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Aliases for ZNF730 Gene

Aliases for ZNF730 Gene

  • Zinc Finger Protein 730 2 3 5

External Ids for ZNF730 Gene

Previous GeneCards Identifiers for ZNF730 Gene

  • GC19P023299
  • GC19P022840
  • GC19P023248

Summaries for ZNF730 Gene

GeneCards Summary for ZNF730 Gene

ZNF730 (Zinc Finger Protein 730) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF718.

UniProtKB/Swiss-Prot for ZNF730 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF730 Gene

Genomics for ZNF730 Gene

Regulatory Elements for ZNF730 Gene

Enhancers for ZNF730 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF730 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF730 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF730 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF730 Gene

Chromosome:
19
Start:
23,075,210 bp from pter
End:
23,147,219 bp from pter
Size:
72,010 bases
Orientation:
Plus strand

Genomic View for ZNF730 Gene

Genes around ZNF730 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF730 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF730 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF730 Gene

Proteins for ZNF730 Gene

  • Protein details for ZNF730 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZMV8-ZN730_HUMAN
    Recommended name:
    Putative zinc finger protein 730
    Protein Accession:
    Q6ZMV8

    Protein attributes for ZNF730 Gene

    Size:
    503 amino acids
    Molecular mass:
    59040 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF730 Gene

Proteomics data for ZNF730 Gene at MOPED

Post-translational modifications for ZNF730 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF730 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF730 Gene

Domains & Families for ZNF730 Gene

Gene Families for ZNF730 Gene

Protein Domains for ZNF730 Gene

Suggested Antigen Peptide Sequences for ZNF730 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZMV8

UniProtKB/Swiss-Prot:

ZN730_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF730: view

Function for ZNF730 Gene

Molecular function for ZNF730 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF730 Gene

Localization for ZNF730 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF730 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF730 Gene COMPARTMENTS Subcellular localization image for ZNF730 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF730 Gene

Pathways & Interactions for ZNF730 Gene

SuperPathways for ZNF730 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF730: view

Pathways by source for ZNF730 Gene

2 Reactome pathways for ZNF730 Gene

Interacting Proteins for ZNF730 Gene

Gene Ontology (GO) - Biological Process for ZNF730 Gene

None

No data available for SIGNOR curated interactions for ZNF730 Gene

Drugs & Compounds for ZNF730 Gene

No Compound Related Data Available

Transcripts for ZNF730 Gene

mRNA/cDNA for ZNF730 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF730 Gene

Zinc finger protein 730:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF730 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c
SP1: -
SP2:
SP3: - -

Relevant External Links for ZNF730 Gene

GeneLoc Exon Structure for
ZNF730
ECgene alternative splicing isoforms for
ZNF730

Expression for ZNF730 Gene

mRNA expression in normal human tissues for ZNF730 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF730 Gene

This gene is overexpressed in Testis (x15.3).

SOURCE GeneReport for Unigene cluster for ZNF730 Gene Hs.427120

genes like me logo Genes that share expression patterns with ZNF730: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF730 Gene

Orthologs for ZNF730 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF730 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF730 35
  • 98.28 (n)
  • 97.42 (a)
ZNF730 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 51 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 36 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 35 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Rsl1 36
  • 42 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 49 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 38 (a)
ManyToMany
-- 36
  • 35 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
-- 36
  • 26 (a)
ManyToMany
Species with no ortholog for ZNF730:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF730 Gene

ENSEMBL:
Gene Tree for ZNF730 (if available)
TreeFam:
Gene Tree for ZNF730 (if available)

Paralogs for ZNF730 Gene

(497) SIMAP similar genes for ZNF730 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF730: view

Variants for ZNF730 Gene

Sequence variations from dbSNP and Humsavar for ZNF730 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs7247102 - 23,146,138(+) TGGAG(A/G)GAAAC reference, missense
rs7256177 -- 23,127,061(+) ATTCT(A/G)TTGTA intron-variant
rs7257716 -- 23,144,912(+) TGTAT(A/G)TGCCA intron-variant
rs7507433 -- 23,121,779(+) CTGAA(A/G)TTCAG intron-variant
rs7507929 -- 23,116,174(+) AGGTC(A/C)AGACT upstream-variant-2KB

Variation tolerance for ZNF730 Gene

Residual Variation Intolerance Score: 91.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.81; 58.40% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for ZNF730 Gene

Disorders for ZNF730 Gene

Relevant External Links for ZNF730

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF730

No disorders were found for ZNF730 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF730 Gene

Publications for ZNF730 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 67

Products for ZNF730 Gene

Sources for ZNF730 Gene

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