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Aliases for ZNF732 Gene

Aliases for ZNF732 Gene

  • Zinc Finger Protein 732 2 3 5

External Ids for ZNF732 Gene

Previous GeneCards Identifiers for ZNF732 Gene

  • GC00U922461
  • GC04U900973
  • GC04P000197
  • GC04M000262
  • GC04M000267
  • GC04M000269
  • GC04M000274
  • GC04M000280
  • GC04M000285
  • GC04M000291
  • GC04M000296
  • GC04M000300
  • GC04M000305
  • GC04M000310

Summaries for ZNF732 Gene

GeneCards Summary for ZNF732 Gene

ZNF732 (Zinc Finger Protein 732) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF254.

UniProtKB/Swiss-Prot for ZNF732 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF732 Gene

Genomics for ZNF732 Gene

Regulatory Elements for ZNF732 Gene

Enhancers for ZNF732 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04F001042 1.8 FANTOM5 Ensembl ENCODE 9.7 -738.9 -738852 2.7 HDGF PKNOX1 ARNT SIN3A ZNF2 CBX5 FOS JUNB REST SMARCB1 ZNF141 MIR943 ZNF718 LOC100288172 ZNF732 PCGF3 FGFRL1 LETM1 GAK MAEA
GH04F001040 1.4 FANTOM5 Ensembl ENCODE 12.4 -736.6 -736575 1.8 RING1 SOX13 CTCF KLF1 SAP130 ZIC2 ZFHX2 NR2F6 TRIM24 E2F6 CRIPAK LOC100129917 ZNF141 CTBP1-AS2 ZNF718 ZNF876P ZNF732 LOC100288172 ABCA11P IDUA
GH04F001176 1.4 FANTOM5 Ensembl ENCODE 11.1 -872.8 -872822 2.5 CBX3 THRB RAD21 ZNF48 YY1 GATA2 TBX21 ZNF623 KLF16 SMARCA4 ENSG00000251188 PDE6B CRIPAK ZNF732 RNF212 ENSG00000251639 DGKQ UVSSA GAK ENSG00000273179
GH04F000704 1.1 ENCODE 11.3 -400.9 -400934 2.6 HDGF PKNOX1 ZFP64 ARID4B SIN3A YBX1 ZNF2 ZNF143 ZNF207 SP3 ENSG00000207009 LOC100129917 ZNF718 ZNF141 ENSG00000272588 PCGF3 ZNF732 IDUA CTBP1-AS2 CRIPAK
GH04F001009 1 ENCODE 12.4 -705.0 -705034 2.0 HDGF PKNOX1 ZNF48 GLIS2 FOS ZNF263 SP3 SP5 ZNF610 SMARCA4 LOC100129917 ZNF141 CRIPAK ZNF718 ZNF876P CTBP1-AS2 ZNF732 LOC100288172 ABCA11P IDUA
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF732 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF732 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001234239 420 1800 PKNOX1 POLR2A PBX2 MAX SIN3A

Genomic Location for ZNF732 Gene

Chromosome:
4
Start:
270,675 bp from pter
End:
305,321 bp from pter
Size:
34,647 bases
Orientation:
Minus strand

Genomic View for ZNF732 Gene

Genes around ZNF732 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF732 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF732 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF732 Gene

Proteins for ZNF732 Gene

  • Protein details for ZNF732 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B4DXR9-ZN732_HUMAN
    Recommended name:
    Zinc finger protein 732
    Protein Accession:
    B4DXR9

    Protein attributes for ZNF732 Gene

    Size:
    585 amino acids
    Molecular mass:
    67839 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF732 Gene

Post-translational modifications for ZNF732 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF732 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF732 Gene

Domains & Families for ZNF732 Gene

Gene Families for ZNF732 Gene

Protein Domains for ZNF732 Gene

Suggested Antigen Peptide Sequences for ZNF732 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

B4DXR9

UniProtKB/Swiss-Prot:

ZN732_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 16 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 16 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF732: view

Function for ZNF732 Gene

Molecular function for ZNF732 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF732 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding IBA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF732: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF732 Gene

Localization for ZNF732 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF732 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF732 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF732 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZNF732: view

Pathways & Interactions for ZNF732 Gene

SuperPathways for ZNF732 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF732: view

Pathways by source for ZNF732 Gene

2 Reactome pathways for ZNF732 Gene

Interacting Proteins for ZNF732 Gene

Gene Ontology (GO) - Biological Process for ZNF732 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
genes like me logo Genes that share ontologies with ZNF732: view

