Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF765 Gene

Aliases for ZNF765 Gene

  • Zinc Finger Protein 765 2 3 5

External Ids for ZNF765 Gene

Previous GeneCards Identifiers for ZNF765 Gene

  • GC19P058591
  • GC19P053898
  • GC19P050219

Summaries for ZNF765 Gene

GeneCards Summary for ZNF765 Gene

ZNF765 (Zinc Finger Protein 765) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF813.

UniProtKB/Swiss-Prot for ZNF765 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF765 Gene

Genomics for ZNF765 Gene

Regulatory Elements for ZNF765 Gene

Enhancers for ZNF765 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G053864 1.8 FANTOM5 ENCODE dbSUPER 19.6 +481.1 481055 9.8 MLX CREB3L1 AGO1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 ZNF845 ZNF765 ZNF816 ENSG00000269001 ENSG00000235681 ZNF813 TPM3P6 LENG8-AS1 MYADM ZNF525
GH19G053594 1.1 ENCODE dbSUPER 22.5 +205.4 205369 0.0 ARNT GLI4 ZNF48 ZBTB40 ZEB1 ZNF335 ZNF366 EGR1 KLF7 EGR2 ZNF525 ZNF665 ZNF28 PRPF31 ZNF347 LENG8-AS1 ZNF845 ZNF765 ENSG00000235681 ZNF320
GH19G053595 1.1 ENCODE dbSUPER 22.5 +205.3 205272 0.2 CREB3L1 ARNT GLI4 RAD21 ZNF48 ZBTB40 ZEB1 ZNF335 GLIS2 ZNF366 ZNF525 ZNF28 PRPF31 ZNF665 LENG8-AS1 ZNF845 ZNF765 ENSG00000235681 ZNF677 ENSG00000269825
GH19G053364 1.1 ENCODE 18.2 -22.2 -22170 1.6 HDGF HNRNPUL1 CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZBTB7B ZNF207 KLF13 ZNF525 ZNF808 ZNF845 ENSG00000268970 ZNF137P ZNF765 ZNF816 ENSG00000269825 ENSG00000269001 ZNF813
GH19G054018 1.6 FANTOM5 Ensembl ENCODE 12.5 +633.3 633258 6.8 PKNOX1 FOXA2 ATF1 CREB3L1 ARID4B SIN3A TCF12 GTF3C2 ZNF302 GATA2 LILRB3 ZNF845 ZNF525 ENSG00000235681 ENSG00000267265 LENG8-AS1 ZNF765 PRPF31 VSTM1 LILRA5
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF765 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the ZNF765 gene promoter:

Genomic Location for ZNF765 Gene

Chromosome:
19
Start:
53,387,860 bp from pter
End:
53,430,413 bp from pter
Size:
42,554 bases
Orientation:
Plus strand

Genomic View for ZNF765 Gene

Genes around ZNF765 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF765 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF765 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF765 Gene

Proteins for ZNF765 Gene

  • Protein details for ZNF765 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7L2R6-ZN765_HUMAN
    Recommended name:
    Zinc finger protein 765
    Protein Accession:
    Q7L2R6
    Secondary Accessions:
    • A8MYG0
    • B4DF18
    • B7ZAI5
    • B9EIL1
    • Q9BV49

    Protein attributes for ZNF765 Gene

    Size:
    523 amino acids
    Molecular mass:
    61633 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF765 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF765 Gene

Post-translational modifications for ZNF765 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF765 Gene

No data available for DME Specific Peptides for ZNF765 Gene

Domains & Families for ZNF765 Gene

Gene Families for ZNF765 Gene

Protein Domains for ZNF765 Gene

Suggested Antigen Peptide Sequences for ZNF765 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7L2R6

UniProtKB/Swiss-Prot:

ZN765_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF765: view

Function for ZNF765 Gene

Molecular function for ZNF765 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF765 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF765: view

