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Aliases for ZNF738 Gene

Aliases for ZNF738 Gene

  • Zinc Finger Protein 738 2 3 5

External Ids for ZNF738 Gene

Previous GeneCards Identifiers for ZNF738 Gene

  • GC19P021541
  • GC19P021032

Summaries for ZNF738 Gene

GeneCards Summary for ZNF738 Gene

ZNF738 (Zinc Finger Protein 738) is a Pseudogene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and ubiquitin-protein transferase activity. An important paralog of this gene is ENSG00000269237.

UniProtKB/Swiss-Prot for ZNF738 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF738 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF738 Gene

Genomics for ZNF738 Gene

Regulatory Elements for ZNF738 Gene

Enhancers for ZNF738 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H021358 0.8 ENCODE 20.7 +0.3 264 1 TBP PKNOX1 SIN3A ZBTB40 RFX5 ZNF350 ZNF143 FOS SMAD5 NFYA LOC105372321 ZNF708 ZNF100 ZNF738 LOC641367 ZNF43 ZNF66 LOC100422298
GH19H021438 0.5 ENCODE 16 +80.8 80750 2 ZNF217 SMARCE1 CTBP1 GATA3 CEBPA ZNF738 LOC105372321 GC19P021412
GH19H021256 0.6 ENCODE 12.9 -102.0 -102017 0 CTCF TEAD1 TEAD2 REST RAD21 TEAD3 ZNF738 ENSG00000269839 ENSG00000268747
GH19H021019 1.3 Ensembl ENCODE 4.4 -336.7 -336654 4 HDGF PKNOX1 ATF1 ARID4B SIN3A DMAP1 YY1 ZNF207 ATF7 FOS ZNF100 LOC641367 ZNF714 ZNF90 BNIP3P26 RPL7AP10 ZNF66 ZNF431 ZNF486 BNIP3P16
GH19H021141 1 ENCODE 5.6 -216.0 -215977 3 HDGF PKNOX1 ATF1 ARID4B SIN3A DMAP1 YY1 TCF12 ELK1 ATF7 ZNF100 ZNF708 ZNF714 LOC641367 ENSG00000268555 LOC105372321 ZNF738 ZNF429 ZNF431 RPL7AP10
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF738 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF738 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000108342 571 1800 TBP PKNOX1 SIN3A ZBTB40 RFX5 ZNF350 ZNF143 FOS IKZF2 NFYA

Transcription factor binding sites by QIAGEN in the ZNF738 gene promoter:

Genomic Location for ZNF738 Gene

Chromosome:
19
Start:
21,358,930 bp from pter
End:
21,388,582 bp from pter
Size:
29,653 bases
Orientation:
Plus strand

Genomic View for ZNF738 Gene

Genes around ZNF738 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF738 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF738 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF738 Gene

Proteins for ZNF738 Gene

  • Protein details for ZNF738 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NE65-ZN738_HUMAN
    Recommended name:
    Protein ZNF738
    Protein Accession:
    Q8NE65
    Secondary Accessions:
    • A8K4N7

    Protein attributes for ZNF738 Gene

    Size:
    137 amino acids
    Molecular mass:
    15884 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF738 Gene

Post-translational modifications for ZNF738 Gene

  • Ubiquitination at isoforms=12 and Lys32
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF738 Gene

No data available for DME Specific Peptides for ZNF738 Gene

Domains & Families for ZNF738 Gene

Gene Families for ZNF738 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ZNF738 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF738 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ZNF738: view

No data available for UniProtKB/Swiss-Prot for ZNF738 Gene

Function for ZNF738 Gene

Molecular function for ZNF738 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF738 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0004842 ubiquitin-protein transferase activity ISS --
genes like me logo Genes that share ontologies with ZNF738: view
genes like me logo Genes that share phenotypes with ZNF738: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ZNF738
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF738 Gene

Localization for ZNF738 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF738 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF738 gene
Compartment Confidence
nucleus 4
cytosol 2
extracellular 1
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for ZNF738 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF738: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF738 Gene

