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Aliases for ZNF765 Gene

Aliases for ZNF765 Gene

  • Zinc Finger Protein 765 2 3 5

External Ids for ZNF765 Gene

Previous GeneCards Identifiers for ZNF765 Gene

  • GC19P058591
  • GC19P053898
  • GC19P050219

Summaries for ZNF765 Gene

GeneCards Summary for ZNF765 Gene

ZNF765 (Zinc Finger Protein 765) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF860.

UniProtKB/Swiss-Prot for ZNF765 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF765 Gene

Genomics for ZNF765 Gene

Regulatory Elements for ZNF765 Gene

Enhancers for ZNF765 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF765 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the ZNF765 gene promoter:

Genomic Location for ZNF765 Gene

Chromosome:
19
Start:
53,387,860 bp from pter
End:
53,430,413 bp from pter
Size:
42,554 bases
Orientation:
Plus strand

Genomic View for ZNF765 Gene

Genes around ZNF765 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF765 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF765 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF765 Gene

Proteins for ZNF765 Gene

  • Protein details for ZNF765 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7L2R6-ZN765_HUMAN
    Recommended name:
    Zinc finger protein 765
    Protein Accession:
    Q7L2R6
    Secondary Accessions:
    • A8MYG0
    • B4DF18
    • B7ZAI5
    • B9EIL1
    • Q9BV49

    Protein attributes for ZNF765 Gene

    Size:
    523 amino acids
    Molecular mass:
    61633 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF765 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF765 Gene

Proteomics data for ZNF765 Gene at MOPED

Post-translational modifications for ZNF765 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF765 Gene

No data available for DME Specific Peptides for ZNF765 Gene

Domains & Families for ZNF765 Gene

Gene Families for ZNF765 Gene

Protein Domains for ZNF765 Gene

Suggested Antigen Peptide Sequences for ZNF765 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7L2R6

UniProtKB/Swiss-Prot:

ZN765_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 11 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 11 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF765: view

Function for ZNF765 Gene

Molecular function for ZNF765 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF765 Gene

GenomeRNAi human phenotypes for ZNF765:
genes like me logo Genes that share phenotypes with ZNF765: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF765 Gene

Localization for ZNF765 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF765 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF765 Gene COMPARTMENTS Subcellular localization image for ZNF765 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF765 Gene

Pathways & Interactions for ZNF765 Gene

SuperPathways for ZNF765 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF765 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZNF765 Gene

Drugs & Compounds for ZNF765 Gene

No Compound Related Data Available

Transcripts for ZNF765 Gene

Unigene Clusters for ZNF765 Gene

Zinc finger protein 765:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF765 Gene

No ASD Table

Relevant External Links for ZNF765 Gene

GeneLoc Exon Structure for
ZNF765
ECgene alternative splicing isoforms for
ZNF765

Expression for ZNF765 Gene

mRNA expression in normal human tissues for ZNF765 Gene

SOURCE GeneReport for Unigene cluster for ZNF765 Gene Hs.685640

genes like me logo Genes that share expression patterns with ZNF765: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF765 Gene

Orthologs for ZNF765 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF765 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 37 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 50 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 96 (a)
ManyToMany
Species with no ortholog for ZNF765:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF765 Gene

ENSEMBL:
Gene Tree for ZNF765 (if available)
TreeFam:
Gene Tree for ZNF765 (if available)

Paralogs for ZNF765 Gene

(491) SIMAP similar genes for ZNF765 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for ZNF765 Gene

genes like me logo Genes that share paralogs with ZNF765: view

Variants for ZNF765 Gene

Sequence variations from dbSNP and Humsavar for ZNF765 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10425136 - 53,408,720(+) AGTGT(A/G)GCAAG reference, missense
rs7259550 -- 53,400,102(+) ccacc(A/G)catct intron-variant
rs7259957 -- 53,407,096(+) AACCT(C/T)TGCCT intron-variant
rs7507359 -- 53,391,973(+) acctc(A/C)agtga intron-variant
rs7508095 -- 53,389,684(+) CAGCA(C/T)GCCAA utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF765 Gene

Variant ID Type Subtype PubMed ID
nsv912342 CNV Gain 21882294
esv2718812 CNV Deletion 23290073
nsv912352 CNV Gain 21882294
dgv571e201 CNV Deletion 23290073
nsv458767 CNV Loss 19166990
esv8848 CNV Loss 19470904
nsv521988 CNV Loss 19592680
nsv912353 CNV Loss 21882294
nsv912354 CNV Loss 21882294
nsv912355 CNV Gain 21882294
nsv817866 CNV Gain 17921354
dgv3993n71 CNV Gain 21882294
nsv515728 CNV Gain+Loss 19592680
nsv912357 CNV Loss 21882294
nsv912358 CNV Gain+Loss 21882294
nsv9749 CNV Loss 18304495
nsv458768 CNV Loss 19166990
nsv470154 CNV Loss 18288195
nsv912360 CNV Gain 21882294
essv5683 CNV CNV 17122850
dgv1117e1 CNV Complex 17122850

Variation tolerance for ZNF765 Gene

Residual Variation Intolerance Score: 59.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.91; 59.32% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF765 Gene

HapMap Linkage Disequilibrium report
ZNF765

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF765 Gene

Disorders for ZNF765 Gene

Relevant External Links for ZNF765

Genetic Association Database (GAD)
ZNF765
Human Genome Epidemiology (HuGE) Navigator
ZNF765
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF765

No disorders were found for ZNF765 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF765 Gene

Publications for ZNF765 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for ZNF765 Gene

Sources for ZNF765 Gene

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