Phenotypes for ZNF765 Gene

GenomeRNAi human phenotypes for ZNF765:
genes like me logo Genes that share phenotypes with ZNF765: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF765 Gene

Localization for ZNF765 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF765 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF765 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF765 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF765: view

Pathways & Interactions for ZNF765 Gene

SuperPathways for ZNF765 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF765 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF765: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF765 Gene

Drugs & Compounds for ZNF765 Gene

No Compound Related Data Available

Transcripts for ZNF765 Gene

mRNA/cDNA for ZNF765 Gene

Unigene Clusters for ZNF765 Gene

Zinc finger protein 765:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF765 Gene

No ASD Table

Relevant External Links for ZNF765 Gene

GeneLoc Exon Structure for
ZNF765
ECgene alternative splicing isoforms for
ZNF765

Expression for ZNF765 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF765 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF765 Gene:

ZNF765

SOURCE GeneReport for Unigene cluster for ZNF765 Gene:

Hs.685640

Evidence on tissue expression from TISSUES for ZNF765 Gene

  • Lung(4.6)
  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF765: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF765 Gene

Orthologs for ZNF765 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF765 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 96 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 50 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 37 (a)
ManyToMany
Species where no ortholog for ZNF765 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF765 Gene

ENSEMBL:
Gene Tree for ZNF765 (if available)
TreeFam:
Gene Tree for ZNF765 (if available)

Paralogs for ZNF765 Gene

(491) SIMAP similar genes for ZNF765 Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for ZNF765 Gene

genes like me logo Genes that share paralogs with ZNF765: view

Variants for ZNF765 Gene

Sequence variations from dbSNP and Humsavar for ZNF765 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000246805 -- 53,398,593(+) CTTTA(C/T)TTTAA intron-variant
rs1001132975 -- 53,398,437(+) AAAAG(A/G)TGACC intron-variant
rs1001956112 -- 53,396,088(+) GTAGG(A/G)AGAGG intron-variant
rs1002008338 -- 53,396,248(+) GGGAT(A/G)AGGGT intron-variant
rs1002204003 -- 53,404,437(+) CTCTT(C/T)AGAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF765 Gene

Variant ID Type Subtype PubMed ID
dgv3646n100 CNV loss 25217958
dgv3647n100 CNV loss 25217958
dgv530e201 CNV deletion 23290073
dgv6535n54 CNV gain 21841781
dgv6536n54 CNV gain 21841781
esv2718812 CNV deletion 23290073
esv2758770 CNV loss 17122850
esv3556588 CNV deletion 23714750
esv3574764 CNV gain 25503493
esv3583515 CNV loss 25503493
esv3644752 CNV gain 21293372
esv3644754 CNV loss 21293372
esv3644755 CNV loss 21293372
esv3893242 CNV loss 25118596
esv3893243 CNV gain 25118596
esv8848 CNV loss 19470904
nsv1055773 CNV gain 25217958
nsv1064557 CNV gain 25217958
nsv1160662 CNV deletion 26073780
nsv458767 CNV loss 19166990
nsv458768 CNV loss 19166990
nsv470154 CNV loss 18288195
nsv515728 CNV gain+loss 19592680
nsv521988 CNV loss 19592680
nsv580082 CNV loss 21841781
nsv580086 CNV loss 21841781
nsv817866 CNV gain 17921354
nsv9749 CNV loss 18304495
nsv978846 CNV duplication 23825009

Variation tolerance for ZNF765 Gene

Residual Variation Intolerance Score: 59.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.91; 59.32% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF765 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF765

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF765 Gene

Disorders for ZNF765 Gene

Relevant External Links for ZNF765

Genetic Association Database (GAD)
ZNF765
Human Genome Epidemiology (HuGE) Navigator
ZNF765
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF765

No disorders were found for ZNF765 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF765 Gene

Publications for ZNF765 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64

Products for ZNF765 Gene

Sources for ZNF765 Gene

Content
Loading form....