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Aliases for ZNF776 Gene

Aliases for ZNF776 Gene

  • Zinc Finger Protein 776 2 3

External Ids for ZNF776 Gene

Previous GeneCards Identifiers for ZNF776 Gene

  • GC19P062950
  • GC19P058258
  • GC19P054570

Summaries for ZNF776 Gene

GeneCards Summary for ZNF776 Gene

ZNF776 (Zinc Finger Protein 776) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF17.

UniProtKB/Swiss-Prot for ZNF776 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF776 Gene

Genomics for ZNF776 Gene

Regulatory Elements for ZNF776 Gene

Transcription factor binding sites by QIAGEN in the ZNF776 gene promoter:

Genomic Location for ZNF776 Gene

Start:
57,746,796 bp from pter
End:
57,758,159 bp from pter
Size:
11,364 bases
Orientation:
Plus strand

Genomic View for ZNF776 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF776 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF776 Gene

Proteins for ZNF776 Gene

  • Protein details for ZNF776 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q68DI1-ZN776_HUMAN
    Recommended name:
    Zinc finger protein 776
    Protein Accession:
    Q68DI1
    Secondary Accessions:
    • Q6ZS36
    • Q8N968

    Protein attributes for ZNF776 Gene

    Size:
    518 amino acids
    Molecular mass:
    59613 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC04588.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305}; Sequence=BAC87119.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for ZNF776 Gene

Proteomics data for ZNF776 Gene at MOPED

Post-translational modifications for ZNF776 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF776 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF776 Gene

Domains for ZNF776 Gene

Gene Families for ZNF776 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF776 Gene

Graphical View of Domain Structure for InterPro Entry

Q68DI1

UniProtKB/Swiss-Prot:

ZN776_HUMAN :
  • Q68DI1
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 11 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF776: view

Function for ZNF776 Gene

Molecular function for ZNF776 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF776 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF776: view

miRNA for ZNF776 Gene

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF776 Gene

Localization for ZNF776 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF776 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF776 Gene COMPARTMENTS Subcellular localization image for ZNF776 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF776 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF776: view

Pathways for ZNF776 Gene

SuperPathways for ZNF776 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF776: view

Pathways by source for ZNF776 Gene

2 Reactome pathways for ZNF776 Gene

Interacting Proteins for ZNF776 Gene

Gene Ontology (GO) - Biological Process for ZNF776 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF776: view

Transcripts for ZNF776 Gene

Unigene Clusters for ZNF776 Gene

Zinc finger protein 776:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF776 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c
SP1: - -
SP2:
SP3:
SP4: - - -
SP5: -
SP6:

Relevant External Links for ZNF776 Gene

GeneLoc Exon Structure for
ZNF776
ECgene alternative splicing isoforms for
ZNF776

Expression for ZNF776 Gene

mRNA expression in normal human tissues for ZNF776 Gene

SOURCE GeneReport for Unigene cluster for ZNF776 Gene Hs.720254

genes like me logo Genes that share expressions with ZNF776: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF776 Gene

Orthologs for ZNF776 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF776 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF776 35
  • 99.42 (n)
  • 98.84 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 49 (a)
OneToMany
Species with no ortholog for ZNF776:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF776 Gene

ENSEMBL:
Gene Tree for ZNF776 (if available)
TreeFam:
Gene Tree for ZNF776 (if available)

Paralogs for ZNF776 Gene

Selected SIMAP similar genes for ZNF776 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF776: view

Variants for ZNF776 Gene

Sequence variations from dbSNP and Humsavar for ZNF776 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1462 -- 57,757,953(-) ATAAA(C/G)AAAAA utr-variant-3-prime
rs13037 -- 57,757,805(+) TCCAT(C/G)CTCCA utr-variant-3-prime
rs1063854 -- 57,757,058(+) GTTCA(A/G)CTCCT utr-variant-3-prime
rs2009609 -- 57,752,631(-) CTCGT(C/T)ATGTT intron-variant
rs2074080 -- 57,746,752(+) ATGAG(A/G)GCTCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF776 Gene

Variant ID Type Subtype PubMed ID
nsv912528 CNV Gain 21882294
nsv912529 CNV Loss 21882294

Relevant External Links for ZNF776 Gene

HapMap Linkage Disequilibrium report
ZNF776

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF776 Gene

Disorders for ZNF776 Gene

Relevant External Links for ZNF776

Genetic Association Database (GAD)
ZNF776
Human Genome Epidemiology (HuGE) Navigator
ZNF776
genes like me logo Genes that share disorders with ZNF776: view

No data available for UniProtKB/Swiss-Prot for ZNF776 Gene

Publications for ZNF776 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4
  4. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4
  5. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 3

Products for ZNF776 Gene

Sources for ZNF776 Gene

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