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Aliases for ZNF764 Gene

Aliases for ZNF764 Gene

  • Zinc Finger Protein 764 2 3

External Ids for ZNF764 Gene

Summaries for ZNF764 Gene

GeneCards Summary for ZNF764 Gene

ZNF764 (Zinc Finger Protein 764) is a Protein Coding gene. Diseases associated with ZNF764 include 16p11.2 microdeletion and thyroid hormone resistance. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF785.

UniProtKB/Swiss-Prot for ZNF764 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF764 Gene

Genomics for ZNF764 Gene

Genomic Location for ZNF764 Gene

Start:
30,553,764 bp from pter
End:
30,558,498 bp from pter
Size:
4,735 bases
Orientation:
Minus strand

Genomic View for ZNF764 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF764 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF764 Gene

Regulatory Elements for ZNF764 Gene

Proteins for ZNF764 Gene

  • Protein details for ZNF764 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96H86-ZN764_HUMAN
    Recommended name:
    Zinc finger protein 764
    Protein Accession:
    Q96H86
    Secondary Accessions:
    • A8MZF4
    • B3KSN2
    • H9KV99
    • Q9BWS1

    Protein attributes for ZNF764 Gene

    Size:
    408 amino acids
    Molecular mass:
    44943 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF764 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF764 Gene

Proteomics data for ZNF764 Gene at MOPED

Post-translational modifications for ZNF764 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF764 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF764 Gene

Domains for ZNF764 Gene

Gene Families for ZNF764 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF764 Gene

UniProtKB/Swiss-Prot:

ZN764_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q96H86
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q96H86
Similarity:
  • Contains 7 C2H2-type zinc fingers.:
    • Q96H86
genes like me logo Genes that share domains with ZNF764: view

Function for ZNF764 Gene

Molecular function for ZNF764 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF764 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF764: view

Phenotypes for ZNF764 Gene

GenomeRNAi human phenotypes for ZNF764:
genes like me logo Genes that share phenotypes with ZNF764: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF764 Gene

Localization for ZNF764 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF764 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF764 Gene COMPARTMENTS Subcellular localization image for ZNF764 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF764 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF764: view

Pathways for ZNF764 Gene

SuperPathways for ZNF764 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF764: view

Pathways by source for ZNF764 Gene

2 Reactome pathways for ZNF764 Gene

Gene Ontology (GO) - Biological Process for ZNF764 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF764: view

Transcripts for ZNF764 Gene

mRNA/cDNA for ZNF764 Gene

Unigene Clusters for ZNF764 Gene

Zinc finger protein 764:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF764 Gene

No ASD Table

Relevant External Links for ZNF764 Gene

GeneLoc Exon Structure for
ZNF764
ECgene alternative splicing isoforms for
ZNF764

Expression for ZNF764 Gene

mRNA expression in normal human tissues for ZNF764 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF764 Gene

SOURCE GeneReport for Unigene cluster for ZNF764 Gene Hs.132227

genes like me logo Genes that share expressions with ZNF764: view

Orthologs for ZNF764 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF764 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF764 36
  • 99.18 (n)
  • 99.26 (a)
ZNF764 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF764 36
  • 82.72 (n)
  • 77.15 (a)
dog
(Canis familiaris)
Mammalia -- 37
  • 34 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp747 37
  • 38 (a)
ManyToMany
Zfp764 36
  • 68.87 (n)
  • 64.55 (a)
Zfp764 16
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 63 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia LOC102553962 36
  • 70.15 (n)
  • 66.33 (a)
Species with no ortholog for ZNF764:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF764 Gene

ENSEMBL:
Gene Tree for ZNF764 (if available)
TreeFam:
Gene Tree for ZNF764 (if available)

Paralogs for ZNF764 Gene

Selected SIMAP similar genes for ZNF764 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF764: view

Variants for ZNF764 Gene

Sequence variations from dbSNP and Humsavar for ZNF764 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs8056929 -- 30,558,690(+) TGAAC(G/T)CAGGC upstream-variant-2KB
rs8059233 -- 30,555,176(+) CTAGA(C/T)AGTCA utr-variant-3-prime
rs9708652 -- 30,557,192(+) tccca(A/G)ctact intron-variant
rs11867032 -- 30,553,471(+) AGGCC(C/G)TCCTG downstream-variant-500B
rs12919681 -- 30,557,560(+) CATCA(C/G)AGCTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF764 Gene

Variant ID Type Subtype PubMed ID
nsv905727 CNV Loss 21882294

Relevant External Links for ZNF764 Gene

HapMap Linkage Disequilibrium report
ZNF764
Human Gene Mutation Database (HGMD)
ZNF764

Disorders for ZNF764 Gene

(1) University of Copenhagen DISEASES for ZNF764 Gene

genes like me logo Genes that share disorders with ZNF764: view

No data available for UniProtKB/Swiss-Prot for ZNF764 Gene

Publications for ZNF764 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. ZNF764 haploinsufficiency may explain partial glucocorticoid, androgen, and thyroid hormone resistance associated with 16p11.2 microdeletion. (PMID: 22577170) Kino T. … Stratakis C.A. (J. Clin. Endocrinol. Metab. 2012) 2 3
  4. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF764 Gene

Sources for ZNF764 Gene

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