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Aliases for ZNF737 Gene

Aliases for ZNF737 Gene

  • Zinc Finger Protein 737 2 3 5
  • ZNF102 3 4
  • Zinc Finger Protein 102 (Y3) 3
  • Zinc Finger Protein 102 4

External Ids for ZNF737 Gene

Previous GeneCards Identifiers for ZNF737 Gene

  • GC19U900745
  • GC19M020524
  • GC19M020720
  • GC19M020211
  • GC19M020804
  • GC19M020957
  • GC19M020614
  • GC19M021059
  • GC19M021115
  • GC19M021342

Summaries for ZNF737 Gene

GeneCards Summary for ZNF737 Gene

ZNF737 (Zinc Finger Protein 737) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF93.

UniProtKB/Swiss-Prot for ZNF737 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF737 Gene

Genomics for ZNF737 Gene

Regulatory Elements for ZNF737 Gene

Enhancers for ZNF737 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F020564 0.2 ENCODE 8.5 +0.3 309 2.2 ELF3 TBP PKNOX1 ARID4B SIN3A DMAP1 ZNF48 RAD21 ZBTB40 ELK1 ZNF737 ZNF626 GC19M021748
GH19F020473 0.2 Ensembl 7.9 +92.3 92347 0.2 ZNF737 LOC105372316 PIR44085
GH19F020466 1 Ensembl ENCODE 5.8 +99.2 99153 0.7 ZNF737 ZNF626 LOC105372316 BNIP3P23
GH19F020367 1 FANTOM5 ENCODE 1.3 +197.6 197636 0.8 CTCF RFX1 SMARCA4 POLR2A MAFK ZNF682 ZNF737 PIR36651 BNIP3P21
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ZNF737 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF737 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000344993 546 1799 ELF3 TBP PKNOX1 ARID4B SIN3A DMAP1 ZNF48 RAD21 ZBTB40 CBX5

Genomic Location for ZNF737 Gene

Chromosome:
19
Start:
20,531,224 bp from pter
End:
20,565,847 bp from pter
Size:
34,624 bases
Orientation:
Minus strand

Genomic View for ZNF737 Gene

Genes around ZNF737 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF737 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF737 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF737 Gene

Proteins for ZNF737 Gene

  • Protein details for ZNF737 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O75373-ZN737_HUMAN
    Recommended name:
    Zinc finger protein 737
    Protein Accession:
    O75373
    Secondary Accessions:
    • C9JHM3

    Protein attributes for ZNF737 Gene

    Size:
    536 amino acids
    Molecular mass:
    61931 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF737 Gene

Post-translational modifications for ZNF737 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF737 Gene

Domains & Families for ZNF737 Gene

Gene Families for ZNF737 Gene

Protein Domains for ZNF737 Gene

Suggested Antigen Peptide Sequences for ZNF737 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O75373

UniProtKB/Swiss-Prot:

ZN737_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 13 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF737: view

Function for ZNF737 Gene

Molecular function for ZNF737 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF737 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding IBA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF737: view
genes like me logo Genes that share phenotypes with ZNF737: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF737 Gene

Localization for ZNF737 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF737 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF737 Gene COMPARTMENTS Subcellular localization image for ZNF737 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF737 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZNF737: view

Pathways & Interactions for ZNF737 Gene

SuperPathways for ZNF737 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF737: view

Pathways by source for ZNF737 Gene

2 Reactome pathways for ZNF737 Gene

Interacting Proteins for ZNF737 Gene

Gene Ontology (GO) - Biological Process for ZNF737 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
genes like me logo Genes that share ontologies with ZNF737: view

No data available for SIGNOR curated interactions for ZNF737 Gene

Transcripts for ZNF737 Gene

mRNA/cDNA for ZNF737 Gene

(7) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF737 Gene

Zinc finger protein 737:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF737 Gene

No ASD Table

Relevant External Links for ZNF737 Gene

GeneLoc Exon Structure for
ZNF737
ECgene alternative splicing isoforms for
ZNF737

Expression for ZNF737 Gene

mRNA expression in normal human tissues for ZNF737 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF737 Gene:

ZNF737

SOURCE GeneReport for Unigene cluster for ZNF737 Gene:

Hs.515696
genes like me logo Genes that share expression patterns with ZNF737: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZNF737 Gene

