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Aliases for ZNF764 Gene

Aliases for ZNF764 Gene

  • Zinc Finger Protein 764 2 3 5

External Ids for ZNF764 Gene

Previous GeneCards Identifiers for ZNF764 Gene

  • GC16M030473
  • GC16M028128

Summaries for ZNF764 Gene

GeneCards Summary for ZNF764 Gene

ZNF764 (Zinc Finger Protein 764) is a Protein Coding gene. Diseases associated with ZNF764 include Thyroid Hormone Resistance. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF785.

UniProtKB/Swiss-Prot for ZNF764 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF764 Gene

Genomics for ZNF764 Gene

Regulatory Elements for ZNF764 Gene

Enhancers for ZNF764 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF764 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF764 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF764 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF764 Gene

30,553,764 bp from pter
30,558,498 bp from pter
4,735 bases
Minus strand

Genomic View for ZNF764 Gene

Genes around ZNF764 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF764 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF764 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF764 Gene

Proteins for ZNF764 Gene

  • Protein details for ZNF764 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 764
    Protein Accession:
    Secondary Accessions:
    • A8MZF4
    • B3KSN2
    • H9KV99
    • Q9BWS1

    Protein attributes for ZNF764 Gene

    408 amino acids
    Molecular mass:
    44943 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF764 Gene


neXtProt entry for ZNF764 Gene

Proteomics data for ZNF764 Gene at MOPED

Post-translational modifications for ZNF764 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF764 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF764 Gene

Domains & Families for ZNF764 Gene

Gene Families for ZNF764 Gene

Protein Domains for ZNF764 Gene

Suggested Antigen Peptide Sequences for ZNF764 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 7 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 7 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF764: view

Function for ZNF764 Gene

Molecular function for ZNF764 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF764 Gene

genes like me logo Genes that share phenotypes with ZNF764: view

Animal Model Products

CRISPR Products

miRNA for ZNF764 Gene

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF764 Gene

Localization for ZNF764 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF764 Gene

Subcellular locations from

Jensen Localization Image for ZNF764 Gene COMPARTMENTS Subcellular localization image for ZNF764 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF764 Gene

Pathways & Interactions for ZNF764 Gene

SuperPathways for ZNF764 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF764: view

Pathways by source for ZNF764 Gene

2 Reactome pathways for ZNF764 Gene

Gene Ontology (GO) - Biological Process for ZNF764 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF764: view

No data available for SIGNOR curated interactions for ZNF764 Gene

Drugs & Compounds for ZNF764 Gene

No Compound Related Data Available

Transcripts for ZNF764 Gene

mRNA/cDNA for ZNF764 Gene

Unigene Clusters for ZNF764 Gene

Zinc finger protein 764:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF764 Gene

No ASD Table

Relevant External Links for ZNF764 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF764 Gene

mRNA expression in normal human tissues for ZNF764 Gene

Protein differential expression in normal tissues from HIPED for ZNF764 Gene

This gene is overexpressed in Adipocyte (68.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF764 Gene

SOURCE GeneReport for Unigene cluster for ZNF764 Gene Hs.132227

genes like me logo Genes that share expression patterns with ZNF764: view

Protein tissue co-expression partners for ZNF764 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF764 Gene

Orthologs for ZNF764 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF764 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF764 35
  • 82.72 (n)
  • 77.15 (a)
(Mus musculus)
Mammalia Zfp764 35
  • 68.87 (n)
  • 64.55 (a)
Zfp764 16
Zfp747 36
  • 38 (a)
(Pan troglodytes)
Mammalia ZNF764 35
  • 99.18 (n)
  • 99.26 (a)
ZNF764 36
  • 99 (a)
(Rattus norvegicus)
Mammalia LOC102553962 35
  • 70.15 (n)
  • 66.33 (a)
(Canis familiaris)
Mammalia -- 36
  • 34 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 63 (a)
Species with no ortholog for ZNF764:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF764 Gene

Gene Tree for ZNF764 (if available)
Gene Tree for ZNF764 (if available)

Paralogs for ZNF764 Gene

(313) SIMAP similar genes for ZNF764 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF764: view

Variants for ZNF764 Gene

Sequence variations from dbSNP and Humsavar for ZNF764 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs17850402 - 30,555,426(+) TGTGG(A/G)CTGCC reference, missense
rs9708652 -- 30,557,192(+) tccca(A/G)ctact intron-variant
rs13335784 -- 30,559,801(+) tttct(A/G)tacaa upstream-variant-2KB
rs61744716 -- 30,558,028(+) CGTCC(C/T)GGTAC reference, missense
rs78345703 -- 30,553,592(+) TGTTG(A/G)CTGAT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ZNF764 Gene

Variant ID Type Subtype PubMed ID
nsv905727 CNV Loss 21882294

Variation tolerance for ZNF764 Gene

Residual Variation Intolerance Score: 84.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.73; 57.63% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF764 Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF764 Gene

Disorders for ZNF764 Gene

MalaCards: The human disease database

(1) MalaCards diseases for ZNF764 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
thyroid hormone resistance
  • thyroid hormone resistance syndrome
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for ZNF764

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with ZNF764: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF764 Gene

Publications for ZNF764 Gene

  1. ZNF764 haploinsufficiency may explain partial glucocorticoid, androgen, and thyroid hormone resistance associated with 16p11.2 microdeletion. (PMID: 22577170) Kino T. … Stratakis C.A. (J. Clin. Endocrinol. Metab. 2012) 2 3 67
  2. A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. (PMID: 24104479) Vizeacoumar F.J. … Moffat J. (Mol. Syst. Biol. 2013) 3
  3. Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. (PMID: 20562864) Nozawa R.S. … Obuse C. (Nat. Cell Biol. 2010) 3
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3

Products for ZNF764 Gene

Sources for ZNF764 Gene