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Aliases for ZNF728 Gene

Aliases for ZNF728 Gene

  • Zinc Finger Protein 728 2 3

External Ids for ZNF728 Gene

Previous GeneCards Identifiers for ZNF728 Gene

  • GC19U900615
  • GC19M023157

Summaries for ZNF728 Gene

GeneCards Summary for ZNF728 Gene

ZNF728 (Zinc Finger Protein 728) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF253.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF728 Gene

Genomics for ZNF728 Gene

Regulatory Elements for ZNF728 Gene

Transcription factor binding sites by QIAGEN in the ZNF728 gene promoter:

Genomic Location for ZNF728 Gene

22,973,664 bp from pter
23,003,208 bp from pter
29,545 bases
Minus strand

Genomic View for ZNF728 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF728 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF728 Gene

Proteins for ZNF728 Gene

  • Protein details for ZNF728 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 728
    Protein Accession:
    Secondary Accessions:

    Protein attributes for ZNF728 Gene

    622 amino acids
    Molecular mass:
    71801 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF728 Gene

Proteomics data for ZNF728 Gene at MOPED

Post-translational modifications for ZNF728 Gene

  • Ubiquitination at Lys319 and Lys425
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF728 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF728 Gene

Domains for ZNF728 Gene

Gene Families for ZNF728 Gene

  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF728 Gene

Graphical View of Domain Structure for InterPro Entry



  • P0DKX0
  • Contains 1 KRAB domain.
  • Contains 14 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF728: view

No data available for Suggested Antigen Peptide Sequences for ZNF728 Gene

Function for ZNF728 Gene

Gene Ontology (GO) - Molecular Function for ZNF728 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF728: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF728 Gene

Localization for ZNF728 Gene

Gene Ontology (GO) - Cellular Components for ZNF728 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with ZNF728: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for ZNF728 Gene

Pathways for ZNF728 Gene

SuperPathways for ZNF728 Gene

No Data Available

Interacting Proteins for ZNF728 Gene

Gene Ontology (GO) - Biological Process for ZNF728 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF728: view

No data available for Pathways by source for ZNF728 Gene

Transcripts for ZNF728 Gene

mRNA/cDNA for ZNF728 Gene

(2) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF728 Gene

Zinc finger protein 728:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF728

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF728 Gene

No ASD Table

Relevant External Links for ZNF728 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF728 Gene

mRNA expression in normal human tissues for ZNF728 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF728 Gene

This gene is overexpressed in Testis (14.0).

SOURCE GeneReport for Unigene cluster for ZNF728 Gene Hs.616766

genes like me logo Genes that share expressions with ZNF728: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for ZNF728 Gene

Orthologs for ZNF728 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF728 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 36
  • 55 (a)
(Canis familiaris)
Mammalia -- 36
  • 40 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 40 (a)
-- 36
  • 51 (a)
(Mus musculus)
Mammalia Zfp273 36
  • 59 (a)
(Pan troglodytes)
Mammalia -- 36
  • 67 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 53 (a)
-- 36
  • 38 (a)
-- 36
  • 46 (a)
-- 36
  • 39 (a)
-- 36
  • 36 (a)
-- 36
  • 35 (a)
-- 36
  • 34 (a)
-- 36
  • 29 (a)
Species with no ortholog for ZNF728:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF728 Gene

Gene Tree for ZNF728 (if available)
Gene Tree for ZNF728 (if available)

Paralogs for ZNF728 Gene

Selected SIMAP similar genes for ZNF728 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF728: view

Variants for ZNF728 Gene

Sequence variations from dbSNP and Humsavar for ZNF728 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs167034 -- 22,986,264(-) CATAC(A/G)TCAAG intron-variant
rs167035 -- 22,984,491(-) acctc(C/T)gcctc intron-variant
rs176456 -- 22,984,164(-) tttgg(A/C)ctaag intron-variant
rs188343 -- 23,003,395(-) caaac(C/T)gatgg upstream-variant-2KB
rs190869 -- 23,000,877(+) aaaaa(A/C)aaaaa intron-variant

Relevant External Links for ZNF728 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF728 Gene

Disorders for ZNF728 Gene

No disorders were found for ZNF728 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ZNF728 Gene

Publications for ZNF728 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  4. A genome-wide association study (GWAS) for bronchopulmonary dysplasia. (PMID: 23897914) Wang H. … O'Brodovich H.M. (Pediatrics 2013) 3
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4

Products for ZNF728 Gene

Sources for ZNF728 Gene

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