Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF77 Gene

Aliases for ZNF77 Gene

  • Zinc Finger Protein 77 2 3 5
  • ZNFpT1 3 4
  • Zinc Finger Protein 77 (PT1) 2
  • PT1 3

External Ids for ZNF77 Gene

Previous GeneCards Identifiers for ZNF77 Gene

  • GC19U990110
  • GC19M002873
  • GC19M002884
  • GC19M002847
  • GC19M002701
  • GC19M002897
  • GC19M002917

Summaries for ZNF77 Gene

GeneCards Summary for ZNF77 Gene

ZNF77 (Zinc Finger Protein 77) is a Protein Coding gene. Diseases associated with ZNF77 include Tuberculous Epididymitis and Bone Squamous Cell Carcinoma. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ENSG00000196826.

UniProtKB/Swiss-Prot for ZNF77 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF77 Gene

Genomics for ZNF77 Gene

Regulatory Elements for ZNF77 Gene

Enhancers for ZNF77 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF77 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF77 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF77 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF77 Gene

2,933,218 bp from pter
2,945,279 bp from pter
12,062 bases
Minus strand

Genomic View for ZNF77 Gene

Genes around ZNF77 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF77 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF77 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF77 Gene

Proteins for ZNF77 Gene

  • Protein details for ZNF77 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 77
    Protein Accession:
    Secondary Accessions:
    • Q86XJ3
    • Q9NPP0

    Protein attributes for ZNF77 Gene

    545 amino acids
    Molecular mass:
    61964 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAA46337.1; Type=Frameshift; Positions=98, 317; Evidence={ECO:0000305};

neXtProt entry for ZNF77 Gene

Proteomics data for ZNF77 Gene at MOPED

Post-translational modifications for ZNF77 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF77 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Abcam antibodies for ZNF77
  • Santa Cruz Biotechnology (SCBT) Antibodies for ZNF77

No data available for DME Specific Peptides for ZNF77 Gene

Domains & Families for ZNF77 Gene

Gene Families for ZNF77 Gene

Protein Domains for ZNF77 Gene

Suggested Antigen Peptide Sequences for ZNF77 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF77: view

Function for ZNF77 Gene

Molecular function for ZNF77 Gene

GENATLAS Biochemistry:
zinc finger protein 77
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF77 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
genes like me logo Genes that share ontologies with ZNF77: view
genes like me logo Genes that share phenotypes with ZNF77: view

Animal Model Products

CRISPR Products

miRNA for ZNF77 Gene

miRTarBase miRNAs that target ZNF77

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF77 Gene

Localization for ZNF77 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF77 Gene

Subcellular locations from

Jensen Localization Image for ZNF77 Gene COMPARTMENTS Subcellular localization image for ZNF77 gene
Compartment Confidence
nucleus 5
cytosol 3
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for ZNF77 Gene

Pathways & Interactions for ZNF77 Gene

SuperPathways for ZNF77 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF77: view

Pathways by source for ZNF77 Gene

2 Reactome pathways for ZNF77 Gene

Interacting Proteins for ZNF77 Gene

Gene Ontology (GO) - Biological Process for ZNF77 Gene


No data available for SIGNOR curated interactions for ZNF77 Gene

Drugs & Compounds for ZNF77 Gene

No Compound Related Data Available

Transcripts for ZNF77 Gene

mRNA/cDNA for ZNF77 Gene

Unigene Clusters for ZNF77 Gene

Zinc finger protein 77:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF77 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4
SP1: -

Relevant External Links for ZNF77 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF77 Gene

mRNA expression in normal human tissues for ZNF77 Gene

Protein differential expression in normal tissues from HIPED for ZNF77 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF77 Gene

SOURCE GeneReport for Unigene cluster for ZNF77 Gene Hs.38004

genes like me logo Genes that share expression patterns with ZNF77: view

Protein tissue co-expression partners for ZNF77 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF77 Gene

Orthologs for ZNF77 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF77 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia ZNF77 35
  • 73.52 (n)
  • 60.18 (a)
ZNF77 36
  • 43 (a)
(Pan troglodytes)
Mammalia ZNF77 35
  • 98.65 (n)
  • 97.8 (a)
ZNF77 36
  • 98 (a)
(Bos Taurus)
Mammalia ZNF77 36
  • 45 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 41 (a)
-- 36
  • 45 (a)
-- 36
  • 42 (a)
-- 36
  • 39 (a)
(Mus musculus)
Mammalia Gm4723 36
  • 45 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 42 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 38 (a)
(Danio rerio)
Actinopterygii CR388132.2 36
  • 36 (a)
CT573234.2 36
  • 36 (a)
Species with no ortholog for ZNF77:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF77 Gene

Gene Tree for ZNF77 (if available)
Gene Tree for ZNF77 (if available)

Paralogs for ZNF77 Gene

(459) SIMAP similar genes for ZNF77 Gene using alignment to 2 proteins: Pseudogenes for ZNF77 Gene

genes like me logo Genes that share paralogs with ZNF77: view

Variants for ZNF77 Gene

Sequence variations from dbSNP and Humsavar for ZNF77 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs34603238 - 2,939,352(-) GGCAT(G/T)GCTGG reference, missense, utr-variant-5-prime
rs34705382 - 2,934,592(-) AAAGC(C/T)CTCCT reference, missense
rs35411355 - 2,933,749(-) ACAGC(A/G)GAGAG reference, missense
rs12610412 - 2,939,403(+) TCACG(C/G)AGTCC reference, missense, utr-variant-5-prime
rs12609268 - 2,939,398(+) AAAGA(C/T)CACGC reference, missense, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF77 Gene

Variant ID Type Subtype PubMed ID
esv2717920 CNV Deletion 23290073
esv2717921 CNV Deletion 23290073

Variation tolerance for ZNF77 Gene

Residual Variation Intolerance Score: 90.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.81; 58.38% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF77 Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF77 Gene

Disorders for ZNF77 Gene

MalaCards: The human disease database

(6) MalaCards diseases for ZNF77 Gene - From: DISEASES

Disorder Aliases PubMed IDs
tuberculous epididymitis
  • tuberculosis of epididymis
bone squamous cell carcinoma
bladder diverticulum
  • diverticulum - bladder
urogenital tuberculosis
  • genitourinary tuberculosis
acute interstitial pneumonia
  • idiopathic pulmonary fibrosis
- elite association - COSMIC cancer census association via MalaCards
Search ZNF77 in MalaCards View complete list of genes associated with diseases

Relevant External Links for ZNF77

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with ZNF77: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF77 Gene

Publications for ZNF77 Gene

  1. Chromosomal localization of four human zinc finger cDNAs. (PMID: 8478004) Huebner K. … Lania L. (Hum. Genet. 1993) 2 3 4 67
  2. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  3. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF77 Gene

Sources for ZNF77 Gene