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Aliases for ZNF737 Gene

Aliases for ZNF737 Gene

  • Zinc Finger Protein 737 2 3 5
  • ZNF102 3 4
  • Zinc Finger Protein 102 (Y3) 3
  • Zinc Finger Protein 102 4

External Ids for ZNF737 Gene

Previous GeneCards Identifiers for ZNF737 Gene

  • GC19U900745
  • GC19M020524
  • GC19M020720
  • GC19M020211
  • GC19M020804
  • GC19M020957
  • GC19M020614
  • GC19M021059
  • GC19M021115
  • GC19M021342
  • GC19M021518
  • GC19M021706
  • GC19M021901

Summaries for ZNF737 Gene

GeneCards Summary for ZNF737 Gene

ZNF737 (Zinc Finger Protein 737) is a Protein Coding gene. Among its related pathways are Gene Expression. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF66.

UniProtKB/Swiss-Prot for ZNF737 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF737 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF737 Gene

Genomics for ZNF737 Gene

GeneHancer (GH) Regulatory Elements for ZNF737 Gene

Promoters and enhancers for ZNF737 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I020564 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE 558.5 +0.3 332 2.2 ELF3 PKNOX1 ARID4B SIN3A DMAP1 ZNF48 RAD21 ELK1 FOS IKZF2 ZNF737 ZNF626 GC19M022326 GC19M022336 LOC105372316 ENSG00000269110
GH19I020367 Enhancer 0.8 FANTOM5 ENCODE 1.3 +197.6 197635 0.8 CTCF MXI1 RFX1 POLR2A BACH1 SIN3A ZNF682 ZNF737 PIR36651 LOC105372315 BNIP3P21 ZNF826P
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF737 on UCSC Golden Path with GeneCards custom track

Genomic Locations for ZNF737 Gene

Genomic Locations for ZNF737 Gene
chr19:20,531,224-20,565,847
(GRCh38/hg38)
Size:
34,624 bases
Orientation:
Minus strand
chr19:20,718,631-20,748,626
(GRCh37/hg19)

Genomic View for ZNF737 Gene

Genes around ZNF737 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF737 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF737 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF737 Gene

Proteins for ZNF737 Gene

  • Protein details for ZNF737 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O75373-ZN737_HUMAN
    Recommended name:
    Zinc finger protein 737
    Protein Accession:
    O75373
    Secondary Accessions:
    • C9JHM3

    Protein attributes for ZNF737 Gene

    Size:
    536 amino acids
    Molecular mass:
    61931 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF737 Gene

Post-translational modifications for ZNF737 Gene

No Post-translational modifications

No data available for DME Specific Peptides for ZNF737 Gene

Domains & Families for ZNF737 Gene

Gene Families for ZNF737 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF737 Gene

Suggested Antigen Peptide Sequences for ZNF737 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O75373

UniProtKB/Swiss-Prot:

ZN737_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF737: view

Function for ZNF737 Gene

Molecular function for ZNF737 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF737 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF737: view
genes like me logo Genes that share phenotypes with ZNF737: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF737 Gene

Localization for ZNF737 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF737 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF737 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF737 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF737: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF737 Gene

Pathways & Interactions for ZNF737 Gene

SuperPathways for ZNF737 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF737: view

Pathways by source for ZNF737 Gene

2 Reactome pathways for ZNF737 Gene

Interacting Proteins for ZNF737 Gene

Gene Ontology (GO) - Biological Process for ZNF737 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF737: view

No data available for SIGNOR curated interactions for ZNF737 Gene

Drugs & Compounds for ZNF737 Gene

No Compound Related Data Available

Transcripts for ZNF737 Gene

mRNA/cDNA for ZNF737 Gene

(7) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF737 Gene

Zinc finger protein 737:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF737 Gene

No ASD Table

Relevant External Links for ZNF737 Gene

GeneLoc Exon Structure for
ZNF737
ECgene alternative splicing isoforms for
ZNF737

Expression for ZNF737 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF737 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF737 Gene:

ZNF737

SOURCE GeneReport for Unigene cluster for ZNF737 Gene:

Hs.515696
genes like me logo Genes that share expression patterns with ZNF737: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF737 Gene

