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Aliases for ZNF747 Gene

Aliases for ZNF747 Gene

  • Zinc Finger Protein 747 2 3 5

External Ids for ZNF747 Gene

Previous GeneCards Identifiers for ZNF747 Gene

  • GC16M030452
  • GC16M030453
  • GC16M030541
  • GC16M028106

Summaries for ZNF747 Gene

GeneCards Summary for ZNF747 Gene

ZNF747 (Zinc Finger Protein 747) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ENSG00000261459.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF747 Gene

Genomics for ZNF747 Gene

Regulatory Elements for ZNF747 Gene

Enhancers for ZNF747 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16F030566 1.5 FANTOM5 ENCODE 86.8 -34.5 -34528 6.0 PKNOX1 WRNIP1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF302 ENSG00000260267 NPIPB13 ZNF747 SMG1P2 ZNF764 ENSG00000260304 BCL7C ENSG00000261474 ZNF785 ENSG00000235560
GH16F030052 1.2 ENCODE 95.6 +481.1 481143 3.1 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 ZNF263 ZNF747 ZNF764 SMG1P2 NPIPB13 BCL7C ZNF785 PRR14 ZNF629 ZNF689 ENSG00000235560
GH16F031025 1.2 Ensembl ENCODE 74.9 -490.8 -490754 1.0 ZNF493 ZFP64 ARID4B DMAP1 ZNF48 SLC30A9 GLIS2 ZNF302 ZNF143 ZNF548 ENSG00000260267 ZNF747 ZNF720 NPIPB13 ZNF764 ENSG00000260304 BCL7C ZNF785 ENSG00000261474 KAT8
GH16F031252 1.6 FANTOM5 Ensembl ENCODE 46.4 -718.6 -718554 2.6 ATF1 PKNOX1 ARNT ZNF493 FOS ZNF202 JUNB NCOA1 REST ZNF623 ENSG00000260267 ZNF720 ZNF747 ZNF764 ENSG00000260304 NPIPB13 PYDC1 BCL7C ZNF785 ENSG00000261474
GH16F030334 1.1 ENCODE 65.1 +200.0 199986 2.6 PKNOX1 ZFP64 ARID4B SIN3A DMAP1 YY1 KLF13 ZNF263 SP3 SP5 ZNF747 NPIPB13 ZNF764 SMG1P2 ZNF785 ENSG00000260304 BCL7C ZNF629 ZNF689 SMG1P5
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF747 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF747 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000271931 547 2801 HDGF PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9

Genomic Location for ZNF747 Gene

30,530,367 bp from pter
30,535,347 bp from pter
4,981 bases
Minus strand

Genomic View for ZNF747 Gene

Genes around ZNF747 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF747 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF747 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF747 Gene

Proteins for ZNF747 Gene

  • Protein details for ZNF747 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    KRAB domain-containing protein ZNF747
    Protein Accession:
    Secondary Accessions:
    • A8K827
    • B7WNU3
    • Q59FB4
    • Q96NW0

    Protein attributes for ZNF747 Gene

    191 amino acids
    Molecular mass:
    20610 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB70760.1; Type=Erroneous termination; Positions=172; Note=Translated as Lys.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF747 Gene


neXtProt entry for ZNF747 Gene

Post-translational modifications for ZNF747 Gene

No Post-translational modifications

Other Protein References for ZNF747 Gene

No data available for DME Specific Peptides for ZNF747 Gene

Domains & Families for ZNF747 Gene

Gene Families for ZNF747 Gene

Protein Domains for ZNF747 Gene


Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Contains 1 KRAB domain.
genes like me logo Genes that share domains with ZNF747: view

Function for ZNF747 Gene

Gene Ontology (GO) - Molecular Function for ZNF747 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF747: view
genes like me logo Genes that share phenotypes with ZNF747: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF747 Gene

Localization for ZNF747 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF747 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF747 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with ZNF747: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ZNF747 Gene

Pathways & Interactions for ZNF747 Gene

SuperPathways for ZNF747 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF747: view

Pathways by source for ZNF747 Gene

2 Reactome pathways for ZNF747 Gene

Gene Ontology (GO) - Biological Process for ZNF747 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF747: view

No data available for SIGNOR curated interactions for ZNF747 Gene

Transcripts for ZNF747 Gene

Unigene Clusters for ZNF747 Gene

Zinc finger protein 747:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF747 Gene

No ASD Table

Relevant External Links for ZNF747 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF747 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF747 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF747 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF747 Gene

Protein tissue co-expression partners for ZNF747 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF747 Gene:


SOURCE GeneReport for Unigene cluster for ZNF747 Gene:

genes like me logo Genes that share expression patterns with ZNF747: view

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF747 Gene

Orthologs for ZNF747 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF747 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia ZNF747 34
  • 79.89 (n)
(Monodelphis domestica)
Mammalia -- 35
  • 14 (a)
(Mus musculus)
Mammalia E430018J23Rik 35
  • 13 (a)
Zfp764 35
  • 13 (a)
Zfp747 35
  • 12 (a)
9130019O22Rik 35
  • 10 (a)
Species where no ortholog for ZNF747 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF747 Gene

Gene Tree for ZNF747 (if available)
Gene Tree for ZNF747 (if available)

Paralogs for ZNF747 Gene

genes like me logo Genes that share paralogs with ZNF747: view

Variants for ZNF747 Gene

Sequence variations from dbSNP and Humsavar for ZNF747 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs111235386 -- 30,536,501(+) CCCCA(C/G)GACTC nc-transcript-variant, upstream-variant-2KB
rs112801328 -- 30,534,223(+) ACTTC(A/G)CCACC upstream-variant-2KB, reference, missense, stop-gained
rs1137888 -- 30,531,385(-) aagat(C/T)taaag intron-variant, utr-variant-3-prime
rs113843360 -- 30,533,770(+) AAAAA(A/C)CAGCC intron-variant, upstream-variant-2KB
rs113879931 -- 30,532,616(+) CGCCC(C/T)TCGCC upstream-variant-2KB, reference, synonymous-codon, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF747 Gene

Variant ID Type Subtype PubMed ID
nsv1784 CNV insertion 18451855

Variation tolerance for ZNF747 Gene

Residual Variation Intolerance Score: 91.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.57; 44.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF747 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF747 Gene

Disorders for ZNF747 Gene

Relevant External Links for ZNF747

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF747 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF747 Gene

Publications for ZNF747 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PMID: 10493829) Loftus B.J. … Adams M.D. (Genomics 1999) 2 3 64
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  4. PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion. (PMID: 26598620) Dart A.E. … Wells C.M. (J. Cell Biol. 2015) 3 64
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64

Products for ZNF747 Gene

Sources for ZNF747 Gene

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