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Aliases for ZNF761 Gene

Aliases for ZNF761 Gene

  • Zinc Finger Protein 761 2 3
  • Zinc Finger Protein 468 3
  • KIAA2033 4
  • ZNF468 3

External Ids for ZNF761 Gene

Previous GeneCards Identifiers for ZNF761 Gene

  • GC19P058645
  • GC19P053936
  • GC19P050255

Summaries for ZNF761 Gene

GeneCards Summary for ZNF761 Gene

ZNF761 (Zinc Finger Protein 761) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression.

UniProtKB/Swiss-Prot for ZNF761 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF761 Gene

Genomics for ZNF761 Gene

Regulatory Elements for ZNF761 Gene

Transcription factor binding sites by QIAGEN in the ZNF761 gene promoter:

Genomic Location for ZNF761 Gene

Start:
53,431,974 bp from pter
End:
53,458,261 bp from pter
Size:
26,288 bases
Orientation:
Plus strand

Genomic View for ZNF761 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF761 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF761 Gene

Proteins for ZNF761 Gene

  • Protein details for ZNF761 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86XN6-ZN761_HUMAN
    Recommended name:
    Zinc finger protein 761
    Protein Accession:
    Q86XN6
    Secondary Accessions:
    • Q6ZNB9

    Protein attributes for ZNF761 Gene

    Size:
    746 amino acids
    Molecular mass:
    87719 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC67660.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF761 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF761 Gene

Proteomics data for ZNF761 Gene at MOPED

Post-translational modifications for ZNF761 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF761 Gene

No data available for DME Specific Peptides for ZNF761 Gene

Domains for ZNF761 Gene

Gene Families for ZNF761 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF761 Gene

Suggested Antigen Peptide Sequences for ZNF761 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q86XN6

UniProtKB/Swiss-Prot:

ZN761_HUMAN :
  • Q86XN6
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 19 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF761: view

Function for ZNF761 Gene

Molecular function for ZNF761 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF761 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF761: view

Animal Model Products

CRISPR Products

miRNA for ZNF761 Gene

miRTarBase miRNAs that target ZNF761

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF761 Gene

Localization for ZNF761 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF761 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF761 Gene COMPARTMENTS Subcellular localization image for ZNF761 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF761 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF761: view

Pathways for ZNF761 Gene

SuperPathways for ZNF761 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF761: view

Pathways by source for ZNF761 Gene

2 Reactome pathways for ZNF761 Gene

Interacting Proteins for ZNF761 Gene

Gene Ontology (GO) - Biological Process for ZNF761 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF761: view

Transcripts for ZNF761 Gene

Unigene Clusters for ZNF761 Gene

Zinc finger protein 761:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF761

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF761
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF761 Gene

No ASD Table

Relevant External Links for ZNF761 Gene

GeneLoc Exon Structure for
ZNF761
ECgene alternative splicing isoforms for
ZNF761

Expression for ZNF761 Gene

mRNA expression in normal human tissues for ZNF761 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for ZNF761 Gene

SOURCE GeneReport for Unigene cluster for ZNF761 Gene Hs.433293

genes like me logo Genes that share expressions with ZNF761: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF761 Gene

Orthologs for ZNF761 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for ZNF761 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF761 35
  • 98.66 (n)
  • 98.12 (a)
mouse
(Mus musculus)
Mammalia Gm13157 16
Zfp51 35
  • 63.98 (n)
  • 48.94 (a)
rat
(Rattus norvegicus)
Mammalia Znf761 35
  • 63.75 (n)
  • 48.45 (a)
Species with no ortholog for ZNF761:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF761 Gene

ENSEMBL:
Gene Tree for ZNF761 (if available)
TreeFam:
Gene Tree for ZNF761 (if available)

Paralogs for ZNF761 Gene

Selected SIMAP similar genes for ZNF761 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF761: view

No data available for Paralogs for ZNF761 Gene

Variants for ZNF761 Gene

Sequence variations from dbSNP and Humsavar for ZNF761 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1984432 - 53,455,009(+) AGTCT(A/G)TCCAC missense, reference
rs2617725 -- 53,456,900(-) TAAGC(C/T)TTCTC utr-variant-3-prime
rs2617726 - 53,456,314(-) ATTCT(C/G)TTCAG missense, reference
rs2617727 -- 53,452,342(-) gcatg(C/G)ccagc intron-variant
rs2617728 -- 53,452,304(-) ggttt(C/T)accac intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF761 Gene

Variant ID Type Subtype PubMed ID
nsv912342 CNV Gain 21882294
esv2718812 CNV Deletion 23290073
nsv912352 CNV Gain 21882294
dgv571e201 CNV Deletion 23290073
nsv458767 CNV Loss 19166990
esv8848 CNV Loss 19470904
nsv521988 CNV Loss 19592680
nsv912353 CNV Loss 21882294
nsv912355 CNV Gain 21882294
dgv3993n71 CNV Gain 21882294
nsv515728 CNV Gain+Loss 19592680
nsv912357 CNV Loss 21882294
nsv912358 CNV Gain+Loss 21882294
nsv458768 CNV Loss 19166990
nsv470154 CNV Loss 18288195
nsv912360 CNV Gain 21882294
essv5683 CNV CNV 17122850
dgv1117e1 CNV Complex 17122850
dgv3994n71 CNV Gain 21882294
nsv912362 CNV Loss 21882294
dgv3995n71 CNV Gain+Loss 21882294
esv2491793 CNV Deletion 19546169
nsv912369 CNV Gain 21882294
dgv3996n71 CNV Gain 21882294
nsv470156 CNV Gain 18288195
dgv431n27 CNV Gain 19166990
esv2718823 CNV Deletion 23290073
dgv661e199 CNV Deletion 23128226
dgv78e19 CNV Loss 19470904
nsv912376 CNV Loss 21882294
nsv912378 CNV Gain 21882294
dgv3997n71 CNV Gain 21882294
nsv912380 CNV Loss 21882294
dgv3998n71 CNV Gain 21882294

Relevant External Links for ZNF761 Gene

HapMap Linkage Disequilibrium report
ZNF761

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF761 Gene

Disorders for ZNF761 Gene

No disorders were found for ZNF761 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF761 Gene

Publications for ZNF761 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  4. A whole genome screen for HIV restriction factors. (PMID: 22082156) Liu L. … McKnight A. (Retrovirology 2011) 3
  5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3

Products for ZNF761 Gene

Sources for ZNF761 Gene

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