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Aliases for ZNF773 Gene

Aliases for ZNF773 Gene

  • Zinc Finger Protein 773 2 3
  • Zinc Finger Protein 419B 2 3 4
  • ZNF419B 3 4

External Ids for ZNF773 Gene

Previous Symbols for ZNF773 Gene

  • ZNF419B

Summaries for ZNF773 Gene

GeneCards Summary for ZNF773 Gene

ZNF773 (Zinc Finger Protein 773) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF17.

UniProtKB/Swiss-Prot for ZNF773 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF773 Gene

Genomics for ZNF773 Gene

Genomic Location for ZNF773 Gene

Start:
57,499,854 bp from pter
End:
57,518,404 bp from pter
Size:
18,551 bases
Orientation:
Plus strand

Genomic View for ZNF773 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF773 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF773 Gene

Regulatory Elements for ZNF773 Gene

Proteins for ZNF773 Gene

  • Protein details for ZNF773 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PK81-ZN773_HUMAN
    Recommended name:
    Zinc finger protein 773
    Protein Accession:
    Q6PK81
    Secondary Accessions:
    • Q96DL8

    Protein attributes for ZNF773 Gene

    Size:
    442 amino acids
    Molecular mass:
    50502 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF773 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF773 Gene

Proteomics data for ZNF773 Gene at MOPED

Post-translational modifications for ZNF773 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys203, Lys217, Lys320, and Lys343

Other Protein References for ZNF773 Gene

No data available for DME Specific Peptides for ZNF773 Gene

Domains for ZNF773 Gene

Gene Families for ZNF773 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF773 Gene

UniProtKB/Swiss-Prot:

ZN773_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q6PK81
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q6PK81
Similarity:
  • Contains 9 C2H2-type zinc fingers.:
    • Q6PK81
genes like me logo Genes that share domains with ZNF773: view

Function for ZNF773 Gene

Molecular function for ZNF773 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF773 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF773: view

Phenotypes for ZNF773 Gene

GenomeRNAi human phenotypes for ZNF773:
genes like me logo Genes that share phenotypes with ZNF773: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF773 Gene

Localization for ZNF773 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF773 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF773 Gene COMPARTMENTS Subcellular localization image for ZNF773 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF773 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF773: view

Pathways for ZNF773 Gene

SuperPathways for ZNF773 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF773: view

Pathways by source for ZNF773 Gene

2 Reactome pathways for ZNF773 Gene

Gene Ontology (GO) - Biological Process for ZNF773 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF773: view

Transcripts for ZNF773 Gene

Unigene Clusters for ZNF773 Gene

Zinc finger protein 773:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF773 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5
SP1:
SP2:
SP3: - -

Relevant External Links for ZNF773 Gene

GeneLoc Exon Structure for
ZNF773
ECgene alternative splicing isoforms for
ZNF773

Expression for ZNF773 Gene

mRNA expression in normal human tissues for ZNF773 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF773 Gene

SOURCE GeneReport for Unigene cluster for ZNF773 Gene Hs.579576

genes like me logo Genes that share expressions with ZNF773: view

Orthologs for ZNF773 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF773 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF773 36
  • 98.79 (n)
  • 97.96 (a)
ZNF773 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 71 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp534 37
  • 30 (a)
ManyToMany
Zfp772 36
  • 65.07 (n)
  • 52.13 (a)
Zfp773 16
rat
(Rattus norvegicus)
Mammalia Zfp978 36
  • 66.54 (n)
  • 51.84 (a)
Species with no ortholog for ZNF773:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF773 Gene

ENSEMBL:
Gene Tree for ZNF773 (if available)
TreeFam:
Gene Tree for ZNF773 (if available)

Paralogs for ZNF773 Gene

Selected SIMAP similar genes for ZNF773 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for ZNF773 Gene

genes like me logo Genes that share paralogs with ZNF773: view

Variants for ZNF773 Gene

Sequence variations from dbSNP and Humsavar for ZNF773 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs739585 -- 57,499,002(-) CCCAT(G/T)CTCAT upstream-variant-2KB
rs739586 -- 57,500,142(-) GATTC(A/G)GGGGA intron-variant
rs756980 -- 57,506,267(+) CACAC(A/G)CTAAT intron-variant
rs916772 -- 57,509,328(+) GATAA(A/G)GAATT intron-variant
rs975804 -- 57,511,135(+) gtgtc(C/T)gcccc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF773 Gene

Variant ID Type Subtype PubMed ID
nsv912525 CNV Loss 21882294
esv2719071 CNV Deletion 23290073
nsv522762 CNV Loss 19592680
nsv525323 CNV Loss 19592680
esv2719072 CNV Deletion 23290073
esv2719074 CNV Deletion 23290073

Relevant External Links for ZNF773 Gene

HapMap Linkage Disequilibrium report
ZNF773

Disorders for ZNF773 Gene

No disorders were found for ZNF773 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF773 Gene

Publications for ZNF773 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  4. Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. (PMID: 20562864) Nozawa R.S. … Obuse C. (Nat. Cell Biol. 2010) 3
  5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3

Products for ZNF773 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF773
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF773
    • Block miRNA regulation of ZNF773 using miScript Target Protectors

    Sources for ZNF773 Gene

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