ZNF761 Gene
protein-coding GIFtS: 37
GCID: GC19P053936
|
|
zinc finger protein 761
| |
Aliases
for ZNF761 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 7611 2 | | KIAA20331 3 | | FLJ162311 | | FLJ353331 | | ZNF4682 | | Zinc Finger Protein 4682 |
Export aliases for ZNF761 gene to outside databasesPrevious GC identifers: GC19P058645 GC19P050255 |
Summaries
for ZNF761 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN761_HUMAN, Q86XN6Function: May be involved in transcriptional regulation (By similarity)
|
Genomic Views
for ZNF761 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF761 gene promoter:
IRF-1 Ik-3 MRF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF761
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF761 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.42 Ensembl cytogenetic band: 19q13.42 HGNC cytogenetic band: 19q13.42ZNF761 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P053936: view genomic region
(about GC identifiers)
Start:
|
53,935,227 bp from pter |
End:
|
53,961,515 bp from pter |
Size:
|
26,289 bases |
Orientation:
|
plus strand |
|
Proteins
for ZNF761 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN761_HUMAN, Q86XN6 (See
protein sequence)Recommended Name: Zinc finger protein 761 Size: 746 amino acids; 87719 Da
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=BAC67660.2; Type=Erroneous initiation;
Secondary accessions: Q6ZNB9Alternative splicing: 3 isoforms: Q86XN6-1 Q86XN6-2 Q86XN6-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZNF761: NX_Q86XN6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86XN6
ZNF761 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_001008401.3
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF761 for ontologies About GeneDecksing
ZNF761 Antibody Products:
Assay Products for ZNF761: |
Protein
Domains /
Families
for ZNF761 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF761 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q86XN6ProtoNet protein and cluster: Q86XN6 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN761_HUMAN, Q86XN6Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 19 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF761 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN761_HUMAN, Q86XN6Function: May be involved in transcriptional regulation (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF761 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF761 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF761 (NM_001008401) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF761 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF761 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF761 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF761 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF761 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF761
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF761 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF761 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF761
Search CenterWatch for drugs/clinical trials and news about ZNF761 / ZN761
|
Transcripts
for ZNF761 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF761 gene: NM_001008401.3 Unigene Cluster for ZNF761: Zinc finger protein 761 Hs.433293 [show with all ESTs]Unigene Representative Sequence: NM_0010084017 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000447129(uc002qbr.2) ENST00000429310(uc010ydy.2) ENST00000366293
ENST00000334095(uc002qbt.2) ENST00000454407(uc010eqp.3) ENST00000396407
ENST00000432094
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF761 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF761 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF761 (NM_001008401) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF761 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF761 |
Additional cDNA sequence: AB107355.2 AK092652.1 AK094777.1 AK131281.1 BC047783.1 BC061910.1 BC071639.1 BC103708.1 BX647962.1 NR_003148.3 24/25 DOTS entries (see all 25): DT.95132340 DT.100844587 DT.95366663 DT.95357463 DT.100033392 DT.121462127 DT.445532 DT.121462066 DT.102839359 DT.121462057 DT.92417373 DT.100015972 DT.100637745 DT.100799004 DT.121462030 DT.40214422 DT.75108162 DT.92416069 DT.100654735 DT.102819730 DT.121462295 DT.70104669 DT.92414322 DT.92418937 24/35 AceView cDNA sequences (see all 35): CB160567 AX747654 AK092652 CB160467 CR610971 BF842720 CB160471 BF445321 BF439005 AK094777 AL701693 BX507092 CB990719 AI953653 BG621675 AI467893 BX647962 BX487687 BC047783 AL708372 AV716170 CD655581 BX641571 CB122362
GeneLoc Exon Structure
|
Expression
for ZNF761 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF761 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AACCTGGGAA
About this image
SOURCE GeneReport for Unigene cluster: Hs.433293
SABiosciences Custom PCR Arrays for ZNF761
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF761
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF761 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF761 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF761 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF761 |
Orthologs
for ZNF761 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for ZNF761 gene from 1/2 species (see all 2) About this table
ENSEMBL Gene Tree for ZNF761 (if available)
TreeFam Gene Tree for ZNF761 (if available) |
Paralogs
for ZNF761 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ZNF761 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF761 (53935227 - 53961515 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for ZNF761
6 CNVs: 89305 29695 102873 3198 53869 63131 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for ZNF761 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF761 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF761 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF761) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
|
External Searches for ZNF761 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF761 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF761 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZNF761 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF761 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF761 gene:
Search GeneIP for patents involving ZNF761
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF761 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF761 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF761 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF761 | | OriGene 3'-UTR Clone for ZNF761 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF761 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF761 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF761 | | OriGene Custom Protein Services for ZNF761 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF761 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF761 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF761 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF761 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF761 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF761 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ZNF761 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ZNF761 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF761 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF761 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF761 |
|
|
|
|