Orthologs for ZNF737 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF737 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF737 34 35
  • 99.69 (n)
cow
(Bos Taurus)
Mammalia -- 35
  • 56 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 51 (a)
ManyToMany
-- 35
  • 40 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 40 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp386 35
  • 37 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 54 (a)
ManyToMany
-- 35
  • 42 (a)
ManyToMany
-- 35
  • 40 (a)
ManyToMany
-- 35
  • 35 (a)
ManyToMany
-- 35
  • 32 (a)
ManyToMany
-- 35
  • 32 (a)
ManyToMany
-- 35
  • 32 (a)
ManyToMany
-- 35
  • 30 (a)
ManyToMany
Species where no ortholog for ZNF737 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF737 Gene

ENSEMBL:
Gene Tree for ZNF737 (if available)
TreeFam:
Gene Tree for ZNF737 (if available)

Paralogs for ZNF737 Gene

(622) SIMAP similar genes for ZNF737 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF737: view

Variants for ZNF737 Gene

Sequence variations from dbSNP and Humsavar for ZNF737 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10410201 -- 20,544,729(+) GGAGC(A/G)CTTAA intron-variant, nc-transcript-variant, reference, missense
rs10410284 -- 20,543,027(+) TATAT(A/T)CAATG intron-variant, utr-variant-3-prime
rs10410997 -- 20,552,332(+) AAAAA(A/G)AAAAA intron-variant
rs10411329 -- 20,544,657(+) GCCTT(C/T)GCCAC intron-variant, nc-transcript-variant, reference, missense
rs10411665 -- 20,536,380(+) GCtaa(C/T)tttta intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF737 Gene

Variant ID Type Subtype PubMed ID
dgv1027e212 CNV loss 25503493
dgv17n14 CNV loss 18776910
dgv33e213 CNV loss 24956385
dgv3457n100 CNV gain 25217958
dgv3460n100 CNV loss 25217958
dgv3461n100 CNV loss 25217958
dgv3464n100 CNV loss 25217958
dgv3465n100 CNV loss 25217958
dgv399n27 CNV loss 19166990
dgv401n27 CNV loss 19166990
dgv402n27 CNV loss 19166990
dgv403n27 CNV loss 19166990
dgv509e201 CNV deletion 23290073
dgv6303n54 CNV loss 21841781
dgv6304n54 CNV loss 21841781
dgv6305n54 CNV gain 21841781
dgv6307n54 CNV loss 21841781
dgv630e199 CNV deletion 23128226
dgv6310n54 CNV loss 21841781
dgv6314n54 CNV loss 21841781
dgv69e203 CNV loss 21179565
esv1696645 CNV insertion 17803354
esv2422114 CNV deletion 20811451
esv2658579 CNV deletion 23128226
esv2718311 CNV deletion 23290073
esv2718314 CNV deletion 23290073
esv2718315 CNV deletion 23290073
esv2751781 CNV gain 17911159
esv2758749 CNV loss 17122850
esv3643886 CNV loss 21293372
esv3643888 CNV loss 21293372
esv3643889 CNV loss 21293372
esv3893172 CNV gain+loss 25118596
esv3893176 CNV gain 25118596
nsv1061245 CNV loss 25217958
nsv1125670 CNV tandem duplication 24896259
nsv1141886 OTHER inversion 24896259
nsv1160595 CNV deletion 26073780
nsv2437 CNV deletion 18451855
nsv442762 CNV loss 18776908
nsv458377 CNV gain 19166990
nsv458509 CNV loss 19166990
nsv514893 CNV loss 21397061
nsv517263 CNV gain+loss 19592680
nsv523471 CNV loss 19592680
nsv523499 CNV gain 19592680
nsv578809 CNV gain 21841781
nsv578810 CNV loss 21841781
nsv578909 CNV loss 21841781
nsv578910 CNV gain 21841781
nsv578911 CNV loss 21841781
nsv578912 CNV gain 21841781
nsv578913 CNV loss 21841781
nsv578914 CNV loss 21841781
nsv960807 CNV duplication 23825009

Variation tolerance for ZNF737 Gene

Residual Variation Intolerance Score: 98.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.19; 84.83% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF737 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF737

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF737 Gene

Disorders for ZNF737 Gene

Relevant External Links for ZNF737

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF737

No disorders were found for ZNF737 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF737 Gene

Publications for ZNF737 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  2. Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells. (PMID: 8467795) Bellefroid E.J. … Martial J.A. (EMBO J. 1993) 3 4 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ZNF737 Gene

Sources for ZNF737 Gene

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