Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF730 Gene

Aliases for ZNF730 Gene

  • Zinc Finger Protein 730 2 3

External Ids for ZNF730 Gene

Previous GeneCards Identifiers for ZNF730 Gene

  • GC19P023299
  • GC19P022840
  • GC19P023248

Summaries for ZNF730 Gene

GeneCards Summary for ZNF730 Gene

ZNF730 (Zinc Finger Protein 730) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF253.

UniProtKB/Swiss-Prot for ZNF730 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF730 Gene

Genomics for ZNF730 Gene

Regulatory Elements for ZNF730 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF730 Gene

23,075,210 bp from pter
23,149,961 bp from pter
74,752 bases
Plus strand

Genomic View for ZNF730 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF730 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF730 Gene

Proteins for ZNF730 Gene

  • Protein details for ZNF730 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative zinc finger protein 730
    Protein Accession:
    Secondary Accessions:

    Protein attributes for ZNF730 Gene

    503 amino acids
    Molecular mass:
    59040 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF730 Gene

Proteomics data for ZNF730 Gene at MOPED

Post-translational modifications for ZNF730 Gene

  • Ubiquitination at Lys282 and Lys285
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF730 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF730 Gene

Domains for ZNF730 Gene

Gene Families for ZNF730 Gene

  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF730 Gene

Suggested Antigen Peptide Sequences for ZNF730 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q6ZMV8
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF730: view

Function for ZNF730 Gene

Molecular function for ZNF730 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF730 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF730: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF730 Gene

Localization for ZNF730 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF730 Gene

Subcellular locations from

Jensen Localization Image for ZNF730 Gene COMPARTMENTS Subcellular localization image for ZNF730 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF730 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF730: view

Pathways for ZNF730 Gene

SuperPathways for ZNF730 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF730: view

Pathways by source for ZNF730 Gene

2 Reactome pathways for ZNF730 Gene

Interacting Proteins for ZNF730 Gene

Gene Ontology (GO) - Biological Process for ZNF730 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF730: view

Transcripts for ZNF730 Gene

mRNA/cDNA for ZNF730 Gene

(1) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF730 Gene

Zinc finger protein 730:
Representative Sequences:

CRISPR Products

miRNA Products

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF730 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c
SP1: -
SP3: - -

Relevant External Links for ZNF730 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF730 Gene

mRNA expression in normal human tissues for ZNF730 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF730 Gene

This gene is overexpressed in Testis (15.3).

SOURCE GeneReport for Unigene cluster for ZNF730 Gene Hs.427120

genes like me logo Genes that share expressions with ZNF730: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for ZNF730 Gene

Orthologs for ZNF730 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF730 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF730 35
  • 98.28 (n)
  • 97.42 (a)
ZNF730 36
  • 98 (a)
(Bos Taurus)
Mammalia -- 36
  • 51 (a)
(Canis familiaris)
Mammalia -- 36
  • 36 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 35 (a)
-- 36
  • 53 (a)
(Mus musculus)
Mammalia Rsl1 36
  • 42 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 49 (a)
-- 36
  • 31 (a)
-- 36
  • 38 (a)
-- 36
  • 35 (a)
-- 36
  • 29 (a)
-- 36
  • 29 (a)
-- 36
  • 28 (a)
-- 36
  • 26 (a)
Species with no ortholog for ZNF730:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF730 Gene

Gene Tree for ZNF730 (if available)
Gene Tree for ZNF730 (if available)

Paralogs for ZNF730 Gene

Selected SIMAP similar genes for ZNF730 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF730: view

Variants for ZNF730 Gene

Sequence variations from dbSNP and Humsavar for ZNF730 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs8812 -- 23,127,140(+) TGATA(C/T)TCCAA intron-variant
rs434878 -- 23,128,879(+) gccca(C/G)ggctc intron-variant
rs444059 -- 23,128,825(+) ccctt(C/T)catca intron-variant
rs453923 -- 23,128,850(+) taaaa(A/G)aaaaa intron-variant
rs1037993 -- 23,124,004(+) ATACT(G/T)CTCCC intron-variant

Relevant External Links for ZNF730 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF730 Gene

Disorders for ZNF730 Gene

No disorders were found for ZNF730 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ZNF730 Gene

Publications for ZNF730 Gene

  1. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for ZNF730 Gene

Sources for ZNF730 Gene

Back to Top