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Aliases for ZNF75A Gene

Aliases for ZNF75A Gene

  • Zinc Finger Protein 75a 2 3

External Ids for ZNF75A Gene

Summaries for ZNF75A Gene

GeneCards Summary for ZNF75A Gene

ZNF75A (Zinc Finger Protein 75a) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF75D.

UniProtKB/Swiss-Prot for ZNF75A Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF75A Gene

Genomics for ZNF75A Gene

Genomic Location for ZNF75A Gene

Start:
3,305,406 bp from pter
End:
3,318,852 bp from pter
Size:
13,447 bases
Orientation:
Plus strand

Genomic View for ZNF75A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF75A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF75A Gene

Regulatory Elements for ZNF75A Gene

Proteins for ZNF75A Gene

  • Protein details for ZNF75A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96N20-ZN75A_HUMAN
    Recommended name:
    Zinc finger protein 75A
    Protein Accession:
    Q96N20
    Secondary Accessions:
    • Q0VDI8
    • Q92669

    Protein attributes for ZNF75A Gene

    Size:
    296 amino acids
    Molecular mass:
    34694 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF75A Gene

Proteomics data for ZNF75A Gene at MOPED

Post-translational modifications for ZNF75A Gene

No Post-translational modifications

Other Protein References for ZNF75A Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF75A Gene

Domains for ZNF75A Gene

Gene Families for ZNF75A Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

UniProtKB/Swiss-Prot:

ZN75A_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q96N20
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q96N20
Similarity:
  • Contains 5 C2H2-type zinc fingers.:
    • Q96N20
genes like me logo Genes that share domains with ZNF75A: view

Function for ZNF75A Gene

Molecular function for ZNF75A Gene

GENATLAS Biochemistry: zinc finger protein 75,related sequence A
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF75A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF75A: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF75A Gene

Localization for ZNF75A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF75A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF75A Gene COMPARTMENTS Subcellular localization image for ZNF75A gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF75A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF75A: view

Pathways for ZNF75A Gene

SuperPathways for ZNF75A Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF75A: view

Pathways by source for ZNF75A Gene

2 Reactome pathways for ZNF75A Gene

Interacting Proteins for ZNF75A Gene

Gene Ontology (GO) - Biological Process for ZNF75A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ZNF75A: view

Transcripts for ZNF75A Gene

Unigene Clusters for ZNF75A Gene

Zinc finger protein 75a:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF75A Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c
SP1: - - - - - - -
SP2: - - - - - - - - -
SP3: - - - - - -
SP4: - - -
SP5: - - -
SP6:
SP7:
SP8:
SP9: -

Relevant External Links for ZNF75A Gene

GeneLoc Exon Structure for
ZNF75A
ECgene alternative splicing isoforms for
ZNF75A

Expression for ZNF75A Gene

mRNA expression in normal human tissues for ZNF75A Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF75A Gene

SOURCE GeneReport for Unigene cluster for ZNF75A Gene Hs.513292

genes like me logo Genes that share expressions with ZNF75A: view

Orthologs for ZNF75A Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF75A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF75A 36
  • 99.21 (n)
  • 99.66 (a)
ZNF75A 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 53 (a)
OneToMany
ZNF75A 36
  • 88.36 (n)
  • 86.44 (a)
ZNF75A 37
  • 86 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 50 (a)
OneToMany
-- 37
  • 49 (a)
OneToMany
ZNF75A 36
  • 89.94 (n)
  • 88.47 (a)
oppossum
(Monodelphis domestica)
Mammalia ZNF75A 37
  • 34 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 4 (a)
OneToMany
Species with no ortholog for ZNF75A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF75A Gene

ENSEMBL:
Gene Tree for ZNF75A (if available)
TreeFam:
Gene Tree for ZNF75A (if available)

Paralogs for ZNF75A Gene

Paralogs for ZNF75A Gene

Selected SIMAP similar genes for ZNF75A Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF75A: view

Variants for ZNF75A Gene

Sequence variations from dbSNP and Humsavar for ZNF75A Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs37840 -- 3,312,953(+) GTTCT(G/T)TTAAT intron-variant
rs3840980 -- 3,312,915(-) AAAAA(-/A)GGAGA intron-variant
rs4786402 -- 3,314,860(+) AGACT(C/G)TCATT intron-variant
rs12325187 -- 3,314,997(+) TGTAG(C/G)GGAGG intron-variant
rs12325636 -- 3,314,867(+) CATTT(C/G)TCTAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF75A Gene

Variant ID Type Subtype PubMed ID
dgv2583n71 CNV Loss 21882294
nsv905212 CNV Gain 21882294

Relevant External Links for ZNF75A Gene

HapMap Linkage Disequilibrium report
ZNF75A

Disorders for ZNF75A Gene

Relevant External Links for ZNF75A

Genetic Association Database (GAD)
ZNF75A
genes like me logo Genes that share disorders with ZNF75A: view

No data available for UniProtKB/Swiss-Prot for ZNF75A Gene

Publications for ZNF75A Gene

  1. The ZNF75 zinc finger gene subfamily: isolation and mapping of the four members in humans and great apes. (PMID: 8661144) Villa A. … Vezzoni P. (Genomics 1996) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for ZNF75A Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF75A
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF75A
  • Block miRNA regulation of ZNF75A using miScript Target Protectors

Sources for ZNF75A Gene

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