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Aliases for ZNF729 Gene

Aliases for ZNF729 Gene

  • Zinc Finger Protein 729 2 3

External Ids for ZNF729 Gene

Previous GeneCards Identifiers for ZNF729 Gene

  • GC00U921783
  • GC19U900716
  • GC19P022486

Summaries for ZNF729 Gene

GeneCards Summary for ZNF729 Gene

ZNF729 (Zinc Finger Protein 729) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF208.

UniProtKB/Swiss-Prot for ZNF729 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF729 Gene

Genomics for ZNF729 Gene

Genomic Location for ZNF729 Gene

Chromosome:
19
Start:
22,286,408 bp from pter
End:
22,317,176 bp from pter
Size:
30,769 bases
Orientation:
Plus strand

Genomic View for ZNF729 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF729 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF729 Gene

No data available for Regulatory Elements for ZNF729 Gene

Proteins for ZNF729 Gene

  • Protein details for ZNF729 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NN14-ZN729_HUMAN
    Recommended name:
    Zinc finger protein 729
    Protein Accession:
    A6NN14
    Secondary Accessions:
    • M0QY45

    Protein attributes for ZNF729 Gene

    Size:
    1252 amino acids
    Molecular mass:
    145022 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF729 Gene

Proteomics data for ZNF729 Gene at MOPED

Post-translational modifications for ZNF729 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF729 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF729 Gene

Domains & Families for ZNF729 Gene

Gene Families for ZNF729 Gene

Protein Domains for ZNF729 Gene

Suggested Antigen Peptide Sequences for ZNF729 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NN14

UniProtKB/Swiss-Prot:

ZN729_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 37 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 37 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF729: view

Function for ZNF729 Gene

Molecular function for ZNF729 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF729 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF729: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF729 Gene

Localization for ZNF729 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF729 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF729 Gene COMPARTMENTS Subcellular localization image for ZNF729 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF729 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF729: view

Pathways & Interactions for ZNF729 Gene

SuperPathways for ZNF729 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF729: view

Pathways by source for ZNF729 Gene

2 Reactome pathways for ZNF729 Gene

Interacting Proteins for ZNF729 Gene

Gene Ontology (GO) - Biological Process for ZNF729 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF729: view

No data available for SIGNOR curated interactions for ZNF729 Gene

Drugs & Compounds for ZNF729 Gene

No Compound Related Data Available

Transcripts for ZNF729 Gene

mRNA/cDNA for ZNF729 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF729 Gene

Zinc finger protein 729:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF729 Gene

No ASD Table

Relevant External Links for ZNF729 Gene

GeneLoc Exon Structure for
ZNF729
ECgene alternative splicing isoforms for
ZNF729

Expression for ZNF729 Gene

mRNA expression in normal human tissues for ZNF729 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF729 Gene

This gene is overexpressed in Testis (x45.3).

Protein differential expression in normal tissues from HIPED for ZNF729 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF729 Gene



SOURCE GeneReport for Unigene cluster for ZNF729 Gene Hs.531629

genes like me logo Genes that share expression patterns with ZNF729: view

Protein tissue co-expression partners for ZNF729 Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF729 Gene

