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Aliases for ZNF776 Gene

Aliases for ZNF776 Gene

  • Zinc Finger Protein 776 2 3 5

External Ids for ZNF776 Gene

Previous GeneCards Identifiers for ZNF776 Gene

  • GC19P062950
  • GC19P058258
  • GC19P054570

Summaries for ZNF776 Gene

GeneCards Summary for ZNF776 Gene

ZNF776 (Zinc Finger Protein 776) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF17.

UniProtKB/Swiss-Prot for ZNF776 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF776 Gene

Genomics for ZNF776 Gene

Regulatory Elements for ZNF776 Gene

Promoters for ZNF776 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF776 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the ZNF776 gene promoter:

Genomic Location for ZNF776 Gene

Chromosome:
19
Start:
57,746,796 bp from pter
End:
57,758,159 bp from pter
Size:
11,364 bases
Orientation:
Plus strand

Genomic View for ZNF776 Gene

Genes around ZNF776 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF776 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF776 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF776 Gene

Proteins for ZNF776 Gene

  • Protein details for ZNF776 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q68DI1-ZN776_HUMAN
    Recommended name:
    Zinc finger protein 776
    Protein Accession:
    Q68DI1
    Secondary Accessions:
    • Q6ZS36
    • Q8N968

    Protein attributes for ZNF776 Gene

    Size:
    518 amino acids
    Molecular mass:
    59613 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC04588.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305}; Sequence=BAC87119.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for ZNF776 Gene

Proteomics data for ZNF776 Gene at MOPED

Post-translational modifications for ZNF776 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF776 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF776 Gene

Domains & Families for ZNF776 Gene

Gene Families for ZNF776 Gene

Protein Domains for ZNF776 Gene

Suggested Antigen Peptide Sequences for ZNF776 Gene

Graphical View of Domain Structure for InterPro Entry

Q68DI1

UniProtKB/Swiss-Prot:

ZN776_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 11 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 11 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF776: view

Function for ZNF776 Gene

Molecular function for ZNF776 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF776 Gene

GenomeRNAi human phenotypes for ZNF776:
genes like me logo Genes that share phenotypes with ZNF776: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF776 Gene

Localization for ZNF776 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF776 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF776 Gene COMPARTMENTS Subcellular localization image for ZNF776 gene
Compartment Confidence
nucleus 5
cytosol 3

No data available for Gene Ontology (GO) - Cellular Components for ZNF776 Gene

Pathways & Interactions for ZNF776 Gene

SuperPathways for ZNF776 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF776: view

Pathways by source for ZNF776 Gene

2 Reactome pathways for ZNF776 Gene

Interacting Proteins for ZNF776 Gene

Gene Ontology (GO) - Biological Process for ZNF776 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF776: view

No data available for SIGNOR curated interactions for ZNF776 Gene

Drugs & Compounds for ZNF776 Gene

No Compound Related Data Available

Transcripts for ZNF776 Gene

Unigene Clusters for ZNF776 Gene

Zinc finger protein 776:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF776 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c
SP1: - -
SP2:
SP3:
SP4: - - -
SP5: -
SP6:

Relevant External Links for ZNF776 Gene

GeneLoc Exon Structure for
ZNF776
ECgene alternative splicing isoforms for
ZNF776

Expression for ZNF776 Gene

mRNA expression in normal human tissues for ZNF776 Gene

SOURCE GeneReport for Unigene cluster for ZNF776 Gene Hs.720254

genes like me logo Genes that share expression patterns with ZNF776: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF776 Gene

Orthologs for ZNF776 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF776 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF776 35
  • 99.42 (n)
  • 98.84 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 49 (a)
OneToMany
Species with no ortholog for ZNF776:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF776 Gene

ENSEMBL:
Gene Tree for ZNF776 (if available)
TreeFam:
Gene Tree for ZNF776 (if available)

Paralogs for ZNF776 Gene

(519) SIMAP similar genes for ZNF776 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF776: view

Variants for ZNF776 Gene

Sequence variations from dbSNP and Humsavar for ZNF776 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1462 -- 57,757,953(-) ATAAA(C/G)AAAAA utr-variant-3-prime
rs13037 -- 57,757,805(+) TCCAT(C/G)CTCCA utr-variant-3-prime
rs2074080 -- 57,746,752(+) ATGAG(A/G)GCTCA upstream-variant-2KB
rs2074081 -- 57,747,221(+) TCTAT(A/G)GGCCC intron-variant
rs9676883 -- 57,745,708(+) AAAAA(A/G)AATAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF776 Gene

Variant ID Type Subtype PubMed ID
nsv912528 CNV Gain 21882294
nsv912529 CNV Loss 21882294

Variation tolerance for ZNF776 Gene

Residual Variation Intolerance Score: 20.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.49; 10.67% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF776 Gene

HapMap Linkage Disequilibrium report
ZNF776

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF776 Gene

Disorders for ZNF776 Gene

Relevant External Links for ZNF776

Genetic Association Database (GAD)
ZNF776
Human Genome Epidemiology (HuGE) Navigator
ZNF776
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF776

No disorders were found for ZNF776 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF776 Gene

Publications for ZNF776 Gene

  1. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48 67
  2. Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis. (PMID: 25085501) Bunyavanich S. … Weiss S.T. (BMC Med Genomics 2014) 3
  3. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF776 Gene

Sources for ZNF776 Gene

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