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Aliases for ZNF777 Gene

Aliases for ZNF777 Gene

  • Zinc Finger Protein 777 2 3 5
  • KIAA1285 4

External Ids for ZNF777 Gene

Previous GeneCards Identifiers for ZNF777 Gene

  • GC07M148759
  • GC07M149128
  • GC07M143204

Summaries for ZNF777 Gene

GeneCards Summary for ZNF777 Gene

ZNF777 (Zinc Finger Protein 777) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF746.

UniProtKB/Swiss-Prot for ZNF777 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF777 Gene

Genomics for ZNF777 Gene

Regulatory Elements for ZNF777 Gene

Enhancers for ZNF777 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF777 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF777 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF777 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF777 Gene

149,431,363 bp from pter
149,461,123 bp from pter
29,761 bases
Minus strand

Genomic View for ZNF777 Gene

Genes around ZNF777 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF777 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF777 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF777 Gene

Proteins for ZNF777 Gene

  • Protein details for ZNF777 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 777
    Protein Accession:
    Secondary Accessions:
    • Q8N2R2
    • Q8N659

    Protein attributes for ZNF777 Gene

    760 amino acids
    Molecular mass:
    85176 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH23985.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA86599.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAC11033.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF777 Gene


neXtProt entry for ZNF777 Gene

Proteomics data for ZNF777 Gene at MOPED

Post-translational modifications for ZNF777 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF777 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF777 Gene

Domains & Families for ZNF777 Gene

Gene Families for ZNF777 Gene

Protein Domains for ZNF777 Gene

Suggested Antigen Peptide Sequences for ZNF777 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 6 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 6 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF777: view

Function for ZNF777 Gene

Molecular function for ZNF777 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF777 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
genes like me logo Genes that share ontologies with ZNF777: view
genes like me logo Genes that share phenotypes with ZNF777: view

Animal Model Products

CRISPR Products

miRNA for ZNF777 Gene

miRTarBase miRNAs that target ZNF777

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF777 Gene

Localization for ZNF777 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF777 Gene

Subcellular locations from

Jensen Localization Image for ZNF777 Gene COMPARTMENTS Subcellular localization image for ZNF777 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF777 Gene

Pathways & Interactions for ZNF777 Gene

SuperPathways for ZNF777 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF777: view

Pathways by source for ZNF777 Gene

2 Reactome pathways for ZNF777 Gene

Interacting Proteins for ZNF777 Gene

Gene Ontology (GO) - Biological Process for ZNF777 Gene


No data available for SIGNOR curated interactions for ZNF777 Gene

Drugs & Compounds for ZNF777 Gene

No Compound Related Data Available

Transcripts for ZNF777 Gene

mRNA/cDNA for ZNF777 Gene

Unigene Clusters for ZNF777 Gene

Zinc finger protein 777:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF777 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b
SP1: -

Relevant External Links for ZNF777 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF777 Gene

mRNA expression in normal human tissues for ZNF777 Gene

Protein differential expression in normal tissues from HIPED for ZNF777 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF777 Gene

SOURCE GeneReport for Unigene cluster for ZNF777 Gene Hs.38512

genes like me logo Genes that share expression patterns with ZNF777: view

Protein tissue co-expression partners for ZNF777 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF777 Gene

Orthologs for ZNF777 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF777 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF777 35
  • 89.29 (n)
  • 91.94 (a)
ZNF777 36
  • 93 (a)
(Canis familiaris)
Mammalia ZNF777 35
  • 90.18 (n)
  • 93.84 (a)
ZNF777 36
  • 94 (a)
(Mus musculus)
Mammalia Zfp777 35
  • 86.53 (n)
  • 91.56 (a)
Zfp777 16
Zfp777 36
  • 86 (a)
(Pan troglodytes)
Mammalia ZNF777 35
  • 99.68 (n)
  • 99.88 (a)
ZNF777 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Zfp777 35
  • 86.57 (n)
  • 91.07 (a)
(Monodelphis domestica)
Mammalia ZNF777 36
  • 78 (a)
(Ornithorhynchus anatinus)
Mammalia ZNF777 36
  • 54 (a)
(Gallus gallus)
Aves LOC101750773 35
  • 80.48 (n)
  • 76.1 (a)
ZNF777 36
  • 56 (a)
(Anolis carolinensis)
Reptilia ZNF777 36
  • 60 (a)
Species with no ortholog for ZNF777:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF777 Gene

Gene Tree for ZNF777 (if available)
Gene Tree for ZNF777 (if available)

Paralogs for ZNF777 Gene

Paralogs for ZNF777 Gene Pseudogenes for ZNF777 Gene

genes like me logo Genes that share paralogs with ZNF777: view

Variants for ZNF777 Gene

Sequence variations from dbSNP and Humsavar for ZNF777 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs3735318 - 149,455,815(-) CTGGC(C/T)GGATG reference, missense
rs3735319 - 149,455,679(-) AGAAG(C/T)CTCCC reference, missense
rs17852167 - 149,432,738(+) CACTG(A/C/G/T)GGGGT reference, missense
rs882794 -- 149,445,638(-) cagat(A/G)ttgag intron-variant
rs940772 -- 149,456,974(-) ACCTG(C/T)TGCAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF777 Gene

Variant ID Type Subtype PubMed ID
esv28225 CNV Loss 19812545

Variation tolerance for ZNF777 Gene

Residual Variation Intolerance Score: 14.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.14; 61.42% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF777 Gene

Disorders for ZNF777 Gene

Relevant External Links for ZNF777

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF777 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF777 Gene

Publications for ZNF777 Gene

  1. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10574462) Nagase T. … Ohara O. (DNA Res. 1999) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF777 Gene

Sources for ZNF777 Gene