr-variant-3-prime
rs337783 -- 40,072,346(+) ctagc(A/T)ggatt downstream-variant-500B, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF780A Gene

Variant ID Type Subtype PubMed ID
nsv2488 CNV Loss 18451855

Variation tolerance for ZNF780A Gene

Residual Variation Intolerance Score: 67.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.23; 52.46% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF780A Gene

HapMap Linkage Disequilibrium report
ZNF780A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF780A Gene

Disorders for ZNF780A Gene

Relevant External Links for ZNF780A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF780A

No disorders were found for ZNF780A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF780A Gene

Publications for ZNF780A Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4 67
  2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF780A Gene

Sources for ZNF780A Gene

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