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Aliases for ZNF736 Gene

Aliases for ZNF736 Gene

  • Zinc Finger Protein 736 2 3

External Ids for ZNF736 Gene

Previous GeneCards Identifiers for ZNF736 Gene

  • GC00U922630
  • GC07P063767
  • GC07P060153

Summaries for ZNF736 Gene

GeneCards Summary for ZNF736 Gene

ZNF736 (Zinc Finger Protein 736) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF253.

UniProtKB/Swiss-Prot for ZNF736 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF736 Gene

Genomics for ZNF736 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF736 Gene

Chromosome:
7
Start:
64,307,459 bp from pter
End:
64,356,634 bp from pter
Size:
49,176 bases
Orientation:
Plus strand

Genomic View for ZNF736 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for ZNF736 Gene

No data available for Regulatory Elements for ZNF736 Gene

Proteins for ZNF736 Gene

  • Protein details for ZNF736 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B4DX44-ZN736_HUMAN
    Recommended name:
    Zinc finger protein 736
    Protein Accession:
    B4DX44

    Protein attributes for ZNF736 Gene

    Size:
    427 amino acids
    Molecular mass:
    49868 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF736 Gene

Proteomics data for ZNF736 Gene at MOPED

Post-translational modifications for ZNF736 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF736 Gene

No data available for DME Specific Peptides for ZNF736 Gene

Domains & Families for ZNF736 Gene

Gene Families for ZNF736 Gene

Protein Domains for ZNF736 Gene

Suggested Antigen Peptide Sequences for ZNF736 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

B4DX44

UniProtKB/Swiss-Prot:

ZN736_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 10 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 10 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF736: view

Function for ZNF736 Gene

Molecular function for ZNF736 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF736 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding IBA --
GO:0003676 nucleic acid binding --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF736: view

Phenotypes for ZNF736 Gene

GenomeRNAi human phenotypes for ZNF736:
genes like me logo Genes that share phenotypes with ZNF736: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF736 Gene

Localization for ZNF736 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF736 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF736 Gene COMPARTMENTS Subcellular localization image for ZNF736 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF736 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZNF736: view

Pathways & Interactions for ZNF736 Gene

SuperPathways for ZNF736 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF736: view

Pathways by source for ZNF736 Gene

2 Reactome pathways for ZNF736 Gene

Interacting Proteins for ZNF736 Gene

Gene Ontology (GO) - Biological Process for ZNF736 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF736: view

No data available for SIGNOR curated interactions for ZNF736 Gene

Drugs & Compounds for ZNF736 Gene

No Compound Related Data Available

Transcripts for ZNF736 Gene

mRNA/cDNA for ZNF736 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(8) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF736 Gene

Zinc finger protein 736:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF736 Gene

No ASD Table

Relevant External Links for ZNF736 Gene

GeneLoc Exon Structure for
ZNF736
ECgene alternative splicing isoforms for
ZNF736

Expression for ZNF736 Gene

mRNA expression in normal human tissues for ZNF736 Gene

SOURCE GeneReport for Unigene cluster for ZNF736 Gene Hs.734771

genes like me logo Genes that share expression patterns with ZNF736: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF736 Gene

Orthologs for ZNF736 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF736 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF736 35
  • 99.06 (n)
  • 98.83 (a)
ZNF736 36
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp87 16
Zfp85-rs1 36
  • 43 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 36
  • 39 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 29 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 28 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 40 (a)
ManyToMany
-- 36
  • 26 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 23 (a)
ManyToMany
-- 36
  • 24 (a)
ManyToMany
-- 36
  • 23 (a)
ManyToMany
-- 36
  • 23 (a)
ManyToMany
Species with no ortholog for ZNF736:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF736 Gene

ENSEMBL:
Gene Tree for ZNF736 (if available)
TreeFam:
Gene Tree for ZNF736 (if available)

Paralogs for ZNF736 Gene

(487) SIMAP similar genes for ZNF736 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF736: view

Variants for ZNF736 Gene

Sequence variations from dbSNP and Humsavar for ZNF736 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs581612 -- 64,346,441(-) gtatc(C/T)tccaa intron-variant
rs583281 -- 64,320,685(+) AGGCA(G/T)TTTGA intron-variant
rs587711 -- 64,354,109(+) TGTTT(A/T)CTTGT utr-variant-3-prime
rs590890 -- 64,312,752(-) CAGGT(A/C)CCTGT upstream-variant-2KB
rs592136 -- 64,333,281(-) tttct(C/T)agagc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF736 Gene

Variant ID Type Subtype PubMed ID
nsv888255 CNV Loss 21882294
dgv1147e201 CNV Deletion 23290073
nsv888259 CNV Gain 21882294
dgv1212e199 CNV Deletion 23128226
nsv888264 CNV Gain 21882294
nsv522412 CNV Loss 19592680
dgv7306n71 CNV Gain 21882294
esv2422405 CNV Duplication 17116639
nsv464515 CNV Loss 19166990
nsv888269 CNV Gain 21882294
esv2734575 CNV Deletion 23290073
nsv888270 CNV Gain 21882294
nsv518721 CNV Loss 19592680

Variation tolerance for ZNF736 Gene

Gene Damage Index Score: 11.33; 92.64% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF736 Gene

HapMap Linkage Disequilibrium report
ZNF736

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF736 Gene

Disorders for ZNF736 Gene

Relevant External Links for ZNF736

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF736
genes like me logo Genes that share disorders with ZNF736: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF736 Gene

Publications for ZNF736 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  3. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 67
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for ZNF736 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF736
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF736
  • Block miRNA regulation of ZNF736 using miScript Target Protectors

Sources for ZNF736 Gene

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