Orthologs for ZNF737 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF737 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF737 33 34
  • 99.69 (n)
cow
(Bos Taurus)
Mammalia -- 34
  • 56 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 51 (a)
ManyToMany
-- 34
  • 40 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 34
  • 40 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp386 34
  • 37 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 54 (a)
ManyToMany
-- 34
  • 42 (a)
ManyToMany
-- 34
  • 40 (a)
ManyToMany
-- 34
  • 35 (a)
ManyToMany
-- 34
  • 32 (a)
ManyToMany
-- 34
  • 32 (a)
ManyToMany
-- 34
  • 32 (a)
ManyToMany
-- 34
  • 30 (a)
ManyToMany
Species where no ortholog for ZNF737 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF737 Gene

ENSEMBL:
Gene Tree for ZNF737 (if available)
TreeFam:
Gene Tree for ZNF737 (if available)

Paralogs for ZNF737 Gene

(622) SIMAP similar genes for ZNF737 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF737: view

Variants for ZNF737 Gene

Sequence variations from dbSNP and Humsavar for ZNF737 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000152511 -- 20,553,270(-) T/C intron_variant
rs1000359452 -- 20,546,944(-) T/C intron_variant
rs1000684851 -- 20,543,066(-) C/A 3_prime_UTR_variant, intron_variant
rs1000904893 -- 20,537,171(-) T/C genic_downstream_transcript_variant, intron_variant
rs1000966429 -- 20,548,325(-) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF737 Gene

Variant ID Type Subtype PubMed ID
dgv1027e212 CNV loss 25503493
dgv17n14 CNV loss 18776910
dgv33e213 CNV loss 24956385
dgv3457n100 CNV gain 25217958
dgv3460n100 CNV loss 25217958
dgv3461n100 CNV loss 25217958
dgv3464n100 CNV loss 25217958
dgv3465n100 CNV loss 25217958
dgv399n27 CNV loss 19166990
dgv401n27 CNV loss 19166990
dgv402n27 CNV loss 19166990
dgv403n27 CNV loss 19166990
dgv509e201 CNV deletion 23290073
dgv6303n54 CNV loss 21841781
dgv6304n54 CNV loss 21841781
dgv6305n54 CNV gain 21841781
dgv6307n54 CNV loss 21841781
dgv630e199 CNV deletion 23128226
dgv6310n54 CNV loss 21841781
dgv6314n54 CNV loss 21841781
dgv69e203 CNV loss 21179565
esv1696645 CNV insertion 17803354
esv2422114 CNV deletion 20811451
esv2658579 CNV deletion 23128226
esv2718311 CNV deletion 23290073
esv2718314 CNV deletion 23290073
esv2718315 CNV deletion 23290073
esv2751781 CNV gain 17911159
esv2758749 CNV loss 17122850
esv3643886 CNV loss 21293372
esv3643888 CNV loss 21293372
esv3643889 CNV loss 21293372
esv3893172 CNV gain+loss 25118596
esv3893176 CNV gain 25118596
nsv1061245 CNV loss 25217958
nsv1125670 CNV tandem duplication 24896259
nsv1141886 OTHER inversion 24896259
nsv1160595 CNV deletion 26073780
nsv2437 CNV deletion 18451855
nsv442762 CNV loss 18776908
nsv458377 CNV gain 19166990
nsv458509 CNV loss 19166990
nsv514893 CNV loss 21397061
nsv517263 CNV gain+loss 19592680
nsv523471 CNV loss 19592680
nsv523499 CNV gain 19592680
nsv578809 CNV gain 21841781
nsv578810 CNV loss 21841781
nsv578909 CNV loss 21841781
nsv578910 CNV gain 21841781
nsv578911 CNV loss 21841781
nsv578912 CNV gain 21841781
nsv578913 CNV loss 21841781
nsv578914 CNV loss 21841781
nsv960807 CNV duplication 23825009

Variation tolerance for ZNF737 Gene

Residual Variation Intolerance Score: 98.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.19; 84.83% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF737 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF737

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF737 Gene

Disorders for ZNF737 Gene

Additional Disease Information for ZNF737

No disorders were found for ZNF737 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF737 Gene

Publications for ZNF737 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  2. Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. (PMID: 8467795) Bellefroid EJ … Szpirer C (The EMBO journal 1993) 3 4 58
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for ZNF737 Gene

Sources for ZNF737 Gene

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