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Aliases for ZNF771 Gene

Aliases for ZNF771 Gene

  • Zinc Finger Protein 771 2 3
  • Mesenchymal Stem Cell Protein DSC43 3 4
  • DSC43 3

External Ids for ZNF771 Gene

Previous GeneCards Identifiers for ZNF771 Gene

  • GC16P030327
  • GC16P027980

Summaries for ZNF771 Gene

GeneCards Summary for ZNF771 Gene

ZNF771 (Zinc Finger Protein 771) is a Protein Coding gene. Among its related pathways are Gene Expression. An important paralog of this gene is ZNF501.

UniProtKB/Swiss-Prot for ZNF771 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF771 Gene

Genomics for ZNF771 Gene

Regulatory Elements for ZNF771 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF771 Gene

Chromosome:
16
Start:
30,407,297 bp from pter
End:
30,431,108 bp from pter
Size:
23,812 bases
Orientation:
Plus strand

Genomic View for ZNF771 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF771 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF771 Gene

Proteins for ZNF771 Gene

  • Protein details for ZNF771 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7L3S4-ZN771_HUMAN
    Recommended name:
    Zinc finger protein 771
    Protein Accession:
    Q7L3S4
    Secondary Accessions:
    • Q8TAQ7
    • Q9NYI6

    Protein attributes for ZNF771 Gene

    Size:
    317 amino acids
    Molecular mass:
    35702 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAF65445.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF771 Gene

Proteomics data for ZNF771 Gene at MOPED

Post-translational modifications for ZNF771 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF771 Gene

Antibody Products

No data available for DME Specific Peptides for ZNF771 Gene

Domains & Families for ZNF771 Gene

Gene Families for ZNF771 Gene

Protein Domains for ZNF771 Gene

Suggested Antigen Peptide Sequences for ZNF771 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7L3S4

UniProtKB/Swiss-Prot:

ZN771_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 8 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 8 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF771: view

Function for ZNF771 Gene

Molecular function for ZNF771 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF771 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF771: view
genes like me logo Genes that share phenotypes with ZNF771: view

Animal Model Products

CRISPR Products

miRNA for ZNF771 Gene

miRTarBase miRNAs that target ZNF771

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF771

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF771 Gene

Localization for ZNF771 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF771 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF771 Gene COMPARTMENTS Subcellular localization image for ZNF771 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF771 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF771: view

Pathways & Interactions for ZNF771 Gene

SuperPathways for ZNF771 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF771: view

Pathways by source for ZNF771 Gene

2 Reactome pathways for ZNF771 Gene

Interacting Proteins for ZNF771 Gene

Gene Ontology (GO) - Biological Process for ZNF771 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF771: view

No data available for SIGNOR curated interactions for ZNF771 Gene

Drugs & Compounds for ZNF771 Gene

No Compound Related Data Available

Transcripts for ZNF771 Gene

Unigene Clusters for ZNF771 Gene

Zinc finger protein 771:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF771

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF771 Gene

No ASD Table

Relevant External Links for ZNF771 Gene

GeneLoc Exon Structure for
ZNF771
ECgene alternative splicing isoforms for
ZNF771

Expression for ZNF771 Gene

mRNA expression in normal human tissues for ZNF771 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF771 Gene

This gene is overexpressed in Adipocyte (31.5), Lung (27.0), and Ovary (10.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF771 Gene



SOURCE GeneReport for Unigene cluster for ZNF771 Gene Hs.148584

genes like me logo Genes that share expression patterns with ZNF771: view

Protein tissue co-expression partners for ZNF771 Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF771 Gene

Orthologs for ZNF771 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF771 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF771 35
  • 91.83 (n)
  • 95.22 (a)
ZNF771 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF771 35
  • 93.69 (n)
  • 97.16 (a)
ZNF771 36
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp771 35
  • 90.54 (n)
  • 95.9 (a)
Zfp771 16
Zfp771 36
  • 96 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF771 35
  • 99.47 (n)
  • 100 (a)
ZNF771 36
  • 100 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF771 36
  • 88 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii si:ch73-92e7.6 36
  • 31 (a)
ManyToMany
si:dkey-191j3.3 36
  • 38 (a)
ManyToMany
si:dkey-20i20.10 36
  • 34 (a)
ManyToMany
si:dkey-20i20.3 36
  • 31 (a)
ManyToMany
si:dkey-20i20.7 36
  • 26 (a)
ManyToMany
si:dkey-20i20.8 36
  • 27 (a)
ManyToMany
si:dkey-20i20.9 36
  • 25 (a)
ManyToMany
zgc:173575 36
  • 42 (a)
ManyToMany
Species with no ortholog for ZNF771:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF771 Gene

ENSEMBL:
Gene Tree for ZNF771 (if available)
TreeFam:
Gene Tree for ZNF771 (if available)

Paralogs for ZNF771 Gene

Paralogs for ZNF771 Gene

(482) SIMAP similar genes for ZNF771 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF771: view

Variants for ZNF771 Gene

Sequence variations from dbSNP and Humsavar for ZNF771 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs3194599 -- 30,418,251(-) GTGCG(A/C)GCGTC reference, missense
rs4074619 -- 30,405,661(-) atagc(A/G)cagtc upstream-variant-2KB
rs4129614 -- 30,416,755(-) TGTCA(A/G)AGGGC intron-variant
rs4232893 -- 30,412,430(+) TGACC(A/G)CAAAA intron-variant
rs4286118 -- 30,414,190(+) ACCAA(C/T)AGATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF771 Gene

Variant ID Type Subtype PubMed ID
nsv905724 CNV Loss 21882294
nsv827612 CNV Gain 20364138
nsv905725 CNV Loss 21882294

Variation tolerance for ZNF771 Gene

Gene Damage Index Score: 0.89; 18.50% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF771 Gene

HapMap Linkage Disequilibrium report
ZNF771

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF771 Gene

Disorders for ZNF771 Gene

Relevant External Links for ZNF771

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF771
genes like me logo Genes that share disorders with ZNF771: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF771 Gene

Publications for ZNF771 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. Initial characterization of the human central proteome. (PMID: 21269460) Burkard T.R. … Colinge J. (BMC Syst. Biol. 2011) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67

Products for ZNF771 Gene

Sources for ZNF771 Gene

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