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Aliases for ZNF77 Gene

Aliases for ZNF77 Gene

  • Zinc Finger Protein 77 2 3
  • ZNFpT1 3 4
  • Zinc Finger Protein 77 (PT1) 2
  • PT1 3

External Ids for ZNF77 Gene

Summaries for ZNF77 Gene

GeneCards Summary for ZNF77 Gene

ZNF77 (Zinc Finger Protein 77) is a Protein Coding gene. Diseases associated with ZNF77 include tuberculous epididymitis and bladder diverticulum. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF709.

UniProtKB/Swiss-Prot for ZNF77 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF77 Gene

Genomics for ZNF77 Gene

Genomic Location for ZNF77 Gene

Start:
2,915,341 bp from pter
End:
2,944,971 bp from pter
Size:
29,631 bases
Orientation:
Minus strand

Genomic View for ZNF77 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF77 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF77 Gene

Regulatory Elements for ZNF77 Gene

Proteins for ZNF77 Gene

  • Protein details for ZNF77 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q15935-ZNF77_HUMAN
    Recommended name:
    Zinc finger protein 77
    Protein Accession:
    Q15935
    Secondary Accessions:
    • Q86XJ3
    • Q9NPP0

    Protein attributes for ZNF77 Gene

    Size:
    545 amino acids
    Molecular mass:
    61964 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAA46337.1; Type=Frameshift; Positions=98, 317; Evidence={ECO:0000305};

neXtProt entry for ZNF77 Gene

Proteomics data for ZNF77 Gene at MOPED

Post-translational modifications for ZNF77 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF77 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF77 Gene

Domains for ZNF77 Gene

Gene Families for ZNF77 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF77 Gene

Suggested Antigen Peptide Sequences for ZNF77 Gene

Graphical View of Domain Structure for InterPro Entry

Q15935

UniProtKB/Swiss-Prot:

ZNF77_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q15935
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q15935
Similarity:
  • Contains 12 C2H2-type zinc fingers.:
    • Q15935
genes like me logo Genes that share domains with ZNF77: view

Function for ZNF77 Gene

Molecular function for ZNF77 Gene

GENATLAS Biochemistry: zinc finger protein 77
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF77 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF77: view

miRNA for ZNF77 Gene

miRTarBase miRNAs that target ZNF77

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF77 Gene

Localization for ZNF77 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF77 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF77 Gene COMPARTMENTS Subcellular localization image for ZNF77 gene
Compartment Confidence
nucleus 4
cytosol 3
plasma membrane 1

Gene Ontology (GO) - Cellular Components for ZNF77 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF77: view

Pathways for ZNF77 Gene

SuperPathways for ZNF77 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF77: view

Pathways by source for ZNF77 Gene

2 Reactome pathways for ZNF77 Gene

Interacting Proteins for ZNF77 Gene

Gene Ontology (GO) - Biological Process for ZNF77 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ZNF77: view

Transcripts for ZNF77 Gene

mRNA/cDNA for ZNF77 Gene

Unigene Clusters for ZNF77 Gene

Zinc finger protein 77:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF77 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4
SP1: -
SP2:

Relevant External Links for ZNF77 Gene

GeneLoc Exon Structure for
ZNF77
ECgene alternative splicing isoforms for
ZNF77

Expression for ZNF77 Gene

mRNA expression in normal human tissues for ZNF77 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF77 Gene

SOURCE GeneReport for Unigene cluster for ZNF77 Gene Hs.38004

genes like me logo Genes that share expressions with ZNF77: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF77 Gene

Orthologs for ZNF77 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF77 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF77 35
  • 98.65 (n)
  • 97.8 (a)
ZNF77 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF77 36
  • 45 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF77 35
  • 73.52 (n)
  • 60.18 (a)
ZNF77 36
  • 43 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm4723 36
  • 45 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 41 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
-- 36
  • 42 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 42 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 38 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii CR388132.2 36
  • 36 (a)
ManyToMany
CT573234.2 36
  • 36 (a)
ManyToMany
Species with no ortholog for ZNF77:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF77 Gene

ENSEMBL:
Gene Tree for ZNF77 (if available)
TreeFam:
Gene Tree for ZNF77 (if available)

Paralogs for ZNF77 Gene

Selected SIMAP similar genes for ZNF77 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for ZNF77 Gene

genes like me logo Genes that share paralogs with ZNF77: view

Variants for ZNF77 Gene

Sequence variations from dbSNP and Humsavar for ZNF77 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs2060277 -- 2,925,161(-) gctgc(C/G)tcaaa intron-variant
rs2060278 -- 2,925,067(-) aaaaa(A/T)ttttt intron-variant
rs2316869 -- 2,931,990(-) GAGAC(A/G)GAGCT intron-variant
rs2316870 -- 2,922,709(-) tggaa(C/G)gccaa intron-variant
rs2316871 -- 2,922,662(-) gcagt(A/G)agcca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF77 Gene

Variant ID Type Subtype PubMed ID
esv2717920 CNV Deletion 23290073
esv2717921 CNV Deletion 23290073

Relevant External Links for ZNF77 Gene

HapMap Linkage Disequilibrium report
ZNF77
Human Gene Mutation Database (HGMD)
ZNF77

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF77 Gene

Disorders for ZNF77 Gene

(3) University of Copenhagen DISEASES for ZNF77 Gene

genes like me logo Genes that share disorders with ZNF77: view

No data available for UniProtKB/Swiss-Prot for ZNF77 Gene

Publications for ZNF77 Gene

  1. Chromosomal localization of four human zinc finger cDNAs. (PMID: 8478004) Huebner K. … Lania L. (Hum. Genet. 1993) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for ZNF77 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF77
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF77
    • Block miRNA regulation of ZNF77 using miScript Target Protectors

    Sources for ZNF77 Gene

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