External Ids for ZNF750 Gene
Previous GeneCards Identifiers for ZNF750 Gene
This gene encodes a protein with a nuclear localization site and a C2H2 zinc finger domain. Mutations in this gene have been associated with seborrhea-like dermatitis with psoriasiform elements. [provided by RefSeq, Jul 2008]
GeneCards Summary for ZNF750 Gene
ZNF750 (Zinc Finger Protein 750) is a Protein Coding gene. Diseases associated with ZNF750 include seborrhea-like dermatitis with psoriasiform elements and dermatitis. Among its related pathways are Gene Expression. GO annotations related to this gene include transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding and core promoter sequence-specific DNA binding. An important paralog of this gene is PRR35.
UniProtKB/Swiss-Prot for ZNF750 Gene
Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes. Specifically binds to the promoter of KLF4 and promotes its expression.