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Aliases for ZNF76 Gene

Aliases for ZNF76 Gene

  • Zinc Finger Protein 76 2 3
  • D6S229E 3 4 6
  • Zinc Finger Protein 76 (Expressed In Testis) 2 3
  • Zinc Finger Protein 523 3 4
  • ZNF523 3 4
  • Zfp523 3

External Ids for ZNF76 Gene

Previous Symbols for ZNF76 Gene

  • D6S229E

Summaries for ZNF76 Gene

GeneCards Summary for ZNF76 Gene

ZNF76 (Zinc Finger Protein 76) is a Protein Coding gene. An important paralog of this gene is ZIC4.

UniProtKB/Swiss-Prot for ZNF76 Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZNF76 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF76 Gene

Genomics for ZNF76 Gene

Genomic Location for ZNF76 Gene

Start:
35,258,909 bp from pter
End:
35,295,985 bp from pter
Size:
37,077 bases
Orientation:
Plus strand

Genomic View for ZNF76 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF76 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF76 Gene

Regulatory Elements for ZNF76 Gene

Proteins for ZNF76 Gene

  • Protein details for ZNF76 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P36508-ZNF76_HUMAN
    Recommended name:
    Zinc finger protein 76
    Protein Accession:
    P36508
    Secondary Accessions:
    • Q9BQB2

    Protein attributes for ZNF76 Gene

    Size:
    570 amino acids
    Molecular mass:
    61831 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF76 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF76 Gene

Proteomics data for ZNF76 Gene at MOPED

Post-translational modifications for ZNF76 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF76 Gene

No data available for DME Specific Peptides for ZNF76 Gene

Domains for ZNF76 Gene

Gene Families for ZNF76 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF76 Gene

UniProtKB/Swiss-Prot:

ZNF76_HUMAN
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • P36508
Similarity:
  • Contains 7 C2H2-type zinc fingers.:
    • P36508
genes like me logo Genes that share domains with ZNF76: view

Function for ZNF76 Gene

Molecular function for ZNF76 Gene

GENATLAS Biochemistry: zinc finger protein 76 (C2H2 type,Kruppel-like),transactivator protein,DNA protein related to Xenopus laevis STAF and ZNF143
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF76 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF76: view

Phenotypes for ZNF76 Gene

genes like me logo Genes that share phenotypes with ZNF76: view

miRNA for ZNF76 Gene

miRTarBase miRNAs that target ZNF76

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF76 Gene

Localization for ZNF76 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF76 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF76 Gene COMPARTMENTS Subcellular localization image for ZNF76 gene
Compartment Confidence
cytoskeleton 3
cytosol 3
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF76 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF76: view

Pathways for ZNF76 Gene

SuperPathways for ZNF76 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF76 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006357 regulation of transcription from RNA polymerase II promoter TAS 9705341
GO:0006359 regulation of transcription from RNA polymerase III promoter TAS 9705341
genes like me logo Genes that share ontologies with ZNF76: view

No data available for Pathways by source for ZNF76 Gene

Transcripts for ZNF76 Gene

Unigene Clusters for ZNF76 Gene

Zinc finger protein 76:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF76 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b · 13c · 13d ^ 14 ^ 15 ^
SP1: - - -
SP2: - - - -
SP3: - - -
SP4: - - - - - -
SP5: - - -
SP6: -
SP7: - - -
SP8: -
SP9: - -
SP10:

ExUns: 16 ^ 17
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:

Relevant External Links for ZNF76 Gene

GeneLoc Exon Structure for
ZNF76
ECgene alternative splicing isoforms for
ZNF76

Expression for ZNF76 Gene

mRNA expression in normal human tissues for ZNF76 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF76 Gene

SOURCE GeneReport for Unigene cluster for ZNF76 Gene Hs.388024

mRNA Expression by UniProt/SwissProt for ZNF76 Gene

P36508-ZNF76_HUMAN
Tissue specificity: Testis
genes like me logo Genes that share expressions with ZNF76: view

Orthologs for ZNF76 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF76 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF76 36
  • 99.24 (n)
  • 98.95 (a)
ZNF76 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF76 36
  • 90.92 (n)
  • 93.5 (a)
ZNF76 37
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF76 36
  • 90.76 (n)
  • 94.74 (a)
ZNF76 37
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp523 36
  • 88.91 (n)
  • 92.43 (a)
Zfp523 16
Zfp523 37
  • 92 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF76 37
  • 92 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp523 36
  • 89.08 (n)
  • 92.25 (a)
chicken
(Gallus gallus)
Aves ZNF76 36
  • 68.25 (n)
  • 62.36 (a)
ZNF76 37
  • 63 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii zgc:153635 36
  • 66.14 (n)
  • 67.06 (a)
ZNF76 37
  • 63 (a)
OneToOne
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.8333 36
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 52 (a)
OneToMany
Species with no ortholog for ZNF76:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF76 Gene

ENSEMBL:
Gene Tree for ZNF76 (if available)
TreeFam:
Gene Tree for ZNF76 (if available)

Paralogs for ZNF76 Gene

Paralogs for ZNF76 Gene

Selected SIMAP similar genes for ZNF76 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF76: view

Variants for ZNF76 Gene

Sequence variations from dbSNP and Humsavar for ZNF76 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs1194 -- 35,295,778(+) GGCTG(A/G)AGAAA utr-variant-3-prime, nc-transcript-variant
rs729925 -- 35,289,157(+) CTCCT(A/C)GACCT intron-variant
rs743965 -- 35,286,430(+) GGGAA(A/G)GATGG intron-variant
rs763157 -- 35,290,762(+) GTTCT(A/C)GTTCT intron-variant
rs965272 -- 35,294,213(-) TTCCA(A/G)AGATA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF76 Gene

Variant ID Type Subtype PubMed ID
dgv1939e1 CNV Complex 17122850
esv2750621 CNV Gain 17666407
esv32738 CNV Gain 17666407

Relevant External Links for ZNF76 Gene

HapMap Linkage Disequilibrium report
ZNF76

Disorders for ZNF76 Gene

Relevant External Links for ZNF76

Genetic Association Database (GAD)
ZNF76
Human Genome Epidemiology (HuGE) Navigator
ZNF76
genes like me logo Genes that share disorders with ZNF76: view

No data available for UniProtKB/Swiss-Prot for ZNF76 Gene

Publications for ZNF76 Gene

  1. A testis-expressed Zn finger gene (ZNF76) in human 6p21.3 centromeric to the MHC is closely linked to the human homolog of the T-complex gene tcp-11. (PMID: 1427894) Ragoussis J. … Trowsdale J. (Genomics 1992) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Many sequence variants affecting diversity of adult human height. (PMID: 18391951) Gudbjartsson D.F. … Stefansson K. (Nat. Genet. 2008) 3 49
  4. Risk of meningioma and common variation in genes related to innate immunity. (PMID: 20406964) Rajaraman P. … Inskip P.D. (Cancer Epidemiol. Biomarkers Prev. 2010) 3 49
  5. Polymorphisms in innate immunity genes and risk of childhood leukemia. (PMID: 20438785) Han S. … Kang D. (Hum. Immunol. 2010) 3 49

Products for ZNF76 Gene

Sources for ZNF76 Gene

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