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Aliases for ZNF773 Gene

Aliases for ZNF773 Gene

  • Zinc Finger Protein 773 2 3 5
  • Zinc Finger Protein 419B 2 3 4
  • ZNF419B 3 4

External Ids for ZNF773 Gene

Previous HGNC Symbols for ZNF773 Gene

  • ZNF419B

Previous GeneCards Identifiers for ZNF773 Gene

  • GC19P062706
  • GC19P058011
  • GC19P054323

Summaries for ZNF773 Gene

GeneCards Summary for ZNF773 Gene

ZNF773 (Zinc Finger Protein 773) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF17.

UniProtKB/Swiss-Prot for ZNF773 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF773 Gene

Genomics for ZNF773 Gene

Regulatory Elements for ZNF773 Gene

Promoters for ZNF773 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF773 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF773 Gene

Chromosome:
19
Start:
57,499,854 bp from pter
End:
57,518,437 bp from pter
Size:
18,584 bases
Orientation:
Plus strand

Genomic View for ZNF773 Gene

Genes around ZNF773 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF773 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF773 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF773 Gene

Proteins for ZNF773 Gene

  • Protein details for ZNF773 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PK81-ZN773_HUMAN
    Recommended name:
    Zinc finger protein 773
    Protein Accession:
    Q6PK81
    Secondary Accessions:
    • Q96DL8

    Protein attributes for ZNF773 Gene

    Size:
    442 amino acids
    Molecular mass:
    50502 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF773 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF773 Gene

Proteomics data for ZNF773 Gene at MOPED

Post-translational modifications for ZNF773 Gene

  • Ubiquitination at Lys 343
  • Modification sites at PhosphoSitePlus

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for ZNF773

No data available for DME Specific Peptides for ZNF773 Gene

Domains & Families for ZNF773 Gene

Gene Families for ZNF773 Gene

Protein Domains for ZNF773 Gene

Suggested Antigen Peptide Sequences for ZNF773 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6PK81

UniProtKB/Swiss-Prot:

ZN773_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF773: view

Function for ZNF773 Gene

Molecular function for ZNF773 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF773 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
genes like me logo Genes that share ontologies with ZNF773: view
genes like me logo Genes that share phenotypes with ZNF773: view

Animal Model Products

CRISPR Products

miRNA for ZNF773 Gene

miRTarBase miRNAs that target ZNF773

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF773 Gene

Localization for ZNF773 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF773 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF773 Gene COMPARTMENTS Subcellular localization image for ZNF773 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF773 Gene

Pathways & Interactions for ZNF773 Gene

SuperPathways for ZNF773 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF773: view

Pathways by source for ZNF773 Gene

2 Reactome pathways for ZNF773 Gene

Gene Ontology (GO) - Biological Process for ZNF773 Gene

None

No data available for SIGNOR curated interactions for ZNF773 Gene

Drugs & Compounds for ZNF773 Gene

No Compound Related Data Available

Transcripts for ZNF773 Gene

Unigene Clusters for ZNF773 Gene

Zinc finger protein 773:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF773 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5
SP1:
SP2:
SP3: - -

Relevant External Links for ZNF773 Gene

GeneLoc Exon Structure for
ZNF773
ECgene alternative splicing isoforms for
ZNF773

Expression for ZNF773 Gene

mRNA expression in normal human tissues for ZNF773 Gene

Protein differential expression in normal tissues from HIPED for ZNF773 Gene

This gene is overexpressed in Fetal heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF773 Gene



SOURCE GeneReport for Unigene cluster for ZNF773 Gene Hs.579576

genes like me logo Genes that share expression patterns with ZNF773: view

Protein tissue co-expression partners for ZNF773 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF773 Gene

Orthologs for ZNF773 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF773 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Zfp772 35
  • 65.07 (n)
  • 52.13 (a)
Zfp772 16
Zfp534 36
  • 30 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia ZNF773 35
  • 98.79 (n)
  • 97.96 (a)
ZNF773 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp978 35
  • 66.54 (n)
  • 51.84 (a)
cow
(Bos Taurus)
Mammalia -- 36
  • 71 (a)
OneToMany
Species with no ortholog for ZNF773:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF773 Gene

ENSEMBL:
Gene Tree for ZNF773 (if available)
TreeFam:
Gene Tree for ZNF773 (if available)

Paralogs for ZNF773 Gene

(501) SIMAP similar genes for ZNF773 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for ZNF773 Gene

genes like me logo Genes that share paralogs with ZNF773: view

Variants for ZNF773 Gene

Sequence variations from dbSNP and Humsavar for ZNF773 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs739585 -- 57,499,002(-) CCCAT(G/T)CTCAT upstream-variant-2KB
rs739586 -- 57,500,142(-) GATTC(A/G)GGGGA intron-variant
rs756980 -- 57,506,267(+) CACAC(A/G/T)CTAAT intron-variant
rs2005684 -- 57,505,994(+) ATGAG(C/G)CACCG intron-variant
rs916772 -- 57,509,328(+) GATAA(A/G)GAATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF773 Gene

Variant ID Type Subtype PubMed ID
nsv912525 CNV Loss 21882294
esv2719071 CNV Deletion 23290073
nsv522762 CNV Loss 19592680
nsv525323 CNV Loss 19592680
esv2719072 CNV Deletion 23290073
esv2719074 CNV Deletion 23290073

Variation tolerance for ZNF773 Gene

Residual Variation Intolerance Score: 89.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.78; 66.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF773 Gene

HapMap Linkage Disequilibrium report
ZNF773

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF773 Gene

Disorders for ZNF773 Gene

Relevant External Links for ZNF773

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF773

No disorders were found for ZNF773 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF773 Gene

Publications for ZNF773 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. (PMID: 20562864) Nozawa R.S. … Obuse C. (Nat. Cell Biol. 2010) 3
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for ZNF773 Gene

Sources for ZNF773 Gene

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