Orthologs for ZNF729 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF729 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC100848991 35
  • 64.81 (n)
  • 52.47 (a)
dog
(Canis familiaris)
Mammalia LOC100856035 35
  • 63.27 (n)
  • 53.19 (a)
-- 36
  • 16 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia A530054K11Rik 35
  • 67.31 (n)
  • 59.42 (a)
A530054K11Rik 16
chimpanzee
(Pan troglodytes)
Mammalia ZNF729 35
  • 99.27 (n)
  • 98.65 (a)
ZNF729 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC102551340 35
  • 65.52 (n)
  • 56.65 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 55 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 56 (a)
ManyToMany
-- 36
  • 55 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 46 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 47 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
-- 36
  • 47 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 48 (a)
ManyToMany
-- 36
  • 49 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 50 (a)
ManyToMany
-- 36
  • 48 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
-- 36
  • 46 (a)
ManyToMany
-- 36
  • 46 (a)
ManyToMany
-- 36
  • 44 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
-- 36
  • 46 (a)
ManyToMany
-- 36
  • 56 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 48 (a)
ManyToMany
-- 36
  • 56 (a)
ManyToMany
-- 36
  • 44 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 50 (a)
ManyToMany
-- 36
  • 48 (a)
ManyToMany
-- 36
  • 47 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
-- 36
  • 58 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 37 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 48 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
-- 36
  • 50 (a)
ManyToMany
-- 36
  • 57 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 50 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 50 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
-- 36
  • 52 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101732837 35
  • 55.99 (n)
  • 48.13 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC100537989 35
  • 66.09 (n)
  • 59.77 (a)
AL935044.2 36
  • 48 (a)
ManyToMany
BX005085.3 36
  • 51 (a)
ManyToMany
BX321873.2 36
  • 50 (a)
ManyToMany
BX321887.1 36
  • 45 (a)
ManyToMany
BX324216.1 36
  • 42 (a)
ManyToMany
BX510909.2 36
  • 45 (a)
ManyToMany
BX510909.3 36
  • 48 (a)
ManyToMany
BX571760.1 36
  • 48 (a)
ManyToMany
BX942815.1 36
  • 52 (a)
ManyToMany
CABZ01021450.1 36
  • 44 (a)
ManyToMany
CABZ01084613.2 36
  • 43 (a)
ManyToMany
CR356223.5 36
  • 45 (a)
ManyToMany
CR847941.1 36
  • 47 (a)
ManyToMany
CR927215.1 36
  • 49 (a)
ManyToMany
CU467646.2 36
  • 46 (a)
ManyToMany
CU929391.1 36
  • 45 (a)
ManyToMany
si:ch211-208f21.5 36
  • 48 (a)
ManyToMany
si:ch211-209p16.3 36
  • 49 (a)
ManyToMany
si:ch211-245n8.1 36
  • 50 (a)
ManyToMany
si:ch73-40a17.5 36
  • 40 (a)
ManyToMany
si:dkey-111k8.1 36
  • 49 (a)
ManyToMany
si:dkey-14o6.6 36
  • 50 (a)
ManyToMany
si:dkey-15h8.4 36
  • 45 (a)
ManyToMany
si:dkey-196n19.7 36
  • 45 (a)
ManyToMany
si:dkey-240n22.7 36
  • 46 (a)
ManyToMany
si:dkey-77f5.7 36
  • 20 (a)
ManyToMany
si:dkey-92c21.3 36
  • 49 (a)
ManyToMany
zgc:113100 36
  • 51 (a)
ManyToMany
zgc:113381 36
  • 42 (a)
ManyToMany
zgc:171418 36
  • 52 (a)
ManyToMany
zgc:171570 36
  • 45 (a)
ManyToMany
zgc:174234 36
  • 44 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta Oaz 36
  • 13 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 46 (a)
ManyToMany
-- 36
  • 40 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
-- 36
  • 48 (a)
ManyToMany
-- 36
  • 47 (a)
ManyToMany
-- 36
  • 47 (a)
ManyToMany
CSA.11281 36
  • 43 (a)
ManyToMany
Species with no ortholog for ZNF729:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF729 Gene

ENSEMBL:
Gene Tree for ZNF729 (if available)
TreeFam:
Gene Tree for ZNF729 (if available)

Paralogs for ZNF729 Gene

Paralogs for ZNF729 Gene

(496) SIMAP similar genes for ZNF729 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for ZNF729 Gene

genes like me logo Genes that share paralogs with ZNF729: view

Variants for ZNF729 Gene

Sequence variations from dbSNP and Humsavar for ZNF729 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1962867 -- 22,312,798(-) AGGCG(A/G)AGGTT intron-variant
rs2116919 -- 22,308,904(-) tctct(C/G)tatct intron-variant
rs4932755 -- 22,312,014(+) cttat(A/G)aacct intron-variant
rs4932974 -- 22,307,813(+) TTTTT(G/T)TTTTT intron-variant
rs4932975 -- 22,308,270(+) gttaa(C/T)aggca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF729 Gene

Variant ID Type Subtype PubMed ID
esv4924 CNV Complex 18987735
esv2718335 CNV Deletion 23290073
dgv552e201 CNV Deletion 23290073
dgv3808n71 CNV Gain 21882294
dgv1066e1 CNV Complex 17122850
esv731 CNV CNV 17122850
esv34340 CNV Loss 17911159
dgv553e201 CNV Deletion 23290073
dgv633e199 CNV Deletion 23128226
nsv436853 CNV Insertion 17901297
nsv525240 CNV Gain 19592680
dgv3813n71 CNV Gain 21882294
dgv3814n71 CNV Gain 21882294
nsv833786 CNV Gain 17160897
dgv3n43 CNV Gain 19587683
nsv911441 CNV Gain 21882294
nsv469671 CNV Complex 16826518

Variation tolerance for ZNF729 Gene

Residual Variation Intolerance Score: 96.87% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.73; 73.26% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF729 Gene

HapMap Linkage Disequilibrium report
ZNF729

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF729 Gene

Disorders for ZNF729 Gene

Relevant External Links for ZNF729

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF729
genes like me logo Genes that share disorders with ZNF729: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF729 Gene

Publications for ZNF729 Gene

  1. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 67
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 67

Products for ZNF729 Gene

Sources for ZNF729 Gene

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