Pathways & Interactions for ZNF738 Gene

SuperPathways for ZNF738 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF738: view

Pathways by source for ZNF738 Gene

2 Reactome pathways for ZNF738 Gene

Interacting Proteins for ZNF738 Gene

Gene Ontology (GO) - Biological Process for ZNF738 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000209 protein polyubiquitination ISS --
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF738: view

No data available for SIGNOR curated interactions for ZNF738 Gene

Drugs & Compounds for ZNF738 Gene

No Compound Related Data Available

Transcripts for ZNF738 Gene

mRNA/cDNA for ZNF738 Gene

(6) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF738 Gene

Zinc finger protein 738:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for ZNF738
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF738 Gene

No ASD Table

Relevant External Links for ZNF738 Gene

GeneLoc Exon Structure for
ZNF738
ECgene alternative splicing isoforms for
ZNF738

Expression for ZNF738 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF738 Gene

Protein differential expression in normal tissues from HIPED for ZNF738 Gene

This gene is overexpressed in Serum (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF738 Gene



Protein tissue co-expression partners for ZNF738 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF738 Gene:

ZNF738

SOURCE GeneReport for Unigene cluster for ZNF738 Gene:

Hs.124384
genes like me logo Genes that share expression patterns with ZNF738: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF738 Gene

Orthologs for ZNF738 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF738 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF738 34
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 34
  • 53 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Gm26965 34
  • 47 (a)
ManyToMany
RP24-242F4.8 34
  • 40 (a)
ManyToMany
Gm10037 34
  • 39 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 34
  • 39 (a)
ManyToMany
-- 34
  • 34 (a)
ManyToMany
-- 34
  • 32 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 23 (a)
OneToMany
Species where no ortholog for ZNF738 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF738 Gene

ENSEMBL:
Gene Tree for ZNF738 (if available)
TreeFam:
Gene Tree for ZNF738 (if available)

Paralogs for ZNF738 Gene

Paralogs for ZNF738 Gene

(406) SIMAP similar genes for ZNF738 Gene using alignment to 5 proteins:

Pseudogenes.org Pseudogenes for ZNF738 Gene

genes like me logo Genes that share paralogs with ZNF738: view

Variants for ZNF738 Gene

Sequence variations from dbSNP and Humsavar for ZNF738 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000077288 -- 21,356,954(+) GAAGC(-/AGA)AGATC upstream-variant-2KB
rs1000096284 -- 21,388,998(+) GCCAA(C/T)ATGGT downstream-variant-500B
rs1000127592 -- 21,379,368(+) ATTGT(C/T)TGGGT nc-transcript-variant
rs1000310246 -- 21,373,045(+) TGAGC(A/C)CAAGG intron-variant
rs1000450139 -- 21,380,919(+) CTGTT(C/G)AGGAA nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF738 Gene

Variant ID Type Subtype PubMed ID
esv2663001 CNV deletion 23128226
esv2665276 CNV deletion 23128226
esv2718325 CNV deletion 23290073
esv2718330 CNV deletion 23290073
esv2718331 CNV deletion 23290073
esv2718332 CNV deletion 23290073
esv2718333 CNV deletion 23290073
esv2751783 CNV loss 17911159
esv4924 OTHER complex 18987735
nsv1061327 CNV gain 25217958
nsv1138683 CNV deletion 24896259
nsv1138684 CNV deletion 24896259
nsv1140249 OTHER inversion 24896259
nsv1151573 OTHER inversion 26484159
nsv458377 CNV gain 19166990
nsv578809 CNV gain 21841781
nsv578952 CNV gain 21841781
nsv963023 CNV duplication 23825009

Variation tolerance for ZNF738 Gene

Gene Damage Index Score: 1.16; 23.52% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF738 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF738

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF738 Gene

Disorders for ZNF738 Gene

Relevant External Links for ZNF738

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF738

No disorders were found for ZNF738 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF738 Gene

Publications for ZNF738 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 60
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for ZNF738 Gene

Sources for ZNF738 Gene

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