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Aliases for ZNF728 Gene

Aliases for ZNF728 Gene

  • Zinc Finger Protein 728 2 3 5

External Ids for ZNF728 Gene

Previous GeneCards Identifiers for ZNF728 Gene

  • GC19U900615
  • GC19M023157

Summaries for ZNF728 Gene

GeneCards Summary for ZNF728 Gene

ZNF728 (Zinc Finger Protein 728) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF718.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF728 Gene

Genomics for ZNF728 Gene

Regulatory Elements for ZNF728 Gene

Enhancers for ZNF728 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF728 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the ZNF728 gene promoter:

Genomic Location for ZNF728 Gene

Chromosome:
19
Start:
22,974,883 bp from pter
End:
23,003,208 bp from pter
Size:
28,326 bases
Orientation:
Minus strand

Genomic View for ZNF728 Gene

Genes around ZNF728 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF728 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF728 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF728 Gene

Proteins for ZNF728 Gene

  • Protein details for ZNF728 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0DKX0-ZN728_HUMAN
    Recommended name:
    Zinc finger protein 728
    Protein Accession:
    P0DKX0

    Protein attributes for ZNF728 Gene

    Size:
    622 amino acids
    Molecular mass:
    71801 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF728 Gene

Proteomics data for ZNF728 Gene at MOPED

Post-translational modifications for ZNF728 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF728 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF728 Gene

Domains & Families for ZNF728 Gene

Gene Families for ZNF728 Gene

Protein Domains for ZNF728 Gene

Graphical View of Domain Structure for InterPro Entry

P0DKX0

UniProtKB/Swiss-Prot:

ZN728_HUMAN :
  • Contains 1 KRAB domain.
  • Contains 14 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Similarity:
  • Contains 14 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF728: view

No data available for Suggested Antigen Peptide Sequences for ZNF728 Gene

Function for ZNF728 Gene

Gene Ontology (GO) - Molecular Function for ZNF728 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
genes like me logo Genes that share ontologies with ZNF728: view

Phenotypes for ZNF728 Gene

genes like me logo Genes that share phenotypes with ZNF728: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF728 Gene

Localization for ZNF728 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ZNF728 Gene

Pathways & Interactions for ZNF728 Gene

SuperPathways for ZNF728 Gene

No Data Available

Interacting Proteins for ZNF728 Gene

Gene Ontology (GO) - Biological Process for ZNF728 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZNF728 Gene

Drugs & Compounds for ZNF728 Gene

No Compound Related Data Available

Transcripts for ZNF728 Gene

mRNA/cDNA for ZNF728 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF728 Gene

Zinc finger protein 728:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF728 Gene

No ASD Table

Relevant External Links for ZNF728 Gene

GeneLoc Exon Structure for
ZNF728
ECgene alternative splicing isoforms for
ZNF728

Expression for ZNF728 Gene

mRNA expression in normal human tissues for ZNF728 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF728 Gene

This gene is overexpressed in Testis (x14.0).

SOURCE GeneReport for Unigene cluster for ZNF728 Gene Hs.616766

genes like me logo Genes that share expression patterns with ZNF728: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF728 Gene

Orthologs for ZNF728 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF728 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 55 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 40 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 40 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp273 36
  • 59 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 67 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 53 (a)
ManyToMany
-- 36
  • 38 (a)
ManyToMany
-- 36
  • 46 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
-- 36
  • 36 (a)
ManyToMany
-- 36
  • 35 (a)
ManyToMany
-- 36
  • 34 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
Species with no ortholog for ZNF728:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF728 Gene

ENSEMBL:
Gene Tree for ZNF728 (if available)
TreeFam:
Gene Tree for ZNF728 (if available)

Paralogs for ZNF728 Gene

(530) SIMAP similar genes for ZNF728 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF728: view

Variants for ZNF728 Gene

Sequence variations from dbSNP and Humsavar for ZNF728 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs771353 -- 23,004,765(+) tacaa(A/G)cgtga upstream-variant-2KB
rs771354 -- 23,005,103(+) cagac(A/C)catgc upstream-variant-2KB
rs12984262 -- 22,989,052(+) atctc(A/C)aaaaa intron-variant, upstream-variant-2KB
rs12984623 -- 23,003,532(+) agcta(C/T)tcagg upstream-variant-2KB
rs8104964 -- 22,979,622(+) aggtc(A/G)agata intron-variant

Variation tolerance for ZNF728 Gene

Residual Variation Intolerance Score: 79% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.76; 91.60% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF728 Gene

HapMap Linkage Disequilibrium report
ZNF728

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF728 Gene

Disorders for ZNF728 Gene

Relevant External Links for ZNF728

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF728

No disorders were found for ZNF728 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF728 Gene

Publications for ZNF728 Gene

  1. A genome-wide association study (GWAS) for bronchopulmonary dysplasia. (PMID: 23897914) Wang H. … O'Brodovich H.M. (Pediatrics 2013) 3 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF728 Gene

Sources for ZNF728 Gene

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