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Aliases for ZNF765 Gene

Aliases for ZNF765 Gene

  • Zinc Finger Protein 765 2 3

External Ids for ZNF765 Gene

Previous GeneCards Identifiers for ZNF765 Gene

  • GC19P058591
  • GC19P053898
  • GC19P050219

Summaries for ZNF765 Gene

GeneCards Summary for ZNF765 Gene

ZNF765 (Zinc Finger Protein 765) is a Protein Coding gene. An important paralog of this gene is ZNF860.

UniProtKB/Swiss-Prot for ZNF765 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF765 Gene

Genomics for ZNF765 Gene

Regulatory Elements for ZNF765 Gene

Transcription factor binding sites by QIAGEN in the ZNF765 gene promoter:

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF765 Gene

Start:
53,389,626 bp from pter
End:
53,430,413 bp from pter
Size:
40,788 bases
Orientation:
Plus strand

Genomic View for ZNF765 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF765 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF765 Gene

Proteins for ZNF765 Gene

  • Protein details for ZNF765 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7L2R6-ZN765_HUMAN
    Recommended name:
    Zinc finger protein 765
    Protein Accession:
    Q7L2R6
    Secondary Accessions:
    • A8MYG0
    • B4DF18
    • B7ZAI5
    • B9EIL1
    • Q9BV49

    Protein attributes for ZNF765 Gene

    Size:
    523 amino acids
    Molecular mass:
    61633 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF765 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF765 Gene

Proteomics data for ZNF765 Gene at MOPED

Post-translational modifications for ZNF765 Gene

  • Ubiquitination at Lys356
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF765 Gene

No data available for DME Specific Peptides for ZNF765 Gene

Domains for ZNF765 Gene

Gene Families for ZNF765 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF765 Gene

Suggested Antigen Peptide Sequences for ZNF765 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7L2R6

UniProtKB/Swiss-Prot:

ZN765_HUMAN :
  • Q7L2R6
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 11 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF765: view

Function for ZNF765 Gene

Molecular function for ZNF765 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF765 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF765: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF765 Gene

Localization for ZNF765 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF765 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF765 Gene COMPARTMENTS Subcellular localization image for ZNF765 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF765 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF765: view

Pathways for ZNF765 Gene

SuperPathways for ZNF765 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF765 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF765: view

No data available for Pathways by source for ZNF765 Gene

Transcripts for ZNF765 Gene

mRNA/cDNA for ZNF765 Gene

Unigene Clusters for ZNF765 Gene

Zinc finger protein 765:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF765

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF765
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF765 Gene

No ASD Table

Relevant External Links for ZNF765 Gene

GeneLoc Exon Structure for
ZNF765
ECgene alternative splicing isoforms for
ZNF765

Expression for ZNF765 Gene

mRNA expression in normal human tissues for ZNF765 Gene

SOURCE GeneReport for Unigene cluster for ZNF765 Gene Hs.685640

genes like me logo Genes that share expressions with ZNF765: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF765 Gene

Orthologs for ZNF765 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF765 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 96 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 36
  • 37 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 50 (a)
ManyToMany
Species with no ortholog for ZNF765:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF765 Gene

ENSEMBL:
Gene Tree for ZNF765 (if available)
TreeFam:
Gene Tree for ZNF765 (if available)

Paralogs for ZNF765 Gene

Selected SIMAP similar genes for ZNF765 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for ZNF765 Gene

genes like me logo Genes that share paralogs with ZNF765: view

Variants for ZNF765 Gene

Sequence variations from dbSNP and Humsavar for ZNF765 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1136060 -- 53,411,972(+) ATGTC(A/G)TCTAC utr-variant-3-prime
rs1871187 -- 53,394,701(-) CCAGC(A/G)AGGAG upstream-variant-2KB, intron-variant
rs2061771 -- 53,407,265(+) TCCTT(A/G)CATAA intron-variant
rs2061772 -- 53,407,352(+) TAAAT(A/G)TGAAG intron-variant
rs2061773 -- 53,407,659(+) CATCT(A/G)TACTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF765 Gene

Variant ID Type Subtype PubMed ID
nsv912342 CNV Gain 21882294
esv2718812 CNV Deletion 23290073
nsv912352 CNV Gain 21882294
dgv571e201 CNV Deletion 23290073
nsv458767 CNV Loss 19166990
esv8848 CNV Loss 19470904
nsv521988 CNV Loss 19592680
nsv912353 CNV Loss 21882294
nsv912354 CNV Loss 21882294
nsv912355 CNV Gain 21882294
nsv817866 CNV Gain 17921354
dgv3993n71 CNV Gain 21882294
nsv515728 CNV Gain+Loss 19592680
nsv912357 CNV Loss 21882294
nsv912358 CNV Gain+Loss 21882294
nsv9749 CNV Loss 18304495
nsv458768 CNV Loss 19166990
nsv470154 CNV Loss 18288195
nsv912360 CNV Gain 21882294
essv5683 CNV CNV 17122850
dgv1117e1 CNV Complex 17122850

Relevant External Links for ZNF765 Gene

HapMap Linkage Disequilibrium report
ZNF765

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF765 Gene

Disorders for ZNF765 Gene

Relevant External Links for ZNF765

Genetic Association Database (GAD)
ZNF765
Human Genome Epidemiology (HuGE) Navigator
ZNF765
genes like me logo Genes that share disorders with ZNF765: view

No data available for UniProtKB/Swiss-Prot for ZNF765 Gene

Publications for ZNF765 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  3. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PMID: 23000965) Povlsen L.K. … Choudhary C. (Nat. Cell Biol. 2012) 3

Products for ZNF765 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF765
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF765
    • Block miRNA regulation of ZNF765 using miScript Target Protectors

    Sources for ZNF765 Gene

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