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Aliases for ZNF75D Gene

Aliases for ZNF75D Gene

  • Zinc Finger Protein 75D 2 3
  • ZNF75 3 4 6
  • Zinc Finger Protein 75 3 4
  • Zinc Finger Protein 82 3 4
  • ZNF82 3 4
  • Zinc Finger Protein 75 (D8C6) 2
  • ZKSCAN24 3
  • ZSCAN28 3
  • D8C6 3

External Ids for ZNF75D Gene

Previous HGNC Symbols for ZNF75D Gene

  • ZNF82
  • ZNF75

Previous GeneCards Identifiers for ZNF75D Gene

  • GC0XM134248
  • GC0XM134384
  • GC0XM123779

Summaries for ZNF75D Gene

Entrez Gene Summary for ZNF75D Gene

  • This gene encodes a protein that likely functions as a transcription factor. The protein, which belongs to the ZNF75 family, includes an N-terminal SCAN domain, a KRAB box, and five C2H2-type zinc finger motifs. Another functional gene belonging to this family is located on chromosome 16, while pseudogenes have been identified on chromosomes 11 and 12. Alternative splicing results in multiple transcripts variants. [provided by RefSeq, Jun 2010]

GeneCards Summary for ZNF75D Gene

ZNF75D (Zinc Finger Protein 75D) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF75A.

UniProtKB/Swiss-Prot for ZNF75D Gene

  • May be involved in transcriptional regulation

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF75D Gene

Genomics for ZNF75D Gene

Regulatory Elements for ZNF75D Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF75D Gene

Start:
135,248,920 bp from pter
End:
135,344,109 bp from pter
Size:
95,190 bases
Orientation:
Minus strand

Genomic View for ZNF75D Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF75D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF75D Gene

Proteins for ZNF75D Gene

  • Protein details for ZNF75D Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P51815-ZN75D_HUMAN
    Recommended name:
    Zinc finger protein 75D
    Protein Accession:
    P51815
    Secondary Accessions:
    • A6NK62
    • B3KRI7
    • Q5JPG0
    • Q6LDE0

    Protein attributes for ZNF75D Gene

    Size:
    510 amino acids
    Molecular mass:
    59298 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF75D Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF75D Gene

Proteomics data for ZNF75D Gene at MOPED

Post-translational modifications for ZNF75D Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF75D Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF75D Gene

Domains for ZNF75D Gene

Gene Families for ZNF75D Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF75D Gene

Graphical View of Domain Structure for InterPro Entry

P51815

UniProtKB/Swiss-Prot:

ZN75D_HUMAN :
  • P51815
Domain:
  • Contains 1 KRAB domain.
  • Contains 1 SCAN box domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 5 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF75D: view

Function for ZNF75D Gene

Molecular function for ZNF75D Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF75D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IEA --
GO:0008270 zinc ion binding NAS 8288223
GO:0046872 metal ion binding --
genes like me logo Genes that share ontologies with ZNF75D: view

Phenotypes for ZNF75D Gene

GenomeRNAi human phenotypes for ZNF75D:
genes like me logo Genes that share phenotypes with ZNF75D: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF75D Gene

Localization for ZNF75D Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF75D Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF75D Gene COMPARTMENTS Subcellular localization image for ZNF75D gene
Compartment Confidence
nucleus 5
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for ZNF75D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF75D: view

Pathways for ZNF75D Gene

SuperPathways for ZNF75D Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF75D: view

Pathways by source for ZNF75D Gene

2 Reactome pathways for ZNF75D Gene

Interacting Proteins for ZNF75D Gene

Gene Ontology (GO) - Biological Process for ZNF75D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF75D: view

Compounds for ZNF75D Gene

(1) HMDB Compounds for ZNF75D Gene

Compound Synonyms Cas Number PubMed IDs
Zinc
  • Zinc
7440-66-6
genes like me logo Genes that share compounds with ZNF75D: view

Transcripts for ZNF75D Gene

Unigene Clusters for ZNF75D Gene

Zinc finger protein 75D:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF75D

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF75D
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF75D Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b
SP1: - - -
SP2: - - - -
SP3: - -
SP4:
SP5:

Relevant External Links for ZNF75D Gene

GeneLoc Exon Structure for
ZNF75D
ECgene alternative splicing isoforms for
ZNF75D

Expression for ZNF75D Gene

mRNA expression in normal human tissues for ZNF75D Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF75D Gene

SOURCE GeneReport for Unigene cluster for ZNF75D Gene Hs.533540

genes like me logo Genes that share expressions with ZNF75D: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF75D Gene

Orthologs for ZNF75D Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF75D Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF75D 35
  • 99.74 (n)
  • 99.41 (a)
ZNF75D 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 62 (a)
OneToMany
-- 36
  • 57 (a)
OneToMany
ZNF75 36
  • 61 (a)
OneToMany
ZNF75D 35
  • 83.47 (n)
  • 70.95 (a)
ZNF75D 36
  • 69 (a)
OneToMany
dog
(Canis familiaris)
Mammalia ZNF75D 35
  • 87.1 (n)
  • 76.82 (a)
ZNF75D 36
  • 71 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 38 (a)
OneToMany
Species with no ortholog for ZNF75D:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF75D Gene

ENSEMBL:
Gene Tree for ZNF75D (if available)
TreeFam:
Gene Tree for ZNF75D (if available)

Paralogs for ZNF75D Gene

Paralogs for ZNF75D Gene

Pseudogenes.org Pseudogenes for ZNF75D Gene

genes like me logo Genes that share paralogs with ZNF75D: view

Variants for ZNF75D Gene

Sequence variations from dbSNP and Humsavar for ZNF75D Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs4589 -- 135,286,096(+) ACTTT(G/T)CTCTG utr-variant-3-prime, intron-variant
rs7042 -- 135,286,075(+) TCACT(C/G)TGAGC utr-variant-3-prime, intron-variant
rs14241 -- 135,286,291(+) TATGG(C/T)ACCAG utr-variant-3-prime, intron-variant
rs726546 -- 135,338,261(+) CAGAA(A/T)TGTCT intron-variant
rs884165 -- 135,324,813(-) TGTAC(C/T)GTATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF75D Gene

Variant ID Type Subtype PubMed ID
dgv2476e1 CNV Complex 17122850
nsv7104 CNV Loss 18451855
nsv469871 CNV Loss 16826518

Relevant External Links for ZNF75D Gene

HapMap Linkage Disequilibrium report
ZNF75D
Human Gene Mutation Database (HGMD)
ZNF75D
Locus Specific Mutation Databases (LSDB)
ZNF75D

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF75D Gene

Disorders for ZNF75D Gene

Relevant External Links for ZNF75D

Genetic Association Database (GAD)
ZNF75D
genes like me logo Genes that share disorders with ZNF75D: view

No data available for UniProtKB/Swiss-Prot for ZNF75D Gene

Publications for ZNF75D Gene

  1. Isolation of a zinc finger motif (ZNF75) mapping on chromosome Xq26. (PMID: 1505955) Villa A. … Vezzoni P. (Genomics 1992) 2 3 4
  2. ZNF75: isolation of a cDNA clone of the KRAB zinc finger gene subfamily mapped in YACs 1 Mb telomeric of HPRT. (PMID: 8288223) Villa A. … Vezzoni P. (Genomics 1993) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for ZNF75D Gene

Sources for ZNF75D Gene

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