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Aliases for ZNF763 Gene

Aliases for ZNF763 Gene

  • Zinc Finger Protein 763 2 3 5
  • Zinc Finger Protein 440 Like 3
  • DNA-Binding Protein 3
  • ZNF440L 3
  • ZNF 3

External Ids for ZNF763 Gene

Previous GeneCards Identifiers for ZNF763 Gene

  • GC19P011938
  • GC19P012099
  • GC19P012100
  • GC19P011650
  • GC19P012050

Summaries for ZNF763 Gene

GeneCards Summary for ZNF763 Gene

ZNF763 (Zinc Finger Protein 763) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription cofactor activity. An important paralog of this gene is ENSG00000196826.

UniProtKB/Swiss-Prot for ZNF763 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF763 Gene

Genomics for ZNF763 Gene

Regulatory Elements for ZNF763 Gene

Promoters for ZNF763 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF763 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF763 Gene

Chromosome:
19
Start:
11,965,037 bp from pter
End:
11,980,399 bp from pter
Size:
15,363 bases
Orientation:
Plus strand

Genomic View for ZNF763 Gene

Genes around ZNF763 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF763 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF763 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF763 Gene

Proteins for ZNF763 Gene

  • Protein details for ZNF763 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q0D2J5-ZN763_HUMAN
    Recommended name:
    Zinc finger protein 763
    Protein Accession:
    Q0D2J5
    Secondary Accessions:
    • B3KRU3
    • B4DRE7

    Protein attributes for ZNF763 Gene

    Size:
    394 amino acids
    Molecular mass:
    46099 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF763 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF763 Gene

Proteomics data for ZNF763 Gene at MOPED

Post-translational modifications for ZNF763 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF763 Gene

No data available for DME Specific Peptides for ZNF763 Gene

Domains & Families for ZNF763 Gene

Gene Families for ZNF763 Gene

Protein Domains for ZNF763 Gene

Suggested Antigen Peptide Sequences for ZNF763 Gene

Graphical View of Domain Structure for InterPro Entry

Q0D2J5

UniProtKB/Swiss-Prot:

ZN763_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 8 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 8 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF763: view

Function for ZNF763 Gene

Molecular function for ZNF763 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF763 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
genes like me logo Genes that share ontologies with ZNF763: view

Phenotypes for ZNF763 Gene

genes like me logo Genes that share phenotypes with ZNF763: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF763 Gene

Localization for ZNF763 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF763 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF763 Gene COMPARTMENTS Subcellular localization image for ZNF763 gene
Compartment Confidence
extracellular 5
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF763 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 23376485
genes like me logo Genes that share ontologies with ZNF763: view

Pathways & Interactions for ZNF763 Gene

SuperPathways for ZNF763 Gene

No Data Available

Interacting Proteins for ZNF763 Gene

Gene Ontology (GO) - Biological Process for ZNF763 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF763: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF763 Gene

Drugs & Compounds for ZNF763 Gene

No Compound Related Data Available

Transcripts for ZNF763 Gene

mRNA/cDNA for ZNF763 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF763 Gene

Zinc finger protein 763:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF763 Gene

No ASD Table

Relevant External Links for ZNF763 Gene

GeneLoc Exon Structure for
ZNF763
ECgene alternative splicing isoforms for
ZNF763

Expression for ZNF763 Gene

mRNA expression in normal human tissues for ZNF763 Gene

Protein differential expression in normal tissues from HIPED for ZNF763 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF763 Gene



SOURCE GeneReport for Unigene cluster for ZNF763 Gene Hs.646386

genes like me logo Genes that share expression patterns with ZNF763: view

Protein tissue co-expression partners for ZNF763 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF763 Gene

Orthologs for ZNF763 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF763 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 98 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 36
  • 39 (a)
ManyToMany
Species with no ortholog for ZNF763:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF763 Gene

ENSEMBL:
Gene Tree for ZNF763 (if available)
TreeFam:
Gene Tree for ZNF763 (if available)

Paralogs for ZNF763 Gene

(517) SIMAP similar genes for ZNF763 Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with ZNF763: view

Variants for ZNF763 Gene

Sequence variations from dbSNP and Humsavar for ZNF763 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs7254529 -, - 11,978,894(+) GTAGT(C/T)ACAGA reference, missense
rs590962 -- 11,973,736(+) ttttt(A/T)aaGAC intron-variant
rs453805 -- 11,976,130(+) GGGTA(C/G)CTATC intron-variant
rs279141 -- 11,979,239(+) TTTCA(A/G)TATCA utr-variant-3-prime
rs279142 -- 11,979,950(+) AATAC(A/C)TGAAA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF763 Gene

Variant ID Type Subtype PubMed ID
nsv525966 CNV Gain 19592680
nsv911068 CNV Gain 21882294
nsv911069 CNV Loss 21882294
esv2718189 CNV Deletion 23290073

Variation tolerance for ZNF763 Gene

Residual Variation Intolerance Score: 95.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.87; 48.39% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF763 Gene

HapMap Linkage Disequilibrium report
ZNF763

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF763 Gene

Disorders for ZNF763 Gene

Relevant External Links for ZNF763

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF763

No disorders were found for ZNF763 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF763 Gene

Publications for ZNF763 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3
  4. A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells. (PMID: 23284306) Xie L. … Green M.R. (PLoS Genet. 2012) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF763 Gene

Sources for ZNF763 Gene

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