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Aliases for ZNF736 Gene

Aliases for ZNF736 Gene

  • Zinc Finger Protein 736 2 3 5

External Ids for ZNF736 Gene

Previous GeneCards Identifiers for ZNF736 Gene

  • GC00U922630
  • GC07P063767
  • GC07P060153

Summaries for ZNF736 Gene

GeneCards Summary for ZNF736 Gene

ZNF736 (Zinc Finger Protein 736) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF727.

UniProtKB/Swiss-Prot for ZNF736 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF736 Gene

Genomics for ZNF736 Gene

Regulatory Elements for ZNF736 Gene

Enhancers for ZNF736 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F064312 0.9 ENCODE 12.4 +6.5 6494 3.0 TBP HDAC1 PKNOX1 WRNIP1 NFRKB SIN3A ZBTB40 RFX5 YY1 ZNF121 ZNF736 YWHAEP1 GUSBP6 SEPHS1P1 GC07M064314 LOC105375322
GH07F064574 0.7 Ensembl ENCODE 9.2 +267.3 267283 1.3 POLR2A NFYB SIN3A ZNF107 ZNF736 ZNF680P1 ZNF138 LOC100128885 LOC641746
GH07F064581 0.6 ENCODE 9.4 +274.8 274845 0.7 ARID1B NCOR1 GATA2 TAL1 IKZF1 TRIM24 HES1 ZNF736 LOC641746 LOC100128885
GH07F064849 1 Ensembl ENCODE 4 +542.4 542353 1.3 CTCF KLF1 CBX3 NFRKB ZNF316 GATA3 POLR2A NFE2 FOS TRIM24 EEF1DP4 LOC441239 ZNF117 ZNF736 SEPHS1P1 PIR62935
GH07F064305 1.2 FANTOM5 ENCODE 0.8 -0.2 -229 2.6 HDGF ATF1 CREB3L1 ZNF2 ETS1 YY1 ZNF143 ZNF263 SP3 REST GUSBP6 ZNF680 YWHAEP1 ZNF680P1 TRIM60P18 SEPHS1P1 CCT6P3 ZNF107 ZNF736 LOC105375323
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF736 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF736 Gene

Chromosome:
7
Start:
64,307,459 bp from pter
End:
64,356,634 bp from pter
Size:
49,176 bases
Orientation:
Plus strand

Genomic View for ZNF736 Gene

Genes around ZNF736 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF736 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF736 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF736 Gene

Proteins for ZNF736 Gene

  • Protein details for ZNF736 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B4DX44-ZN736_HUMAN
    Recommended name:
    Zinc finger protein 736
    Protein Accession:
    B4DX44

    Protein attributes for ZNF736 Gene

    Size:
    427 amino acids
    Molecular mass:
    49868 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF736 Gene

Post-translational modifications for ZNF736 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF736 Gene

No data available for DME Specific Peptides for ZNF736 Gene

Domains & Families for ZNF736 Gene

Gene Families for ZNF736 Gene

Protein Domains for ZNF736 Gene

Suggested Antigen Peptide Sequences for ZNF736 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

B4DX44

UniProtKB/Swiss-Prot:

ZN736_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 10 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 10 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF736: view

Function for ZNF736 Gene

Molecular function for ZNF736 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF736 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding IBA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF736: view

Phenotypes for ZNF736 Gene

GenomeRNAi human phenotypes for ZNF736:
genes like me logo Genes that share phenotypes with ZNF736: view

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF736 Gene

Localization for ZNF736 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF736 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF736 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF736 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZNF736: view

Pathways & Interactions for ZNF736 Gene

SuperPathways for ZNF736 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF736: view

Pathways by source for ZNF736 Gene

2 Reactome pathways for ZNF736 Gene

Interacting Proteins for ZNF736 Gene

Gene Ontology (GO) - Biological Process for ZNF736 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF736: view

No data available for SIGNOR curated interactions for ZNF736 Gene

Transcripts for ZNF736 Gene

mRNA/cDNA for ZNF736 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(8) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF736 Gene

Zinc finger protein 736:
Representative Sequences:

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF736 Gene

No ASD Table

Relevant External Links for ZNF736 Gene

GeneLoc Exon Structure for
ZNF736
ECgene alternative splicing isoforms for
ZNF736

Expression for ZNF736 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF736 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF736 Gene:

ZNF736

SOURCE GeneReport for Unigene cluster for ZNF736 Gene:

Hs.734771
genes like me logo Genes that share expression patterns with ZNF736: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZNF736 Gene

Orthologs for ZNF736 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF736 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF736 34 35
  • 99.06 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 43 (a)
ManyToMany
-- 35
  • 28 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp85-rs1 35
  • 43 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 39 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 29 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 40 (a)
ManyToMany
-- 35
  • 30 (a)
ManyToMany
-- 35
  • 28 (a)
ManyToMany
-- 35
  • 26 (a)
ManyToMany
-- 35
  • 24 (a)
ManyToMany
-- 35
  • 23 (a)
ManyToMany
-- 35
  • 23 (a)
ManyToMany
-- 35
  • 23 (a)
ManyToMany
Species where no ortholog for ZNF736 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF736 Gene

ENSEMBL:
Gene Tree for ZNF736 (if available)
TreeFam:
Gene Tree for ZNF736 (if available)

Paralogs for ZNF736 Gene

(487) SIMAP similar genes for ZNF736 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF736: view

Variants for ZNF736 Gene

Sequence variations from dbSNP and Humsavar for ZNF736 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10216120 -- 64,347,296(+) TCATT(A/G)CAACC intron-variant
rs10225654 -- 64,337,242(+) GTTTA(C/T)AGCAA intron-variant, utr-variant-3-prime
rs10238846 -- 64,326,175(+) ttttt(A/C)attat intron-variant
rs10239221 -- 64,352,852(+) gggag(A/G)tgcag utr-variant-3-prime
rs10242581 -- 64,341,518(+) ATTTT(C/T)TTGTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF736 Gene

Variant ID Type Subtype PubMed ID
nsv966818 CNV duplication 23825009
nsv958455 CNV deletion 24416366
nsv607310 CNV loss 21841781
nsv607309 CNV loss 21841781
nsv607304 CNV gain 21841781
nsv522412 CNV loss 19592680
nsv518721 CNV loss 19592680
nsv464515 CNV loss 19166990
nsv1137241 CNV deletion 24896259
nsv1019909 CNV gain 25217958
nsv1018858 CNV loss 25217958
nsv1018445 CNV gain 25217958
nsv1016645 CNV gain+loss 25217958
esv3891132 CNV gain 25118596
esv3891131 CNV gain+loss 25118596
esv3613414 CNV loss 21293372
esv3410592 CNV insertion 20981092
esv2764000 CNV gain+loss 21179565
esv2422405 CNV duplication 17116639
dgv6434n100 CNV loss 25217958
dgv240n111 CNV duplication 26073780
dgv1212e199 CNV deletion 23128226
dgv11415n54 CNV loss 21841781
dgv1108n67 CNV loss 20364138
dgv1099e201 CNV deletion 23290073

Variation tolerance for ZNF736 Gene

Gene Damage Index Score: 11.33; 92.64% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF736 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF736

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF736 Gene

Disorders for ZNF736 Gene

Relevant External Links for ZNF736

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF736

No disorders were found for ZNF736 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF736 Gene

Publications for ZNF736 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  3. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ZNF736 Gene

Sources for ZNF736 Gene

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