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Aliases for ZNF770 Gene

Aliases for ZNF770 Gene

  • Zinc Finger Protein 770 2 3
  • PRO1914 3

External Ids for ZNF770 Gene

Previous GeneCards Identifiers for ZNF770 Gene

  • GC15M033058
  • GC15M035270
  • GC15M012115

Summaries for ZNF770 Gene

GeneCards Summary for ZNF770 Gene

ZNF770 (Zinc Finger Protein 770) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding RNA polymerase II transcription factor activity. An important paralog of this gene is ZNF319.

UniProtKB/Swiss-Prot for ZNF770 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF770 Gene

Genomics for ZNF770 Gene

Regulatory Elements for ZNF770 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF770 Gene

Start:
34,978,341 bp from pter
End:
34,988,296 bp from pter
Size:
9,956 bases
Orientation:
Minus strand

Genomic View for ZNF770 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF770 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF770 Gene

Proteins for ZNF770 Gene

  • Protein details for ZNF770 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6IQ21-ZN770_HUMAN
    Recommended name:
    Zinc finger protein 770
    Protein Accession:
    Q6IQ21
    Secondary Accessions:
    • Q6ZMZ6
    • Q9NWV2

    Protein attributes for ZNF770 Gene

    Size:
    691 amino acids
    Molecular mass:
    80007 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAD18579.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF770 Gene

Proteomics data for ZNF770 Gene at MOPED

Post-translational modifications for ZNF770 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF770 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF770 Gene

Domains for ZNF770 Gene

Gene Families for ZNF770 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF770 Gene

Suggested Antigen Peptide Sequences for ZNF770 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6IQ21

UniProtKB/Swiss-Prot:

ZN770_HUMAN :
  • Q6IQ21
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 11 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF770: view

Function for ZNF770 Gene

Molecular function for ZNF770 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF770 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity IBA --
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF770: view

Animal Model Products

CRISPR Products

miRNA for ZNF770 Gene

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF770

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF770 Gene

Localization for ZNF770 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF770 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF770 Gene COMPARTMENTS Subcellular localization image for ZNF770 gene
Compartment Confidence
nucleus 4
cytosol 1

Gene Ontology (GO) - Cellular Components for ZNF770 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZNF770: view

Pathways for ZNF770 Gene

SuperPathways for ZNF770 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF770: view

Pathways by source for ZNF770 Gene

2 Reactome pathways for ZNF770 Gene

Gene Ontology (GO) - Biological Process for ZNF770 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated --
GO:0006355 regulation of transcription, DNA-templated --
GO:0006357 regulation of transcription from RNA polymerase II promoter IBA --
GO:0006366 transcription from RNA polymerase II promoter IBA --
genes like me logo Genes that share ontologies with ZNF770: view

Transcripts for ZNF770 Gene

mRNA/cDNA for ZNF770 Gene

Unigene Clusters for ZNF770 Gene

Zinc finger protein 770:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF770

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF770 Gene

No ASD Table

Relevant External Links for ZNF770 Gene

GeneLoc Exon Structure for
ZNF770
ECgene alternative splicing isoforms for
ZNF770

Expression for ZNF770 Gene

mRNA expression in normal human tissues for ZNF770 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF770 Gene

SOURCE GeneReport for Unigene cluster for ZNF770 Gene Hs.744990

genes like me logo Genes that share expressions with ZNF770: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF770 Gene

Orthologs for ZNF770 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF770 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF770 35
  • 99.66 (n)
  • 99.86 (a)
ZNF770 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF770 35
  • 87.68 (n)
  • 81.66 (a)
ZNF770 36
  • 80 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF770 35
  • 88.77 (n)
  • 84.34 (a)
ZNF770 36
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp770 35
  • 82.58 (n)
  • 77.15 (a)
Zfp770 16
Zfp770 36
  • 74 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF770 36
  • 64 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp770 35
  • 83.14 (n)
  • 76.24 (a)
chicken
(Gallus gallus)
Aves ZNF770 35
  • 65.81 (n)
  • 55.04 (a)
ZNF770 36
  • 50 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.12795 35
znf770 35
  • 54.03 (n)
  • 46.24 (a)
zebrafish
(Danio rerio)
Actinopterygii BX004873.1 36
  • 29 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta crol 36
  • 14 (a)
OneToMany
Species with no ortholog for ZNF770:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF770 Gene

ENSEMBL:
Gene Tree for ZNF770 (if available)
TreeFam:
Gene Tree for ZNF770 (if available)

Paralogs for ZNF770 Gene

Paralogs for ZNF770 Gene

Pseudogenes.org Pseudogenes for ZNF770 Gene

genes like me logo Genes that share paralogs with ZNF770: view

Variants for ZNF770 Gene

Sequence variations from dbSNP and Humsavar for ZNF770 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs1127201 -- 34,978,412(-) TTTAA(G/T)GGAAG utr-variant-3-prime
rs4923849 -- 34,981,419(+) GTAAG(C/T)TGATG synonymous-codon, reference
rs7165312 -- 34,978,795(+) ccccc(C/T)aaccc utr-variant-3-prime
rs7176128 -- 34,986,524(+) caagg(G/T)agtca intron-variant
rs7180251 -- 34,990,109(+) AGAAC(A/G)TGGTA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF770 Gene

Variant ID Type Subtype PubMed ID
nsv522411 CNV Gain 19592680
nsv827295 CNV Gain 20364138

Relevant External Links for ZNF770 Gene

HapMap Linkage Disequilibrium report
ZNF770

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF770 Gene

Disorders for ZNF770 Gene

No disorders were found for ZNF770 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF770 Gene

Publications for ZNF770 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. Defining the human deubiquitinating enzyme interaction landscape. (PMID: 19615732) Sowa M.E. … Harper J.W. (Cell 2009) 3

Products for ZNF770 Gene

Sources for ZNF770 Gene

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