Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF772 Gene

Aliases for ZNF772 Gene

  • Zinc Finger Protein 772 2 3 5

External Ids for ZNF772 Gene

Previous GeneCards Identifiers for ZNF772 Gene

  • GC19M062674
  • GC19M057982
  • GC19M054293

Summaries for ZNF772 Gene

GeneCards Summary for ZNF772 Gene

ZNF772 (Zinc Finger Protein 772) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF304.

UniProtKB/Swiss-Prot for ZNF772 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF772 Gene

Genomics for ZNF772 Gene

Regulatory Elements for ZNF772 Gene

Enhancers for ZNF772 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G057849 1.2 ENCODE 12.1 -373.1 -373090 3.0 HNRNPUL1 HDGF PKNOX1 CREB3L1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 ENSG00000269867 ZNF587 ENSG00000268912 ZSCAN1 VN1R1 LOC100419848 ZSCAN18 ENSG00000268201 LETM1P2 LOC100128398
GH19G057388 1.1 ENCODE 12.2 +87.6 87571 2.2 PKNOX1 FOXA2 WRNIP1 SIN3A DMAP1 YY1 ZNF143 FOS SP3 CEBPZ ZSCAN18 ENSG00000269696 LOC100128398 ZNF470 ZNF582-AS1 ZNF583 ZNF304 ZNF264 ZNF667 ZNF667-AS1
GH19G057476 1 ENCODE 12.8 +0.1 93 1.5 PKNOX1 FOXA2 ATF1 MLX CREB3L1 ARID4B SIN3A DMAP1 ZNF48 YY1 VN1R1 ZNF773 ZNF134 ZNF417 ZNF606 ZNF667 ENSG00000269696 ZNF71 ENSG00000268912 ZSCAN1
GH19G056594 1 ENCODE 12.1 +882.1 882130 1.4 HDGF PKNOX1 ZNF133 ARID4B SIN3A FEZF1 YBX1 GLI4 ZNF48 YY1 ZNF17 ENSG00000269696 ZNF549 ZNF773 ZNF543 U2AF2 ZFP28 ZNF667 ZNF470 FIZ1
GH19G057499 1 ENCODE 11.8 -22.7 -22652 1.9 HDGF PKNOX1 ATF1 ARID4B SIN3A DMAP1 YBX1 ZNF2 ZNF48 YY1 ZNF419 VN1R1 ZNF264 ZNF805 ZNF773 ZNF549 ZNF772 ZNF548 ZNF550 ZNF543
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF772 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF772 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000111803 70 1400 PKNOX1 FOXA2 ATF1 MLX ARID4B SIN3A DMAP1 ZNF48 YY1 ETS1

Genomic Location for ZNF772 Gene

Chromosome:
19
Start:
57,466,663 bp from pter
End:
57,477,570 bp from pter
Size:
10,908 bases
Orientation:
Minus strand

Genomic View for ZNF772 Gene

Genes around ZNF772 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF772 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF772 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF772 Gene

Proteins for ZNF772 Gene

  • Protein details for ZNF772 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q68DY9-ZN772_HUMAN
    Recommended name:
    Zinc finger protein 772
    Protein Accession:
    Q68DY9
    Secondary Accessions:
    • A6NJK9
    • B4DH56
    • B4DYS0

    Protein attributes for ZNF772 Gene

    Size:
    489 amino acids
    Molecular mass:
    55367 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF772 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF772 Gene

Post-translational modifications for ZNF772 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF772 Gene

Domains & Families for ZNF772 Gene

Gene Families for ZNF772 Gene

Protein Domains for ZNF772 Gene

Suggested Antigen Peptide Sequences for ZNF772 Gene

Graphical View of Domain Structure for InterPro Entry

Q68DY9

UniProtKB/Swiss-Prot:

ZN772_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF772: view

Function for ZNF772 Gene

Molecular function for ZNF772 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF772 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF772: view
genes like me logo Genes that share phenotypes with ZNF772: view

Animal Model Products

CRISPR Products

miRNA for ZNF772 Gene

miRTarBase miRNAs that target ZNF772

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF772 Gene

Localization for ZNF772 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF772 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF772 gene
Compartment Confidence
nucleus 5
cytosol 3

Gene Ontology (GO) - Cellular Components for ZNF772 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF772: view

Pathways & Interactions for ZNF772 Gene

SuperPathways for ZNF772 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF772: view

Pathways by source for ZNF772 Gene

2 Reactome pathways for ZNF772 Gene

Gene Ontology (GO) - Biological Process for ZNF772 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF772: view

No data available for SIGNOR curated interactions for ZNF772 Gene

Drugs & Compounds for ZNF772 Gene

No Compound Related Data Available

Transcripts for ZNF772 Gene

Unigene Clusters for ZNF772 Gene

Zinc finger protein 772:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF772 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b
SP1:
SP2: -

Relevant External Links for ZNF772 Gene

GeneLoc Exon Structure for
ZNF772
ECgene alternative splicing isoforms for
ZNF772

Expression for ZNF772 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF772 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF772 Gene:

ZNF772

SOURCE GeneReport for Unigene cluster for ZNF772 Gene:

Hs.388810

Evidence on tissue expression from TISSUES for ZNF772 Gene

  • Nervous system(4.3)
genes like me logo Genes that share expression patterns with ZNF772: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF772 Gene

Orthologs for ZNF772 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF772 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF772 34 35
  • 99.45 (n)
dog
(Canis familiaris)
Mammalia ZNF772 34 35
  • 87.16 (n)
cow
(Bos Taurus)
Mammalia ZNF772 35
  • 77 (a)
OneToOne
Species where no ortholog for ZNF772 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF772 Gene

ENSEMBL:
Gene Tree for ZNF772 (if available)
TreeFam:
Gene Tree for ZNF772 (if available)

Paralogs for ZNF772 Gene

(414) SIMAP similar genes for ZNF772 Gene using alignment to 5 proteins:

Pseudogenes.org Pseudogenes for ZNF772 Gene

genes like me logo Genes that share paralogs with ZNF772: view

Variants for ZNF772 Gene

Sequence variations from dbSNP and Humsavar for ZNF772 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs193920834 Uncertain significance 57,477,299(-) GATGG(-/GGC)CGGCG cds-indel, utr-variant-5-prime
rs1000066096 -- 57,480,521(+) GTTAT(A/G)ACCTG utr-variant-5-prime
rs1000098130 -- 57,480,926(+) TCAAA(A/T)TTTTT utr-variant-5-prime
rs1000274871 -- 57,470,535(+) CAATA(A/G)AAGCG utr-variant-3-prime
rs1000279280 -- 57,474,746(+) CCAAA(A/G)AAAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF772 Gene

Variant ID Type Subtype PubMed ID
dgv3684n100 CNV gain 25217958
esv24439 CNV gain 19812545
esv3575097 CNV gain 25503493
esv3644903 CNV gain 21293372
nsv828655 CNV gain 20364138
nsv9773 CNV gain 18304495

Variation tolerance for ZNF772 Gene

Residual Variation Intolerance Score: 73.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.82; 17.18% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF772 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF772

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF772 Gene

Disorders for ZNF772 Gene

Relevant External Links for ZNF772

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF772

No disorders were found for ZNF772 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF772 Gene

Publications for ZNF772 Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3 64
  3. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64

Products for ZNF772 Gene

Sources for ZNF772 Gene

Content
Loading form....