No data available for SIGNOR curated interactions for ZNF732 Gene

Transcripts for ZNF732 Gene

mRNA/cDNA for ZNF732 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF732 Gene

Zinc finger protein 732:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF732 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d ^ 7 ^ 8
SP1: - -
SP2: - -
SP3: - - -
SP4:
SP5: - - - -

Relevant External Links for ZNF732 Gene

GeneLoc Exon Structure for
ZNF732
ECgene alternative splicing isoforms for
ZNF732

Expression for ZNF732 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF732 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF732 Gene

This gene is overexpressed in Brain - Cerebellum (x4.1).

Protein differential expression in normal tissues from HIPED for ZNF732 Gene

This gene is overexpressed in Liver (68.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF732 Gene



Protein tissue co-expression partners for ZNF732 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF732 Gene:

ZNF732

SOURCE GeneReport for Unigene cluster for ZNF732 Gene:

Hs.698668
genes like me logo Genes that share expression patterns with ZNF732: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF732 Gene

Orthologs for ZNF732 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF732 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF732 34 35
  • 99.2 (n)
mouse
(Mus musculus)
Mammalia Zfp493 35
  • 57 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 52 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 50 (a)
ManyToMany
-- 35
  • 41 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 37 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 51 (a)
ManyToMany
-- 35
  • 44 (a)
ManyToMany
-- 35
  • 39 (a)
ManyToMany
-- 35
  • 36 (a)
ManyToMany
-- 35
  • 35 (a)
ManyToMany
-- 35
  • 33 (a)
ManyToMany
-- 35
  • 33 (a)
ManyToMany
-- 35
  • 29 (a)
ManyToMany
Species where no ortholog for ZNF732 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF732 Gene

ENSEMBL:
Gene Tree for ZNF732 (if available)
TreeFam:
Gene Tree for ZNF732 (if available)

Paralogs for ZNF732 Gene

(517) SIMAP similar genes for ZNF732 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZNF732 Gene

genes like me logo Genes that share paralogs with ZNF732: view

Variants for ZNF732 Gene

Sequence variations from dbSNP and Humsavar for ZNF732 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs10002733 -- 285,607(+) tgagt(A/C)ctcag intron-variant
rs10003142 -- 297,970(+) AGCCT(C/G)CCCAA intron-variant
rs10005733 -- 298,212(+) GTAAC(C/G)CAAAT intron-variant
rs10014959 -- 306,858(+) aagtt(A/C)ttaac downstream-variant-500B, upstream-variant-2KB
rs10019188 -- 305,389(+) gctga(G/T)gctgt upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF732 Gene

Variant ID Type Subtype PubMed ID
nsv966244 CNV duplication 23825009
nsv956428 CNV deletion 24416366
nsv829833 CNV gain 17160897
nsv593198 CNV loss 21841781
nsv593190 CNV gain 21841781
nsv469996 CNV gain 18288195
nsv469736 CNV loss 16826518
nsv1150471 CNV deletion 26484159
nsv1074123 CNV deletion 25765185
nsv1011981 CNV loss 25217958
nsv1011039 CNV loss 25217958
nsv1009336 CNV gain 25217958
nsv1004032 CNV loss 25217958
nsv1001899 CNV loss 25217958
esv4769 OTHER complex 18987735
esv3893862 CNV gain 25118596
esv3893860 CNV loss 25118596
esv3599366 CNV gain 21293372
esv2763816 CNV gain+loss 21179565
esv2673769 CNV deletion 23128226
esv2462495 CNV deletion 19546169
dgv914e199 CNV deletion 23128226
dgv5074n100 CNV loss 25217958
dgv2697n106 CNV deletion 24896259

Variation tolerance for ZNF732 Gene

Residual Variation Intolerance Score: 98.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.95; 68.04% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF732 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF732

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF732 Gene

Disorders for ZNF732 Gene

Relevant External Links for ZNF732

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF732

No disorders were found for ZNF732 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF732 Gene

Publications for ZNF732 Gene

  1. Genome-wide association study of antibody response to smallpox vaccine. (PMID: 22542470) Ovsyannikova I.G. … Poland G.A. (Vaccine 2012) 3 64
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64
  4. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3 64

Products for ZNF732 Gene

Sources for ZNF732 Gene

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